Abstract：
OBJECTIVE:To present our observation of the development of a rare nail deformity in the prolonged course of disease of a critically ill patient with a pulmonary abscess. DESIGN:Case report. SETTING:Tertiary referral, 16-bed, level I surgical ICU in an academic hospital. PATIENT:A 48-year-old Caucasian male was treated with penicillin for a pneumococcal meningitis and pneumonia. He developed a large pulmonary abscess of the right upper lobe and needed prolonged mechanical ventilation. Extensive surgical treatment was successful eventually. A remarkable feature concerned the occurrence of onycholysis of all finger nails and toe nails resulting in complete shedding of the nails (onychomadesis). This phenomenon can be regarded as an extreme manifestation of Beau's lines precipitated by a severe systemic insult. CONCLUSION:We observed the development of onychomadesis in a critically ill patient with a large pulmonary abscess. This association has not been described before.
journal_name
Intensive Care Medjournal_title
Intensive care medicineauthors
Wester JP,van Eps RS,Stouthamer A,Girbes ARdoi
10.1007/s001340000679keywords:
subject
Has Abstractpub_date
2000-11-01 00:00:00pages
1698-700issue
11eissn
0342-4642issn
1432-1238journal_volume
26pub_type
杂志文章abstract：:The effects of 142 intravenous boluses of althesin (0.05 ml/kg) on cerebral perfusion pressure (CPP) were studied in twelve head injured comatose patients. The data were divided into those where the mean pre-bolus intracranial pressure (ICP) was above or below 20 mmHg and then subdivided into those where the minimum p...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF00257469
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE:To describe the beliefs and attitudes of intensive care unit (ICU) nurses toward visiting, visiting hours, and open visiting policies in critical care settings. DESIGN:A descriptive, cross-sectional, multicenter survey. SETTING:Seventeen hospitals in Flanders (Dutch-speaking Belgium), including 30 ICUs. Six...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-007-0599-x
更新日期：2007-06-01 00:00:00
abstract：:A study was conducted to evaluate repeated intrathecal injections of baclofen, without artificial ventilation, in the treatment of severe tetanus. Ten patients, 5 men and 5 women, with a mean age of 34 +/- 7 years, were included in the study. The dose of baclofen injected was 1000 micrograms between the ages of 16 and...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01709840
更新日期：1992-01-01 00:00:00
abstract：:We studied the effect of thiopental loading during resuscitation of 53 patients following cardiopulmonary arrest and compared the outcome with that found in 54 patients treated conventionally in the 30 previous months. Thiopental therapy (10 mg/kg i.v.) was begun within 30 min of the arrest once hemodynamic stability ...
journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章
doi：10.1007/BF00265112
更新日期：1987-01-01 00:00:00
abstract：:Two hundred and seventy-three acute hemorrhagic shocks were treated in 1984 in a pre-hospital emergency care unit. Twenty patients (7%) had a paradoxical bradycardia: they were conscious, 9 of them had an undetectable systolic arterial pressure with the sphygmomanometric method but the femoral pulse was still present....
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF00254705
更新日期：1987-01-01 00:00:00
abstract：OBJECTIVE:Pressure-volume (PV) curves are recorded after induction of complete muscle paralysis, which may limit their clinical use. The feasibility of recording PV curves without paralysis has not been tested. In 19 patients with acute respiratory distress syndrome (ARDS) and no hemodynamic instability we prospectivel...
journal_title：Intensive care medicine
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00134-006-0265-8
更新日期：2006-09-01 00:00:00
abstract：OBJECTIVE:An investigation into the incidence of post-operative complications after thoracic surgery with 3 different physiotherapy masks. DESIGN:A prospective, consecutive, randomized comparison. SETTING:Department of Thoracic and Heart Surgery at a University Hospital. The treatments were performed by experienced a...
journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF01690551
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVE:To investigate whether ultrasound determination of the inferior vena cava diameter (IVCD) and its collapsibility index (IVCCI) could be used to optimize the fluid removal rate while avoiding hypotension during slow continuous ultrafiltration (SCUF). METHODS:Twenty-four consecutive patients [13 men and 11 wom...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-009-1745-4
更新日期：2010-04-01 00:00:00
abstract：:Arrhythmias are extremely common early after AMI. An arrhythmia is defined by exclusion, either because the sequence of myocardial depolarisation is other than normal or because certain arbitrary limits are exceeded. It follows that the term "arrhythmia" encompasses a complex heterogenous group. Although arrhythmias a...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01683131
更新日期：1978-01-01 00:00:00
abstract：:As a result of the previous shortage of tools to assess objectively the overall physiological status of the respiratory system in infants and young children, it has been difficult to measure the degree of physiological disorder or the response to therapy in respiratory diseases such as BPD, the pediatric version of AR...
journal_title：Intensive care medicine
pub_type： 杂志文章,评审
doi：10.1007/BF01704742
更新日期：1995-09-01 00:00:00
abstract：OBJECTIVE:Both serum levels of tumor necrosis factor-alpha (TNF alpha) and interleukin-6 (IL-6) and blood lactate levels in patients with septic shock have been shown to correlate with prognosis. The aim of the study was to define the relative predictive value of these measures. PATIENTS:38 hospitalized patients with ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01712155
更新日期：1996-05-01 00:00:00
abstract：PURPOSE:Septic shock induces a decrease in dendritic cells (DCs) that may contribute to sepsis-induced immunosuppression. We analyzed the time course of circulating DCs in patients with septic shock and its relation to susceptibility to intensive care unit (ICU)-acquired infections. METHODS:We enrolled adult patients ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-011-2306-1
更新日期：2011-09-01 00:00:00
abstract：OBJECTIVE:To investigate the role of the inducible nitric oxide synthase activation-induced excess nitric oxide formation on the rate of hepatic glucose production during fully resuscitated murine septic shock. DESIGN:Prospective, controlled, randomized animal study. SETTING:University animal research laboratory. SU...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-007-0638-7
更新日期：2007-06-01 00:00:00
abstract：PURPOSE:Hyperglycaemia is common in the critically ill. The objectives of this study were to determine the prevalence of critical illness-associated hyperglycaemia (CIAH) and recognised and unrecognised diabetes in the critically ill as well as to evaluate the impact of premorbid glycaemia on the association between ac...
journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章
doi：10.1007/s00134-014-3287-7
更新日期：2014-07-01 00:00:00
abstract：PURPOSE:To characterize the perceived utilization of physical restraint (PR) in mechanically ventilated intensive care unit (ICU) patients and to identify clinical and structural factors influencing PR use. METHODS:A questionnaire was personally handed to one intensivist in 130 ICUs in France then collected on-site 2 ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-012-2715-9
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:To study plasma concentrations of interleukin 6 (IL-6) and interleukin 8 (IL-8) in patients with splanchnic hypoxia, as documented by gastric intramucosal measurements (pH-i), during major abdominal surgery and the relationship between IL-6 and IL-8 concentrations and postoperative complications as well as cl...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340050575
更新日期：1998-04-01 00:00:00
abstract：OBJECTIVES:To establish priorities for research in critical care medicine in the UK using survey and nominal group (NG) techniques. DESIGN:The senior doctor and nurse from 325 intensive care units (ICUs) in the UK were invited to contribute up to ten research questions relevant to intensive care organisation, practice...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340000628
更新日期：2000-10-01 00:00:00
abstract：OBJECTIVE:To identify objective trends of the course of illness that might be used as benchmarks in the auditing of the organization/performance of Intensive Care Units (ICU). DESIGN:Retrospective analysis. PATIENTS AND SETTING:A group of 12,615 patients and 55,464 patient-days prospectively collected in 89 ICUs of 1...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-002-1331-5
更新日期：2002-07-01 00:00:00
abstract：:A 46-year-old man was diagnosed clinically brain dead after sustaining head trauma. The patient was in deep coma, brain nerves were unresponsive and spontaneous breathing was absent. However, EEG showed well preserved activity, but no reactivity to external stimuli. EEG activity disappeared within 40 h. BAEP were high...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF02425159
更新日期：1995-01-01 00:00:00
abstract：:We report the intensive care management of 23 children (age 3-15 years) following orthotopic heart (HT) and combined heart and lung transplantation (HLT) performed at our 2 institutes between February 1985 and August 1989. Cyclosporin A, azathioprine and steroids were given as routine immunosuppression, whilst anti-th...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01711219
更新日期：1990-01-01 00:00:00
abstract：OBJECTIVE:We tested the hypothesis that synchronization to patient effort during intermittent mandatory ventilation (SIMV), when compared to conventional unsynchronized intermittent mandatory ventilation (IMV), will decrease energy expenditure, as reflected by decreased oxygen consumption (VO2). DESIGN:We used a four-...
journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s001340050359
更新日期：1997-04-01 00:00:00
abstract：:Conventional PEEP ventilation has been recently reported to be deleterious in some cases of ARF with unilateral pneumonia. In such respect, two cases of unilateral bacterial pneumonia were intubated with a Carlens tracheal tube. Measurement of tidal volume, static compliance, and functional residual capacity of each l...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01683935
更新日期：1979-11-01 00:00:00
abstract：PURPOSE:The aim of our study was to analyze changes in the consumption of MRSA-active antibiotics and in the burden of methicillin-resistant S. aureus (MRSA) over a period of 9 years in a network of German intensive care units (ICU). METHODS:Data from 55 ICUs in Germany were analyzed from 2001 through 2009. The term "...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-011-2335-9
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:To determine: (1) the proportion of small (<5 mm) or thrombosed internal jugular veins (IJV) and femoral veins (FV) in which catheter placement would be difficult without ultrasound guidance; (2) which position increases central vein sizes and may facilitate cannulation of these vessels. DESIGN:Prospective s...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-007-0875-9
更新日期：2008-02-01 00:00:00
abstract：:The original version of this article unfortunately contained a mistake. ...
journal_title：Intensive care medicine
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00134-020-06009-2
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:To compare the efficiency of non-invasive positive pressure ventilation (NPPV) in decompensated patients with either chronic obstructive pulmonary disease (COPD) or chronic restrictive pulmonary disease. DESIGN:Retrospective study. SETTING:A 17-bed intensive care unit in a university teaching hospital. SET...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-003-1654-x
更新日期：2003-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the nursing time required for difficult-to-wean patients in a dedicated weaning center (WC) and to examine the correlation of the nursing time with nursing workload (NW) scores and with clinical severity and dependency. SETTING:Four-bed WC of a pulmonary rehabilitation department. INTERVENTION:N...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340051249
更新日期：2000-06-01 00:00:00
abstract：PURPOSE:To assess the impact of lung ultrasound (LU) on clinical decision making in mechanically ventilated critically ill patients. METHODS:One hundred and eighty-nine patients took part in this prospective study. The patients were enrolled in the study when LU was requested by the primary physician for (1) unexplain...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-013-3133-3
更新日期：2014-01-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and safety of intravenous sildenafil for immediate postoperative pulmonary hypertension (PH) in pediatric patients undergoing congenital heart surgery. METHODS:A double-blind, multicenter, placebo-controlled, dose-ranging, parallel-group trial was conducted. Patients were randomized to...
journal_title：Intensive care medicine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00134-010-2065-4
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:To apply the modified pediatric RIFLE criteria for severity of acute kidney injury (AKI) to pediatric burn ICU patients and to evaluate the overall incidence of AKI, risk factors for AKI and influence of AKI on outcome. DESIGN:Retrospective, descriptive cohort study. SETTING:10-bed burn PICU facility. PATI...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-009-1638-6
更新日期：2009-12-01 00:00:00
