Focus on randomised clinical trials.

abstract：PURPOSE:Reporting neurodevelopmental outcome of 8-year-old children treated with neonatal extracorporeal membrane oxygenation (ECMO). METHODS:In a follow-up study in 135 8-year-old children who received neonatal ECMO between 1996 and 2001 we assessed intelligence (Revised Amsterdam Intelligence Test), concentration (B...

journal_title：Intensive care medicine

authors： Madderom MJ,Reuser JJ,Utens EM,van Rosmalen J,Raets M,Govaert P,Steiner K,Gischler SJ,Tibboel D,van Heijst AF,Ijsselstijn H

更新日期：2013-09-01 00:00:00

abstract：:We present a patient with evidence of severe intravascular hemolysis after mitral valve repair, an established method for the surgical treatment of mitral valve disease to avoid prosthesis related complications. The coincidence of this uncommon complication with hemodynamic instability due to pre-existing myocardial d...

journal_title：Intensive care medicine

authors： Seyr M,Hasibeder W,Furtwaegler W,Antretter H,Mutz NJ

更新日期：1993-01-01 00:00:00

abstract：:In 16 patients with multiple injuries the effect of parenteral administration of a fat emulsion on the pulmonary vascular system has been studied. Using the Hewlett Packard 5600 A Intensive Care System, which allows vital parameters to be sampled at a rate of two values per min, pulmonary artery pressure (PAP) was mon...

journal_title：Intensive care medicine

authors： van Deyk K,Hempel V,Münch F,Kopp M,Graf H,Epple E

更新日期：1983-01-01 00:00:00

abstract：PURPOSE:To assess the impact of lung ultrasound (LU) on clinical decision making in mechanically ventilated critically ill patients. METHODS:One hundred and eighty-nine patients took part in this prospective study. The patients were enrolled in the study when LU was requested by the primary physician for (1) unexplain...

journal_title：Intensive care medicine

authors： Xirouchaki N,Kondili E,Prinianakis G,Malliotakis P,Georgopoulos D

更新日期：2014-01-01 00:00:00

abstract：:This narrative review focuses on thoracic ultrasonography (lung and pleural) with the aim of outlining its utility for the critical care clinician. The article summarizes the applications of thoracic ultrasonography for the evaluation and management of pneumothorax, pleural effusion, acute dyspnea, pulmonary edema, pu...

journal_title：Intensive care medicine

authors： Mayo PH,Copetti R,Feller-Kopman D,Mathis G,Maury E,Mongodi S,Mojoli F,Volpicelli G,Zanobetti M

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To examine the attitudes of the general public regarding who should decide about the withdrawal of life support and to compare these attitudes with those of intensive care personnel. DESIGN:Nationwide postal questionnaire survey. SETTING:Sweden. PARTICIPANTS:One thousand one hundred ninety-six randomly sel...

journal_title：Intensive care medicine

authors： Sjökvist P,Nilstun T,Svantesson M,Berggren L

更新日期：1999-09-01 00:00:00

abstract：PURPOSE:Venous thromboembolism (VTE) is a common but often overlooked life-threatening complication of critical illness. The aim of this cross-sectional survey was to assess current practice of thromboprophylaxis as well as adherence to international guidelines. METHODS:After ethics committee approval, all intensive c...

journal_title：Intensive care medicine

authors： Schaden E,Metnitz PG,Pfanner G,Heil S,Pernerstorfer T,Perger P,Schoechl H,Fries D,Guetl M,Kozek-Langenecker S

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To determine the steady-state plasma and epithelial lining fluid (ELF) concentrations of ceftazidime administered in continuous infusion to critically ill patients with severe nosocomial pneumonia. DESIGN:Prospective, open-label study. SETTING:An intensive care unit and research ward in a university hospita...

journal_title：Intensive care medicine

authors： Boselli E,Breilh D,Rimmelé T,Poupelin JC,Saux MC,Chassard D,Allaouchiche B

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVES:To establish priorities for research in critical care medicine in the UK using survey and nominal group (NG) techniques. DESIGN:The senior doctor and nurse from 325 intensive care units (ICUs) in the UK were invited to contribute up to ten research questions relevant to intensive care organisation, practice...

journal_title：Intensive care medicine

authors： Goldfrad C,Vella K,Bion JF,Rowan KM,Black NA

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:Candidemia is increasingly encountered in critically ill patients with a high fatality rate. The available data in the critically ill suggest that patients with prior surgery are at a higher risk than others. However, little is known about candidemia in medical settings. The main goal of this study was to com...

journal_title：Intensive care medicine

authors： Charles PE,Doise JM,Quenot JP,Aube H,Dalle F,Chavanet P,Milesi N,Aho LS,Portier H,Blettery B

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To clarify the effects of hypercapnia (increased PaCO2) on gastric mucosal oxygenation during anaesthesia in dogs. DESIGN:Prospective, controlled animal study. SETTING:Experimental research laboratory of an university hospital. SUBJECTS:Six chronically instrumented dogs. INTERVENTIONS:Dogs were anaestheti...

journal_title：Intensive care medicine

authors： Schwartges I,Schwarte LA,Fournell A,Scheeren TW,Picker O

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:A closed suction system (CS) maintains connection with the mechanical ventilator during tracheal suctioning and is claimed to limit loss in lung volume and oxygenation. We compared changes in lung volume, oxygenation, airway pressure and hemodynamics during endotracheal suctioning performed with CS and with a...

journal_title：Intensive care medicine

authors： Cereda M,Villa F,Colombo E,Greco G,Nacoti M,Pesenti A

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:To evaluate various treatment strategies in critically ill patients with ischaemic acute renal failure, there is a need for reliable bedside measurements of total renal blood flow (RBF), glomerular filtration rate (GFR) and renal oxygen consumption without the need for urine collection. DESIGN:The continuous...

journal_title：Intensive care medicine

authors： Swärd K,Valsson F,Sellgren J,Ricksten SE

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:It remains uncertain why immunocompetent patients with bacterial community-acquired pneumonia (CAP) die, in spite of adequate antibiotics. METHODS:This is a secondary analysis of the CAPUCI database which was a prospective observational multicentre study. Two hundred and twelve immunocompetent patients admi...

journal_title：Intensive care medicine

authors： Rodriguez A,Lisboa T,Blot S,Martin-Loeches I,Solé-Violan J,De Mendoza D,Rello J,Community-Acquired Pneumonia Intensive Care Units (CAPUCI) Study Investigators.

更新日期：2009-03-01 00:00:00

abstract：:The aim of this investigation was to evaluate the role of ultrasonography in avoiding cranial misplacement of the tracheostomy tube and tracheal ring fractures during percutaneous dilatational tracheostomy (PDT). The tracheas of 26 consecutive ICU patients who had undergone PDT but who later died were removed en bloc ...

journal_title：Intensive care medicine

authors： Sustić A,Kovac D,Zgaljardić Z,Zupan Z,Krstulović B

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:Fibroproliferation markers like procollagen I predict mortality in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). We sought to determine whether bronchoalveolar lavage fluid (BALF) from patients with lung injury contained mediators that would activate procollagen I promo...

journal_title：Intensive care medicine

authors： Budinger GR,Chandel NS,Donnelly HK,Eisenbart J,Oberoi M,Jain M

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the effect of lung volume changes on end-expiratory lung impedance change (ELIC) in mechanically ventilated patients, since we hypothesized that ELIC may be a suitable parameter to monitor lung volume change at the bedside. DESIGN:Clinical trial on patients requiring m...

journal_title：Intensive care medicine

authors： Hinz J,Hahn G,Neumann P,Sydow M,Mohrenweiser P,Hellige G,Burchardi H

更新日期：2003-01-01 00:00:00

abstract：:The effect of enteral feeding on O2-consumption (VO2) and CO2-production (VCO2) was studied in 9 ventilator-dependent patients, who were in a stable condition without signs of hypermetabolism. Resting energy expenditure (REE) in postabsorptive state was assessed and enteral feeding was started by continuous drip (480 ...

journal_title：Intensive care medicine

authors： van den Berg B,Stam H

更新日期：1988-01-01 00:00:00

abstract：:Achievement of a mean blood pressure (MBP) target is one of the hemodynamic goals to ensure an adequate blood perfusion pressure in critically ill patients. Arterial catheter allows for a continuous and precise monitoring of arterial pressure signal. In addition to giving a precise MBP monitoring, analysis of the bloo...

journal_title：Intensive care medicine

authors： Augusto JF,Teboul JL,Radermacher P,Asfar P

更新日期：2011-03-01 00:00:00

abstract：:Paediatric admissions to a general ITU are briefly reviewed. Although it may not be an ideal arrangement it is suggested that children can be safely cared for in such a unit. The problems created by the child with acute upper airway obstruction are discussed to demonstrate the way in which the unit is organized to rec...

journal_title：Intensive care medicine

authors： Eastham EJ,Papadatos J,Cook S,Stoddart JC

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To compare the ventilation achieved with chest compressions (CC) or ventilation plus compressions (VC) in a pediatric animal model of cardiac arrest. DESIGN:Randomized experimental study. SETTING:Experimental department of a University Hospital. METHODS:Twelve infant pigs with asphyxial cardiac arrest. Seq...

journal_title：Intensive care medicine

authors： Iglesias JM,López-Herce J,Urbano J,Solana MJ,Mencía S,Del Castillo J

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To determine the reliability of estimating arterial CO(2) pressure (PaCO(2)) using a recently introduced transcutaneous CO(2) pressure (PtcCO(2)) monitor in severe obese patients. DESIGN:Observational and interventional study. SETTING:District hospital with respiratory ward and bariatric surgery unit. PATI...

journal_title：Intensive care medicine

authors： Maniscalco M,Zedda A,Faraone S,Carratù P,Sofia M

更新日期：2008-07-01 00:00:00

abstract：INTRODUCTION:Most anxiolytics and sedative regimens in the intensive care unit (ICU) impair intellectual function, reducing patient autonomy, and often add to patient morbidity. Using an ICU-validated cognitive assessment tool Adapted Cognitive Exam (ACE), we performed a comparison between dexmedetomidine (DEX) and pro...

journal_title：Intensive care medicine

authors： Mirski MA,Lewin JJ 3rd,Ledroux S,Thompson C,Murakami P,Zink EK,Griswold M

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:Controversy over the optimal intravenous fluid for volume resuscitation continues unabated. Our objectives were to characterize the demographics of physicians who prescribe intravenous colloids and determine factors that enter into their decision to choose a colloid. DESIGN:Questionnaire with 61 items. PAR...

journal_title：Intensive care medicine

authors： Miletin MS,Stewart TE,Norton PG

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:In critical illness, serum total cortisol (TC) may not adequately reflect adrenal function because of reduced cortisol-binding globulin (CBG). AIM:To evaluate adrenal function of critically ill children, using free cortisol index (FCI), calculated free cortisol (cFC), and TC levels. METHODS:Thirty-two crit...

journal_title：Intensive care medicine

authors： Poomthavorn P,Lertbunrian R,Preutthipan A,Sriphrapradang A,Khlairit P,Mahachoklertwattana P

更新日期：2009-07-01 00:00:00

abstract：:We analysed the case histories of 22 patients with life threatening asthma retrospectively. Fifteen patients needed mechanical ventilation. Three patients, all of them in cardiac arrest before or at the moment of admission, died. In five patients, halothane therapy was successfully used as a last resort. No major comp...

journal_title：Intensive care medicine

authors： Rosseel P,Lauwers LF,Baute L

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:Critical care ultrasonography has utility for the diagnosis and management of critical illness and is in widespread use by frontline intensivists. As there is a need for research to validate and extend its utility, the Editor of Intensive Care Medicine included critical care ultrasonography as a topic in the IC...

journal_title：Intensive care medicine

authors： Mayo P,Arntfield R,Balik M,Kory P,Mathis G,Schmidt G,Slama M,Volpicelli G,Xirouchaki N,McLean A,Vieillard-Baron A

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:The evaluation of incidences and relating factors of severe persisting critical illness polyneuropathy (CIP) in survivors of multiple organ failure (MOF). DESIGN:Prospective study with an entry period of 24 months. Electrophysiological studies for the diagnosis of CIP were performed 1 or 2 days before the pa...

journal_title：Intensive care medicine

authors： Mohr M,Englisch L,Roth A,Burchardi H,Zielmann S

更新日期：1997-11-01 00:00:00

abstract：PURPOSE:Although low doses of oxygen (FiO2 <0.50) are considered nontoxic, recent studies have shown that even lower doses increase pulmonary inflammatory mediators. We aimed to evaluate the acute effects of reducing FiO2 on pulmonary inflammation in mechanically ventilated patients without respiratory failure. METHOD...

journal_title：Intensive care medicine

authors： Fernandez R,Gili G,Villagra A,Lopez-Aguilar J,Artigas A

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Because non-invasive mechanical ventilation (NIV) is increasingly used, new devices, both ventilators and interfaces, have been continuously proposed for clinical use in recent years. To provide the clinicians with valuable information about ventilators and interfaces for NIV, several bench studies evaluating a...

journal_title：Intensive care medicine

authors： Olivieri C,Costa R,Conti G,Navalesi P

更新日期：2012-01-01 00:00:00