The epidemiology of infections in intensive care units.

abstract：:The influence of varying cardiac output (CO) on thermal-dye extravascular lung water (EVLW) was investigated in a total of 40 cardiac surgery patients before the onset of the operation. EVLW was measured by means of the double indicator dilution technique with indocyanine green as the non-diffusible indicator and a mi...

journal_title：Intensive care medicine

authors： Boldt J,Kling D,von Bormann B,Scheld HH,Hempelmann G

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:We perform an ethical analysis of European Union Directive 2001/20/EC on the simplification and harmonization of guidelines regarding good clinical practice in the conduct of clinical trials involving drugs. BACKGROUND:The Directive provides guidance on protecting incapacitated subjects who participate in dr...

journal_title：Intensive care medicine

authors： Silverman HJ,Druml C,Lemaire F,Nelson R,European Union Directive.

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To determine if the plasma levels of three endothelial-specific proteins, von Willebrand factor (vWF), tissue factor pathway inhibitor (TFPI) and thrombomodulin (TM) may be useful in predicting the development of acute respiratory distress syndrome (ARDS). DESIGN:Blood samples were obtained from normal healt...

journal_title：Intensive care medicine

authors： Bajaj MS,Tricomi SM

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:Computerized clinical decision support systems (CDSS) for intensive insulin therapy (IIT) generate recommendations using blood glucose (BG) values manually transcribed from testing devices to computers, a potential source of error. We quantified the frequency and effect of blood glucose transcription mismatches...

journal_title：Intensive care medicine

authors： Campion TR Jr,May AK,Waitman LR,Ozdas A,Gadd CS

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To provide evidence for the upregulation of endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS) in the assumed imbalance in the pathophysiology of rapid progressive pulmonary hypertension of the newborn (RPPHN), which is characterized by abnormal hypertrophy of the pulmonary art...

journal_title：Intensive care medicine

authors： Hoehn T,Preston AA,McPhaden AR,Stiller B,Vogel M,Bührer C,Wadsworth RM

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Aspiration of dead space (ASPIDS) improves carbon dioxide (CO2) elimination by replacing dead space air rich in CO2 with fresh gas during expiration. The hypothesis was that ASPIDS allows normocapnia to be maintained at low tidal volumes (VT). DESIGN:Prospective study. SETTING:Adult intensive care unit in a...

journal_title：Intensive care medicine

authors： De Robertis E,Servillo G,Jonson B,Tufano R

更新日期：1999-07-01 00:00:00

abstract：PURPOSE:Hypoxic hepatitis (HH) is a form of hepatic injury following arterial hypoxemia, ischemia, and passive congestion of the liver. We investigated the incidence and the prognostic implications of HH in the medical intensive care unit (ICU). METHODS:A total of 1,066 consecutive ICU admissions at three medical ICUs...

journal_title：Intensive care medicine

authors： Fuhrmann V,Kneidinger N,Herkner H,Heinz G,Nikfardjam M,Bojic A,Schellongowski P,Angermayr B,Schöniger-Hekele M,Madl C,Schenk P

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:The Guillain-Barré syndrome (GBS) is an acute inflammatory polyneuropathy related to autoimmunity. However, no conclusive etiological concept has yet been found. We examined the variation in autoantibodies to lipids in serum of GBS patients in response to the course of the disease but investigated titer modif...

journal_title：Intensive care medicine

authors： Nakos G,Tziakou E,Maneta-Peyret L,Nassis C,Lekka ME

更新日期：2005-10-01 00:00:00

abstract：PURPOSE:Relatives of intensive care unit (ICU) patients suffer emotional distress that impairs their ability to acquire the information they need from the staff. We sought to evaluate whether providing relatives with a list of important questions was associated with better comprehension on day 5. METHODS:Randomized, p...

journal_title：Intensive care medicine

authors： Azoulay E,Forel JM,Vinatier I,Truillet R,Renault A,Valade S,Jaber S,Durand-Gasselin J,Schwebel C,Georges H,Merceron S,Cariou A,Moussa M,Hraiech S,Argaud L,Leone M,Curtis JR,Kentish-Barnes N,Jouve E,Papazian L

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:To determine the oxygen affinity for optimal tissue oxygen delivery with a hemoglobin-hydroxyethyl starch conjugate (HRC 101). METHODS:Anesthetized rats were hemodiluted (180 ml kg(-1)) with low (P(50) approximately 70 mmHg) or high affinity (P(50) approximately 14 mmHg) HRC 101 at hemoglobin (Hb) concentratio...

journal_title：Intensive care medicine

authors： Hare GM,Liu E,Baker AJ,Mazer CD

更新日期：2009-11-01 00:00:00

abstract：:We have treated 30 patients with flail chest, with priority given to associated factors (pain, secretions retention, hemo-/pneumothorax and underlying pulmonary contusion). When this treatment was insufficient IMV + PEEP was instituted; in this group there was a 58.8% incidence of pneumonia, 47.5% of sepsis and 11.7 d...

journal_title：Intensive care medicine

authors： Carpintero JL,Rodriguez Diez A,Ruiz Elvira MJ,Benitez JA,Perez Rielo A

更新日期：1980-08-01 00:00:00

abstract：:We compare two patients admitted after near drowning. Both presented a severe metabolic acidosis, but only one of them developed an acute pulmonary edema with hypoxemia. An increase of lipid peroxides associated with a reduction of vitamin E concentration has been observed in this later patient. Lipid peroxidation, on...

journal_title：Intensive care medicine

authors： Bertrand Y,Artoisenet A,Allard B,Barbier B,de Meulder A,Raynaert M,Mathieu P,Dumont E

更新日期：1985-01-01 00:00:00

abstract：:Peritoneal dialysis was used in experimental lactic acidosis caused by hypoxia for the removal of endogenous lactate. Two types of dialysis fluid, with and without vasodilator sodium nitroprusside, added intraperitoneally were used. The addition of sodium nitroprusside increased peritoneal the clearance of lactate as ...

journal_title：Intensive care medicine

authors： Breborowicz A,Szulc R

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of traditional and online teaching methods for educating anesthesiology residents in the principles and practice of difficult airway management. DESIGN:Prospective, randomized, controlled trial. SETTING:University hospital. PARTICIPANTS:Two randomly selected groups, each contai...

journal_title：Intensive care medicine

authors： Bello G,Pennisi MA,Maviglia R,Maggiore SM,Bocci MG,Montini L,Antonelli M

更新日期：2005-04-01 00:00:00

abstract：PURPOSE:To describe the course of early organ dysfunction in a cohort of patients admitted in ICU suffering classic heatstroke. METHODS:Prospective observational single-centre cohort study with a 1-year follow-up. INTERVENTIONS:None. MEASUREMENTS AND MAIN RESULTS:Clinical and biological data of 22 patients were anal...

journal_title：Intensive care medicine

authors： Pease S,Bouadma L,Kermarrec N,Schortgen F,Régnier B,Wolff M

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence of relative adrenal insufficiency in patients successfully resuscitated after cardiac arrest, and its prognostic role in post-resuscitation disease. DESIGN AND SETTING:A prospective observational single-center study in a medical intensive care unit. PATIENTS:64 patients hospitalised...

journal_title：Intensive care medicine

authors： Pene F,Hyvernat H,Mallet V,Cariou A,Carli P,Spaulding C,Dugue MA,Mira JP

更新日期：2005-05-01 00:00:00

abstract：:Two hundred and seventy-three acute hemorrhagic shocks were treated in 1984 in a pre-hospital emergency care unit. Twenty patients (7%) had a paradoxical bradycardia: they were conscious, 9 of them had an undetectable systolic arterial pressure with the sphygmomanometric method but the femoral pulse was still present....

journal_title：Intensive care medicine

authors： Barriot P,Riou B

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:To analyze the effects of polymyxin B-immobilized fiber (PMX-F) on bone resorption in septic patients. DESIGN AND SETTING:Observational prospective study in intensive care units of a general hospital. PATIENTS AND PARTICIPANTS:25 patients with severe sepsis and 20 healthy controls. MEASUREMENTS AND RESULTS...

journal_title：Intensive care medicine

authors： Nakamura T,Kawagoe Y,Matsuda T,Koide H

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To assess the effect of partial liquid ventilation with perfluorocarbons on hemodynamics and gas exchange in large pigs with induced acute lung injury (ALI). DESIGN:Randomized, prospective, double-control, experimental study. Experimental intensive care unit of a university. MATERIALS:Eighteen large pigs (5...

journal_title：Intensive care medicine

authors： Houmes RJ,Verbrugge SJ,Hendrik ER,Lachmann B

更新日期：1995-12-01 00:00:00

abstract：PURPOSE:To establish the baseline prescribing error rate in a tertiary paediatric intensive care unit (PICU) and to determine the impact of a zero tolerance prescribing (ZTP) policy incorporating a dedicated prescribing area and daily feedback of prescribing errors. METHODS:A prospective, non-blinded, observational st...

journal_title：Intensive care medicine

authors： Booth R,Sturgess E,Taberner-Stokes A,Peters M

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Atracurium besylate and laudanosine cause excitement and seizures when introduced into the central nervous system of laboratory animals. We examined the modulation of lipid-protein interaction in the lipid environment of rat brain synaptosomal plasma membrane (SPM)-bound enzymes as a possible mechanism leadin...

journal_title：Intensive care medicine

authors： Kamper EF,Siafaka J,Stavridis J

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:To validate a simple method avoiding discard volumes in pediatric patients with indwelling arterial and venous lines. DESIGN:Zero-discarding was achieved by passive extracorporeal arteriovenous backflow via standard single pressure transducer equipment. We tested backflow distances (10, 20 and 30 cm beyond t...

journal_title：Intensive care medicine

authors： Weiss M,Fischer J,Boeckmann M,Rohrer B,Baenziger O

更新日期：2001-06-01 00:00:00

abstract：:This article was originally published under a CC BY-NC 4.0 license, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the paper have been modified accordingly. ...

journal_title：Intensive care medicine

authors： Harris S,Singer M,Sanderson C,Grieve R,Harrison D,Rowan K

更新日期：2018-05-01 00:00:00

abstract：:A case of aspiration pneumonitis during Caesarean section is described. The patient was treated with high-level continuous positive airway pressure (CPAP) resulting in marked improvement and discharge from the Intensive Care Unit 44 hours after the aspiration had occurred. ...

journal_title：Intensive care medicine

authors： Bar ZG,Sternberg N,Laufer N,Katzenelson R,Cotev S

更新日期：1980-05-01 00:00:00

abstract：OBJECTIVE:The objective was to identify factors associated with thrombocytopenia and to assess to what extent thrombocytopenia increases bleeding complications in liver transplant patients. DESIGN:Retrospective study. SETTING:Surgical intensive care unit in a university hospital. PATIENTS:One hundred and sixty-one p...

journal_title：Intensive care medicine

authors： Ben Hamida C,Lauzet JY,Rézaiguia-Delclaux S,Duvoux C,Cherqui D,Duvaldestin P,Stéphan F

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:Invasive candidiasis (IC) outcomes in intensive care units (ICUs) could be improved by the early administration of antifungals. The Candida Score (CS) prediction rule has been proposed for the selection of patients who could develop IC. Procalcitonin (PCT) levels allow prompt identification of sepsis, but the...

journal_title：Intensive care medicine

authors： Charles PE,Castro C,Ruiz-Santana S,León C,Saavedra P,Martín E

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To investigate plasma high-mobility group box 1 protein (HMGB1) concentration and its relationship with organ dysfunction and outcome in septic shock patients. DESIGN AND SETTING:Prospective, noninterventional study. Medical adult intensive care unit at a university hospital in France. PATIENTS:42 criticall...

journal_title：Intensive care medicine

authors： Gibot S,Massin F,Cravoisy A,Barraud D,Nace L,Levy B,Bollaert PE

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:Real-time measurement of stroke volume variation by arterial pulse contour analysis (SVV) is useful in predicting volume responsiveness and monitoring volume therapy in mechanically ventilated patients. This study investigated the influence of the depth of tidal volume (V(t)) on SVV both during the state of f...

journal_title：Intensive care medicine

authors： Reuter DA,Bayerlein J,Goepfert MS,Weis FC,Kilger E,Lamm P,Goetz AE

更新日期：2003-03-01 00:00:00

abstract：:We describe a case of the dialysis disequilibrium syndrome (DDS) that was marked by the rapid onset of cerebral edema and the subsequent development of acute respiratory failure. The patient was treated successfully with a combination of mechanical hyperventilation and mannitol. The clinical presentation, pathogenesis...

journal_title：Intensive care medicine

authors： DiFresco V,Landman M,Jaber BL,White AC

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of respiratory physiotherapy on the prevention and treatment of ventilator-associated pneumonia (VAP) for adults in an intensive care unit (ICU) with an acquired brain injury (ABI). DESIGN AND SETTING:Two-part, prospective, randomised controlled trial. PATIENTS:A total of 144 subje...

journal_title：Intensive care medicine

authors： Patman S,Jenkins S,Stiller K

更新日期：2009-02-01 00:00:00