当前位置： SCI文献检索 > INTENSIVE CARE MEDICINE期刊下所有文献 > Pressure-volume curves with and without muscle paralysis in acute respiratory distress syndrome.

Pressure-volume curves with and without muscle paralysis in acute respiratory distress syndrome.

Abstract：

OBJECTIVE:Pressure-volume (PV) curves are recorded after induction of complete muscle paralysis, which may limit their clinical use. The feasibility of recording PV curves without paralysis has not been tested. In 19 patients with acute respiratory distress syndrome (ARDS) and no hemodynamic instability we prospectively evaluated whether PV curves can be safely and reliably recorded under deep sedation without neuromuscular blockade. METHODS:After standardized sedation (continuous infusion of midazolam and fentanyl) PV curves were recorded during apneic sedation, defined as absence of respiratory effort during a 6-s expiratory pause and during paralysis induced by cis-atracurium. MEASUREMENTS AND RESULTS:Agreement between PV curve parameters in the two conditions was evaluated. Curves were obtained from 10 cmH2O and from zero end-expiratory pressure in all patients under apneic sedation. In five patients propofol was given in addition to midazolam and fentanyl, and in two of them fluid resuscitation was needed. A strong agreement was found for respiratory system compliance and the lower inflection point and for chest wall compliance in the five patients whose esophageal pressure was measured. The variability of the measurements, however, should be taken into account in clinical practice. CONCLUSION:Neuromuscular blockade can be dispensed with when recording PV curves in many ARDS patients. Reliable PV curves can be obtained under anesthesia alone, with no serious adverse effects.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Decailliot F,Demoule A,Maggiore SM,Jonson B,Duvaldestin P,Brochard L

doi

10.1007/s00134-006-0265-8

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

1322-8

issue

9

eissn

0342-4642

issn

1432-1238

journal_volume

32

pub_type

杂志文章,随机对照试验

相关文献

INTENSIVE CARE MEDICINE文献大全
  • Time to intra-arrest therapeutic hypothermia in out-of-hospital cardiac arrest patients and its association with neurologic outcome: a propensity matched sub-analysis of the PRINCESS trial.

    abstract：PURPOSE:To study the association between early initiation of intra-arrest therapeutic hypothermia and neurologic outcome in out-of-hospital cardiac arrest. METHODS:A prespecified sub-analysis of the PRINCESS trial (NCT01400373) that randomized 677 bystander-witnessed cardiac arrests to transnasal evaporative intra-arr...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-020-06024-3

    authors： Awad A,Taccone FS,Jonsson M,Forsberg S,Hollenberg J,Truhlar A,Ringh M,Abella BS,Becker LB,Vincent JL,Svensson L,Nordberg P

    更新日期：2020-07-01 00:00:00

  • A profile of European ICU nursing.

    abstract：OBJECTIVE:To evaluate major similarities and major differences between Western European countries in intensive care unit (ICU) nurse staffing, education, training, responsibilities, and initiative. DESIGN:A questionnaire was sent to Western European doctor members of the European Society of Intensive Care Medicine, to...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s001340050693

    authors： Depasse B,Pauwels D,Somers Y,Vincent JL

    更新日期：1998-09-01 00:00:00

  • High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study.

    abstract：PURPOSE:Little evidence of increased thrombotic risk is available in COVID-19 patients. Our purpose was to assess thrombotic risk in severe forms of SARS-CoV-2 infection. METHODS:All patients referred to 4 intensive care units (ICUs) from two centers of a French tertiary hospital for acute respiratory distress syndrom...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00134-020-06062-x

    authors： Helms J,Tacquard C,Severac F,Leonard-Lorant I,Ohana M,Delabranche X,Merdji H,Clere-Jehl R,Schenck M,Fagot Gandet F,Fafi-Kremer S,Castelain V,Schneider F,Grunebaum L,Anglés-Cano E,Sattler L,Mertes PM,Meziani F,CRICS TR

    更新日期：2020-06-01 00:00:00

  • Secondary exposure of medical staff to sarin vapor in the emergency room.

    abstract：OBJECTIVE:To clarify the risk of secondary exposure of medical staff to sarin vapor in the emergency room, and to warn emergency room staffs of the hazard. DESIGN:Retrospective observational survey. SETTING:Emergency department of a university hospital in a metropolitan area of Japan. PARTICIPANTS:Fifteen doctors tr...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01700667

    authors： Nozaki H,Hori S,Shinozawa Y,Fujishima S,Takuma K,Sagoh M,Kimura H,Ohki T,Suzuki M,Aikawa N

    更新日期：1995-12-01 00:00:00

  • Intensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care.

    abstract：OBJECTIVE:To investigate the effectiveness of an enhanced software Model Predictive Control (eMPC) algorithm for intravenous insulin infusion, targeted at tight glucose control in critically ill patients, over 72 h, in two intensive care units with different management protocols. DESIGN:Comparison with standard care i...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1007/s00134-008-1236-z

    authors： Cordingley JJ,Vlasselaers D,Dormand NC,Wouters PJ,Squire SD,Chassin LJ,Wilinska ME,Morgan CJ,Hovorka R,Van den Berghe G

    更新日期：2009-01-01 00:00:00

  • Early organ dysfunction course, cooling time and outcome in classic heatstroke.

    abstract：PURPOSE:To describe the course of early organ dysfunction in a cohort of patients admitted in ICU suffering classic heatstroke. METHODS:Prospective observational single-centre cohort study with a 1-year follow-up. INTERVENTIONS:None. MEASUREMENTS AND MAIN RESULTS:Clinical and biological data of 22 patients were anal...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-009-1500-x

    authors： Pease S,Bouadma L,Kermarrec N,Schortgen F,Régnier B,Wolff M

    更新日期：2009-08-01 00:00:00

  • Could resuscitation be based on microcirculation data? We are not sure.

    abstract：: ...

    journal_title：Intensive care medicine

    pub_type： 信件

    doi：10.1007/s00134-018-5180-2

    authors： Monnet X,Saugel B

    更新日期：2018-06-01 00:00:00

  • Increased long-term mortality with plasma transfusion after coronary artery bypass surgery.

    abstract：PURPOSE:Patients undergoing cardiac surgery often require transfusions of red blood cells, plasma and platelets. These components differ widely in both indications for use and composition. However, from a statistical point of view there is a significant colinearity between the components. This study explores the relati...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2723-9

    authors： Bjursten H,Dardashti A,Ederoth P,Brondén B,Algotsson L

    更新日期：2013-03-01 00:00:00

  • Effect of oxygen affinity on systemic perfusion and brain tissue oxygen tension after extreme hemodilution with hemoglobin-starch conjugates in rats.

    abstract：PURPOSE:To determine the oxygen affinity for optimal tissue oxygen delivery with a hemoglobin-hydroxyethyl starch conjugate (HRC 101). METHODS:Anesthetized rats were hemodiluted (180 ml kg(-1)) with low (P(50) approximately 70 mmHg) or high affinity (P(50) approximately 14 mmHg) HRC 101 at hemoglobin (Hb) concentratio...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-009-1532-2

    authors： Hare GM,Liu E,Baker AJ,Mazer CD

    更新日期：2009-11-01 00:00:00

  • Chest compressions versus ventilation plus chest compressions in a pediatric asphyxial cardiac arrest animal model.

    abstract：OBJECTIVE:To compare the ventilation achieved with chest compressions (CC) or ventilation plus compressions (VC) in a pediatric animal model of cardiac arrest. DESIGN:Randomized experimental study. SETTING:Experimental department of a University Hospital. METHODS:Twelve infant pigs with asphyxial cardiac arrest. Seq...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-010-1777-9

    authors： Iglesias JM,López-Herce J,Urbano J,Solana MJ,Mencía S,Del Castillo J

    更新日期：2010-04-01 00:00:00

  • Outcome and prognostic features of intensive care unit treatment in patients with hematological malignancies.

    abstract：OBJECTIVE:To assess the outcome of intensive care unit (ICU) treatment in patients with hematological malignancies. DESIGN AND SETTING:Retrospective cohort study in the medical ICU of a university hospital. PATIENTS:104 critically ill patients after receiving conventional chemotherapy or autologous hematopoietic stem...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-002-1420-5

    authors： Kroschinsky F,Weise M,Illmer T,Haenel M,Bornhaeuser M,Hoeffken G,Ehninger G,Schuler U

    更新日期：2002-09-01 00:00:00

  • Procalcitonin and C-reactive protein plasma concentrations in nonseptic uremic patients undergoing hemodialysis.

    abstract：OBJECTIVE:To assess procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations and clearance in nonseptic end-stage renal failure patients undergoing their first three hemodialysis sessions. DESIGN AND SETTING:Prospective observational consecutive clinical study at a university hospital. PATIENTS:The stud...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-003-1664-8

    authors： Dahaba AA,Rehak PH,List WF

    更新日期：2003-04-01 00:00:00

  • Safety and efficacy of colistin compared with imipenem in the treatment of ventilator-associated pneumonia: a matched case-control study.

    abstract：OBJECTIVE:Our study aimed to determine the efficacy and safety of colistin in the treatment of ventilator-associated pneumonia (VAP) caused by pan-drug-resistant Pseudomonas aeruginosa or Acinetobacter baumanii. DESIGN:Pairwise, retrospective exposed-unexposed study. SETTING:Combined medical and surgical intensive ca...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-007-0675-2

    authors： Kallel H,Hergafi L,Bahloul M,Hakim A,Dammak H,Chelly H,Hamida CB,Chaari A,Rekik N,Bouaziz M

    更新日期：2007-07-01 00:00:00

  • Central venous catheter infections: concepts and controversies.

    abstract：:Central venous catheters (CVCs) are widely used in critically ill patients in intensive care units. However, infectious complications are common and may limit their utility. We critically review the literature to determine the impact of CVC design and composition, insertion site selection, insertion procedures, care a...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/BF01726542

    authors： Reed CR,Sessler CN,Glauser FL,Phelan BA

    更新日期：1995-02-01 00:00:00

  • Induced hypertension after head injury.

    abstract：:The use of induced hypertension in head injury patients is controversial. We present the case of a 19-year-old man admitted with severe head trauma after a road accident and describe the beneficial effects that increasing arterial blood pressure had on the cerebral perfusion pressure, cerebral blood flow and jugular b...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/s001340050997

    authors： Ferring M,Berré J,Vincent JL

    更新日期：1999-09-01 00:00:00

  • Hydrostatic mechanisms may contribute to the pathogenesis of human re-expansion pulmonary edema.

    abstract：OBJECTIVE:The primary objective was to test the hypothesis that clinical re-expansion pulmonary edema is predominantly due to increased permeability of the alveolar-capillary barrier. A secondary objective was to determine if the alveolar epithelium was functionally intact in patients with re-expansion pulmonary edema ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-004-2379-1

    authors： Sue RD,Matthay MA,Ware LB

    更新日期：2004-10-01 00:00:00

  • Treatment of respiratory failure using minitracheotomy and intratracheal oxygenation in selected patients with chronic lung disease.

    abstract：OBJECTIVE:To evaluate the efficacy of minitracheotomy (MT) insertion for intratracheal oxygen insufflation (ITO2) on arterial blood gases and survival in patients with respiratory failure from chronic lung disease. DESIGN:Open, prospective clinical study. SETTING:A 12-bed medical intensive care unit in a non-universi...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章

    doi：10.1007/BF01709545

    authors： Andrivet P,Richard G,Viau F,Letinier JY,Darne C,Vu Ngoc C

    更新日期：1996-12-01 00:00:00

  • Pain relief with low-dose intravenous clonidine in a child with severe burns.

    abstract：:The case of an 11-year-old boy who suffered second and third degree burns to 78% of his body is reported. The large doses of morphine used as analgesia resulted in severe side effects: ventilatory dependence, impairment of gastrointestinal function and psychological disturbance. Intravenous lignocaine was added withou...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01712245

    authors： Lyons B,Casey W,Doherty P,McHugh M,Moore KP

    更新日期：1996-03-01 00:00:00

  • The diagnostic accuracy of clinical examination for estimating cardiac index in critically ill patients: the Simple Intensive Care Studies-I.

    abstract：PURPOSE:Clinical examination is often the first step to diagnose shock and estimate cardiac index. In the Simple Intensive Care Studies-I, we assessed the association and diagnostic performance of clinical signs for estimation of cardiac index in critically ill patients. METHODS:In this prospective, single-centre coho...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-019-05527-y

    authors： Hiemstra B,Koster G,Wiersema R,Hummel YM,van der Harst P,Snieder H,Eck RJ,Kaufmann T,Scheeren TWL,Perner A,Wetterslev J,de Smet AMGA,Keus F,van der Horst ICC,SICS Study Group.

    更新日期：2019-02-01 00:00:00

  • Right ventricular performance in patients with acute respiratory failure.

    abstract：:To examine the right ventricular response to acute respiratory failure, serial studies of biventricular performance were analysed in 34 such patients, specifically detailing the role of associated underlying disease. During the initial study, the 34 patients with acute respiratory failure had a higher right ventricula...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF00256963

    authors： Brunet F,Dhainaut JF,Devaux JY,Huyghebaert MF,Villemant D,Monsallier JF

    更新日期：1988-01-01 00:00:00

  • Ionized hypocalcemia during out-of-hospital cardiac arrest and cardiopulmonary resuscitation is not due to binding by lactate.

    abstract：OBJECTIVE:To determine the relationship between ionized calcium concentrations and blood lactate levels during cardiac arrest and cardiopulmonary resuscitation (CPR). DESIGN:A prospective cohort study. SETTING:Emergency department (ED) and general intensive care unit in a city hospital (tertiary care center). PATIEN...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340050493

    authors： Gando S,Igarashi M,Kameue T,Nanzaki S

    更新日期：1997-12-01 00:00:00

  • Errors in tracheal pressure recording in patients with a tracheostomy tube--a model study.

    abstract：:The recording of intratracheal pressure in patients breathing through a tracheostomy tube is marred by methodological problems. In model experiments it has been shown that the introduction of a recording catheter into the tracheostomy tube alters the recorded pressure by as much as 20-40%. To avoid such inaccuracy, a ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01735176

    authors： Holst M,Striem J,Hedenstierna G

    更新日期：1990-01-01 00:00:00

  • Plasma exchange in rhabdomyolysis.

    abstract：:The effect of plasma exchange (PE) was evaluated in 4 patients with rhabdomyolysis. A single 21 PE produced a transient fall of creatinine phosphokinase and did not prevent renal failure. Theoretically PE would need to be performed very frequently to remove toxins in appropriate amounts. Since renal failure in myoglob...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF00273565

    authors： Cornelissen JJ,Haanstra W,Haarman HJ,Derksen RH

    更新日期：1989-01-01 00:00:00

  • Inhalation of NO during myocardial ischemia reduces infarct size and improves cardiac function.

    abstract：PURPOSE:Bioactive NO carriers in circulating blood formed during NO inhalation selectively distribute blood flow to areas in need, and may thus improve collateral perfusion to the area-at-risk in acute myocardial infarction (AMI). Here, we tested the hypothesis that NO inhalation during the ischemic phase of AMI may im...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2605-1

    authors： Neye N,Enigk F,Shiva S,Habazettl H,Plesnila N,Kuppe H,Gladwin MT,Kuebler WM

    更新日期：2012-08-01 00:00:00

  • Focus on randomised clinical trials.

    abstract：: ...

    journal_title：Intensive care medicine

    pub_type： 社论

    doi：10.1007/s00134-018-5468-2

    authors： Perner A,Hjortrup PB,Pettilä V

    更新日期：2018-12-01 00:00:00

  • The relationship between oxygen demand, oxygen uptake, and oxygen supply.

    abstract：:Results of the relationships between oxygen supply, demand, and uptake can be used to interpret cardiac output values, identify types of acute circulatory failure, guide attempts to improve cellular function, and thus prevent the development of multiple organ failure and death. Five steps in the interpretation of card...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/BF01785244

    authors： Vincent JL

    更新日期：1990-01-01 00:00:00

  • The combination of the load/force balance and the frequency/tidal volume can predict weaning outcome.

    abstract：OBJECTIVE:To examine whether an appropriately designed combination of an index of ventilatory endurance and the frequency divided by tidal volume ratio (f/VT) provides prognostic information for weaning outcome not offered by any index alone. DESIGN AND SETTING:Prospective study in a multidisciplinary intensive care u...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-006-0104-y

    authors： Vassilakopoulos T,Routsi C,Sotiropoulou C,Bitsakou C,Stanopoulos I,Roussos C,Zakynthinos S

    更新日期：2006-05-01 00:00:00

  • Physiotherapy does not prevent, or hasten recovery from, ventilator-associated pneumonia in patients with acquired brain injury.

    abstract：OBJECTIVE:To investigate the effect of respiratory physiotherapy on the prevention and treatment of ventilator-associated pneumonia (VAP) for adults in an intensive care unit (ICU) with an acquired brain injury (ABI). DESIGN AND SETTING:Two-part, prospective, randomised controlled trial. PATIENTS:A total of 144 subje...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s00134-008-1278-2

    authors： Patman S,Jenkins S,Stiller K

    更新日期：2009-02-01 00:00:00

  • Luxatio cordis due to right pericardium tear, a difficult diagnosis: report of a case.

    abstract：BACKGROUND:Dislocation of the heart is a rare complication of thoracic blunt trauma. A high index of suspicion of pericardium rupture is necessary to formulate an early diagnosis to reduce morbidity and mortality. PATIENTS:A 23-year-old man suffered a blunt thoracoabdominal trauma and was admitted 3 days later to a un...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-002-1328-0

    authors： Piazza O,De Robertis E,Fraioli G,Tufano R

    更新日期：2002-07-01 00:00:00

  • Ethical assessment of pediatric research protocols.

    abstract：:Specific regulations regarding oversight of research in children vary from country to country, but most share common principles derived from major consensus documents. Whereas the permissibility of research on adults depends heavily upon the informed consent of the subject, the regulation of research in pediatrics is ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-007-0917-3

    authors： Truog RD

    更新日期：2008-01-01 00:00:00