Abstract：
OBJECTIVE:To investigate whether the respiratory variation in inferior vena cava diameter (DeltaD(IVC)) could be related to fluid responsiveness in mechanically ventilated patients. DESIGN:Prospective clinical study. SETTING:Medical ICU of a non-university hospital. PATIENTS:Mechanically ventilated patients with septic shock (n=39). INTERVENTIONS:Volume loading with 8 mL/kg of 6% hydroxyethylstarch over 20 min. MEASUREMENTS AND RESULTS:Cardiac output and DeltaD(IVC) were assessed by echography before and immediately after the standardized volume load. Volume loading induced an increase in cardiac output from 5.7+/-2.0 to 6.4+/-1.9 L/min (P<0.001) and a decrease in DeltaD(IVC) from 13.8+/-13.6 vs 5.2+/-5.8% (P<0.001). Sixteen patients responded to volume loading by an increase in cardiac output > or =15% (responders). Before volume loading, the DeltaD(IVC) was greater in responders than in non-responders (25+/-15 vs 6+/-4%, P<0.001), closely correlated with the increase in cardiac output (r=0.82, P<0.001), and a 12% DeltaD(IVC) cut-off value allowed identification of responders with positive and negative predictive values of 93% and 92%, respectively. CONCLUSION:Analysis of DeltaD(IVC) is a simple and non-invasive method to detect fluid responsiveness in mechanically ventilated patients with septic shock.
journal_name
Intensive Care Medjournal_title
Intensive care medicineauthors
Feissel M,Michard F,Faller JP,Teboul JLdoi
10.1007/s00134-004-2233-5keywords:
subject
Has Abstractpub_date
2004-09-01 00:00:00pages
1834-7issue
9eissn
0342-4642issn
1432-1238journal_volume
30pub_type
杂志文章abstract：OBJECTIVE:Fibroproliferation markers like procollagen I predict mortality in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). We sought to determine whether bronchoalveolar lavage fluid (BALF) from patients with lung injury contained mediators that would activate procollagen I promo...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-004-2503-2
更新日期：2005-01-01 00:00:00
abstract：INTRODUCTION:Most anxiolytics and sedative regimens in the intensive care unit (ICU) impair intellectual function, reducing patient autonomy, and often add to patient morbidity. Using an ICU-validated cognitive assessment tool Adapted Cognitive Exam (ACE), we performed a comparison between dexmedetomidine (DEX) and pro...
journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00134-010-1874-9
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVE:Candidemia is increasingly encountered in critically ill patients with a high fatality rate. The available data in the critically ill suggest that patients with prior surgery are at a higher risk than others. However, little is known about candidemia in medical settings. The main goal of this study was to com...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-003-2002-x
更新日期：2003-12-01 00:00:00
abstract：:Physicians are increasingly involved in how their critically ill patients die [72]. The more this happens, the more physicians will have to understand not only how their own backgrounds and biases influence their medical management, but also the cultural and religious backgrounds of the patient and surrogate [72, 73]....
journal_title：Intensive care medicine
pub_type： 杂志文章,评审
doi：10.1007/s001340000641
更新日期：2000-10-01 00:00:00
abstract：PURPOSE:We examined whether influenza vaccination affects 1-year risk of myocardial infarction, stroke, heart failure, pneumonia, and death among intensive care unit (ICU) survivors aged ≥ 65 years. METHODS:Danish Intensive Care Database data on all elderly ( ≥ 65 years) patients hospitalized in Danish ICUs in the per...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-019-05648-4
更新日期：2019-07-01 00:00:00
abstract：RATIONALE:Acute respiratory distress syndrome (ARDS) is frequently associated with hemodynamic instability which appears as the main factor associated with mortality. Shock is driven by pulmonary hypertension, deleterious effects of mechanical ventilation (MV) on right ventricular (RV) function, and associated-sepsis. ...
journal_title：Intensive care medicine
pub_type： 杂志文章,评审
doi：10.1007/s00134-016-4326-3
更新日期：2016-05-01 00:00:00
abstract：PURPOSE:To provide recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza pandemic or mass disaster with a specific focus on essential equipment, pharmaceuticals and supplies. METHODS:Based on a literature review and expert opinion, a Delphi process was use...
journal_title：Intensive care medicine
pub_type： 指南,杂志文章
doi：10.1007/s00134-010-1763-2
更新日期：2010-04-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 杂志文章,评审
doi：10.1007/BF00261492
更新日期：1989-01-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-004-2369-3
更新日期：2005-01-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 杂志文章,多中心研究
doi：10.1007/s00134-013-2973-1
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:To evaluate whether soluble triggering receptor expressed on myeloid cells 1 (sTREM-1) in CSF can serve as a biomarker for the presence of bacterial meningitis and outcome in patients with this disease. DESIGN:Retrospective study of diagnostic accuracy. SETTING AND PATIENTS:CSF was collected from 92 adults ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-006-0240-4
更新日期：2006-08-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340050534
更新日期：1998-02-01 00:00:00
abstract：OBJECTIVE:The aim of the present study was (1) to determine the prevalence of intensive care unit (ICU) admissions due to an adverse drug reaction (ADR), and (2) to compare affected patients with patients admitted to the ICU for the treatment of deliberate self-poisoning using medical drugs. DESIGN:Prospective observa...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-008-1250-1
更新日期：2009-02-01 00:00:00
abstract：PURPOSE:Bioactive NO carriers in circulating blood formed during NO inhalation selectively distribute blood flow to areas in need, and may thus improve collateral perfusion to the area-at-risk in acute myocardial infarction (AMI). Here, we tested the hypothesis that NO inhalation during the ischemic phase of AMI may im...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-012-2605-1
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVE:To study the pharmacokinetics and local tissue effects resulting from the intratracheal administration of preservative-free fentanyl. DESIGN:Prospective, randomized, blinded and controlled animal study. SETTING:University research laboratory. SUBJECTS:Eighteen adult male New Zealand rabbits. INTERVENTIONS...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01720719
更新日期：1996-02-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 杂志文章,meta分析,实务指引,评审
doi：10.1007/s00134-016-4665-0
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:Five commercially available oesophageal balloon catheters (OBCs) were tested to evaluate the accuracy in transmitting fast-changing pressure signals which can be observed, for example, during phrenic nerve stimulation. SETTING:Research laboratory of a university hospital. METHOD:The OBCs tested varied in le...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340051182
更新日期：2000-04-01 00:00:00
abstract：:A study was conducted to evaluate repeated intrathecal injections of baclofen, without artificial ventilation, in the treatment of severe tetanus. Ten patients, 5 men and 5 women, with a mean age of 34 +/- 7 years, were included in the study. The dose of baclofen injected was 1000 micrograms between the ages of 16 and...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01709840
更新日期：1992-01-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-006-0519-5
更新日期：2007-03-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF00254705
更新日期：1987-01-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2001-09-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 杂志文章,评审
doi：10.1007/BF01709700
更新日期：1990-01-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章
doi：10.1007/BF01712175
更新日期：1996-05-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章
doi：10.1007/s001340050419
更新日期：1997-08-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章
doi：10.1007/BF01712235
更新日期：1996-03-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 杂志文章,多中心研究
doi：10.1007/s00134-012-2474-7
更新日期：2012-04-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF00256963
更新日期：1988-01-01 00:00:00
abstract：:Specific regulations regarding oversight of research in children vary from country to country, but most share common principles derived from major consensus documents. Whereas the permissibility of research on adults depends heavily upon the informed consent of the subject, the regulation of research in pediatrics is ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-007-0917-3
更新日期：2008-01-01 00:00:00
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journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-013-3133-3
更新日期：2014-01-01 00:00:00
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更新日期：2005-08-01 00:00:00
