In vitro activity of fleroxacin against multiresistant gram-negative bacilli isolated from patients with nosocomial infections.

abstract：OBJECTIVE:To assess the ability of the Clinical Risk Index for Babies (CRIB) to predict long-term neurodevelopmental impairment in very low birth weight (VLBW) infants. DESIGN:Single-center cohort study. SETTING:Tertiary neonatal care hospital and follow-up clinic. PATIENTS:Four hundred fifty-five VLBW infants conse...

journal_title：Intensive care medicine

authors： Bührer C,Grimmer I,Metze B,Obladen M

更新日期：2000-03-01 00:00:00

abstract：PURPOSE:We assessed outcomes in brain-injured patients after implementation of a multi-faceted approach to reduce respiratory complications in intensive care units. METHODS:Prospective nationwide before-after trial. Consecutive adults with acute brain injury requiring mechanical ventilation for ≥24 h in 20 French inte...

journal_title：Intensive care medicine

authors： Asehnoune K,Mrozek S,Perrigault PF,Seguin P,Dahyot-Fizelier C,Lasocki S,Pujol A,Martin M,Chabanne R,Muller L,Hanouz JL,Hammad E,Rozec B,Kerforne T,Ichai C,Cinotti R,Geeraerts T,Elaroussi D,Pelosi P,Jaber S,Dalicha

更新日期：2017-07-01 00:00:00

abstract：:We have treated 30 patients with flail chest, with priority given to associated factors (pain, secretions retention, hemo-/pneumothorax and underlying pulmonary contusion). When this treatment was insufficient IMV + PEEP was instituted; in this group there was a 58.8% incidence of pneumonia, 47.5% of sepsis and 11.7 d...

journal_title：Intensive care medicine

authors： Carpintero JL,Rodriguez Diez A,Ruiz Elvira MJ,Benitez JA,Perez Rielo A

更新日期：1980-08-01 00:00:00

abstract：OBJECTIVE:To assess the effects of intravenous fish oil fat emulsion on the metabolic alterations induced by lipopolysaccharide (LPS) challenge in healthy volunteers. DESIGN:Two groups of eight healthy subjects were randomized to receive either two pharmacological doses of intravenous FO fat emulsion or no treatment. ...

journal_title：Intensive care medicine

authors： Pluess TT,Hayoz D,Berger MM,Tappy L,Revelly JP,Michaeli B,Carpentier YA,Chioléro RL

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:We investigated the effect of different levels of continuous positive airway pressure (CPAP) on the cricothyroid (CT; a tensor muscle of the vocal folds) and posterior cricoarytenoid (PCA; sole abductor muscle of the vocal folds) muscles in dogs. DESIGN:Prospective, controlled animal study. SUBJECTS:Nine m...

journal_title：Intensive care medicine

authors： Iwasaki H,Ohmori H,Sumita S,Yamauchi M,Namiki A

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:The role of haemofiltration as an adjunctive treatment of sepsis remains a contentious issue. To address the role of dose and to explore the biological effects of haemofiltration we compared the effects of standard and high-volume haemofiltration (HVHF) in a peritonitis-induced model of porcine septic shock. ...

journal_title：Intensive care medicine

authors： Sykora R,Chvojka J,Krouzecky A,Radej J,Karvunidis T,Varnerova V,Novak I,Matejovic M

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:To determine the effects of increasing dosages of continuously infused arginine-vasopressin (AVP) on mucosal tissue oxygen tension and oxygen supply in an auto-perfused, innervated jejunal segment in an acute endotoxic porcine model. DESIGN:Prospective, randomized, experimental study. SETTING:University hos...

journal_title：Intensive care medicine

authors： Knotzer H,Maier S,Dünser MW,Hasibeder WR,Hausdorfer H,Brandner J,Torgersen C,Ulmer H,Friesenecker B,Iannetti C,Pajk W

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Approximately 20 years have passed since we reported our results of histologically proven cytomegalovirus (CMV) pneumonia in non-immunocompromised ICU patients. Even if there are more recent reports suggesting that CMV may worsen the outcomes for ICU patients, there is no definite answer to this question: ...

journal_title：Intensive care medicine

authors： Papazian L,Hraiech S,Lehingue S,Roch A,Chiche L,Wiramus S,Forel JM

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To apply the modified pediatric RIFLE criteria for severity of acute kidney injury (AKI) to pediatric burn ICU patients and to evaluate the overall incidence of AKI, risk factors for AKI and influence of AKI on outcome. DESIGN:Retrospective, descriptive cohort study. SETTING:10-bed burn PICU facility. PATI...

journal_title：Intensive care medicine

authors： Palmieri T,Lavrentieva A,Greenhalgh D

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To assess noise exposure during noninvasive ventilation (NIV) with different types of interface (helmet, nasal, and facial masks). SUBJECTS AND METHODS:Ten "naive" healthy volunteers underwent NIV at pressure support levels of 10 and 15 cmH2O with: (a) helmet, (b) helmet equipped with HME filters at the junc...

journal_title：Intensive care medicine

authors： Cavaliere F,Conti G,Costa R,Proietti R,Sciuto A,Masieri S

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To investigate the accuracy of eight different prognostic scores (Stiehm, Niklasson, Leclerc, Garlund, the MOC score, Tesero, the Glasgow Meningococcal Septicaemia Prognostic Score (GMSPS) and Tüyzüs) in the prediction of fatal outcome in meningococcal disease. DESIGN:Combined prospective and retrospective s...

journal_title：Intensive care medicine

authors： Derkx HH,van den Hoek J,Redekop WK,Bijlmer RP,van Deventer SJ,Bossuyt PM

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:Measurement of functional residual capacity (FRC) during mechanical ventilation is important to standardise respiratory system compliance and adjust the ventilator settings to optimise lung recruitment. In the present study we compared three methods to measure FRC. DESIGN:The bias flow nitrogen washout techn...

journal_title：Intensive care medicine

authors： Schibler A,Hammer J,Isler R,Buess C,Newth CJ

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:A readily available assessment of changes in pleural pressure would be useful for ventilator and fluid management in critically ill patients. We examined whether changes in pulmonary artery occlusion pressure (Ppao) adequately reflect respiratory changes in pleural pressure as assessed by changes in intraesop...

journal_title：Intensive care medicine

authors： Bellemare P,Goldberg P,Magder SA

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To determine what change in respiratory function occurred following prolonged and efficient continuous arteriovenous haemofiltration (CAVH) in a group of patients with multiple organ systems failure (MOSF). DESIGN:A retrospective assessment using patient notes and ICU charts. SETTING:The Intensive Care Unit...

journal_title：Intensive care medicine

authors： Bagshaw ON,Anaes FR,Hutchinson A

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:Sedatives administered to critically ill children should be titrated to effect, because both under- and oversedation may have negative effects. We conducted a systematic review to examine reported incidences of under-, optimal, and oversedation in critically ill children receiving intensive care. METHODS:A sys...

journal_title：Intensive care medicine

authors： Vet NJ,Ista E,de Wildt SN,van Dijk M,Tibboel D,de Hoog M

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:The clinical significance of septic myocardial dysfunction is controversial, a fact that may be explained by the influence of loading conditions. Many indices may be useful to characterize cardiac function during septic shock, but their feasibility and physiological coherence in the clinical setting are unknown...

journal_title：Intensive care medicine

authors： Boissier F,Razazi K,Seemann A,Bedet A,Thille AW,de Prost N,Lim P,Brun-Buisson C,Mekontso Dessap A

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence and the prognostic significance of microalbuminuria in patients after aneurysmal subarachnoid hemorrhage (SAH). DESIGN:Prospective and observational clinical study. SETTING:Multidisciplinary intensive care unit. PATIENTS:Fifty-one consecutive patients who underwent aneurysm clip...

journal_title：Intensive care medicine

authors： Terao Y,Takada M,Tanabe T,Ando Y,Fukusaki M,Sumikawa K

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:Evaluating the prevalence, risk factors and prevention of pressure ulcers in Dutch intensive care units (ICUs). DESIGN:Cross-sectional design. SETTING:ICUs of acute care hospitals that participated in the 1998 and 1999 national prevalence surveys. Data were collected on 1 day in each year. PATIENTS:Eight h...

journal_title：Intensive care medicine

authors： Bours GJ,De Laat E,Halfens RJ,Lubbers M

更新日期：2001-10-01 00:00:00

abstract：:Values obtained for cardiac output (CO) were compared using thermodilution (TD) with those obtained using bioimpedance (Bi) as measured using the Bomed NCCOM3 (Revision 6) in 28 consecutive patients in the first 24 h after coronary artery bypass surgery (CABS). In 46 paired measurements made in the first 12 h after CA...

journal_title：Intensive care medicine

authors： Thomas AN,Ryan J,Doran BR,Pollard BJ

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To present our observation of the development of a rare nail deformity in the prolonged course of disease of a critically ill patient with a pulmonary abscess. DESIGN:Case report. SETTING:Tertiary referral, 16-bed, level I surgical ICU in an academic hospital. PATIENT:A 48-year-old Caucasian male was treat...

journal_title：Intensive care medicine

authors： Wester JP,van Eps RS,Stouthamer A,Girbes AR

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To describe a real-time ultrasound sign, the visualization of the cavity and the walls of the maxillary sinus ("sinusogram"), and to assess its correlation with total opacity of the sinus. DESIGN:Prospective clinical study. SETTING:The medical ICU of a university-affiliated hospital. PATIENTS:The significa...

journal_title：Intensive care medicine

authors： Lichtenstein D,Biderman P,Mezière G,Gepner A

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:To evaluate various treatment strategies in critically ill patients with ischaemic acute renal failure, there is a need for reliable bedside measurements of total renal blood flow (RBF), glomerular filtration rate (GFR) and renal oxygen consumption without the need for urine collection. DESIGN:The continuous...

journal_title：Intensive care medicine

authors： Swärd K,Valsson F,Sellgren J,Ricksten SE

更新日期：2004-09-01 00:00:00

abstract：PURPOSE:To develop a liver function-related risk prediction tool to identify acute-on-chronic liver failure patients at greatest risk of in-hospital mortality. METHODS:The LiFe (liver, injury, failure, evaluation) score, was constructed based on the opinions of 157 intensivists within the European Society for Intensiv...

journal_title：Intensive care medicine

authors： Edmark C,McPhail MJW,Bell M,Whitehouse T,Wendon J,Christopher KB

更新日期：2016-03-01 00:00:00

abstract：:The reliability of cardiac output estimation by thermodilution during artificial ventilation was studied in anesthetized pigs at the right side of the heart. The estimates exhibited a cyclic modulation related to the ventilation. The amplitude of the modulation was independent of the level of positive end-expiratory p...

journal_title：Intensive care medicine

authors： Jansen JR,Versprille A

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:Septic shock-induced disseminated intravascular coagulopathy (DIC) contributes to multiple organ failure. Mechanisms governing vascular responses to open occurrence of DIC have not yet been established. Circulating plasma microparticles (MPs), released upon cell stress, constitute a catalytic procoagulant surfa...

journal_title：Intensive care medicine

authors： Delabranche X,Boisramé-Helms J,Asfar P,Berger A,Mootien Y,Lavigne T,Grunebaum L,Lanza F,Gachet C,Freyssinet JM,Toti F,Meziani F

更新日期：2013-10-01 00:00:00

abstract：:The case of an 11-year-old boy who suffered second and third degree burns to 78% of his body is reported. The large doses of morphine used as analgesia resulted in severe side effects: ventilatory dependence, impairment of gastrointestinal function and psychological disturbance. Intravenous lignocaine was added withou...

journal_title：Intensive care medicine

authors： Lyons B,Casey W,Doherty P,McHugh M,Moore KP

更新日期：1996-03-01 00:00:00

abstract：PURPOSE:Indications and optimal timing for tracheostomy in traumatic brain-injured (TBI) patients are uncertain. This study aims to describe the patients' characteristics, timing, and factors related to the decision to perform a tracheostomy and differences in strategies among different countries and assess the effect ...

journal_title：Intensive care medicine

authors： Robba C,Galimberti S,Graziano F,Wiegers EJA,Lingsma HF,Iaquaniello C,Stocchetti N,Menon D,Citerio G,CENTER-TBI ICU Participants and Investigators.

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:To obtain insight into the occurrence of brain death and the potential for brain dead and controlled non-heart-beating organ donors (CNHB) in patients with traumatic brain injury (TBI), subarachnoid haemorrhage (SAH) and intracerebral haemorrhage (ICH) in a large neurosurgical serving area (2.1 million inhabi...

journal_title：Intensive care medicine

authors： Kompanje EJO,Bakker J,Slieker FJA,IJzermans JNM,Maas AIR

更新日期：2006-02-01 00:00:00

abstract：PURPOSE:Mechanical ventilation with lower tidal volumes (≤6 ml/kg of predicted body weight, PBW) could benefit patients without acute respiratory distress syndrome (ARDS). However, tidal volume reduction could be associated with increased patient discomfort and sedation needs, and consequent longer duration of ventilat...

journal_title：Intensive care medicine

authors： Serpa Neto A,Simonis FD,Barbas CS,Biehl M,Determann RM,Elmer J,Friedman G,Gajic O,Goldstein JN,Horn J,Juffermans NP,Linko R,de Oliveira RP,Sundar S,Talmor D,Wolthuis EK,de Abreu MG,Pelosi P,Schultz MJ

更新日期：2014-07-01 00:00:00

abstract：PURPOSE:Septic shock induces a decrease in dendritic cells (DCs) that may contribute to sepsis-induced immunosuppression. We analyzed the time course of circulating DCs in patients with septic shock and its relation to susceptibility to intensive care unit (ICU)-acquired infections. METHODS:We enrolled adult patients ...

journal_title：Intensive care medicine

authors： Grimaldi D,Louis S,Pène F,Sirgo G,Rousseau C,Claessens YE,Vimeux L,Cariou A,Mira JP,Hosmalin A,Chiche JD

更新日期：2011-09-01 00:00:00