Colonization and infection in surgical intensive care patients--a prospective study.

abstract：BACKGROUND:After resuscitation, asphyxiated neonates often develop poor cardiac function with hypotension, pulmonary hypertension and multiorgan ischemia. In a swine model of neonatal hypoxia-reoxygenation, effects of epinephrine, dobutamine and milrinone on systemic, pulmonary and regional hemodynamics and oxygen tran...

journal_title：Intensive care medicine

authors： Joynt C,Bigam DL,Charrois G,Jewell LD,Korbutt G,Cheung PY

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To present our observation of the development of a rare nail deformity in the prolonged course of disease of a critically ill patient with a pulmonary abscess. DESIGN:Case report. SETTING:Tertiary referral, 16-bed, level I surgical ICU in an academic hospital. PATIENT:A 48-year-old Caucasian male was treat...

journal_title：Intensive care medicine

authors： Wester JP,van Eps RS,Stouthamer A,Girbes AR

更新日期：2000-11-01 00:00:00

abstract：:In order to evaluate the in vitro activity of fleroxacin against nosocomial gram-negative organisms, 263 multiresistant gram-negative bacilli (203 Enterobacteriaceae and 60 non-fermenting gram-negative bacilli) were isolated from adult patients with nosocomial infections. The different patterns of resistance to eight ...

journal_title：Intensive care medicine

authors： Araque M,Velazco E

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To quantify the variability in the concentration of drug infusions prepared on an intensive care unit and establish whether there was a relationship between the quality of syringe labeling and drug preparation. DESIGN:Audit carried out over 3 weeks in May 2006 and completed in May 2007. SETTING:The adult ne...

journal_title：Intensive care medicine

authors： Wheeler DW,Degnan BA,Sehmi JS,Burnstein RM,Menon DK,Gupta AK

更新日期：2008-08-01 00:00:00

abstract：:The effects of 142 intravenous boluses of althesin (0.05 ml/kg) on cerebral perfusion pressure (CPP) were studied in twelve head injured comatose patients. The data were divided into those where the mean pre-bolus intracranial pressure (ICP) was above or below 20 mmHg and then subdivided into those where the minimum p...

journal_title：Intensive care medicine

authors： Procaccio F,Bingham RM,Hinds CJ,Prior PF

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To analyze the effects of polymyxin B-immobilized fiber (PMX-F) on bone resorption in septic patients. DESIGN AND SETTING:Observational prospective study in intensive care units of a general hospital. PATIENTS AND PARTICIPANTS:25 patients with severe sepsis and 20 healthy controls. MEASUREMENTS AND RESULTS...

journal_title：Intensive care medicine

authors： Nakamura T,Kawagoe Y,Matsuda T,Koide H

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:Organophosphate toxicity is the leading cause of morbidity and death in poisoning by insecticides. The clinical symptoms of pesticide toxicity range from the classic cholinergic syndrome to flaccid paralysis and intractable seizures. The mainstays of therapy are atropine, oximes, benzodiazepines and supportiv...

journal_title：Intensive care medicine

authors： Hoffmann U,Papendorf T

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:Definition of the changes in the activators of plasminogen, u-PA and t-PA, and examination of the possible generation of plasmin in the circulation in overwhelming sepsis. DESIGN:Serial blood analysis starting 4 h after development of symptoms of toxic shock syndrome. SETTING:Intensive care unit. PATIENT:A...

journal_title：Intensive care medicine

authors： Haj MA,Robbie LA,Croll A,Adey GD,Bennett B

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:To study the pharmacokinetics and local tissue effects resulting from the intratracheal administration of preservative-free fentanyl. DESIGN:Prospective, randomized, blinded and controlled animal study. SETTING:University research laboratory. SUBJECTS:Eighteen adult male New Zealand rabbits. INTERVENTIONS...

journal_title：Intensive care medicine

authors： Irazuzta JE,Ahmed U,Gancayco A,Ahmed ST,Zhang J,Anand KJ

更新日期：1996-02-01 00:00:00

abstract：:The purpose of this study was noninvasive assessment of respiratory compliance and resistance in mechanically ventilated patients with acute respiratory failure (ARF). To this end, flow, change in lung volume, and airway pressure were measured at the proximal tip of the endotracheal tubes in twenty nine critically ill...

journal_title：Intensive care medicine

authors： Bernasconi M,Ploysongsang Y,Gottfried SB,Milic-Emili J,Rossi A

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:Endotoxin administration to humans is a common means to study systemic inflammation. Worldwide, thousands of volunteers have received endotoxin, and adverse events are rarely reported. The aim of this report was to increase awareness of specific risks of the intravenous administration of endotoxin to human vo...

journal_title：Intensive care medicine

authors： van Eijk LT,Pickkers P,Smits P,Bouw MP,van der Hoeven JG

更新日期：2004-12-01 00:00:00

abstract：INTRODUCTION:Faecal peritonitis (FP) is a common cause of sepsis and admission to the intensive care unit (ICU). The Genetics of Sepsis and Septic Shock in Europe (GenOSept) project is investigating the influence of genetic variation on the host response and outcomes in a large cohort of patients with sepsis admitted t...

journal_title：Intensive care medicine

authors： Tridente A,Clarke GM,Walden A,McKechnie S,Hutton P,Mills GH,Gordon AC,Holloway PA,Chiche JD,Bion J,Stuber F,Garrard C,Hinds CJ,GenOSept Investigators.

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To document the costs and outcomes of the various forms of the septic syndromes [systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis, septic shock), particularly those associated with infection acquired in an intensive care unit (ICU). DESIGN:Prospective data collection for all septic patie...

journal_title：Intensive care medicine

authors： Brun-Buisson C,Roudot-Thoraval F,Girou E,Grenier-Sennelier C,Durand-Zaleski I

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:Patients undergoing cardiac surgery often require transfusions of red blood cells, plasma and platelets. These components differ widely in both indications for use and composition. However, from a statistical point of view there is a significant colinearity between the components. This study explores the relati...

journal_title：Intensive care medicine

authors： Bjursten H,Dardashti A,Ederoth P,Brondén B,Algotsson L

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:Clinical examination is often the first step to diagnose shock and estimate cardiac index. In the Simple Intensive Care Studies-I, we assessed the association and diagnostic performance of clinical signs for estimation of cardiac index in critically ill patients. METHODS:In this prospective, single-centre coho...

journal_title：Intensive care medicine

authors： Hiemstra B,Koster G,Wiersema R,Hummel YM,van der Harst P,Snieder H,Eck RJ,Kaufmann T,Scheeren TWL,Perner A,Wetterslev J,de Smet AMGA,Keus F,van der Horst ICC,SICS Study Group.

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To evaluate compliance with recommended patient-care practices for the prevention of hospital-acquired infections (HAI) in the intensive care unit (ICU). DESIGN:European descriptive survey by questionnaire mailed to all the directors of ICUs. PATIENTS AND PARTICIPANTS:A total of 1642 general ICUs with more ...

journal_title：Intensive care medicine

authors： Moro ML,Jepsen OB

更新日期：1996-09-01 00:00:00

abstract：PURPOSE:Meconium aspiration syndrome (MAS) is a life-threatening neonatal lung injury, whose pathophysiology has been mainly studied in animal models. In such models, pancreatic secretory phospholipase A2 (sPLA2-IB) and proinflammatory cytokines present in meconium challenge the lungs, catabolising surfactant and harmi...

journal_title：Intensive care medicine

authors： De Luca D,Minucci A,Tripodi D,Piastra M,Pietrini D,Zuppi C,Conti G,Carnielli VP,Capoluongo E

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of minitracheotomy (MT) insertion for intratracheal oxygen insufflation (ITO2) on arterial blood gases and survival in patients with respiratory failure from chronic lung disease. DESIGN:Open, prospective clinical study. SETTING:A 12-bed medical intensive care unit in a non-universi...

journal_title：Intensive care medicine

authors： Andrivet P,Richard G,Viau F,Letinier JY,Darne C,Vu Ngoc C

更新日期：1996-12-01 00:00:00

abstract：:In the first study 6 patients with raised intracranial pressure due to brain oedema following head injury were given dihydroergotamine because of low perfusion pressure. The intracranial pressure fell simultaneously with the increase in arterial pressure. The intracranial pressure fell from 24 +/- 2 mmHg by a maximum ...

journal_title：Intensive care medicine

authors： Grände PO

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:To analyze the effect of endothelin-1 on pulmonary arterial and venous contractile force in vitro and on up- and downstream pulmonary vascular resistance in vivo under sham and endotoxemic conditions in pigs. MATERIALS AND METHODS:In vitro: paired preparations of pulmonary arteries and veins were mounted in ...

journal_title：Intensive care medicine

authors： Rossi P,Persson B,Boels PJ,Arner A,Weitzberg E,Oldner A

更新日期：2008-05-01 00:00:00

abstract：:The goals of management of patients with respiratory failure include improving arterial oxygenation with PEEP and red cell transfusion to maintain oxygen carrying capacity, both of which contribute to improving tissue oxygen delivery. However, standard CPD-stored blood is rapidly depleted of 2,3 diphosphoglycerate (2,...

journal_title：Intensive care medicine

authors： Kahn RC,Zaroulis C,Goetz W,Howland WS

更新日期：1986-01-01 00:00:00

abstract：:Placement of a Swan-Ganz catheter can cause many complications. This case report presents a new complication of Swan-Ganz catheter insertion--placement of the Swan-Ganz catheter tip in the coronary sinus. ...

journal_title：Intensive care medicine

authors： Baciewicz FA,Nirdlinger MA,Davis JT

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:The Sonoclot analyser provides global measurement of haemostasis, including plasma coagulation, platelet function and fibrinolysis. Benefits of its use in cardiovascular and hepatic surgery are well-documented and it may be useful in managing obstetric complications. The aim of this study was to determine ran...

journal_title：Intensive care medicine

authors： Kjellberg U,Hellgren M

更新日期：2000-02-01 00:00:00

abstract：:The original version of this article unfortunately contained a mistake. ...

journal_title：Intensive care medicine

authors： Arabi YM,Murthy S,Webb S

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Limiting the duration of invasive ventilation is an important goal in caring for critically ill patients. Several clinical trials have shown that compared to traditional care, protocols can reduce the total duration of mechanical ventilation. Computerized or automated weaning has the potential to improve wea...

journal_title：Intensive care medicine

authors： Burns KE,Lellouche F,Lessard MR

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:Gastrointestinal motility can be impaired by serious illness or medications, compromising enteral feeding in critical care patients. We compared small bowel transit time and morphology in neurosurgical critical care (ICU) patients with those in healthy subjects. METHODS:We evaluated small intestinal transit ti...

journal_title：Intensive care medicine

authors： Rauch S,Krueger K,Turan A,Roewer N,Sessler DI

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:To estimate the direct and indirect (contextual) effects of the factorized constituents of selective digestive decontamination and selective oropharyngeal decontamination (SDD/SOD), being topical antibiotic (TA) and protocolized antifungal prophylaxis (PAFP), on ICU-acquired candidemia. METHODS:A broad range o...

journal_title：Intensive care medicine

authors： Hurley JC

更新日期：2015-11-01 00:00:00

abstract：:Neuromuscular blocking agents (NMBAs) inhibit patient-initiated active breath and the risk of high tidal volumes and consequent high transpulmonary pressure swings, and minimize patient/ ventilator asynchrony in acute respiratory distress syndrome (ARDS). Minimization of volutrauma and ventilator-induced lung injury (...

journal_title：Intensive care medicine

authors： Hraiech S,Yoshida T,Annane D,Duggal A,Fanelli V,Gacouin A,Heunks L,Jaber S,Sottile PD,Papazian L

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of nicotinamide (NIC), an inhibitor of poly(ADP-ribose) synthetase (PARS), on intestinal and liver perfusion, O2 kinetics, and energy metabolism over 24 h of hyperdynamic porcine endotoxemia. DESIGN:Prospective, randomized, controlled experimental study with repeated measures. SET...

journal_title：Intensive care medicine

authors： Theisen M,Träger K,Tugtekin I,Stehr A,Ploner F,Georgieff M,Radermacher P,Matĕjovic M

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:To determine whether, during mechanical ventilation, an optimal positive end-expiratory pressure (PEEP) can be identified by measurement of regional tidal volume and compliance [V (T(reg)), C (RS(reg))]. METHODS:Sixteen anaesthetized intubated neonatal piglets underwent a stepwise vital capacity manoeuvre perf...

journal_title：Intensive care medicine

authors： Dargaville PA,Rimensberger PC,Frerichs I

更新日期：2010-11-01 00:00:00