Monitoring of neuromuscular blockade: a comparison of train-of-four and the Campbell diagram.

abstract：INTRODUCTION:A prospective physiological study was performed in 12 paediatric patients with acute moderate hypercapnic respiratory insufficiency to assess the ability of noninvasive positive pressure ventilation (NPPV) to unload the respiratory muscles and improve gas exchange. MATERIALS AND METHODS:Breathing pattern,...

journal_title：Intensive care medicine

authors： Essouri S,Durand P,Chevret L,Haas V,Perot C,Clement A,Devictor D,Fauroux B

更新日期：2008-12-01 00:00:00

abstract：:The increase of the inflationary lung volume created by a respiratory maneuver is critical for preventing postoperative alveolar collapse. We measured this volume as achieved with IPPB or incentive spirometry (IS) in 20 postoperative surgical patients. Using IPPB, with gas flow and peak airway pressures carefully adju...

journal_title：Intensive care medicine

authors： Pfenninger J,Roth F

更新日期：1977-12-01 00:00:00

abstract：PURPOSE:Computerized clinical decision support systems (CDSS) for intensive insulin therapy (IIT) generate recommendations using blood glucose (BG) values manually transcribed from testing devices to computers, a potential source of error. We quantified the frequency and effect of blood glucose transcription mismatches...

journal_title：Intensive care medicine

authors： Campion TR Jr,May AK,Waitman LR,Ozdas A,Gadd CS

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Inhalation of nitric oxide (NO) can improve oxygenation and decrease mean pulmonary artery pressure (MPAP) in patients with the acute respiratory distress syndrome (ARDS). It is not known whether inhaled NO exerts a similar effect in hypoxemic patients with chronic obstructive pulmonary disease (COPD). DESIG...

journal_title：Intensive care medicine

authors： Blanch L,Joseph D,Fernández R,Mas A,Martinez M,Vallés J,Diaz E,Baigorri F,Artigas A

更新日期：1997-01-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Monnet X,Saugel B

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:To determine the steady-state trough serum and epithelial lining fluid (ELF) concentrations of teicoplanin 12 mg/kg per day in critically ill patients with ventilator associated pneumonia. DESIGN AND SETTING:Prospective, pharmacokinetic study in the surgical intensive care unit in a university hospital. PAT...

journal_title：Intensive care medicine

authors： Mimoz O,Rolland D,Adoun M,Marchand S,Breilh D,Brumpt I,Debaene B,Couet W

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:An investigation into the incidence of post-operative complications after thoracic surgery with 3 different physiotherapy masks. DESIGN:A prospective, consecutive, randomized comparison. SETTING:Department of Thoracic and Heart Surgery at a University Hospital. The treatments were performed by experienced a...

journal_title：Intensive care medicine

authors： Ingwersen UM,Larsen KR,Bertelsen MT,Kiil-Nielsen K,Laub M,Sandermann J,Bach K,Hansen H

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:Pressure measurements at the level of the right atrium are commonly used in clinical anesthesia and the intensive care unit (ICU). There is growing interest in the use of peripheral venous sites for estimating central venous pressure (CVP). This study compared bias, precision, and covariance in simultaneous m...

journal_title：Intensive care medicine

authors： Desjardins R,Denault AY,Bélisle S,Carrier M,Babin D,Lévesque S,Martineau R

更新日期：2004-04-01 00:00:00

abstract：PURPOSE:Evidence of variation in mortality after surgery may indicate preventable postoperative death. We sought to determine if regional differences in outcome were present in surgical patients admitted to critical care in the UK. METHODS:We extracted data on admission characteristics, case mix and outcome of all pat...

journal_title：Intensive care medicine

authors： Gillies MA,Power GS,Harrison DA,Fleming A,Cook B,Walsh TS,Pearse RM,Rowan KM

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:Erythrocytes influence the magnitude of hypoxia-induced pulmonary artery pressure increase. It is, however, unknown to what extent haemoconcentration and haemodilution affect this response and whether intrapulmonary blood volume (and thus vessel dimensions) alters the magnitude of pressure increase. Furthermo...

journal_title：Intensive care medicine

authors： Loer SA,Peters J

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To assess the impact of hemodynamic variables on the outcome of critically ill patients in septic shock and to identify the optimal threshold values related to outcome with special reference to continuously monitored mean arterial pressure (MAP) and mixed venous oxygen saturation (SvO2). DESIGN AND SETTING:R...

journal_title：Intensive care medicine

authors： Varpula M,Tallgren M,Saukkonen K,Voipio-Pulkki LM,Pettilä V

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:The evaluation of incidences and relating factors of severe persisting critical illness polyneuropathy (CIP) in survivors of multiple organ failure (MOF). DESIGN:Prospective study with an entry period of 24 months. Electrophysiological studies for the diagnosis of CIP were performed 1 or 2 days before the pa...

journal_title：Intensive care medicine

authors： Mohr M,Englisch L,Roth A,Burchardi H,Zielmann S

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the usefulness of early transcranial Doppler ultrasound (TCD) goal-directed therapy after severe traumatic brain injury initiated before invasive cerebral monitoring is available. DESIGN:Prospective, observational clinical study. SETTING:Surgical intensive care unit, university hospital. PATIEN...

journal_title：Intensive care medicine

authors： Ract C,Le Moigno S,Bruder N,Vigué B

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:To develop a liver function-related risk prediction tool to identify acute-on-chronic liver failure patients at greatest risk of in-hospital mortality. METHODS:The LiFe (liver, injury, failure, evaluation) score, was constructed based on the opinions of 157 intensivists within the European Society for Intensiv...

journal_title：Intensive care medicine

authors： Edmark C,McPhail MJW,Bell M,Whitehouse T,Wendon J,Christopher KB

更新日期：2016-03-01 00:00:00

abstract：:Sixteen anaesthetized rabbits were subjected to tracheostomy and lung damage produced by the instillation of 4.5 ml/kg hydrochloric acid (pH 1.5) into the trachea. Half of the animals were ventilated with a positive end-expiratory pressure (PEEP) of 3 cmH2O and half with a PEEP of 10 cmH2O for 5 h, the mean airway pre...

journal_title：Intensive care medicine

authors： Sohma A,Brampton WJ,Dunnill MS,Sykes MK

更新日期：1992-01-01 00:00:00

abstract：UNLABELLED:Admission of cancer patients with serious medical complications to the ICU remains controversial primarily because of the high short-term mortality rates in these patients. However, the cancer patient population is heterogeneous regarding age, underlying conditions, and curability of their disease, suggestin...

journal_title：Intensive care medicine

authors： Azoulay E,Moreau D,Alberti C,Leleu G,Adrie C,Barboteu M,Cottu P,Levy V,Le Gall JR,Schlemmer B

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:Evaluating the prevalence, risk factors and prevention of pressure ulcers in Dutch intensive care units (ICUs). DESIGN:Cross-sectional design. SETTING:ICUs of acute care hospitals that participated in the 1998 and 1999 national prevalence surveys. Data were collected on 1 day in each year. PATIENTS:Eight h...

journal_title：Intensive care medicine

authors： Bours GJ,De Laat E,Halfens RJ,Lubbers M

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:To evaluate major similarities and major differences between Western European countries in intensive care unit (ICU) nurse staffing, education, training, responsibilities, and initiative. DESIGN:A questionnaire was sent to Western European doctor members of the European Society of Intensive Care Medicine, to...

journal_title：Intensive care medicine

authors： Depasse B,Pauwels D,Somers Y,Vincent JL

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:Antipyrine metabolism is a "gold standard" measure of mixed cytochrome P450 (CYP) mediated drug metabolism in humans. Cytokines (e.g., interleukin-6) and nitric oxide reduce CYP 450 activity in vitro and in vivo. Because interleukin-6 and nitric oxide production increases in children with sepsis-induced multi...

journal_title：Intensive care medicine

authors： Carcillo JA,Doughty L,Kofos D,Frye RF,Kaplan SS,Sasser H,Burckart GJ

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:Controversy over the optimal intravenous fluid for volume resuscitation continues unabated. Our objectives were to characterize the demographics of physicians who prescribe intravenous colloids and determine factors that enter into their decision to choose a colloid. DESIGN:Questionnaire with 61 items. PAR...

journal_title：Intensive care medicine

authors： Miletin MS,Stewart TE,Norton PG

更新日期：2002-07-01 00:00:00

abstract：:Plasma colloid osmotic pressure (COP) has been calculated from both serum albumin concentration and plasma total protein concentration. These values have been compared to those measured directly using a membrane-transducer oncometer in a group of normal subjects, in a group of critically-ill patients with a variety of...

journal_title：Intensive care medicine

authors： Barclay SA,Bennett D

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:Assessing feasibility and physiological effects of sedation with sevoflurane, administered with the anesthetic conserving device (AnaConDa), in comparison with propofol and remifentanil. METHODS:Seventeen patients undergoing mechanical ventilation underwent sedation with sevoflurane delivered with AnaConDa (ph...

journal_title：Intensive care medicine

authors： Migliari M,Bellani G,Rona R,Isgrò S,Vergnano B,Mauri T,Patroniti N,Pesenti A,Foti G

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the use of antidotal therapy in patients with an elevated digitalis concentration following chronic or acute exposure. DESIGN AND SETTING:Retrospective review of patient records over 2 years in 20 city hospitals in France. PATIENTS:Overall 838 patients with an elevated serum digitalis concentrat...

journal_title：Intensive care medicine

authors： Lapostolle F,Borron SW,Verdier C,Arnaud F,Couvreur J,Mégarbane B,Baud F,Adnet F

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:Severe acute pancreatitis (SAP) remains a life-threatening disease with classic etiology of systemic inflammatory response and mortality between 30 and 50 %. The aim of the present study is to compare two different treatment strategies of goal-directed hemodynamic management and evaluate their impact on surviva...

journal_title：Intensive care medicine

authors： Trepte CJ,Bachmann KA,Stork JH,Friedheim TJ,Hinsch A,Goepfert MS,Mann O,Izbicki JR,Goetz AE,Reuter DA

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Early central venous catheter (CVC) insertion in Ebola virus disease (EVD) is a novel approach and has not previously been described. This report delineates the safety, feasibility and clinical implications of early CVC insertion as the optimum means of vascular access in patients with EVD, in the setting of a ...

journal_title：Intensive care medicine

authors： Rees PS,Lamb LE,Nicholson-Roberts TC,Ardley CN,Bailey MS,Hinsley DE,Fletcher TE,Dickson SJ

更新日期：2015-05-01 00:00:00

abstract：:Hemorrhagic complications from transection of cervical arteries in blunt traumas are rare. We report a case of potentially fatal hemorrhage from rupture of the left vertebral artery in a closed trauma, successfully treated by endovascular injection of glue. Endovascular embolization may be considered as an alternative...

journal_title：Intensive care medicine

authors： Simionato F,Righi C,Silvani P,Torri G,Scotti G

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:To investigate the accuracy of lung ultrasonography (LUS) in the quantification of lung water in critically ill patients by using quantitative computed tomography (CT) as the gold standard for the determination of lung weight. METHODS:Twenty consecutive patients admitted to an intensive care unit who underwe...

journal_title：Intensive care medicine

authors： Baldi G,Gargani L,Abramo A,D'Errico L,Caramella D,Picano E,Giunta F,Forfori F

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:The clinical significance of septic myocardial dysfunction is controversial, a fact that may be explained by the influence of loading conditions. Many indices may be useful to characterize cardiac function during septic shock, but their feasibility and physiological coherence in the clinical setting are unknown...

journal_title：Intensive care medicine

authors： Boissier F,Razazi K,Seemann A,Bedet A,Thille AW,de Prost N,Lim P,Brun-Buisson C,Mekontso Dessap A

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:We perform an ethical analysis of European Union Directive 2001/20/EC on the simplification and harmonization of guidelines regarding good clinical practice in the conduct of clinical trials involving drugs. BACKGROUND:The Directive provides guidance on protecting incapacitated subjects who participate in dr...

journal_title：Intensive care medicine

authors： Silverman HJ,Druml C,Lemaire F,Nelson R,European Union Directive.

更新日期：2004-09-01 00:00:00

abstract：:The endothelium is a highly dynamic cell layer that is involved in a multitude of physiological functions, including the control of vascular tone, the movement of cells and nutrients, the maintenance of blood fluidity and the growth of new vessels. During severe sepsis, the endothelium becomes proadhesive, procoagulan...

journal_title：Intensive care medicine

authors： Ait-Oufella H,Maury E,Lehoux S,Guidet B,Offenstadt G

更新日期：2010-08-01 00:00:00