Adverse drug reactions and deliberate self-poisoning as cause of admission to the intensive care unit: a 1-year prospective observational cohort study.

abstract：OBJECTIVE:To determine the reliability of estimating arterial CO(2) pressure (PaCO(2)) using a recently introduced transcutaneous CO(2) pressure (PtcCO(2)) monitor in severe obese patients. DESIGN:Observational and interventional study. SETTING:District hospital with respiratory ward and bariatric surgery unit. PATI...

journal_title：Intensive care medicine

authors： Maniscalco M,Zedda A,Faraone S,Carratù P,Sofia M

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To determine whether a goal-directed terlipressin infusion increases mean arterial pressure without causing a pulmonary vasopressive effect and whether this response impacts on key parameters of oxygen transport in healthy and endotoxemic sheep. DESIGN AND SETTING:Prospective controlled trial in a university...

journal_title：Intensive care medicine

authors： Westphal M,Stubbe H,Sielenkämper AW,Borgulya R,Van Aken H,Ball C,Bone HG

更新日期：2003-02-01 00:00:00

abstract：:Two patients with severe hepatic and renal failure underwent emergency hepatic retransplantation (2nd and 6th day after transplantation). Continuous arteriovenous haemodialysis was begun before surgery and successfully performed, without any incident, during the retransplantation with a biospal (SCU/CAVH AN 69 S) devi...

journal_title：Intensive care medicine

authors： Salord F,Bailly MP,Gaussorgues P,Workineh S,Pouyet M,Robert D

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:Neurologic and endothelial injury biomarkers are associated with prolonged delirium during critical illness and may reflect injury pathways that lead to poor long-term outcomes. We hypothesized that blood-brain barrier (BBB), neuronal, and endothelial injury biomarkers measured during critical illness are assoc...

journal_title：Intensive care medicine

authors： Hughes CG,Patel MB,Brummel NE,Thompson JL,McNeil JB,Pandharipande PP,Jackson JC,Chandrasekhar R,Ware LB,Ely EW,Girard TD

更新日期：2018-03-01 00:00:00

abstract：:Physicians are increasingly involved in how their critically ill patients die [72]. The more this happens, the more physicians will have to understand not only how their own backgrounds and biases influence their medical management, but also the cultural and religious backgrounds of the patient and surrogate [72, 73]....

journal_title：Intensive care medicine

authors： Nyman DJ,Sprung CL

更新日期：2000-10-01 00:00:00

abstract：UNLABELLED:Admission of cancer patients with serious medical complications to the ICU remains controversial primarily because of the high short-term mortality rates in these patients. However, the cancer patient population is heterogeneous regarding age, underlying conditions, and curability of their disease, suggestin...

journal_title：Intensive care medicine

authors： Azoulay E,Moreau D,Alberti C,Leleu G,Adrie C,Barboteu M,Cottu P,Levy V,Le Gall JR,Schlemmer B

更新日期：2000-12-01 00:00:00

abstract：PURPOSE:To assess the generalisability of published clinical risk predictive models for invasive candidiasis in ICU patients. METHODS:The performance characteristics of published clinical risk factor-only and Candida colonisation-only predictive models for invasive candidiasis were assessed in a multicentre cohort of ...

journal_title：Intensive care medicine

authors： Playford EG,Lipman J,Kabir M,McBryde ES,Nimmo GR,Lau A,Sorrell TC

更新日期：2009-12-01 00:00:00

abstract：:The effect of plasma exchange (PE) was evaluated in 4 patients with rhabdomyolysis. A single 21 PE produced a transient fall of creatinine phosphokinase and did not prevent renal failure. Theoretically PE would need to be performed very frequently to remove toxins in appropriate amounts. Since renal failure in myoglob...

journal_title：Intensive care medicine

authors： Cornelissen JJ,Haanstra W,Haarman HJ,Derksen RH

更新日期：1989-01-01 00:00:00

abstract：:A prospective study of thiamine status in patients with severe injuries (injury severity scores greater than 12) showed that they all developed signs of severe thiamine deficiency on the basis of transketolase activity, the standard biochemical test for thiamine deficiency. This occurred within the first week after th...

journal_title：Intensive care medicine

authors： McConachie I,Haskew A

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:Lung injury is a severe complication of acute pancreatitis that increases the mortality rate of the disease. The pathophysiology of acute pancreatitis has been studied in several experimental models, but the kinetics of pulmonary complications in relation to the pancreatic disease is not completely understood...

journal_title：Intensive care medicine

authors： Morel DR,Frossard JL,Cikirikcioglu B,Tapponnier M,Pastor CM

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:Brain death may induce cardiac dysfunction. In potential organ donors measurements of N-terminal pro-brain natriuretic peptide (NT-proBNP) and circulating cardiac troponins T and I (cTnT and cTnI), alone or in combination, are performed to investigate the accuracy of these biomarkers for early diagnosis of le...

journal_title：Intensive care medicine

authors： Nicolas-Robin A,Salvi N,Medimagh S,Amour J,Le Manach Y,Coriat P,Riou B,Langeron O

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To clarify the risk of secondary exposure of medical staff to sarin vapor in the emergency room, and to warn emergency room staffs of the hazard. DESIGN:Retrospective observational survey. SETTING:Emergency department of a university hospital in a metropolitan area of Japan. PARTICIPANTS:Fifteen doctors tr...

journal_title：Intensive care medicine

authors： Nozaki H,Hori S,Shinozawa Y,Fujishima S,Takuma K,Sagoh M,Kimura H,Ohki T,Suzuki M,Aikawa N

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:To assess procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations and clearance in nonseptic end-stage renal failure patients undergoing their first three hemodialysis sessions. DESIGN AND SETTING:Prospective observational consecutive clinical study at a university hospital. PATIENTS:The stud...

journal_title：Intensive care medicine

authors： Dahaba AA,Rehak PH,List WF

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To evaluate whether helium-oxygen mixture reduces inspiratory work of breathing (WOB) in sedated, paralyzed, and mechanically ventilated patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). DESIGN AND SETTING:Open, prospective, randomized, crossover study in the medical intensive...

journal_title：Intensive care medicine

authors： Gainnier M,Arnal JM,Gerbeaux P,Donati S,Papazian L,Sainty JM

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To assess whether monitoring of bladder epithelial oxygen tension (BEOT) would provide an indication of regional (renal) organ perfusion in an exsanguination/fluid repletion animal model. DESIGN:Prospective non-randomized laboratory study. SETTING:Research laboratory. INTERVENTIONS:Eight anaesthetised, spo...

journal_title：Intensive care medicine

authors： Singer M,Millar C,Stidwill R,Unwin R

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:The liver plays a key role in the inflammatory response during major surgery or infection. The influence of age on liver function and hepatic acute phase protein (APP) synthesis should be serially studied in elderly patients undergoing major abdominal surgery. DESIGN AND SETTING:Prospective and descriptive s...

journal_title：Intensive care medicine

authors： Suttner SW,Sürder C,Lang K,Piper SN,Kumle B,Boldt J

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficiency of a new device developed to remove obstructions from endotracheal tubes (ETT) in mechanically ventilated patients. DESIGN:Open study in mechanically ventilated sedated and paralyzed ICU patients. SETTING:General ICU and Laboratory of Respiratory Mechanics of the University of Rom...

journal_title：Intensive care medicine

authors： Conti G,Rocco M,De Blasi RA,Lappa A,Antonelli M,Bufi M,Gasparetto A

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:In normal subjects cerebral CO2 vasoreactivity is measured during spontaneous hyperventilation, breathholding, or adding CO2 to inspiratory gases. The correlation between CO2 and cerebral blood flow may, however, be invalidated by the effects of a modified respiratory pattern on venous return, sympathovagal b...

journal_title：Intensive care medicine

authors： Cigada M,Marzorati S,Tredici S,Iapichino G

更新日期：2000-06-01 00:00:00

abstract：:The World Health Organization defines overweight and obesity as the condition where excess or abnormal fat accumulation increases risks to health. The prevalence of obesity is increasing worldwide and is around 20% in ICU patients. Adipose tissue is highly metabolically active, and especially visceral adipose tissue h...

journal_title：Intensive care medicine

authors： Schetz M,De Jong A,Deane AM,Druml W,Hemelaar P,Pelosi P,Pickkers P,Reintam-Blaser A,Roberts J,Sakr Y,Jaber S

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Nuclear factor-kappaB (NF-kappaB) is a transcription factor which plays a pivotal role in the induction of genes involved in the response to injury and inflammation. Calpain I inhibitor is a potent antioxidant which is an effective inhibitor of NF-kappaB. This study examined whether the postulate that calpain...

journal_title：Intensive care medicine

authors： Virlos I,Mazzon E,Serraino I,Genovese T,Di Paola R,Thiemerman C,Siriwardena A,Cuzzocrea S

更新日期：2004-08-01 00:00:00

abstract：:Intravenous bolus endotoxin elicits a marked but transient increase in plasma TxB2 and 6-keto-PGF1 alpha in a large number of species. A smaller, delayed and more prolonged increase in TxB2 and 6-keto-PGF1 alpha are reported in animals with septic shock, i.e., those with fecal peritonitis or cecal ligation. Thromboxan...

journal_title：Intensive care medicine

authors： Ball HA,Cook JA,Wise WC,Halushka PV

更新日期：1986-01-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Stefani A,Ruggiero C,Aramini B,Scamporlino A

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:The intravenous fluid 6% hydroxyethyl starch (130/0.4) (6% HES 130/0.4) is used widely for resuscitation but there is limited information on its efficacy and safety. A large-scale multi-centre randomised controlled trial (CHEST) in critically ill patients is currently underway comparing fluid resuscitation with...

journal_title：Intensive care medicine

authors： Crystalloid versus Hydroxyethyl Starch Trial (CHEST) Management Committee.

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Adverse respiratory and gasometrical effects have been described in patients with acute respiratory failure (ARF) undergoing noninvasive ventilation (NIV) with standard heat and moisture exchangers (HME). We decided to evaluate respiratory parameters and arterial blood gases (ABG) of patients during NIV with ...

journal_title：Intensive care medicine

authors： Boyer A,Vargas F,Hilbert G,Gruson D,Mousset-Hovaere M,Castaing Y,Dreyfuss D,Ricard JD

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:We describe a patient with a prolonged and severe hypercapnia occurring during an episode of status asthmaticus induced by ophthalmic instillation of carteolol. SETTING:Prehospital Emergency Medical Service and Pulmonary Intensive Care Unit in a university hospital. PATIENT:A 35-year-old female developed an...

journal_title：Intensive care medicine

authors： Adnet F,Plaisance P,Borron SW,Levy A,Payen D

更新日期：1998-12-01 00:00:00

abstract：PURPOSE:The early diagnosis of traumatic internal carotid artery dissection (TICAD) is essential for initiating appropriate treatment and improving outcome. We searched for criteria from transcranial Doppler (TCD) measurements on admission that could be associated with subsequent TICAD diagnosis in patients with trauma...

journal_title：Intensive care medicine

authors： Bouzat P,Francony G,Brun J,Lavagne P,Picard J,Broux C,Declety P,Jacquot C,Albaladejo P,Payen JF

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To provide recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza pandemic or mass disaster with a specific focus on essential equipment, pharmaceuticals and supplies. METHODS:Based on a literature review and expert opinion, a Delphi process was use...

journal_title：Intensive care medicine

authors： Sprung CL,Kesecioglu J,European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mass disaster.

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To assess the value of the diagnosis of overt disseminated intravascular coagulation (DIC) according to the International Society on Thrombosis and Haemostasis (ISTH) criteria and that of the parameters included in the ISTH score for overt DIC in predicting day 28 mortality in intensive care patients. Also, t...

journal_title：Intensive care medicine

authors： Sivula M,Tallgren M,Pettilä V

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To assess noise exposure during noninvasive ventilation (NIV) with different types of interface (helmet, nasal, and facial masks). SUBJECTS AND METHODS:Ten "naive" healthy volunteers underwent NIV at pressure support levels of 10 and 15 cmH2O with: (a) helmet, (b) helmet equipped with HME filters at the junc...

journal_title：Intensive care medicine

authors： Cavaliere F,Conti G,Costa R,Proietti R,Sciuto A,Masieri S

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:Percutaneous dilatational tracheostomy is increasingly practiced in intensive care units and has a low incidence of early complications. The late effects of this procedure are still poorly known and were the focus of this study. DESIGN:Prospective descriptive clinical study. SETTING:Interdisciplinary intens...

journal_title：Intensive care medicine

authors： Fischler MP,Kuhn M,Cantieni R,Frutiger A

更新日期：1995-06-01 00:00:00