Removal of endogenous lactates via the peritoneum in experimental lactic acidosis.

abstract：OBJECTIVE:We describe a patient with a prolonged and severe hypercapnia occurring during an episode of status asthmaticus induced by ophthalmic instillation of carteolol. SETTING:Prehospital Emergency Medical Service and Pulmonary Intensive Care Unit in a university hospital. PATIENT:A 35-year-old female developed an...

journal_title：Intensive care medicine

authors： Adnet F,Plaisance P,Borron SW,Levy A,Payen D

更新日期：1998-12-01 00:00:00

abstract：PURPOSE:The clinical significance of septic myocardial dysfunction is controversial, a fact that may be explained by the influence of loading conditions. Many indices may be useful to characterize cardiac function during septic shock, but their feasibility and physiological coherence in the clinical setting are unknown...

journal_title：Intensive care medicine

authors： Boissier F,Razazi K,Seemann A,Bedet A,Thille AW,de Prost N,Lim P,Brun-Buisson C,Mekontso Dessap A

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:Early central venous catheter (CVC) insertion in Ebola virus disease (EVD) is a novel approach and has not previously been described. This report delineates the safety, feasibility and clinical implications of early CVC insertion as the optimum means of vascular access in patients with EVD, in the setting of a ...

journal_title：Intensive care medicine

authors： Rees PS,Lamb LE,Nicholson-Roberts TC,Ardley CN,Bailey MS,Hinsley DE,Fletcher TE,Dickson SJ

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:To assess the reproducibility of respiratory dead space measurements in ventilated children. DESIGN:Prospective study. SETTING:University pediatric intensive care unit. PATIENTS:Thirty-two mechanically ventilated children (0.13-15.4 years) who were clinically stable. METHODS:The single-breath CO(2) test ...

journal_title：Intensive care medicine

authors： Riou Y,Leclerc F,Neve V,Dupuy L,Noizet O,Leteurtre S,Sadik A

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:Venous thromboembolism (VTE) is a common but often overlooked life-threatening complication of critical illness. The aim of this cross-sectional survey was to assess current practice of thromboprophylaxis as well as adherence to international guidelines. METHODS:After ethics committee approval, all intensive c...

journal_title：Intensive care medicine

authors： Schaden E,Metnitz PG,Pfanner G,Heil S,Pernerstorfer T,Perger P,Schoechl H,Fries D,Guetl M,Kozek-Langenecker S

更新日期：2012-06-01 00:00:00

abstract：:This article was originally published under a CC BY-NC 4.0 license, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the paper have been modified accordingly. ...

journal_title：Intensive care medicine

authors： Harris S,Singer M,Sanderson C,Grieve R,Harrison D,Rowan K

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:A prospective physiological study was performed in 12 paediatric patients with acute moderate hypercapnic respiratory insufficiency to assess the ability of noninvasive positive pressure ventilation (NPPV) to unload the respiratory muscles and improve gas exchange. MATERIALS AND METHODS:Breathing pattern,...

journal_title：Intensive care medicine

authors： Essouri S,Durand P,Chevret L,Haas V,Perot C,Clement A,Devictor D,Fauroux B

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:Sepsis is a major health burden worldwide. Preclinical investigations in animals and retrospective studies in patients have suggested that inhibition of platelets may improve the outcome of sepsis. In this study we investigated whether chronic antiplatelet therapy impacts on the presentation and outcome of seps...

journal_title：Intensive care medicine

authors： Wiewel MA,de Stoppelaar SF,van Vught LA,Frencken JF,Hoogendijk AJ,Klein Klouwenberg PMC,Horn J,Bonten MJ,Zwinderman AH,Cremer OL,Schultz MJ,van der Poll T,MARS Consortium.

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:Our study aimed to determine the efficacy and safety of colistin in the treatment of ventilator-associated pneumonia (VAP) caused by pan-drug-resistant Pseudomonas aeruginosa or Acinetobacter baumanii. DESIGN:Pairwise, retrospective exposed-unexposed study. SETTING:Combined medical and surgical intensive ca...

journal_title：Intensive care medicine

authors： Kallel H,Hergafi L,Bahloul M,Hakim A,Dammak H,Chelly H,Hamida CB,Chaari A,Rekik N,Bouaziz M

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:We propose that higher airway occlusion pressure (P0.1) responses to hypercapnic challenge (HC) indicate less severe injury. The study aim was to determine whether P0.1 responses to HC were associated with successful weaning after prolonged mechanical ventilation (PMV) in patients with brainstem lesions and t...

journal_title：Intensive care medicine

authors： Wu YK,Lee CH,Shia BC,Tsai YH,Tsao TC

更新日期：2009-01-01 00:00:00

abstract：:A 46-year-old man was diagnosed clinically brain dead after sustaining head trauma. The patient was in deep coma, brain nerves were unresponsive and spontaneous breathing was absent. However, EEG showed well preserved activity, but no reactivity to external stimuli. EEG activity disappeared within 40 h. BAEP were high...

journal_title：Intensive care medicine

authors： Kaukinen S,Mäkelä K,Häkkinen VK,Martikainen K

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:To determine if the plasma levels of three endothelial-specific proteins, von Willebrand factor (vWF), tissue factor pathway inhibitor (TFPI) and thrombomodulin (TM) may be useful in predicting the development of acute respiratory distress syndrome (ARDS). DESIGN:Blood samples were obtained from normal healt...

journal_title：Intensive care medicine

authors： Bajaj MS,Tricomi SM

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:Mechanical ventilation with lower tidal volumes (≤6 ml/kg of predicted body weight, PBW) could benefit patients without acute respiratory distress syndrome (ARDS). However, tidal volume reduction could be associated with increased patient discomfort and sedation needs, and consequent longer duration of ventilat...

journal_title：Intensive care medicine

authors： Serpa Neto A,Simonis FD,Barbas CS,Biehl M,Determann RM,Elmer J,Friedman G,Gajic O,Goldstein JN,Horn J,Juffermans NP,Linko R,de Oliveira RP,Sundar S,Talmor D,Wolthuis EK,de Abreu MG,Pelosi P,Schultz MJ

更新日期：2014-07-01 00:00:00

abstract：PURPOSE:To assess the effects of alveolar recruitment maneuvers (ARMs) on clinical outcomes in patients with acute respiratory distress syndrome (ARDS). METHODS:We conducted a search of the MEDLINE, EMBASE, LILACS, CINAHL, CENTRAL, Scopus, and Web of Science (from inception to July 2014) databases for all (i.e. no lan...

journal_title：Intensive care medicine

authors： Suzumura EA,Figueiró M,Normilio-Silva K,Laranjeira L,Oliveira C,Buehler AM,Bugano D,Passos Amato MB,Ribeiro Carvalho CR,Berwanger O,Cavalcanti AB

更新日期：2014-09-01 00:00:00

abstract：:In critically ill patients, it is frequently challenging to identify who will benefit from admission to the intensive care unit and life-sustaining interventions when the chances of a meaningful outcome are unclear. In addition, the acute illness not only affects the patients but also family members or surrogates who ...

journal_title：Intensive care medicine

authors： Vink EE,Azoulay E,Caplan A,Kompanje EJO,Bakker J

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:To provide evidence for the upregulation of endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS) in the assumed imbalance in the pathophysiology of rapid progressive pulmonary hypertension of the newborn (RPPHN), which is characterized by abnormal hypertrophy of the pulmonary art...

journal_title：Intensive care medicine

authors： Hoehn T,Preston AA,McPhaden AR,Stiller B,Vogel M,Bührer C,Wadsworth RM

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Evaluation of the distribution and antibiotic susceptibility of the aerobic gram-negative bacilli (AGNB) isolated from patients in intensive care units (ICU study). DESIGN AND SETTING:Microbiological study carried out in 1991 in 39 teaching hospitals. A standardized method was used to determine the minimum i...

journal_title：Intensive care medicine

authors： Jarlier V,Fosse T,Philippon A

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:Antipyrine metabolism is a "gold standard" measure of mixed cytochrome P450 (CYP) mediated drug metabolism in humans. Cytokines (e.g., interleukin-6) and nitric oxide reduce CYP 450 activity in vitro and in vivo. Because interleukin-6 and nitric oxide production increases in children with sepsis-induced multi...

journal_title：Intensive care medicine

authors： Carcillo JA,Doughty L,Kofos D,Frye RF,Kaplan SS,Sasser H,Burckart GJ

更新日期：2003-06-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Baedorf Kassis E,Train S,MacNeil B,Loring SH,Talmor D

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the influence of changes in alveolar ventilation on the following tonometry-derived variables: gastric intramucosal CO2 tension (PtCO2), gastric arterial CO2 tension difference (PgapCO2), gastric intramucosal pH (pHi) and arterial pH-pHi difference (pHgap). DESIGN:Clinical prospective study. SET...

journal_title：Intensive care medicine

authors： Bernardin G,Lucas P,Hyvernat H,Deloffre P,Mattéi M

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:To determine whether erythromycin is non-inferior to metoclopramide in facilitating post-pyloric placement of self-propelled spiral nasoenteric tubes (NETs) in critically ill patients. METHODS:A prospective, multicenter, open-label, parallel, and non-inferiority randomized controlled trial was conducted compar...

journal_title：Intensive care medicine

authors： Hu B,Ouyang X,Lei L,Sun C,Chi R,Guo J,Guo W,Zhang Y,Li Y,Huang D,Sun H,Nie Z,Yu J,Zhou Y,Wang H,Zhang J,Chen C

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:The efficacy of interferon gamma therapy in reducing infection and improving outcome from infection in patients sustaining major injury was examined. DESIGN:Randomized double-blind placebo control trial SETTING:Nine level one university affiliated trauma centers in the United States. PATIENTS AND PARTICIPA...

journal_title：Intensive care medicine

authors： Dries DJ

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:Inhalation of high concentrations of nitric oxide (NO) has been shown to improve gas exchange and to reduce pulmonary vascular resistance in individuals with ischemia-reperfusion injury following orthotopic lung transplantation. We assessed the cardiopulmonary effects of low doses of NO in early allograft dys...

journal_title：Intensive care medicine

authors： Kemming GI,Merkel MJ,Schallerer A,Habler OP,Kleen MS,Haller M,Briegel J,Vogelmeier C,Fürst H,Reichart B,Zwissler B

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To clarify the risk of secondary exposure of medical staff to sarin vapor in the emergency room, and to warn emergency room staffs of the hazard. DESIGN:Retrospective observational survey. SETTING:Emergency department of a university hospital in a metropolitan area of Japan. PARTICIPANTS:Fifteen doctors tr...

journal_title：Intensive care medicine

authors： Nozaki H,Hori S,Shinozawa Y,Fujishima S,Takuma K,Sagoh M,Kimura H,Ohki T,Suzuki M,Aikawa N

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:Lung injury is a severe complication of acute pancreatitis that increases the mortality rate of the disease. The pathophysiology of acute pancreatitis has been studied in several experimental models, but the kinetics of pulmonary complications in relation to the pancreatic disease is not completely understood...

journal_title：Intensive care medicine

authors： Morel DR,Frossard JL,Cikirikcioglu B,Tapponnier M,Pastor CM

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To compare the total plasma cortisol values obtained from three widely used immunoassays and a high pressure liquid chromatography (HPLC) technique on samples obtained from patients with sepsis. DESIGN AND SETTING:Observational interventional in the general intensive care unit of a metropolitan hospital PAT...

journal_title：Intensive care medicine

authors： Cohen J,Ward G,Prins J,Jones M,Venkatesh B

更新日期：2006-11-01 00:00:00

abstract：:The effects of 142 intravenous boluses of althesin (0.05 ml/kg) on cerebral perfusion pressure (CPP) were studied in twelve head injured comatose patients. The data were divided into those where the mean pre-bolus intracranial pressure (ICP) was above or below 20 mmHg and then subdivided into those where the minimum p...

journal_title：Intensive care medicine

authors： Procaccio F,Bingham RM,Hinds CJ,Prior PF

更新日期：1988-01-01 00:00:00

abstract：:The effect of enteral feeding on O2-consumption (VO2) and CO2-production (VCO2) was studied in 9 ventilator-dependent patients, who were in a stable condition without signs of hypermetabolism. Resting energy expenditure (REE) in postabsorptive state was assessed and enteral feeding was started by continuous drip (480 ...

journal_title：Intensive care medicine

authors： van den Berg B,Stam H

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To examine the phenomenon of inappropriate triggering caused by an in-line suction catheter. DESIGN:We used a test lung to assess inappropriate triggering in four ventilators with both pressure and flow triggering. RESULTS:With pressure triggering, inappropriate triggering occurred only in the presence of P...

journal_title：Intensive care medicine

authors： Al-Khafaji A,Manning HL

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:Comparison of side effects (fever shivering and/or allergic reactions, collapse, symptomatic hypocalcaemia) of the different substitution fluids used during therapeutical plasmapheresis. DESIGN:Multicentric retrospective comparative study designed to explore the side effects due to the replacements fluids (a...

journal_title：Intensive care medicine

authors： Korach JM,Berger P,Giraud C,Le Perff-Desman C,Chillet P

更新日期：1998-05-01 00:00:00