Abstract：
PURPOSE:The early diagnosis of traumatic internal carotid artery dissection (TICAD) is essential for initiating appropriate treatment and improving outcome. We searched for criteria from transcranial Doppler (TCD) measurements on admission that could be associated with subsequent TICAD diagnosis in patients with traumatic brain injury (TBI). METHODS:We conducted a retrospective 1:4 matched (age, mean arterial blood pressure) cohort study of 11 TBI patients with TICAD and absent or mild brain lesions on initial CT scan, 22 TBI controls with comparable brain CT scan lesions (controls 1), and 22 TBI controls with more severe brain CT scan lesions (controls 2) on admission. TCD measurements were obtained on admission from both middle cerebral arteries (MCA). All patients had subsequent CT angiography to diagnose TICAD. RESULTS:A >25% asymmetry in the systolic blood flow velocity between the two MCA was found in 9/11 patients with TICAD versus 0/22 in controls 1 and 5/22 in controls 2 (p < 0.01). The combination of this asymmetry with an ipsilateral pulsatility index < or =0.80 was found in 9/11 patients with TICAD versus none in the two groups of controls (p < 0.01). CONCLUSIONS:Our results suggest that significant asymmetry in the systolic blood flow velocity between the MCAs and a reduced ipsilateral pulsatility index could be criteria from TCD measurements associated with the occurrence of TICAD in head-injured patients. If prospectively validated, these findings could be incorporated in screening protocols for TICAD in patients with TBI.
journal_name
Intensive Care Medjournal_title
Intensive care medicineauthors
Bouzat P,Francony G,Brun J,Lavagne P,Picard J,Broux C,Declety P,Jacquot C,Albaladejo P,Payen JFdoi
10.1007/s00134-010-1919-0subject
Has Abstractpub_date
2010-09-01 00:00:00pages
1514-20issue
9eissn
0342-4642issn
1432-1238journal_volume
36pub_type
杂志文章abstract：OBJECTIVES:(a). To describe the glucose content of normal human airways secretions; (b). to observe the effects of hyperglycemia and airways inflammation on airways glucose. DESIGN:Observational studies. SETTINGS:(a). St George's Hospital Medical School; (b). diabetes mellitus outpatient clinics; (c). adult general i...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-003-1961-2
更新日期：2003-12-01 00:00:00
abstract：OBJECTIVE:To assess the relationship between the base deficit value in the immediate postoperative period of coronary surgery for cardiopulmonary bypass and the length of stay in the ICU. DESIGN AND SETTING:Prospective descriptive study in the department of anesthesia and cardiovascular surgery of a university hospita...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-002-1587-9
更新日期：2003-02-01 00:00:00
abstract：OBJECTIVE:To investigate whether the respiratory variation in inferior vena cava diameter (DeltaD(IVC)) could be related to fluid responsiveness in mechanically ventilated patients. DESIGN:Prospective clinical study. SETTING:Medical ICU of a non-university hospital. PATIENTS:Mechanically ventilated patients with sep...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-004-2233-5
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVE:To determine the magnitude and time course of adrenergic effects on metabolism in volunteers and possible implications for the use of sympathomimetics in the critically ill. DESIGN:Descriptive laboratory investigation. SUBJECTS:7 volunteers. INTERVENTION:Primed continuous infusions of stable isotope tracer...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01707665
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVE:To measure water balance and changes in distribution, and the effect of giving supplementary albumin, early after a burn injury. DESIGN:Consecutive patients (matched groups) and healthy controls. SETTING:National burn unit in a Swedish university hospital. PATIENTS AND SUBJECTS:Eighteen patients with 18%-9...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340100935
更新日期：2001-05-01 00:00:00
abstract：:During the last two decades, severe group A beta-haemolytic streptococcal infections have been defined as the "toxic strep syndrome", and have been reported not only in immunocompromised or elderly people, but also occasionally in previously healthy patients. We describe 4 patients presenting with the toxic strep synd...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01709279
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Limiting the duration of invasive ventilation is an important goal in caring for critically ill patients. Several clinical trials have shown that compared to traditional care, protocols can reduce the total duration of mechanical ventilation. Computerized or automated weaning has the potential to improve wea...
journal_title：Intensive care medicine
pub_type： 杂志文章,评审
doi：10.1007/s00134-008-1154-0
更新日期：2008-10-01 00:00:00
abstract：PURPOSE:To study the incidence and clinical characteristics of delayed cerebral thrombosis in bacterial meningitis patients. METHODS:We assessed the incidence and clinical characteristics of delayed cerebral thrombosis in adults with cerebrospinal fluid (CSF) culture-proven community-acquired bacterial meningitis incl...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-012-2792-9
更新日期：2013-05-01 00:00:00
abstract：INTRODUCTION:Faecal peritonitis (FP) is a common cause of sepsis and admission to the intensive care unit (ICU). The Genetics of Sepsis and Septic Shock in Europe (GenOSept) project is investigating the influence of genetic variation on the host response and outcomes in a large cohort of patients with sepsis admitted t...
journal_title：Intensive care medicine
pub_type： 杂志文章,多中心研究
doi：10.1007/s00134-013-3158-7
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:We determined the effects of two antibiotic policies (predominance of either beta-lactam antibiotics or fluroquinolones) on acquisition with third-generation cephalosporin-resistant Enterobacteriaceae (CRE) and fluoroquinolone-resistant CRE (FCRE) in two ICUs, with monitoring of other variables that may infl...
journal_title：Intensive care medicine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00134-009-1714-y
更新日期：2010-03-01 00:00:00
abstract：: ...
journal_title：Intensive care medicine
pub_type： 评论,社论
doi：10.1007/s00134-018-5399-y
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVE:Sepsis-evoked myocardial dysfunction is possibly due to decreased myofilament calcium sensitivity, and a calcium sensitizer may thus specifically improve contractility in sepsis by enhancing myofilament calcium sensitivity. We examined whether the calcium sensitizer levosimendan mitigates myocardial dysfuncti...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-003-1879-8
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVE:Postoperative pneumonia is a potentially devastating complication associated with high mortality in intensive care unit (ICU)-patients. One of the major predisposing factors is the perioperative occurrence of atelectatic formations in non-dependent lung areas. Perioperative ventilation/perfusion mismatch due ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-008-1122-8
更新日期：2008-10-01 00:00:00
abstract：OBJECTIVE:To describe a real-time ultrasound sign, the visualization of the cavity and the walls of the maxillary sinus ("sinusogram"), and to assess its correlation with total opacity of the sinus. DESIGN:Prospective clinical study. SETTING:The medical ICU of a university-affiliated hospital. PATIENTS:The significa...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340050716
更新日期：1998-10-01 00:00:00
abstract：:The goals of management of patients with respiratory failure include improving arterial oxygenation with PEEP and red cell transfusion to maintain oxygen carrying capacity, both of which contribute to improving tissue oxygen delivery. However, standard CPD-stored blood is rapidly depleted of 2,3 diphosphoglycerate (2,...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF00315364
更新日期：1986-01-01 00:00:00
abstract：OBJECTIVE:To identify objective trends of the course of illness that might be used as benchmarks in the auditing of the organization/performance of Intensive Care Units (ICU). DESIGN:Retrospective analysis. PATIENTS AND SETTING:A group of 12,615 patients and 55,464 patient-days prospectively collected in 89 ICUs of 1...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-002-1331-5
更新日期：2002-07-01 00:00:00
abstract：:In order to evaluate the in vitro activity of fleroxacin against nosocomial gram-negative organisms, 263 multiresistant gram-negative bacilli (203 Enterobacteriaceae and 60 non-fermenting gram-negative bacilli) were isolated from adult patients with nosocomial infections. The different patterns of resistance to eight ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340050675
更新日期：1998-08-01 00:00:00
abstract：OBJECTIVE:Organophosphate toxicity is the leading cause of morbidity and death in poisoning by insecticides. The clinical symptoms of pesticide toxicity range from the classic cholinergic syndrome to flaccid paralysis and intractable seizures. The mainstays of therapy are atropine, oximes, benzodiazepines and supportiv...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-005-0051-z
更新日期：2006-03-01 00:00:00
abstract：:Breathing pattern was studied non-invasively in 20 coronary artery bypass surgery patients before the operation and post-operatively after weaning from mechanical ventilation. Post-operatively minute ventilation (VE), breathing frequency (Fr) and mean inspiratory flow (VT/TI) increased (28%, 42%, 27%; p less than 0.01...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01716198
更新日期：1991-01-01 00:00:00
abstract：OBJECTIVE:The aim of the present study was (1) to determine the prevalence of intensive care unit (ICU) admissions due to an adverse drug reaction (ADR), and (2) to compare affected patients with patients admitted to the ICU for the treatment of deliberate self-poisoning using medical drugs. DESIGN:Prospective observa...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-008-1250-1
更新日期：2009-02-01 00:00:00
abstract：:A case of bilateral pseudoaneurysms of the pulmonary arteries caused by blunt chest injury is presented. Although this is a very rare complication, this entity should always be suspected in a patient with hemoptysis and a radiodensity on chest radiograph following chest injury. Selection of operative procedures should...
journal_title：Intensive care medicine
pub_type： 杂志文章,评审
doi：10.1007/BF01706428
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the impact of two different comorbidity measures on the 6-month mortality of severely ill cancer patients. DESIGN AND SETTING:Prospective cohort study in a ten-bed oncological medical-surgical intensive care unit (ICU). PATIENTS:A total of 772 consecutive patients were included over a 45-month p...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-005-2554-z
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:To assess the generalisability of published clinical risk predictive models for invasive candidiasis in ICU patients. METHODS:The performance characteristics of published clinical risk factor-only and Candida colonisation-only predictive models for invasive candidiasis were assessed in a multicentre cohort of ...
journal_title：Intensive care medicine
pub_type： 杂志文章,多中心研究
doi：10.1007/s00134-009-1619-9
更新日期：2009-12-01 00:00:00
abstract：PURPOSE:To evaluate the diagnostic accuracy of ultrasonography of optic nerve sheath diameter (ONSD) for assessment of intracranial hypertension. METHODS:Systematic review without language restriction based on electronic databases, with manual review of literature and conference proceedings until July 2010. Studies we...
journal_title：Intensive care medicine
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00134-011-2224-2
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of different infusion pump models on continuity of drug delivery during vertical displacement of syringe pumps. DESIGN:Zero-drug delivery time (ZDDT), retrograde aspiration volume, and infusion bolus were recorded using the same syringe in three different models of syringe pump after l...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340000784
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVE:The long-term mortality outcome associated with sepsis and septic shock has not been well defined in a nonselected critically ill population. This study investigated the occurrence and the role of bloodstream infection (BSI) associated sepsis and septic shock at time of intensive care unit (ICU) admission on ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-004-2544-6
更新日期：2005-02-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy of different lung recruitment maneuvers using electric impedance tomography. DESIGN AND SETTING:Experimental study in animal model of acute lung injury in an animal research laboratory. SUBJECTS:Fourteen pigs with saline lavage induced lung injury. INTERVENTIONS:Lung volume, region...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-005-2799-6
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVE:The liver plays a key role in the inflammatory response during major surgery or infection. The influence of age on liver function and hepatic acute phase protein (APP) synthesis should be serially studied in elderly patients undergoing major abdominal surgery. DESIGN AND SETTING:Prospective and descriptive s...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-001-1126-0
更新日期：2001-11-01 00:00:00
abstract：OBJECTIVE:Real-time measurement of stroke volume variation by arterial pulse contour analysis (SVV) is useful in predicting volume responsiveness and monitoring volume therapy in mechanically ventilated patients. This study investigated the influence of the depth of tidal volume (V(t)) on SVV both during the state of f...
journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00134-003-1649-7
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVE:Endotracheal suctioning can cause alveolar collapse and impede ventilation. One reason is the gas flow through a single-lumen endotracheal tube (ETT) provoking a gradient between airway opening and tracheal (P(tr)) pressures. Separately extending the patient tubing limbs of a suitable ventilator into the trac...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-004-2537-5
更新日期：2005-03-01 00:00:00
