当前位置： SCI文献检索 > INTENSIVE CARE MEDICINE期刊下所有文献 > Physiological effects of noninvasive positive ventilation during acute moderate hypercapnic respiratory insufficiency in children.

Physiological effects of noninvasive positive ventilation during acute moderate hypercapnic respiratory insufficiency in children.

Abstract：

INTRODUCTION:A prospective physiological study was performed in 12 paediatric patients with acute moderate hypercapnic respiratory insufficiency to assess the ability of noninvasive positive pressure ventilation (NPPV) to unload the respiratory muscles and improve gas exchange. MATERIALS AND METHODS:Breathing pattern, gas exchange, and inspiratory muscle effort were measured during spontaneous breathing and NPPV. RESULTS:NPPV was associated with a significant improvement in breathing pattern, gas exchange and respiratory muscle output. Tidal volume and minute ventilation increased by 33 and 17%, and oesophageal and diaphragmatic pressure time product decreased by 49 and 56%, respectively. This improvement in alveolar ventilation translated into a reduction in mean partial pressure in carbon dioxide from 48 to 40 mmHg (P = 0.01) and in respiratory rate from 48 to 41 breaths/min (P = 0.01). No difference between a clinical setting and a physiological setting of NPPV was observed. In conclusion, this study shows that NPPV is able to unload the respiratory muscles and improve clinical outcome in young patients admitted to the paediatric intensive care unit for acute moderate hypercapnic respiratory insufficiency.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Essouri S,Durand P,Chevret L,Haas V,Perot C,Clement A,Devictor D,Fauroux B

doi

10.1007/s00134-008-1202-9

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

2248-55

issue

12

eissn

0342-4642

issn

1432-1238

journal_volume

34

pub_type

临床试验,杂志文章

相关文献

INTENSIVE CARE MEDICINE文献大全
  • Effect of severe thrombocytopenia on patient outcome after liver transplantation.

    abstract：OBJECTIVE:The objective was to identify factors associated with thrombocytopenia and to assess to what extent thrombocytopenia increases bleeding complications in liver transplant patients. DESIGN:Retrospective study. SETTING:Surgical intensive care unit in a university hospital. PATIENTS:One hundred and sixty-one p...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-003-1727-x

    authors： Ben Hamida C,Lauzet JY,Rézaiguia-Delclaux S,Duvoux C,Cherqui D,Duvaldestin P,Stéphan F

    更新日期：2003-05-01 00:00:00

  • Continuous arteriovenous haemofiltration and respiratory function in multiple organ systems failure.

    abstract：OBJECTIVE:To determine what change in respiratory function occurred following prolonged and efficient continuous arteriovenous haemofiltration (CAVH) in a group of patients with multiple organ systems failure (MOSF). DESIGN:A retrospective assessment using patient notes and ICU charts. SETTING:The Intensive Care Unit...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01694361

    authors： Bagshaw ON,Anaes FR,Hutchinson A

    更新日期：1992-01-01 00:00:00

  • Study of right ventricular function in ischaemic heart disease using radionuclide angiocardiography.

    abstract：:A technique for the estimation of LVEF from first passage radionuclide angiocardiography was adapted to provide estimates of RVEF. In 17 subjects with no history of cardiovascular disease mean LVEF was 0.71 +/- 0.08 and mean RVEF 0.65 +/- 0.08. Mean values for 15 subjects with coronary artery disease but no previous h...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01683193

    authors： Walton S,Rowlands DJ,Shields RA,Testa HJ

    更新日期：1979-09-01 00:00:00

  • Multinational development and validation of an early prediction model for delirium in ICU patients.

    abstract：RATIONALE:Delirium incidence in intensive care unit (ICU) patients is high and associated with poor outcome. Identification of high-risk patients may facilitate its prevention. PURPOSE:To develop and validate a model based on data available at ICU admission to predict delirium development during a patient's complete I...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00134-015-3777-2

    authors： Wassenaar A,van den Boogaard M,van Achterberg T,Slooter AJ,Kuiper MA,Hoogendoorn ME,Simons KS,Maseda E,Pinto N,Jones C,Luetz A,Schandl A,Verbrugghe W,Aitken LM,van Haren FM,Donders AR,Schoonhoven L,Pickkers P

    更新日期：2015-06-01 00:00:00

  • Weaning-induced cardiac dysfunction: where are we today?

    abstract：INTRODUCTION:The concept of weaning-induced cardiac dysfunction emerged 26 years ago with the publication of a clinical study conducted by François Lemaire and collaborators. OBJECTIVES:One objective of this article is to remember the results and the historical context under which our pivotal study was conducted. Anot...

    journal_title：Intensive care medicine

    pub_type： 历史文章,杂志文章,评审

    doi：10.1007/s00134-014-3334-4

    authors： Teboul JL

    更新日期：2014-08-01 00:00:00

  • Cognitive improvement during continuous sedation in critically ill, awake and responsive patients: the Acute Neurological ICU Sedation Trial (ANIST).

    abstract：INTRODUCTION:Most anxiolytics and sedative regimens in the intensive care unit (ICU) impair intellectual function, reducing patient autonomy, and often add to patient morbidity. Using an ICU-validated cognitive assessment tool Adapted Cognitive Exam (ACE), we performed a comparison between dexmedetomidine (DEX) and pro...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/s00134-010-1874-9

    authors： Mirski MA,Lewin JJ 3rd,Ledroux S,Thompson C,Murakami P,Zink EK,Griswold M

    更新日期：2010-09-01 00:00:00

  • Steady-state trough serum and epithelial lining fluid concentrations of teicoplanin 12 mg/kg per day in patients with ventilator-associated pneumonia.

    abstract：OBJECTIVE:To determine the steady-state trough serum and epithelial lining fluid (ELF) concentrations of teicoplanin 12 mg/kg per day in critically ill patients with ventilator associated pneumonia. DESIGN AND SETTING:Prospective, pharmacokinetic study in the surgical intensive care unit in a university hospital. PAT...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-006-0136-3

    authors： Mimoz O,Rolland D,Adoun M,Marchand S,Breilh D,Brumpt I,Debaene B,Couet W

    更新日期：2006-05-01 00:00:00

  • Post-contrast acute kidney injury in intensive care unit patients: a propensity score-adjusted study.

    abstract：PURPOSE:To examine the association of intravenous iodinated contrast material administration with the subsequent development of post-contrast AKI (PC-AKI), emergent dialysis, and short-term mortality using a propensity score-adjusted analysis of a cohort of intensive care unit (ICU) patients who underwent CT examinatio...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-017-4699-y

    authors： McDonald JS,McDonald RJ,Williamson EE,Kallmes DF,Kashani K

    更新日期：2017-06-01 00:00:00

  • Dialysis disequilibrium syndrome: an unusual cause of respiratory failure in the medical intensive care unit.

    abstract：:We describe a case of the dialysis disequilibrium syndrome (DDS) that was marked by the rapid onset of cerebral edema and the subsequent development of acute respiratory failure. The patient was treated successfully with a combination of mechanical hyperventilation and mannitol. The clinical presentation, pathogenesis...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340051214

    authors： DiFresco V,Landman M,Jaber BL,White AC

    更新日期：2000-05-01 00:00:00

  • Value of Candida antigen and antibody assays for the diagnosis of invasive candidosis in surgical intensive care patients.

    abstract：:During a 3-year period, a clinical diagnosis of invasive candidosis was made in 8 out of 2054 consecutive surgical intensive care unit (ICU) patients. These patients were retrospectively matched with 16 control patients who underwent similar surgical procedures and had a similar clinical course except for negative Can...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340100891

    authors： Lepper PM,Wiedeck H,Geldner G,Essig A,Trautmann M

    更新日期：2001-05-01 00:00:00

  • Hemodynamic effects of partial liquid ventilation with perfluorocarbon in acute lung injury.

    abstract：OBJECTIVE:To assess the effect of partial liquid ventilation with perfluorocarbons on hemodynamics and gas exchange in large pigs with induced acute lung injury (ALI). DESIGN:Randomized, prospective, double-control, experimental study. Experimental intensive care unit of a university. MATERIALS:Eighteen large pigs (5...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01700657

    authors： Houmes RJ,Verbrugge SJ,Hendrik ER,Lachmann B

    更新日期：1995-12-01 00:00:00

  • The association between hyperoxia and patient outcomes after cardiac arrest: analysis of a high-resolution database.

    abstract：PURPOSE:Previous observational studies have inconsistently associated early hyperoxia with worse outcomes after cardiac arrest, and have methodological limitations. We tested this association using a high-resolution database controlling for multiple disease-specific markers of severity of illness and care processes. M...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-014-3555-6

    authors： Elmer J,Scutella M,Pullalarevu R,Wang B,Vaghasia N,Trzeciak S,Rosario-Rivera BL,Guyette FX,Rittenberger JC,Dezfulian C,Pittsburgh Post-Cardiac Arrest Service (PCAS).

    更新日期：2015-01-01 00:00:00

  • Auto-PEEP and dynamic hyperinflation in COPD patients during controlled mechanical ventilation and high frequency jet ventilation.

    abstract：:We investigated the levels of auto-PEEP and dynamic hyperinflation during high frequency jet ventilation (HFJV) and controlled mechanical ventilation (CMV) in six patients with chronic obstructive pulmonary disease within the first 36 h of acute exacerbation. The comparative evaluation was performed at similar conditi...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF02575298

    authors： Conti G,Bufi M,Rocco M,Calzecchi E,De Blasi RA,Antonelli M,Pelaia P,Gasparetto A

    更新日期：1990-01-01 00:00:00

  • Thoracic ultrasonography: a narrative review.

    abstract：:This narrative review focuses on thoracic ultrasonography (lung and pleural) with the aim of outlining its utility for the critical care clinician. The article summarizes the applications of thoracic ultrasonography for the evaluation and management of pneumothorax, pleural effusion, acute dyspnea, pulmonary edema, pu...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/s00134-019-05725-8

    authors： Mayo PH,Copetti R,Feller-Kopman D,Mathis G,Maury E,Mongodi S,Mojoli F,Volpicelli G,Zanobetti M

    更新日期：2019-09-01 00:00:00

  • Arginine vasopressin does not alter mucosal tissue oxygen tension and oxygen supply in an acute endotoxemic pig model.

    abstract：OBJECTIVE:To determine the effects of increasing dosages of continuously infused arginine-vasopressin (AVP) on mucosal tissue oxygen tension and oxygen supply in an auto-perfused, innervated jejunal segment in an acute endotoxic porcine model. DESIGN:Prospective, randomized, experimental study. SETTING:University hos...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-005-2858-z

    authors： Knotzer H,Maier S,Dünser MW,Hasibeder WR,Hausdorfer H,Brandner J,Torgersen C,Ulmer H,Friesenecker B,Iannetti C,Pajk W

    更新日期：2006-01-01 00:00:00

  • The combination of the load/force balance and the frequency/tidal volume can predict weaning outcome.

    abstract：OBJECTIVE:To examine whether an appropriately designed combination of an index of ventilatory endurance and the frequency divided by tidal volume ratio (f/VT) provides prognostic information for weaning outcome not offered by any index alone. DESIGN AND SETTING:Prospective study in a multidisciplinary intensive care u...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-006-0104-y

    authors： Vassilakopoulos T,Routsi C,Sotiropoulou C,Bitsakou C,Stanopoulos I,Roussos C,Zakynthinos S

    更新日期：2006-05-01 00:00:00

  • Effects of controlled mechanical ventilation on respiratory muscle contractile properties in rabbits.

    abstract：OBJECTIVE:We examined in rabbits the effects of more than 48 h of mechanical ventilation on the contractile properties and fiber type adaptations of the respiratory muscles. DESIGN AND SETTING:Experimental prospective study in a university laboratory. ANIMALS AND INTERVENTIONS:Nineteen rabbits were randomly allocated...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-002-1548-3

    authors： Capdevila X,Lopez S,Bernard N,Rabischong E,Ramonatxo M,Martinazzo G,Prefaut C

    更新日期：2003-01-01 00:00:00

  • Role of replacement fluids in the immediate complications of plasma exchange. French Registry Cooperative Group.

    abstract：OBJECTIVE:Comparison of side effects (fever shivering and/or allergic reactions, collapse, symptomatic hypocalcaemia) of the different substitution fluids used during therapeutical plasmapheresis. DESIGN:Multicentric retrospective comparative study designed to explore the side effects due to the replacements fluids (a...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s001340050595

    authors： Korach JM,Berger P,Giraud C,Le Perff-Desman C,Chillet P

    更新日期：1998-05-01 00:00:00

  • Predictors of prolonged weaning and survival during ventilator weaning in a respiratory ICU.

    abstract：PURPOSE:An International Consensus Conference proposed classifying weaning into simple, difficult, and prolonged weaning. However, the usefulness of this classification in a respiratory intensive care unit (ICU) is unknown. The aims of the study were: (1) to compare the clinical characteristics and outcomes of patients...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-011-2179-3

    authors： Sellares J,Ferrer M,Cano E,Loureiro H,Valencia M,Torres A

    更新日期：2011-05-01 00:00:00

  • Reliability in diagnosis of brain death.

    abstract：OBJECTIVE:To compare some of the confirmatory investigations of brain death with clinical criteria in order to achieve the most sensitive and accurate diagnosis of brain death. DESIGN:All patients with isolated brain lesions and Glasgow Coma Scale (GCS) = 3 were subjected to neurological examination after ruling out h...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01711544

    authors： Paolin A,Manuali A,Di Paola F,Boccaletto F,Caputo P,Zanata R,Bardin GP,Simini G

    更新日期：1995-08-01 00:00:00

  • To-and-fro veno-venous extracorporeal lung assist for newborns with severe respiratory distress.

    abstract：:A veno-venous to-and-fro bypass method through a single blood access for extracorporeal lung assist with an artificial membrane lung is introduced. A premature newborn with severe respiratory distress was treated with this method. A 12 Fr. single lumen catheter with a spiral-embedded thin-wall, 0.25 mm in wall thickne...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF00271065

    authors： Tsuno K,Terasaki H,Tsutsumi R,Sadanaga M,Higashi K,Morioka T

    更新日期：1989-01-01 00:00:00

  • Quinine-induced disseminated intravascular coagulation: case report and review of the literature.

    abstract：OBJECTIVE:To describe the clinical course of quinine-induced disseminated intravascular coagulation (DIC) and review all previous cases reported in the medical literature. DESIGN:Case report/literature review. SETTING:University teaching hospital medical ICU. PATIENTS:One patient in whom thrombocytopenia, coagulopat...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/s00134-003-1732-0

    authors： Knower MT,Bowton DL,Owen J,Dunagan DP

    更新日期：2003-06-01 00:00:00

  • Validation of pediatric index of mortality 2 (PIM2) in a single pediatric intensive care unit in Japan.

    abstract：OBJECTIVE:The Pediatric Index of Mortality 2 (PIM2), one of the key mortality prediction models for children in intensive care units, has not been validated in Japan. The purpose of this study was to validate the performance of PIM2 in a population of patients admitted to one pediatric intensive care unit (PICU) in Jap...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-011-2460-5

    authors： Imamura T,Nakagawa S,Goldman RD,Fujiwara T

    更新日期：2012-04-01 00:00:00

  • Adverse cardiac events during catecholamine vasopressor therapy: a prospective observational study.

    abstract：PURPOSE:To determine the incidence of and risk factors for adverse cardiac events during catecholamine vasopressor therapy in surgical intensive care unit patients with cardiovascular failure. METHODS:The occurrence of any of seven predefined adverse cardiac events (prolonged elevated heart rate, tachyarrhythmia, myoc...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2531-2

    authors： Schmittinger CA,Torgersen C,Luckner G,Schröder DC,Lorenz I,Dünser MW

    更新日期：2012-06-01 00:00:00

  • Continuous flush devices for vascular pressure monitoring.

    abstract：:Six different types of continuous flush devices have been assessed for accuracy in vitro and ease of use in vivo. Only two types of device matched the manufacturers' specifications of performance. The other four gave higher flow rates than expected. ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01691259

    authors： Rithalia SV,Tinker J

    更新日期：1983-01-01 00:00:00

  • Bile canaliculi are defective in hepatic involvement of organ failure and recovery of liver function is due to their secondary regeneration.

    abstract：OBJECTIVE:To investigate the morphological changes in the liver in patients with organ failure and hyperbilirubinemia and to correlate them to the outcome. DESIGN:A case series prospective study. SETTING:Intensive care units of two general hospitals. PATIENTS:Twelve patients in organ failure with predominant hepatic...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01708095

    authors： Douzinas EE,Vamvasakis E,Rigas K,Pitaridis M,Kittas C,Roussos C

    更新日期：1996-06-01 00:00:00

  • Plasma and lung concentrations of ceftazidime administered in continuous infusion to critically ill patients with severe nosocomial pneumonia.

    abstract：OBJECTIVE:To determine the steady-state plasma and epithelial lining fluid (ELF) concentrations of ceftazidime administered in continuous infusion to critically ill patients with severe nosocomial pneumonia. DESIGN:Prospective, open-label study. SETTING:An intensive care unit and research ward in a university hospita...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00134-004-2171-2

    authors： Boselli E,Breilh D,Rimmelé T,Poupelin JC,Saux MC,Chassard D,Allaouchiche B

    更新日期：2004-05-01 00:00:00

  • Genetic variants in the angiopoietin-2 gene are associated with increased risk of ARDS.

    abstract：OBJECTIVE:Angiopoietin-2 (Ang-2) is a potent regulator of vascular permeability and inflammation in acute lung injury and acute respiratory distress syndrome (ARDS). Genetic variants in the Ang-2 gene may lead to altered activities of Ang-2 (or ANGPT2) gene. The aim of this study was to assess if genetic variants of An...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-009-1413-8

    authors： Su L,Zhai R,Sheu CC,Gallagher DC,Gong MN,Tejera P,Thompson BT,Christiani DC

    更新日期：2009-06-01 00:00:00

  • Extracorporeal treatment of acute renal failure in the intensive care unit: a critical view.

    abstract：:Acute renal failure in critically ill patients is seldom an isolated problem but is more usually associated with multiple organ failure. When choosing an extracorporeal kidney replacement therapy, these other failing organs must be taken into account. Therefore the choice of an artificial kidney in patients requiring ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/BF00261492

    authors： Schetz M,Lauwers PM,Ferdinande P

    更新日期：1989-01-01 00:00:00

  • Oxidative parameters and mortality in sepsis induced by cecal ligation and perforation.

    abstract：OBJECTIVE:This study assessed parameters of free radical damage to biomolecules, mitochondrial superoxide production, superoxide dismutase, and catalase activities and their relationship to sepsis mortality. DESIGN AND SETTING:Prospective animal study in a university laboratory for experimental. SUBJECTS:140 male Wis...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-003-1789-9

    authors： Ritter C,Andrades M,Frota Júnior ML,Bonatto F,Pinho RA,Polydoro M,Klamt F,Pinheiro CT,Menna-Barreto SS,Moreira JC,Dal-Pizzol F

    更新日期：2003-10-01 00:00:00