Auto-PEEP and dynamic hyperinflation in COPD patients during controlled mechanical ventilation and high frequency jet ventilation.

abstract：PURPOSE:Sepsis and its progression are known to have a major influence on the coagulation system. Current coagulation tests are of limited use when assessing coagulation in sepsis patients. This study aims to assess the potential for a new functional biomarker of clot microstructure, fractal dimension, to identify chan...

journal_title：Intensive care medicine

authors： Davies GR,Pillai S,Lawrence M,Mills GM,Aubrey R,D'Silva L,Battle C,Williams R,Brown R,Thomas D,Morris K,Evans PA

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:Although several advantages are attributed to tracheotomy in ICU patients requiring mechanical ventilation (MV), true benefits and the optimal timing of tracheotomy remain controversial. In this study, we compared early tracheotomy (ET) with prolonged intubation (PI) in severely ill patients requiring prolong...

journal_title：Intensive care medicine

authors： Blot F,Similowski T,Trouillet JL,Chardon P,Korach JM,Costa MA,Journois D,Thiéry G,Fartoukh M,Pipien I,Bruder N,Orlikowski D,Tankere F,Durand-Zaleski I,Auboyer C,Nitenberg G,Holzapfel L,Tenaillon A,Chastre J,Laplanch

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:This study was undertaken to determine the delay of extubation attributable to ventilator-associated pneumonia (VAP) in comparison to other complications and complexity of surgery after repair of congenital heart lesions in neonates and children. METHODS:Cohort study in a pediatric intensive care unit of a t...

journal_title：Intensive care medicine

authors： Fischer JE,Allen P,Fanconi S

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To assess if the observed respiratory cycle-related variation in intra-abdominal pressure is reliably quantifiable and a possible indirect indicator of abdominal compliance. Secondary issues were to assess the roles played by respiratory parameters in determining this oscillation and by patients' position in ...

journal_title：Intensive care medicine

authors： Sturini E,Saporito A,Sugrue M,Parr MJ,Bishop G,Braschi A

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:We examined whether early diffusion-weighted magnetic resonance imaging (DW-MRI) abnormalities of the brain and variation of apparent diffusion coefficient (ADC) values can provide prognostic information on clinical outcome in children following cardiac arrest (CA). DESIGN:Retrospective study. SETTING:A 12-...

journal_title：Intensive care medicine

authors： Oualha M,Gatterre P,Boddaert N,Dupic L,De Saint Blanquat L,Hubert P,Lesage F,Desguerre I

更新日期：2013-07-01 00:00:00

abstract：:Nosocomial infections are a major problem in intensive care patients. Thirty-nine patients, requiring intensive care for 5 days or more (mean 15.8 days) were prospectively investigated, to determine the relation between colonisation and nosocomial infection. Thrice weekly, cultures from the oropharynx, respiratory and...

journal_title：Intensive care medicine

authors： Kerver AJ,Rommes JH,Mevissen-Verhage EA,Hulstaert PF,Vos A,Verhoef J,Wittebol P

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:Evidence of variation in mortality after surgery may indicate preventable postoperative death. We sought to determine if regional differences in outcome were present in surgical patients admitted to critical care in the UK. METHODS:We extracted data on admission characteristics, case mix and outcome of all pat...

journal_title：Intensive care medicine

authors： Gillies MA,Power GS,Harrison DA,Fleming A,Cook B,Walsh TS,Pearse RM,Rowan KM

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:The pressure-volume (P/V) curve has been proposed as a tool to adjust the ventilatory settings in cases of acute respiratory distress syndrome (ARDS). The aim of this study was to test the influence of P/V tracing methodology on the presence and value of the upper inflection point (UIP). METHODS:In 13 medica...

journal_title：Intensive care medicine

authors： Servillo G,De Robertis E,Maggiore S,Lemaire F,Brochard L,Tufano R

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective study was to evaluate the value of sinus echography results to directly indicate a transnasal puncture in intubated patients with suspicion of nosocomial maxillary sinusitis. DESIGN:prospective clinical investigation. SETTING:medical intensive care unit. PATIENTS:sixty patients ...

journal_title：Intensive care medicine

authors： Vargas F,Bui HN,Boyer A,Bébear CM,Lacher-Fougére S,De-Barbeyrac BM,Salmi LR,Traissac L,Gbikpi-Benissan G,Gruson D,Hilbert G

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:Providing mechanical ventilation is challenging at supra-atmospheric pressure. The higher gas density increases resistance, reducing the flow delivered by the ventilator. A new hyperbaric ventilator (Siaretron IPER 1000) is said to compensate for these effects automatically. The aim of this bench test study was...

journal_title：Intensive care medicine

authors： Lefebvre JC,Lyazidi A,Parceiro M,Sferrazza Papa GF,Akoumianaki E,Pugin D,Tassaux D,Brochard L,Richard JC

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:To determine whether, during mechanical ventilation, an optimal positive end-expiratory pressure (PEEP) can be identified by measurement of regional tidal volume and compliance [V (T(reg)), C (RS(reg))]. METHODS:Sixteen anaesthetized intubated neonatal piglets underwent a stepwise vital capacity manoeuvre perf...

journal_title：Intensive care medicine

authors： Dargaville PA,Rimensberger PC,Frerichs I

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:Angiopoietin-2 (Ang-2) is a potent regulator of vascular permeability and inflammation in acute lung injury and acute respiratory distress syndrome (ARDS). Genetic variants in the Ang-2 gene may lead to altered activities of Ang-2 (or ANGPT2) gene. The aim of this study was to assess if genetic variants of An...

journal_title：Intensive care medicine

authors： Su L,Zhai R,Sheu CC,Gallagher DC,Gong MN,Tejera P,Thompson BT,Christiani DC

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:Inhalation of high concentrations of nitric oxide (NO) has been shown to improve gas exchange and to reduce pulmonary vascular resistance in individuals with ischemia-reperfusion injury following orthotopic lung transplantation. We assessed the cardiopulmonary effects of low doses of NO in early allograft dys...

journal_title：Intensive care medicine

authors： Kemming GI,Merkel MJ,Schallerer A,Habler OP,Kleen MS,Haller M,Briegel J,Vogelmeier C,Fürst H,Reichart B,Zwissler B

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To evaluate a least squares fitting technique for the purpose of measuring total respiratory compliance (Crs) and resistance (Rrs) in patients submitted to partial ventilatory support, without the need for esophageal pressure measurement. DESIGN:Prospective, randomized study. SETTING:A general ICU of a Univ...

journal_title：Intensive care medicine

authors： Iotti GA,Braschi A,Brunner JX,Smits T,Olivei M,Palo A,Veronesi R

更新日期：1995-05-01 00:00:00

abstract：PURPOSE:Reporting neurodevelopmental outcome of 8-year-old children treated with neonatal extracorporeal membrane oxygenation (ECMO). METHODS:In a follow-up study in 135 8-year-old children who received neonatal ECMO between 1996 and 2001 we assessed intelligence (Revised Amsterdam Intelligence Test), concentration (B...

journal_title：Intensive care medicine

authors： Madderom MJ,Reuser JJ,Utens EM,van Rosmalen J,Raets M,Govaert P,Steiner K,Gischler SJ,Tibboel D,van Heijst AF,Ijsselstijn H

更新日期：2013-09-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Stefani A,Ruggiero C,Aramini B,Scamporlino A

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To compare characteristics, clinical evolution and outcome in adult patients with influenza A (H1N1) acute respiratory distress syndrome (ARDS) treated with or without extracorporeal membrane oxygenation (ECMO). METHODS:A prospective observational study of patients treated in Marseille South Hospital from Octo...

journal_title：Intensive care medicine

authors： Roch A,Lepaul-Ercole R,Grisoli D,Bessereau J,Brissy O,Castanier M,Dizier S,Forel JM,Guervilly C,Gariboldi V,Collart F,Michelet P,Perrin G,Charrel R,Papazian L

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was (1) to determine the prevalence of intensive care unit (ICU) admissions due to an adverse drug reaction (ADR), and (2) to compare affected patients with patients admitted to the ICU for the treatment of deliberate self-poisoning using medical drugs. DESIGN:Prospective observa...

journal_title：Intensive care medicine

authors： Schwake L,Wollenschläger I,Stremmel W,Encke J

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:To assess the impact of lung ultrasound (LU) on clinical decision making in mechanically ventilated critically ill patients. METHODS:One hundred and eighty-nine patients took part in this prospective study. The patients were enrolled in the study when LU was requested by the primary physician for (1) unexplain...

journal_title：Intensive care medicine

authors： Xirouchaki N,Kondili E,Prinianakis G,Malliotakis P,Georgopoulos D

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Fluid overload is a risk factor for poor outcome in intensive care; thus volume loading should be tailored towards patients who are likely to increase stroke volume. We aimed to evaluate the paediatric predictive ability (stroke volume increase of at least 15 % after fluid bolus) of novel and established volume...

journal_title：Intensive care medicine

authors： Saxena R,Durward A,Steeley S,Murdoch IA,Tibby SM

更新日期：2015-12-01 00:00:00

abstract：:Acute renal failure in critically ill patients is seldom an isolated problem but is more usually associated with multiple organ failure. When choosing an extracorporeal kidney replacement therapy, these other failing organs must be taken into account. Therefore the choice of an artificial kidney in patients requiring ...

journal_title：Intensive care medicine

authors： Schetz M,Lauwers PM,Ferdinande P

更新日期：1989-01-01 00:00:00

abstract：:Six different types of continuous flush devices have been assessed for accuracy in vitro and ease of use in vivo. Only two types of device matched the manufacturers' specifications of performance. The other four gave higher flow rates than expected. ...

journal_title：Intensive care medicine

authors： Rithalia SV,Tinker J

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:To describe the incidence, risk factors, and impact on mortality of acute kidney injury (AKI) in patients with 2009 influenza A (H1N1) viral pneumonia requiring mechanical ventilation. DESIGN:Observational cohort study. PATIENTS AND METHODS:AKI was defined as risk, injury or failure, according to the RIFLE ...

journal_title：Intensive care medicine

authors： Nin N,Lorente JA,Soto L,Ríos F,Hurtado J,Arancibia F,Ugarte S,Echevarría E,Cardinal P,Saldarini F,Bagnulo H,Cortés I,Bujedo G,Ortega C,Frutos F,Esteban A

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:We examined whether influenza vaccination affects 1-year risk of myocardial infarction, stroke, heart failure, pneumonia, and death among intensive care unit (ICU) survivors aged ≥ 65 years. METHODS:Danish Intensive Care Database data on all elderly ( ≥ 65 years) patients hospitalized in Danish ICUs in the per...

journal_title：Intensive care medicine

authors： Christiansen CF,Thomsen RW,Schmidt M,Pedersen L,Sørensen HT

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:Septic shock induces a decrease in dendritic cells (DCs) that may contribute to sepsis-induced immunosuppression. We analyzed the time course of circulating DCs in patients with septic shock and its relation to susceptibility to intensive care unit (ICU)-acquired infections. METHODS:We enrolled adult patients ...

journal_title：Intensive care medicine

authors： Grimaldi D,Louis S,Pène F,Sirgo G,Rousseau C,Claessens YE,Vimeux L,Cariou A,Mira JP,Hosmalin A,Chiche JD

更新日期：2011-09-01 00:00:00

abstract：:The oxygen cost of breathing (which is the difference in oxygen consumption measured during controlled ventilation and again during spontaneous ventilation) was measured in 30 patients between the ages of 17 and 96 years at the time of commencement of weaning from mechanical ventilation. There was a significant expone...

journal_title：Intensive care medicine

authors： McDonald NJ,Lavelle P,Gallacher WN,Harpin RP

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:To compare the effects of norepinephrine and dobutamine to epinephrine on hemodynamics, lactate metabolism, and gastric tonometric variables in hyperdynamic dopamine-resistant septic shock. DESIGN:A prospective, intervention, randomized clinical trial. SETTING:Adult medical/surgical intensive care unit in ...

journal_title：Intensive care medicine

authors： Levy B,Bollaert PE,Charpentier C,Nace L,Audibert G,Bauer P,Nabet P,Larcan A

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:To identify and reduce medication-prescribing errors by introducing systematic physician education and post-cardiac surgery admission prescription forms. DESIGN:Errors were defined as: incomplete prescriptions; potential adverse drug events (ADEs), i.e. either intercepted or non-intercepted incorrect prescri...

journal_title：Intensive care medicine

authors： Burmester MK,Dionne R,Thiagarajan RR,Laussen PC

更新日期：2008-06-01 00:00:00

abstract：:In critically ill patients, it is frequently challenging to identify who will benefit from admission to the intensive care unit and life-sustaining interventions when the chances of a meaningful outcome are unclear. In addition, the acute illness not only affects the patients but also family members or surrogates who ...

journal_title：Intensive care medicine

authors： Vink EE,Azoulay E,Caplan A,Kompanje EJO,Bakker J

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:Critically ill patients often require CT scans. Adverse events (AE) can occur during intra-hospital transport (IHT). The aim of this prospective study was to determine the diagnostic and therapeutic yield and the safety of CT scans in ICU patients. METHODS:All ICU patients having a CT scan for diagnostic purpo...

journal_title：Intensive care medicine

authors： Aliaga M,Forel JM,De Bourmont S,Jung B,Thomas G,Mahul M,Bisbal M,Nougaret S,Hraiech S,Roch A,Chaumoitre K,Jaber S,Gainnier M,Papazian L

更新日期：2015-03-01 00:00:00