Microalbuminuria does not reflect increased systemic capillary permeability in septic shock.

abstract：OBJECTIVE:To assess the safety and efficacy of sustained inflations (SI) as lung recruitment maneuvers (RMs) in ventilated pediatric intensive care unit (PICU) patients. DESIGN:Observational, prospective data collection. SETTING:Tertiary-care PICU. PATIENTS AND PARTICIPANTS:Thirty-two consecutive ventilated pediatri...

journal_title：Intensive care medicine

authors： Duff JP,Rosychuk RJ,Joffe AR

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of two different comorbidity measures on the 6-month mortality of severely ill cancer patients. DESIGN AND SETTING:Prospective cohort study in a ten-bed oncological medical-surgical intensive care unit (ICU). PATIENTS:A total of 772 consecutive patients were included over a 45-month p...

journal_title：Intensive care medicine

authors： Soares M,Salluh JI,Ferreira CG,Luiz RR,Spector N,Rocco JR

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:This study compared the recently introduced Microcuff endotracheal tube HVLP ICU featuring an ultrathin (7-microm) polyurethane cuff membrane with endotracheal tubes from different manufacturers regarding fluid leakage past the tube cuff. DESIGN:In vitro setup. MEASUREMENTS AND RESULTS:The following endotra...

journal_title：Intensive care medicine

authors： Dullenkopf A,Gerber A,Weiss M

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To evaluate trends in mortality and related factors among trauma patients who developed acute respiratory distress syndrome (ARDS). STUDY:Observational study based on data prospectively gathered in computerized trauma registry. SETTING:Trauma intensive care unit (ICU) of 48 beds in level I trauma center. P...

journal_title：Intensive care medicine

authors： Navarrete-Navarro P,Rodriguez A,Reynolds N,West R,Habashi N,Rivera R,Chiu WC,Scalea T

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Ornithine alpha-ketoglutarate (OKG) has proved to be efficient in restoring glutamine (Gln) pools which are strongly depleted in hypercatabolic patients. Since its two components, alpha-ketoglutarate (alphaKG) and ornithine (Orn), give rise to glutamate (Glu), they are both considered as Gln precursors. The ...

journal_title：Intensive care medicine

authors： Cynober L,Lasnier E,Le Boucher J,Jardel A,Coudray-Lucas C

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:To study the incidence and clinical characteristics of delayed cerebral thrombosis in bacterial meningitis patients. METHODS:We assessed the incidence and clinical characteristics of delayed cerebral thrombosis in adults with cerebrospinal fluid (CSF) culture-proven community-acquired bacterial meningitis incl...

journal_title：Intensive care medicine

authors： Lucas MJ,Brouwer MC,van de Beek D

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:There are a number of potential etiologies of severe bleeding encountered in the intensive care unit. Although rare, acquired hemophilia is one such etiology that often presents with major bleeding requiring intensive care. Despite the introduction of effective treatments, the reported mortality rate of patie...

journal_title：Intensive care medicine

authors： Shander A,Walsh CE,Cromwell C

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:To measure water balance and changes in distribution, and the effect of giving supplementary albumin, early after a burn injury. DESIGN:Consecutive patients (matched groups) and healthy controls. SETTING:National burn unit in a Swedish university hospital. PATIENTS AND SUBJECTS:Eighteen patients with 18%-9...

journal_title：Intensive care medicine

authors： Zdolsek HJ,Lisander B,Jones AW,Sjöberg F

更新日期：2001-05-01 00:00:00

abstract：PURPOSE:The use of heat and moisture exchangers (HME) during noninvasive ventilation (NIV) can increase the work of breathing, decrease alveolar ventilation, and deliver less humidity in comparison with heated humidifiers (HH). We tested the hypothesis that the use of HH during NIV with ICU ventilators for patients wit...

journal_title：Intensive care medicine

authors： Lellouche F,L'Her E,Abroug F,Deye N,Rodriguez PO,Rabbat A,Jaber S,Fartoukh M,Conti G,Cracco C,Richard JC,Ricard JD,Mal H,Mentec H,Loisel F,Lacherade JC,Taillé S,Brochard L

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:To compare the concentration conformity of infusion solutions manually prepared on intensive care units (ICU) with solutions from pharmacy-based, automated production. METHODS:A prospective observational study conducted in a university hospital in Germany. Drug concentrations of 100 standardised infusion solut...

journal_title：Intensive care medicine

authors： Dehmel C,Braune SA,Kreymann G,Baehr M,Langebrake C,Hilgarth H,Nierhaus A,Dartsch DC,Kluge S

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:Children with peripheral airways obstruction suffer the negative effects of intrinsic positive end-expiratory pressure: increased work of breathing and difficulty triggering assisted ventilatory support. We examined whether external positive end-expiratory pressure to offset intrinsic positive end-expiratory...

journal_title：Intensive care medicine

authors： Graham AS,Chandrashekharaiah G,Citak A,Wetzel RC,Newth CJ

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:The Pediatric Index of Mortality 2 (PIM2), one of the key mortality prediction models for children in intensive care units, has not been validated in Japan. The purpose of this study was to validate the performance of PIM2 in a population of patients admitted to one pediatric intensive care unit (PICU) in Jap...

journal_title：Intensive care medicine

authors： Imamura T,Nakagawa S,Goldman RD,Fujiwara T

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:(a) To measure gastric tonometry values in critically ill patients with peritonitis and to assess the impact of epidural analgesia on these values. (b) To assess the impact of epidural analgesia on gastro-intestinal motility by abdominal ultrasound and paracetamol absorption. (c) To observe any change in cli...

journal_title：Intensive care medicine

authors： Spackman DR,McLeod AD,Prineas SN,Leach RM,Reynolds F

更新日期：2000-11-01 00:00:00

abstract：:Extracorporeal life support (ECLS) can support gas exchange in patients with the acute respiratory distress syndrome (ARDS). During ECLS, venous blood is drained from a central vein via a cannula, pumped through a semipermeable membrane that permits diffusion of oxygen and carbon dioxide, and returned via a cannula to...

journal_title：Intensive care medicine

authors： Combes A,Schmidt M,Hodgson CL,Fan E,Ferguson ND,Fraser JF,Jaber S,Pesenti A,Ranieri M,Rowan K,Shekar K,Slutsky AS,Brodie D

更新日期：2020-12-01 00:00:00

abstract：:In a randomized clinical trial the prophylactic effects of locally administered antimicrobials on quantitative colonization and respiratory infections were studied in intubated patients with an expected period of mechanical ventilation of greater than 6 days. Nineteen patients received 50 mg of polymyxin B and 80 mg o...

journal_title：Intensive care medicine

authors： Unertl K,Ruckdeschel G,Selbmann HK,Jensen U,Forst H,Lenhart FP,Peter K

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:Invasive candidiasis (IC) outcomes in intensive care units (ICUs) could be improved by the early administration of antifungals. The Candida Score (CS) prediction rule has been proposed for the selection of patients who could develop IC. Procalcitonin (PCT) levels allow prompt identification of sepsis, but the...

journal_title：Intensive care medicine

authors： Charles PE,Castro C,Ruiz-Santana S,León C,Saavedra P,Martín E

更新日期：2009-12-01 00:00:00

abstract：:During a 3-year period, a clinical diagnosis of invasive candidosis was made in 8 out of 2054 consecutive surgical intensive care unit (ICU) patients. These patients were retrospectively matched with 16 control patients who underwent similar surgical procedures and had a similar clinical course except for negative Can...

journal_title：Intensive care medicine

authors： Lepper PM,Wiedeck H,Geldner G,Essig A,Trautmann M

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:To study whether transient hyperglycemia adversely affects cerebral energy metabolism in patients with severe traumatic brain lesions. DESIGN AND SETTING:Prospective, nonrandomized study in the neurosurgical intensive care unit of a university hospital. PATIENTS:108 patients treated for severe traumatic bra...

journal_title：Intensive care medicine

authors： Diaz-Parejo P,Ståhl N,Xu W,Reinstrup P,Ungerstedt U,Nordström CH

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:We examined whether early diffusion-weighted magnetic resonance imaging (DW-MRI) abnormalities of the brain and variation of apparent diffusion coefficient (ADC) values can provide prognostic information on clinical outcome in children following cardiac arrest (CA). DESIGN:Retrospective study. SETTING:A 12-...

journal_title：Intensive care medicine

authors： Oualha M,Gatterre P,Boddaert N,Dupic L,De Saint Blanquat L,Hubert P,Lesage F,Desguerre I

更新日期：2013-07-01 00:00:00

abstract：:In severe status asthmaticus basic medical treatment often fails to improve the patient's condition. Mechanical ventilation in this situation is associated with a high incidence of serious complications. After the bronchodilating effect of moderate-dose magnesium sulfate in asthmatic patients had been demonstrated in ...

journal_title：Intensive care medicine

authors： Sydow M,Crozier TA,Zielmann S,Radke J,Burchardi H

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:The Sonoclot analyser provides global measurement of haemostasis, including plasma coagulation, platelet function and fibrinolysis. Benefits of its use in cardiovascular and hepatic surgery are well-documented and it may be useful in managing obstetric complications. The aim of this study was to determine ran...

journal_title：Intensive care medicine

authors： Kjellberg U,Hellgren M

更新日期：2000-02-01 00:00:00

abstract：:A 17-year-old patient with Shone's disease had to be readmitted to the hospital 3 months after implantation of an artificial aortic valve because of extreme mitral insufficiency with consecutive pulmonary edema and hepatic dysfunction. He had been orally anticoagulated and presented with a high international normalize...

journal_title：Intensive care medicine

authors： Rauch R,Hofbeck M,Ries M,Singer H,Klinge J

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Adverse respiratory and gasometrical effects have been described in patients with acute respiratory failure (ARF) undergoing noninvasive ventilation (NIV) with standard heat and moisture exchangers (HME). We decided to evaluate respiratory parameters and arterial blood gases (ABG) of patients during NIV with ...

journal_title：Intensive care medicine

authors： Boyer A,Vargas F,Hilbert G,Gruson D,Mousset-Hovaere M,Castaing Y,Dreyfuss D,Ricard JD

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:Definition of the changes in the activators of plasminogen, u-PA and t-PA, and examination of the possible generation of plasmin in the circulation in overwhelming sepsis. DESIGN:Serial blood analysis starting 4 h after development of symptoms of toxic shock syndrome. SETTING:Intensive care unit. PATIENT:A...

journal_title：Intensive care medicine

authors： Haj MA,Robbie LA,Croll A,Adey GD,Bennett B

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:Five commercially available oesophageal balloon catheters (OBCs) were tested to evaluate the accuracy in transmitting fast-changing pressure signals which can be observed, for example, during phrenic nerve stimulation. SETTING:Research laboratory of a university hospital. METHOD:The OBCs tested varied in le...

journal_title：Intensive care medicine

authors： Buscher H,Valta P,Sydow M,Thies K,Burchardi H

更新日期：2000-04-01 00:00:00

abstract：PURPOSE:To determine incidence, risk factors and outcome of tracheal ischemic lesions related to intubation. METHODS:Planned post hoc analysis using patients from a previous randomized controlled study. Fiberoptic tracheoscopy was performed during the 24 h following extubation. In patients with >2 ischemic lesions, ul...

journal_title：Intensive care medicine

authors： Touat L,Fournier C,Ramon P,Salleron J,Durocher A,Nseir S

更新日期：2013-04-01 00:00:00

abstract：:The influence of varying cardiac output (CO) on thermal-dye extravascular lung water (EVLW) was investigated in a total of 40 cardiac surgery patients before the onset of the operation. EVLW was measured by means of the double indicator dilution technique with indocyanine green as the non-diffusible indicator and a mi...

journal_title：Intensive care medicine

authors： Boldt J,Kling D,von Bormann B,Scheld HH,Hempelmann G

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:To measure the effects of rapid permissive hypercapnia on hemodynamics and gas exchange in patients with acute respiratory distress syndrome (ARDS). DESIGN:Prospective study. SETTING:18-bed, medical intensive care unit, university hospital. PATIENTS:11 mechanically ventilated ARDS patients. INTERVENTION:P...

journal_title：Intensive care medicine

authors： Thorens JB,Jolliet P,Ritz M,Chevrolet JC

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:We examined in rabbits the effects of more than 48 h of mechanical ventilation on the contractile properties and fiber type adaptations of the respiratory muscles. DESIGN AND SETTING:Experimental prospective study in a university laboratory. ANIMALS AND INTERVENTIONS:Nineteen rabbits were randomly allocated...

journal_title：Intensive care medicine

authors： Capdevila X,Lopez S,Bernard N,Rabischong E,Ramonatxo M,Martinazzo G,Prefaut C

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:Motivated by a new randomized trial (the PEPTIC trial) that raised the issue of an increase in mortality with proton pump inhibitors (PPIs) relative to histamine-2 receptor antagonists (H2RAs), we updated our prior systematic review and network meta-analysis (NMA) addressing the impact of pharmacological gastro...

journal_title：Intensive care medicine

authors： Wang Y,Ge L,Ye Z,Siemieniuk RA,Reintam Blaser A,Wang X,Perner A,Møller MH,Alhazzani W,Cook D,Guyatt GH

更新日期：2020-11-01 00:00:00