当前位置： SCI文献检索 > INTENSIVE CARE MEDICINE期刊下所有文献 > Acute respiratory distress syndrome among trauma patients: trends in ICU mortality, risk factors, complications and resource utilization.

Acute respiratory distress syndrome among trauma patients: trends in ICU mortality, risk factors, complications and resource utilization.

Abstract：

OBJECTIVE:To evaluate trends in mortality and related factors among trauma patients who developed acute respiratory distress syndrome (ARDS). STUDY:Observational study based on data prospectively gathered in computerized trauma registry. SETTING:Trauma intensive care unit (ICU) of 48 beds in level I trauma center. PATIENTS:All trauma patients with ARDS admitted during 1985-87 (486, group 1 [G1]) and 1993-95 (552, group 2[G2]). METHODS:ARDS was defined by American-European Consensus Conference criteria and the need for 48 h or more on mechanical ventilation with FIO2 greater than 0.50 and PEEP of more than 5 cmH2O. Demographics, severity score, injury-admission delay time, first 24-h transfusion and septic and organ system failure complications were independent variables. ICU mortality was the dependent variable. ICU length of stay (LOS) and life support techniques were considered. Respiratory and renal support strategies were different in the two time periods. RESULTS:Mortality decreased over the period (G1: 29.2% vs G2: 21.4%, p < 0.04), in patients aged both over and under 65 years. Multivariate analysis showed mortality was related to age, severity and time period (G1 1.68-fold that in G2) and that the greater G1 mortality was related to more renal failure and hematologic failure/dysfunction. ICU LOS decreased from 31.7+/-26.7 days (G1) to 27.3+/-22 days (G2) (p < 0.003). CONCLUSIONS:Mortality among trauma patients with ARDS declined over the 8 years studied and was associated with less organ failure. This reduction was probably the result of new approaches to mechanical ventilation, renal failure replacement and vasoactive drug therapy.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Navarrete-Navarro P,Rodriguez A,Reynolds N,West R,Habashi N,Rivera R,Chiu WC,Scalea T

doi

10.1007/s001340100955

keywords:

subject

Has Abstract

pub_date

2001-07-01 00:00:00

pages

1133-40

issue

7

eissn

0342-4642

issn

1432-1238

journal_volume

27

pub_type

杂志文章

相关文献

INTENSIVE CARE MEDICINE文献大全
  • Evaluation of two processed EEG analyzers for assessment of sedation after coronary artery bypass grafting.

    abstract：OBJECTIVES:Processed EEG monitoring has been suggested for sedation depth evaluation in intensive care unit (ICU) patients. The present study investigated the efficacy of two processed EEG monitors using SEF90% or SEF95% and BIS to differentiate between conscious (Ramsay score 4) and unconscious sedation (Ramsay score ...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/s001340000761

    authors： Walder B,Suter PM,Romand JA

    更新日期：2001-01-01 00:00:00

  • The effect of iNOS deletion on hepatic gluconeogenesis in hyperdynamic murine septic shock.

    abstract：OBJECTIVE:To investigate the role of the inducible nitric oxide synthase activation-induced excess nitric oxide formation on the rate of hepatic glucose production during fully resuscitated murine septic shock. DESIGN:Prospective, controlled, randomized animal study. SETTING:University animal research laboratory. SU...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-007-0638-7

    authors： Albuszies G,Vogt J,Wachter U,Thiemermann C,Leverve XM,Weber S,Georgieff M,Radermacher P,Barth E

    更新日期：2007-06-01 00:00:00

  • The effect of sepsis and its inflammatory response on mechanical clot characteristics: a prospective observational study.

    abstract：PURPOSE:Sepsis and its progression are known to have a major influence on the coagulation system. Current coagulation tests are of limited use when assessing coagulation in sepsis patients. This study aims to assess the potential for a new functional biomarker of clot microstructure, fractal dimension, to identify chan...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-016-4496-z

    authors： Davies GR,Pillai S,Lawrence M,Mills GM,Aubrey R,D'Silva L,Battle C,Williams R,Brown R,Thomas D,Morris K,Evans PA

    更新日期：2016-12-01 00:00:00

  • The impact of perioperative atelectasis on antibiotic penetration into lung tissue: an in vivo microdialysis study.

    abstract：OBJECTIVE:Postoperative pneumonia is a potentially devastating complication associated with high mortality in intensive care unit (ICU)-patients. One of the major predisposing factors is the perioperative occurrence of atelectatic formations in non-dependent lung areas. Perioperative ventilation/perfusion mismatch due ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-008-1122-8

    authors： Hutschala D,Kinstner C,Skhirtladze K,Mayer-Helm BX,Zeitlinger M,Wisser W,Müller M,Tschernko E

    更新日期：2008-10-01 00:00:00

  • The ICM research agenda on critical care ultrasonography.

    abstract：PURPOSE:Critical care ultrasonography has utility for the diagnosis and management of critical illness and is in widespread use by frontline intensivists. As there is a need for research to validate and extend its utility, the Editor of Intensive Care Medicine included critical care ultrasonography as a topic in the IC...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/s00134-017-4734-z

    authors： Mayo P,Arntfield R,Balik M,Kory P,Mathis G,Schmidt G,Slama M,Volpicelli G,Xirouchaki N,McLean A,Vieillard-Baron A

    更新日期：2017-09-01 00:00:00

  • Bedside colonoscopy for critically ill patients with acute lower gastrointestinal bleeding.

    abstract：OBJECTIVE:To determine the clinical impact of bedside colonoscopy for critically ill patients with acute lower gastrointestinal (GI) bleeding. DESIGN AND SETTING:A 3-year retrospective analysis (chart review). Medical intensive care unit (ICU) of a 1,312-bed tertiary-care center in Taiwan. PATIENTS AND PARTICIPANTS:F...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-005-2604-6

    authors： Lin CC,Lee YC,Lee H,Lin JT,Ho WC,Chen TH,Wang HP

    更新日期：2005-05-01 00:00:00

  • Plasma levels of the three endothelial-specific proteins von Willebrand factor, tissue factor pathway inhibitor, and thrombomodulin do not predict the development of acute respiratory distress syndrome.

    abstract：OBJECTIVE:To determine if the plasma levels of three endothelial-specific proteins, von Willebrand factor (vWF), tissue factor pathway inhibitor (TFPI) and thrombomodulin (TM) may be useful in predicting the development of acute respiratory distress syndrome (ARDS). DESIGN:Blood samples were obtained from normal healt...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340051054

    authors： Bajaj MS,Tricomi SM

    更新日期：1999-11-01 00:00:00

  • Genetic variants in the angiopoietin-2 gene are associated with increased risk of ARDS.

    abstract：OBJECTIVE:Angiopoietin-2 (Ang-2) is a potent regulator of vascular permeability and inflammation in acute lung injury and acute respiratory distress syndrome (ARDS). Genetic variants in the Ang-2 gene may lead to altered activities of Ang-2 (or ANGPT2) gene. The aim of this study was to assess if genetic variants of An...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-009-1413-8

    authors： Su L,Zhai R,Sheu CC,Gallagher DC,Gong MN,Tejera P,Thompson BT,Christiani DC

    更新日期：2009-06-01 00:00:00

  • Association between urokinase haplotypes and outcome from infection-associated acute lung injury.

    abstract：OBJECTIVE:Alterations in coagulation, including elevated pulmonary and systemic concentrations of urokinase, are frequent in patients with acute lung injury (ALI). Urokinase potentiates neutrophil activation and contributes to the severity of pulmonary injury in preclinical models of ALI. The objective of this study wa...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00134-007-0930-6

    authors： Arcaroli J,Sankoff J,Liu N,Allison DB,Maloney J,Abraham E

    更新日期：2008-02-01 00:00:00

  • Slow moderate pressure recruitment maneuver minimizes negative circulatory and lung mechanic side effects: evaluation of recruitment maneuvers using electric impedance tomography.

    abstract：OBJECTIVE:To evaluate the efficacy of different lung recruitment maneuvers using electric impedance tomography. DESIGN AND SETTING:Experimental study in animal model of acute lung injury in an animal research laboratory. SUBJECTS:Fourteen pigs with saline lavage induced lung injury. INTERVENTIONS:Lung volume, region...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-005-2799-6

    authors： Odenstedt H,Lindgren S,Olegård C,Erlandsson K,Lethvall S,Aneman A,Stenqvist O,Lundin S

    更新日期：2005-12-01 00:00:00

  • Effects of rapid permissive hypercapnia on hemodynamics, gas exchange, and oxygen transport and consumption during mechanical ventilation for the acute respiratory distress syndrome.

    abstract：OBJECTIVE:To measure the effects of rapid permissive hypercapnia on hemodynamics and gas exchange in patients with acute respiratory distress syndrome (ARDS). DESIGN:Prospective study. SETTING:18-bed, medical intensive care unit, university hospital. PATIENTS:11 mechanically ventilated ARDS patients. INTERVENTION:P...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章

    doi：10.1007/BF01712235

    authors： Thorens JB,Jolliet P,Ritz M,Chevrolet JC

    更新日期：1996-03-01 00:00:00

  • Evaluation of the catheter positioning for neurally adjusted ventilatory assist.

    abstract：PURPOSE:During neurally adjusted ventilatory assist (NAVA) the ventilator is driven by the patients electrical activation of the diaphragm (EAdi), detected by a special esophageal catheter. A reliable positioning of the EAdi-catheter is mandatory to trace a representative EAdi signal. We aimed to determine whether a fo...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-009-1587-0

    authors： Barwing J,Ambold M,Linden N,Quintel M,Moerer O

    更新日期：2009-10-01 00:00:00

  • Will your patient benefit from palliative care? A multicenter exploratory survey about the acceptance of trigger factors for palliative care consultations among ICU physicians.

    abstract：: ...

    journal_title：Intensive care medicine

    pub_type： 评论,信件

    doi：10.1007/s00134-018-5461-9

    authors： Adler K,Schlieper D,Kindgen-Milles D,Meier S,Schallenburger M,Sellmann T,Schwager H,Schwartz J,Neukirchen M

    更新日期：2019-01-01 00:00:00

  • Effect of changes over time in the performance of a customized SAPS-II model on the quality of care assessment.

    abstract：PURPOSE:The aim of our study was to explore, using an innovative method, the effect of temporal changes in the mortality prediction performance of an existing model on the quality of care assessment. The prognostic model (rSAPS-II) was a recalibrated Simplified Acute Physiology Score-II model developed for very elderly...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-011-2390-2

    authors： Minne L,Eslami S,de Keizer N,de Jonge E,de Rooij SE,Abu-Hanna A

    更新日期：2012-01-01 00:00:00

  • Association of PEEP with two different inflation volumes in ARDS patients: effects on passive lung deflation and alveolar recruitment.

    abstract：OBJECTIVE:To assess the effects of the association of positive end-expiratory pressure (PEEP) with different inflation volumes (V(T)'s) on passive lung deflation and alveolar recruitment in ARDS patients. DESIGN:Clinical study using PEEP with two different V(T)'s and analyzing whether passive lung deflation and alveol...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340051275

    authors： Chelucci GL,Dall'Ava-Santucci J,Dhainaut JF,Chelucci A,Allegra A,Lockhart A,Zin WA,Milic-Emili J

    更新日期：2000-07-01 00:00:00

  • Inferior vena cava collapsibility to guide fluid removal in slow continuous ultrafiltration: a pilot study.

    abstract：OBJECTIVE:To investigate whether ultrasound determination of the inferior vena cava diameter (IVCD) and its collapsibility index (IVCCI) could be used to optimize the fluid removal rate while avoiding hypotension during slow continuous ultrafiltration (SCUF). METHODS:Twenty-four consecutive patients [13 men and 11 wom...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-009-1745-4

    authors： Guiotto G,Masarone M,Paladino F,Ruggiero E,Scott S,Verde S,Schiraldi F

    更新日期：2010-04-01 00:00:00

  • Acute respiratory distress syndrome mimickers lacking common risk factors of the Berlin definition.

    abstract：PURPOSE:Some patients presenting with acute respiratory failure and meeting the Berlin criteria for acute respiratory distress syndrome (ARDS) lack exposure to common risk factors (CRF). These so-called ARDS mimickers often lack histological diffuse alveolar damage. We aimed to describe such ARDS mimickers lacking CRF ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-015-4064-y

    authors： Gibelin A,Parrot A,Maitre B,Brun-Buisson C,Mekontso Dessap A,Fartoukh M,de Prost N

    更新日期：2016-02-01 00:00:00

  • Effects of nicotinamide, an inhibitor of PARS activity, on gut and liver O2 exchange and energy metabolism during hyperdynamic porcine endotoxemia.

    abstract：OBJECTIVE:To investigate the effects of nicotinamide (NIC), an inhibitor of poly(ADP-ribose) synthetase (PARS), on intestinal and liver perfusion, O2 kinetics, and energy metabolism over 24 h of hyperdynamic porcine endotoxemia. DESIGN:Prospective, randomized, controlled experimental study with repeated measures. SET...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340000842

    authors： Theisen M,Träger K,Tugtekin I,Stehr A,Ploner F,Georgieff M,Radermacher P,Matĕjovic M

    更新日期：2001-03-01 00:00:00

  • Hypertensive crisis immediately after complete removal of phaeochromocytoma.

    abstract：:A hypertensive crisis with an arterial blood pressure of 280/180 mmHg developed immediately after an apparently successful removal of a phaeochromocytoma. The blood pressure could not be lowered by phentolamine and not until the administration of dihydralazine and furosemide was the systemic pressure normalized. In ad...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF00315379

    authors： Johansson H,Brismar B,Hedenstierna G

    更新日期：1986-01-01 00:00:00

  • Adverse cardiac events during catecholamine vasopressor therapy: a prospective observational study.

    abstract：PURPOSE:To determine the incidence of and risk factors for adverse cardiac events during catecholamine vasopressor therapy in surgical intensive care unit patients with cardiovascular failure. METHODS:The occurrence of any of seven predefined adverse cardiac events (prolonged elevated heart rate, tachyarrhythmia, myoc...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2531-2

    authors： Schmittinger CA,Torgersen C,Luckner G,Schröder DC,Lorenz I,Dünser MW

    更新日期：2012-06-01 00:00:00

  • Increased lactate/pyruvate ratio with normal beta-hydroxybutyrate/acetoacetate ratio and lack of oxygen supply dependency in a patient with fatal septic shock.

    abstract：:We report a case of fatal septic shock, with hyperlactatemia and blood cultures positive for Streptococcus pneumoniae, in a 70-year-old patient. On two occasions (5 days, and 2 days before the patient's death), the relationship between oxygen delivery (DO2) and consumption (VO2) was examined in conjunction with two pr...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340050300

    authors： Gallet D,Goudable J,Vedrinne JM,Viale JP,Annat G

    更新日期：1997-01-01 00:00:00

  • Interferon gamma in trauma-related infections.

    abstract：OBJECTIVE:The efficacy of interferon gamma therapy in reducing infection and improving outcome from infection in patients sustaining major injury was examined. DESIGN:Randomized double-blind placebo control trial SETTING:Nine level one university affiliated trauma centers in the United States. PATIENTS AND PARTICIPA...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1007/BF01743725

    authors： Dries DJ

    更新日期：1996-10-01 00:00:00

  • Right ventricular performance in patients with acute respiratory failure.

    abstract：:To examine the right ventricular response to acute respiratory failure, serial studies of biventricular performance were analysed in 34 such patients, specifically detailing the role of associated underlying disease. During the initial study, the 34 patients with acute respiratory failure had a higher right ventricula...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF00256963

    authors： Brunet F,Dhainaut JF,Devaux JY,Huyghebaert MF,Villemant D,Monsallier JF

    更新日期：1988-01-01 00:00:00

  • Influence of inspiration:expiration ratio on intracranial and cerebral perfusion pressure in acute stroke patients.

    abstract：OBJECTIVE:We undertook this study to evaluate the influence of the inspiration:expiration (I:E) ratio on intracranial pressure and cerebral perfusion in patients with acute stroke. DESIGN:Ventilated patients with acute stroke were examined under a protocol involving variations of I:E ratio from 1:2 to 1:1 to 1:2 under...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-002-1351-1

    authors： Georgiadis D,Schwarz S,Kollmar R,Baumgartner RW,Schwab S

    更新日期：2002-08-01 00:00:00

  • Comparison of norepinephrine and dobutamine to epinephrine for hemodynamics, lactate metabolism, and gastric tonometric variables in septic shock: a prospective, randomized study.

    abstract：OBJECTIVES:To compare the effects of norepinephrine and dobutamine to epinephrine on hemodynamics, lactate metabolism, and gastric tonometric variables in hyperdynamic dopamine-resistant septic shock. DESIGN:A prospective, intervention, randomized clinical trial. SETTING:Adult medical/surgical intensive care unit in ...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/s001340050329

    authors： Levy B,Bollaert PE,Charpentier C,Nace L,Audibert G,Bauer P,Nabet P,Larcan A

    更新日期：1997-03-01 00:00:00

  • Neurodevelopmental, educational and behavioral outcome at 8 years after neonatal ECMO: a nationwide multicenter study.

    abstract：PURPOSE:Reporting neurodevelopmental outcome of 8-year-old children treated with neonatal extracorporeal membrane oxygenation (ECMO). METHODS:In a follow-up study in 135 8-year-old children who received neonatal ECMO between 1996 and 2001 we assessed intelligence (Revised Amsterdam Intelligence Test), concentration (B...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00134-013-2973-1

    authors： Madderom MJ,Reuser JJ,Utens EM,van Rosmalen J,Raets M,Govaert P,Steiner K,Gischler SJ,Tibboel D,van Heijst AF,Ijsselstijn H

    更新日期：2013-09-01 00:00:00

  • Effects of pulmonary blood volume on vascular reactivity in the lung.

    abstract：OBJECTIVE:Pulmonary flow resistance is mainly determined by vessel calibres, resulting from the interaction of volume-passive distension and active vasomotion. However, quantitative information on the interplay between these counteracting forces in the lung is lacking. Therefore, we aimed at quantifying (1) the effects...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340051090

    authors： Ding ZP,Scheeren TW,Arndt JO

    更新日期：1999-12-01 00:00:00

  • Differential ventilation in unilateral lung disease: effects on respiratory mechanics and gas exchange.

    abstract：:Conventional PEEP ventilation has been recently reported to be deleterious in some cases of ARF with unilateral pneumonia. In such respect, two cases of unilateral bacterial pneumonia were intubated with a Carlens tracheal tube. Measurement of tidal volume, static compliance, and functional residual capacity of each l...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01683935

    authors： Rivara D,Bourgain JL,Rieuf P,Harf A,Lemaire F

    更新日期：1979-11-01 00:00:00

  • HMGB1 and LPS induce distinct patterns of gene expression and activation in neutrophils from patients with sepsis-induced acute lung injury.

    abstract：OBJECTIVES:Circulating levels of the proinflammatory mediator High Mobility Group Box Protein 1 (HMGB1) are increased in septic patients and may contribute to sepsis-induced organ dysfunction. Although HMGB1 has been shown to activate neutrophils from healthy volunteers, the responses of neutrophils from septic patient...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-007-0748-2

    authors： Silva E,Arcaroli J,He Q,Svetkauskaite D,Coldren C,Nick JA,Poch K,Park JS,Banerjee A,Abraham E

    更新日期：2007-10-01 00:00:00

  • Implications of different fluid overload definitions in pediatric stem cell transplant patients requiring continuous renal replacement therapy.

    abstract：PURPOSE:In critically ill pediatric patients, fluid overload (FO) >10% has been identified as a threshold for possible interventions, including initiation of continuous renal replacement therapy (CRRT). However, multiple definitions have been reported, and there remains no consensus method for FO calculation. The goal ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2503-6

    authors： Lombel RM,Kommareddi M,Mottes T,Selewski DT,Han YY,Gipson DS,Collins KL,Heung M

    更新日期：2012-04-01 00:00:00