Determining small intestinal transit time and pathomorphology in critically ill patients using video capsule technology.

Abstract:

PURPOSE:Gastrointestinal motility can be impaired by serious illness or medications, compromising enteral feeding in critical care patients. We compared small bowel transit time and morphology in neurosurgical critical care (ICU) patients with those in healthy subjects. METHODS:We evaluated small intestinal transit time, quality of visualization and intestinal morphology in 16 ICU patients (Glasgow Coma Scale score from 6 to 14) and 16 healthy ambulatory patients. Video data were obtained with PillCam SB capsules (Given Imaging Ltd., Yoqneam, Israel). RESULTS:Transit time was 5.1 h (3.9-7.7) (median [IQR]) in ICU and 4.3 (4.1-5.3 h) in ambulatory patients (P = 0.481). Six ICU patients (37%) and two ambulatory patients (12%) had pathological findings (ulcers, petechia, erosions) (P = 0.10). CONCLUSIONS:Median small bowel transit times in critically ill neurosurgical patients were similar to those in ambulatory subjects, although transit times were more variable in the critically ill patients.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Rauch S,Krueger K,Turan A,Roewer N,Sessler DI

doi

10.1007/s00134-009-1415-6

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

1054-9

issue

6

eissn

0342-4642

issn

1432-1238

journal_volume

35

pub_type

杂志文章
  • Pulse pressure variations adjusted by alveolar driving pressure to assess fluid responsiveness.

    abstract:OBJECTIVE:To evaluate the ability of DeltaPP/DeltaP [pulse pressure variations (DeltaPP) adjusted by alveolar pressure variations (DeltaP = Pplat-PEEPtot)] in predicting fluid responsiveness, to compare its accuracy to that of DeltaPP used alone and to evaluate the influence of tidal volume (Vt) on these two indices. ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-009-1478-4

    authors: Vallée F,Richard JC,Mari A,Gallas T,Arsac E,Verlaan PS,Chousterman B,Samii K,Genestal M,Fourcade O

    更新日期:2009-06-01 00:00:00

  • Auto-PEEP and dynamic hyperinflation in COPD patients during controlled mechanical ventilation and high frequency jet ventilation.

    abstract::We investigated the levels of auto-PEEP and dynamic hyperinflation during high frequency jet ventilation (HFJV) and controlled mechanical ventilation (CMV) in six patients with chronic obstructive pulmonary disease within the first 36 h of acute exacerbation. The comparative evaluation was performed at similar conditi...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF02575298

    authors: Conti G,Bufi M,Rocco M,Calzecchi E,De Blasi RA,Antonelli M,Pelaia P,Gasparetto A

    更新日期:1990-01-01 00:00:00

  • Does continuous heparinization influence platelet function in the intensive care patient?

    abstract:OBJECTIVE:To study the influence of continuous administration of heparin on platelet function in intensive care patients. DESIGN:Prospective, serial investigation. SETTING:Clinical investigation on a surgical and neurosurgical intensive care unit in a university hospital. PATIENTS:The study included 45 patients: 15 ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340050374

    authors: Boldt J,Müller M,Rothe A,Lenzen P,Hempelmann G

    更新日期:1997-05-01 00:00:00

  • Variations in pulmonary artery occlusion pressure to estimate changes in pleural pressure.

    abstract:OBJECTIVE:A readily available assessment of changes in pleural pressure would be useful for ventilator and fluid management in critically ill patients. We examined whether changes in pulmonary artery occlusion pressure (Ppao) adequately reflect respiratory changes in pleural pressure as assessed by changes in intraesop...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-007-0842-5

    authors: Bellemare P,Goldberg P,Magder SA

    更新日期:2007-11-01 00:00:00

  • Is research from databases reliable? Not sure.

    abstract:: ...

    journal_title:Intensive care medicine

    pub_type: 评论,社论

    doi:10.1007/s00134-018-5498-9

    authors: Varkila MRJ,Cremer OL

    更新日期:2019-01-01 00:00:00

  • The effect of iNOS deletion on hepatic gluconeogenesis in hyperdynamic murine septic shock.

    abstract:OBJECTIVE:To investigate the role of the inducible nitric oxide synthase activation-induced excess nitric oxide formation on the rate of hepatic glucose production during fully resuscitated murine septic shock. DESIGN:Prospective, controlled, randomized animal study. SETTING:University animal research laboratory. SU...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-007-0638-7

    authors: Albuszies G,Vogt J,Wachter U,Thiemermann C,Leverve XM,Weber S,Georgieff M,Radermacher P,Barth E

    更新日期:2007-06-01 00:00:00

  • Effects of hemorrhage on gastrointestinal oxygenation.

    abstract:OBJECTIVES:(1) To demonstrate that metabolic parameters are better indicators of tissue hypoxia than regional and whole oxygen consumption (VO(2)). (2) To compare intramucosal pH (pHi) in different gastrointestinal segments. DESIGN:Prospective, interventional study. SETTING:Research laboratory at a university center....

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-001-1138-9

    authors: Dubin A,Estenssoro E,Murias G,Canales H,Sottile P,Badie J,Barán M,Pálizas F,Laporte M,Rivas Díaz M

    更新日期:2001-12-01 00:00:00

  • Beliefs and attitudes of intensive care nurses toward visits and open visiting policy.

    abstract:OBJECTIVE:To describe the beliefs and attitudes of intensive care unit (ICU) nurses toward visiting, visiting hours, and open visiting policies in critical care settings. DESIGN:A descriptive, cross-sectional, multicenter survey. SETTING:Seventeen hospitals in Flanders (Dutch-speaking Belgium), including 30 ICUs. Six...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-007-0599-x

    authors: Berti D,Ferdinande P,Moons P

    更新日期:2007-06-01 00:00:00

  • Impact of two different comorbidity measures on the 6-month mortality of critically ill cancer patients.

    abstract:OBJECTIVE:To evaluate the impact of two different comorbidity measures on the 6-month mortality of severely ill cancer patients. DESIGN AND SETTING:Prospective cohort study in a ten-bed oncological medical-surgical intensive care unit (ICU). PATIENTS:A total of 772 consecutive patients were included over a 45-month p...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-005-2554-z

    authors: Soares M,Salluh JI,Ferreira CG,Luiz RR,Spector N,Rocco JR

    更新日期:2005-03-01 00:00:00

  • Increased RNA editing in children with cyanotic congenital heart disease.

    abstract:PURPOSE:To test the hypothesis that RNA editing is altered in pediatric patients with cyanotic congenital heart disease (CHD) and to determine whether A-to-I RNA editing is associated with the postoperative course following cardiac surgery. Cyanotic CHD is associated with a unique pathophysiology caused by chronic hypo...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-011-2296-z

    authors: Borik S,Simon AJ,Nevo-Caspi Y,Mishali D,Amariglio N,Rechavi G,Paret G

    更新日期:2011-10-01 00:00:00

  • Withdrawal of life support--who should decide? Differences in attitudes among the general public, nurses and physicians.

    abstract:OBJECTIVE:To examine the attitudes of the general public regarding who should decide about the withdrawal of life support and to compare these attitudes with those of intensive care personnel. DESIGN:Nationwide postal questionnaire survey. SETTING:Sweden. PARTICIPANTS:One thousand one hundred ninety-six randomly sel...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340050987

    authors: Sjökvist P,Nilstun T,Svantesson M,Berggren L

    更新日期:1999-09-01 00:00:00

  • Early antibiotic treatment (prophylaxis) of septic complications in severe acute necrotizing pancreatitis: a prospective, randomized, multicenter study comparing two regimens with imipenem-cilastatin.

    abstract:OBJECTIVE:We compared two imipenem regimens for prevention of septic complications in patients with severe acute necrotizing pancreatitis (ANP). DESIGN AND SETTING:Prospective, randomized open clinical trial involving intensive care units of 14 Spanish Hospitals. PARTICIPANTS:92 patients with ANP. INTERVENTIONS:Imip...

    journal_title:Intensive care medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1007/s00134-003-1956-z

    authors: Maraví-Poma E,Gener J,Alvarez-Lerma F,Olaechea P,Blanco A,Domínguez-Muñoz JE,Spanish Group for the Study of Septic Complications in Severe Acute Pancreatitis.

    更新日期:2003-11-01 00:00:00

  • Carbamylated erythropoietin-FC fusion protein and recombinant human erythropoietin during porcine kidney ischemia/reperfusion injury.

    abstract:PURPOSE:To test the hypothesis that a carbamylated EPO-FC fusion protein (cEPO-FC) or recombinant human erythropoietin (rhEPO) would protect against kidney ischemia/reperfusion (I/R) injury in pigs with atherosclerosis. METHODS:Anesthetized and mechanically ventilated animals received cEPO-FC (50 μg kg(-1)), rhEPO (5,...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-012-2766-y

    authors: Matějková Š,Scheuerle A,Wagner F,McCook O,Matallo J,Gröger M,Seifritz A,Stahl B,Vcelar B,Calzia E,Georgieff M,Möller P,Schelzig H,Radermacher P,Simon F

    更新日期:2013-03-01 00:00:00

  • Small dead space heat and moisture exchangers do not impede gas exchange during noninvasive ventilation: a comparison with a heated humidifier.

    abstract:OBJECTIVE:Adverse respiratory and gasometrical effects have been described in patients with acute respiratory failure (ARF) undergoing noninvasive ventilation (NIV) with standard heat and moisture exchangers (HME). We decided to evaluate respiratory parameters and arterial blood gases (ABG) of patients during NIV with ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00134-010-1894-5

    authors: Boyer A,Vargas F,Hilbert G,Gruson D,Mousset-Hovaere M,Castaing Y,Dreyfuss D,Ricard JD

    更新日期:2010-08-01 00:00:00

  • HMGB1 and LPS induce distinct patterns of gene expression and activation in neutrophils from patients with sepsis-induced acute lung injury.

    abstract:OBJECTIVES:Circulating levels of the proinflammatory mediator High Mobility Group Box Protein 1 (HMGB1) are increased in septic patients and may contribute to sepsis-induced organ dysfunction. Although HMGB1 has been shown to activate neutrophils from healthy volunteers, the responses of neutrophils from septic patient...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-007-0748-2

    authors: Silva E,Arcaroli J,He Q,Svetkauskaite D,Coldren C,Nick JA,Poch K,Park JS,Banerjee A,Abraham E

    更新日期:2007-10-01 00:00:00

  • Time course of lung injury in rat acute pancreatitis.

    abstract:OBJECTIVE:Lung injury is a severe complication of acute pancreatitis that increases the mortality rate of the disease. The pathophysiology of acute pancreatitis has been studied in several experimental models, but the kinetics of pulmonary complications in relation to the pancreatic disease is not completely understood...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-006-0264-9

    authors: Morel DR,Frossard JL,Cikirikcioglu B,Tapponnier M,Pastor CM

    更新日期:2006-11-01 00:00:00

  • High-mobility group box 1 protein plasma concentrations during septic shock.

    abstract:OBJECTIVE:To investigate plasma high-mobility group box 1 protein (HMGB1) concentration and its relationship with organ dysfunction and outcome in septic shock patients. DESIGN AND SETTING:Prospective, noninterventional study. Medical adult intensive care unit at a university hospital in France. PATIENTS:42 criticall...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-007-0691-2

    authors: Gibot S,Massin F,Cravoisy A,Barraud D,Nace L,Levy B,Bollaert PE

    更新日期:2007-08-01 00:00:00

  • Research priorities in critical care medicine in the UK.

    abstract:OBJECTIVES:To establish priorities for research in critical care medicine in the UK using survey and nominal group (NG) techniques. DESIGN:The senior doctor and nurse from 325 intensive care units (ICUs) in the UK were invited to contribute up to ten research questions relevant to intensive care organisation, practice...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340000628

    authors: Goldfrad C,Vella K,Bion JF,Rowan KM,Black NA

    更新日期:2000-10-01 00:00:00

  • Modulation of rat brain synaptosomal plasma membrane achieved by atracurium and its metabolite laudanosine.

    abstract:OBJECTIVE:Atracurium besylate and laudanosine cause excitement and seizures when introduced into the central nervous system of laboratory animals. We examined the modulation of lipid-protein interaction in the lipid environment of rat brain synaptosomal plasma membrane (SPM)-bound enzymes as a possible mechanism leadin...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340050605

    authors: Kamper EF,Siafaka J,Stavridis J

    更新日期:1998-05-01 00:00:00

  • Accumulation of hydroxyethyl starch in human and animal tissues: a systematic review.

    abstract:PURPOSE:To systematically review clinical and preclinical data on hydroxyethyl starch (HES) tissue storage. METHODS:MEDLINE (PubMed) was searched and abstracts were screened using defined criteria to identify articles containing original data on HES tissue accumulation. RESULTS:Forty-eight studies were included: 37 h...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-013-3156-9

    authors: Wiedermann CJ,Joannidis M

    更新日期:2014-02-01 00:00:00

  • The epidemiology of infections in intensive care units.

    abstract::This report identifies some of the risk factors underlying the acquisition of hospital infections in patients admitted to Intensive Care Units (ICUs). Infection rates vary in different institutes and in different types of ICUs. Patients are particularly prone to septicaemia and respiratory infections and the underlyin...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/BF01709700

    authors: Emmerson AM

    更新日期:1990-01-01 00:00:00

  • Impact of the humidification device on intubation rate during noninvasive ventilation with ICU ventilators: results of a multicenter randomized controlled trial.

    abstract:PURPOSE:The use of heat and moisture exchangers (HME) during noninvasive ventilation (NIV) can increase the work of breathing, decrease alveolar ventilation, and deliver less humidity in comparison with heated humidifiers (HH). We tested the hypothesis that the use of HH during NIV with ICU ventilators for patients wit...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s00134-013-3145-z

    authors: Lellouche F,L'Her E,Abroug F,Deye N,Rodriguez PO,Rabbat A,Jaber S,Fartoukh M,Conti G,Cracco C,Richard JC,Ricard JD,Mal H,Mentec H,Loisel F,Lacherade JC,Taillé S,Brochard L

    更新日期:2014-02-01 00:00:00

  • The costs of septic syndromes in the intensive care unit and influence of hospital-acquired sepsis.

    abstract:OBJECTIVE:To document the costs and outcomes of the various forms of the septic syndromes [systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis, septic shock), particularly those associated with infection acquired in an intensive care unit (ICU). DESIGN:Prospective data collection for all septic patie...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-003-1877-x

    authors: Brun-Buisson C,Roudot-Thoraval F,Girou E,Grenier-Sennelier C,Durand-Zaleski I

    更新日期:2003-09-01 00:00:00

  • Effect of severe thrombocytopenia on patient outcome after liver transplantation.

    abstract:OBJECTIVE:The objective was to identify factors associated with thrombocytopenia and to assess to what extent thrombocytopenia increases bleeding complications in liver transplant patients. DESIGN:Retrospective study. SETTING:Surgical intensive care unit in a university hospital. PATIENTS:One hundred and sixty-one p...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-003-1727-x

    authors: Ben Hamida C,Lauzet JY,Rézaiguia-Delclaux S,Duvoux C,Cherqui D,Duvaldestin P,Stéphan F

    更新日期:2003-05-01 00:00:00

  • Intensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care.

    abstract:OBJECTIVE:To investigate the effectiveness of an enhanced software Model Predictive Control (eMPC) algorithm for intravenous insulin infusion, targeted at tight glucose control in critically ill patients, over 72 h, in two intensive care units with different management protocols. DESIGN:Comparison with standard care i...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s00134-008-1236-z

    authors: Cordingley JJ,Vlasselaers D,Dormand NC,Wouters PJ,Squire SD,Chassin LJ,Wilinska ME,Morgan CJ,Hovorka R,Van den Berghe G

    更新日期:2009-01-01 00:00:00

  • Serum procalcitonin levels in critically ill patients colonized with Candida spp: new clues for the early recognition of invasive candidiasis?

    abstract:OBJECTIVE:Invasive candidiasis (IC) outcomes in intensive care units (ICUs) could be improved by the early administration of antifungals. The Candida Score (CS) prediction rule has been proposed for the selection of patients who could develop IC. Procalcitonin (PCT) levels allow prompt identification of sepsis, but the...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-009-1623-0

    authors: Charles PE,Castro C,Ruiz-Santana S,León C,Saavedra P,Martín E

    更新日期:2009-12-01 00:00:00

  • Sedation practice and discomfort during withdrawal of mechanical ventilation in critically ill patients at end-of-life: a post-hoc analysis of a multicenter study.

    abstract:PURPOSE:Little is known on the incidence of discomfort during the end-of-life of intensive care unit (ICU) patients and the impact of sedation on such discomfort. The aim of this study was to assess the incidence of discomfort events according to levels of sedation. METHODS:Post-hoc analysis of an observational prospe...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-020-05930-w

    authors: Robert R,Le Gouge A,Kentish-Barnes N,Adda M,Audibert J,Barbier F,Bourcier S,Bourenne J,Boyer A,Devaquet J,Grillet G,Guisset O,Hyacinthe AC,Jourdain M,Lerolle N,Lesieur O,Mercier E,Messika J,Renault A,Vinatier I,Az

    更新日期:2020-06-01 00:00:00

  • Physiological effects of decannulation in tracheostomized patients.

    abstract:OBJECTIVE:To evaluate the physiological effects of decannulation on breathing patterns and respiratory mechanics by comparing mouth breathing (MB) to tracheal breathing (TB) in tracheostomized patients. DESIGN AND SETTING:Prospective cross-over study in a critical and neuromuscular care unit. PATIENTS AND METHODS:Nin...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-002-1545-6

    authors: Chadda K,Louis B,Benaïssa L,Annane D,Gajdos P,Raphaël JC,Lofaso F

    更新日期:2002-12-01 00:00:00

  • Effects of 15-deoxy-Delta12,14-prostaglandin-J2 during hyperdynamic porcine endotoxemia.

    abstract:OBJECTIVE:To investigate the hemodynamic and metabolic effects of the peroxisome proliferator-activated receptor (PPAR)-gamma ligand and nuclear-factor (NF)-kappa B inhibitor 15-deoxy-Delta12,14-prostaglandin-J2 (15d-PGJ2) during long-term, hyperdynamic porcine endotoxemia. DESIGN:Prospective, randomized, controlled e...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-006-0107-8

    authors: Hauser B,Kick J,Iványi Z,Asfar P,Ehrmann U,Muth CM,Albicini M,Wachter U,Vogt J,Bauer M,Brückner UB,Radermacher P,Bracht H

    更新日期:2006-05-01 00:00:00

  • Chapter 5. Essential equipment, pharmaceuticals and supplies. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster.

    abstract:PURPOSE:To provide recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza pandemic or mass disaster with a specific focus on essential equipment, pharmaceuticals and supplies. METHODS:Based on a literature review and expert opinion, a Delphi process was use...

    journal_title:Intensive care medicine

    pub_type: 指南,杂志文章

    doi:10.1007/s00134-010-1763-2

    authors: Sprung CL,Kesecioglu J,European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mass disaster.

    更新日期:2010-04-01 00:00:00