Variability of cortisol assays can confound the diagnosis of adrenal insufficiency in the critically ill population.

abstract：OBJECTIVE:To investigate whether ultrasound determination of the inferior vena cava diameter (IVCD) and its collapsibility index (IVCCI) could be used to optimize the fluid removal rate while avoiding hypotension during slow continuous ultrafiltration (SCUF). METHODS:Twenty-four consecutive patients [13 men and 11 wom...

journal_title：Intensive care medicine

authors： Guiotto G,Masarone M,Paladino F,Ruggiero E,Scott S,Verde S,Schiraldi F

更新日期：2010-04-01 00:00:00

abstract：:Hepatic encephalopathy is a complex neuropsychiatric syndrome associated with acute, subacute and chronic liver failure, involving increased neural inhibition by activation of the GABA/benzodiazepine inhibitory neurotransmitter system. Improvement by GABA and benzodiazepine receptor antagonists as well as by chloride ...

journal_title：Intensive care medicine

authors： Gyr K,Meier R

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:Biomarkers allowing accurate early staging of septic shock patients are lacking despite their obvious interest for patient management. Experimental models of septic shock in mouse previously noted a decrease in dendritic cell numbers. The aim of the study was to find a rapid reproducible biological test for a...

journal_title：Intensive care medicine

authors： Guisset O,Dilhuydy MS,Thiébaut R,Lefèvre J,Camou F,Sarrat A,Gabinski C,Moreau JF,Blanco P

更新日期：2007-01-01 00:00:00

abstract：:Two patients with severe hepatic and renal failure underwent emergency hepatic retransplantation (2nd and 6th day after transplantation). Continuous arteriovenous haemodialysis was begun before surgery and successfully performed, without any incident, during the retransplantation with a biospal (SCU/CAVH AN 69 S) devi...

journal_title：Intensive care medicine

authors： Salord F,Bailly MP,Gaussorgues P,Workineh S,Pouyet M,Robert D

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was (1) to determine the prevalence of intensive care unit (ICU) admissions due to an adverse drug reaction (ADR), and (2) to compare affected patients with patients admitted to the ICU for the treatment of deliberate self-poisoning using medical drugs. DESIGN:Prospective observa...

journal_title：Intensive care medicine

authors： Schwake L,Wollenschläger I,Stremmel W,Encke J

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:We tested the hypothesis that synchronization to patient effort during intermittent mandatory ventilation (SIMV), when compared to conventional unsynchronized intermittent mandatory ventilation (IMV), will decrease energy expenditure, as reflected by decreased oxygen consumption (VO2). DESIGN:We used a four-...

journal_title：Intensive care medicine

authors： Smith KM,Wahlig TM,Bing DR,Georgieff MK,Boros SJ,Mammel MC

更新日期：1997-04-01 00:00:00

abstract：PURPOSE:Clinical examination is often the first step to diagnose shock and estimate cardiac index. In the Simple Intensive Care Studies-I, we assessed the association and diagnostic performance of clinical signs for estimation of cardiac index in critically ill patients. METHODS:In this prospective, single-centre coho...

journal_title：Intensive care medicine

authors： Hiemstra B,Koster G,Wiersema R,Hummel YM,van der Harst P,Snieder H,Eck RJ,Kaufmann T,Scheeren TWL,Perner A,Wetterslev J,de Smet AMGA,Keus F,van der Horst ICC,SICS Study Group.

更新日期：2019-02-01 00:00:00

abstract：:We examined the incidence, diagnosis and therapy of acute adrenal insufficiency, secondary to adrenal hemorrhage. This insufficiency resulted in temperature irregularities. hemodynamic instability, and a large volume resuscitation requirement post-operatively. The case illustrates that a high level of suspicion should...

journal_title：Intensive care medicine

authors： Szalados JE,Vukmir RB

更新日期：1994-01-01 00:00:00

abstract：:Nosocomial pneumonia continues to represent a significant cause of morbidity and mortality in hospitalized patients. Bacteria are responsible for greater than 90% of the pneumonias, the most common isolates being aerobic Gram-negative bacilli and S. aureus. Cornerstones of treatment are intravenous antibiotics and sup...

journal_title：Intensive care medicine

authors： Unertl KE,Lenhart FP,Forst H,Peter K

更新日期：1992-01-01 00:00:00

abstract：:There has been little research on smoking cessation after critical illness. Smokers make up a high percentage of patients admitted to intensive care (ICU) and stopping smoking is one message that should be clearly given to recovering patients. The recovery period provides an important opportunity for patients to quit ...

journal_title：Intensive care medicine

authors： Jones C,Griffiths RD,Skirrow P,Humphris G

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:To assess the effects of the cyclooxygenase inhibitor diclofenac in a canine model of pulmonary occlusion and reperfusion of the left lower lobe (LLL). DESIGN:Twelve adult beagle dogs (13-17 kg) were randomly assigned to a control group (n = 6) and a diclofenac-treated group (n = 6). Animals in the treatment...

journal_title：Intensive care medicine

authors： Segiet W,Krieter H,Stieber C,Albrecht DM,van Ackern K

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:To investigate the theoretical interactions between ventilator settings, tracheal gas insufflation (TGI), and alveolar ventilation. DESIGN:We derived differential equations governing compartmental volume changes in a one-compartment model of TGI-assisted ventilation and equations governing gas dilution in th...

journal_title：Intensive care medicine

authors： Hotchkiss JR Jr,Crooke PS 3rd,Marini JJ

更新日期：1996-10-01 00:00:00

abstract：:This report identifies some of the risk factors underlying the acquisition of hospital infections in patients admitted to Intensive Care Units (ICUs). Infection rates vary in different institutes and in different types of ICUs. Patients are particularly prone to septicaemia and respiratory infections and the underlyin...

journal_title：Intensive care medicine

authors： Emmerson AM

更新日期：1990-01-01 00:00:00

abstract：:The process of surgical decision making is based on both general principles that are amenable to evaluation using rigorous techniques of clinical research and the intangible element of surgical judgment that seeks to apply those principles to the care of an individual patient. The role of surgical judgment is inescapa...

journal_title：Intensive care medicine

authors： Jimenez MF,Marshall JC,International Sepsis Forum.

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:Septic shock-induced disseminated intravascular coagulopathy (DIC) contributes to multiple organ failure. Mechanisms governing vascular responses to open occurrence of DIC have not yet been established. Circulating plasma microparticles (MPs), released upon cell stress, constitute a catalytic procoagulant surfa...

journal_title：Intensive care medicine

authors： Delabranche X,Boisramé-Helms J,Asfar P,Berger A,Mootien Y,Lavigne T,Grunebaum L,Lanza F,Gachet C,Freyssinet JM,Toti F,Meziani F

更新日期：2013-10-01 00:00:00

abstract：:Placement of a Swan-Ganz catheter can cause many complications. This case report presents a new complication of Swan-Ganz catheter insertion--placement of the Swan-Ganz catheter tip in the coronary sinus. ...

journal_title：Intensive care medicine

authors： Baciewicz FA,Nirdlinger MA,Davis JT

更新日期：1987-01-01 00:00:00

abstract：:We report the intensive care management of 23 children (age 3-15 years) following orthotopic heart (HT) and combined heart and lung transplantation (HLT) performed at our 2 institutes between February 1985 and August 1989. Cyclosporin A, azathioprine and steroids were given as routine immunosuppression, whilst anti-th...

journal_title：Intensive care medicine

authors： Whitehead B,James I,Helms P,Scott JP,Smyth R,Higenbottam TW,McGoldrick J,English TA,Wallwork J,Elliott M

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:Adverse respiratory and gasometrical effects have been described in patients with acute respiratory failure (ARF) undergoing noninvasive ventilation (NIV) with standard heat and moisture exchangers (HME). We decided to evaluate respiratory parameters and arterial blood gases (ABG) of patients during NIV with ...

journal_title：Intensive care medicine

authors： Boyer A,Vargas F,Hilbert G,Gruson D,Mousset-Hovaere M,Castaing Y,Dreyfuss D,Ricard JD

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To compare outcome prediction using the Multiple Organ Dysfunction Score (MODS) and the Sequential Organ Failure Assessment (SOFA), two of the systems most commonly used to evaluate organ dysfunction in the intensive care unit (ICU). DESIGN:Prospective, observational study. SETTING:Thirty-one-bed, universit...

journal_title：Intensive care medicine

authors： Peres Bota D,Melot C,Lopes Ferreira F,Nguyen Ba V,Vincent JL

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:The liver plays a key role in the inflammatory response during major surgery or infection. The influence of age on liver function and hepatic acute phase protein (APP) synthesis should be serially studied in elderly patients undergoing major abdominal surgery. DESIGN AND SETTING:Prospective and descriptive s...

journal_title：Intensive care medicine

authors： Suttner SW,Sürder C,Lang K,Piper SN,Kumle B,Boldt J

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the origin of H+ ions participating in the generation of CO2 coming from sodium bicarbonate infusion during metabolic acidosis. We hypothesized that these H+ ions come from a back-titration of the main non-bicarbonate buffers present in the blood, i. e. the hemoglobin and the albumin, and thus pos...

journal_title：Intensive care medicine

authors： Levraut J,Garcia P,Giunti C,Ichai C,Bouregba M,Ciebiera JP,Payan P,Grimaud D

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:To determine the value of procalcitonin (PCT) in the early diagnosis (and differentiation) of patients with SIRS, sepsis, severe sepsis, and septic shock in comparison to C-reactive protein (CRP), white blood cell and thrombocyte count, and APACHE-II score (AP-II). DESIGN:Prospective cohort study including a...

journal_title：Intensive care medicine

authors： Brunkhorst FM,Wegscheider K,Forycki ZF,Brunkhorst R

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:To study the influence of continuous administration of heparin on platelet function in intensive care patients. DESIGN:Prospective, serial investigation. SETTING:Clinical investigation on a surgical and neurosurgical intensive care unit in a university hospital. PATIENTS:The study included 45 patients: 15 ...

journal_title：Intensive care medicine

authors： Boldt J,Müller M,Rothe A,Lenzen P,Hempelmann G

更新日期：1997-05-01 00:00:00

abstract：PURPOSE:Plasma immunoglobulin concentrations are acutely altered in critically ill patients with sepsis. However, the association between immunoglobulin levels on the day of sepsis diagnosis and subsequent mortality is inconsistent. METHODS:Systematic review of studies that report immunoglobulin measurements and morta...

journal_title：Intensive care medicine

authors： Shankar-Hari M,Culshaw N,Post B,Tamayo E,Andaluz-Ojeda D,Bermejo-Martín JF,Dietz S,Werdan K,Beale R,Spencer J,Singer M

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To determine: (1) the proportion of small (<5 mm) or thrombosed internal jugular veins (IJV) and femoral veins (FV) in which catheter placement would be difficult without ultrasound guidance; (2) which position increases central vein sizes and may facilitate cannulation of these vessels. DESIGN:Prospective s...

journal_title：Intensive care medicine

authors： Samy Modeliar S,Sevestre MA,de Cagny B,Slama M

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:The Guillain-Barré syndrome (GBS) is an acute inflammatory polyneuropathy related to autoimmunity. However, no conclusive etiological concept has yet been found. We examined the variation in autoantibodies to lipids in serum of GBS patients in response to the course of the disease but investigated titer modif...

journal_title：Intensive care medicine

authors： Nakos G,Tziakou E,Maneta-Peyret L,Nassis C,Lekka ME

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:Percutaneous dilatational tracheostomy is increasingly practiced in intensive care units and has a low incidence of early complications. The late effects of this procedure are still poorly known and were the focus of this study. DESIGN:Prospective descriptive clinical study. SETTING:Interdisciplinary intens...

journal_title：Intensive care medicine

authors： Fischler MP,Kuhn M,Cantieni R,Frutiger A

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:The immediate overwhelming release of inflammatory mediators in septic shock is rapidly followed by strong anti-inflammatory responses inducing a state of immunosuppression. The patients who survive the initial hyper-inflammatory step of septic shock but subsequently die may be those who do not recover from i...

journal_title：Intensive care medicine

authors： Monneret G,Lepape A,Voirin N,Bohé J,Venet F,Debard AL,Thizy H,Bienvenu J,Gueyffier F,Vanhems P

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:This study assessed parameters of free radical damage to biomolecules, mitochondrial superoxide production, superoxide dismutase, and catalase activities and their relationship to sepsis mortality. DESIGN AND SETTING:Prospective animal study in a university laboratory for experimental. SUBJECTS:140 male Wis...

journal_title：Intensive care medicine

authors： Ritter C,Andrades M,Frota Júnior ML,Bonatto F,Pinho RA,Polydoro M,Klamt F,Pinheiro CT,Menna-Barreto SS,Moreira JC,Dal-Pizzol F

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficiency of a new device developed to remove obstructions from endotracheal tubes (ETT) in mechanically ventilated patients. DESIGN:Open study in mechanically ventilated sedated and paralyzed ICU patients. SETTING:General ICU and Laboratory of Respiratory Mechanics of the University of Rom...

journal_title：Intensive care medicine

authors： Conti G,Rocco M,De Blasi RA,Lappa A,Antonelli M,Bufi M,Gasparetto A

更新日期：1994-11-01 00:00:00