The endothelium: physiological functions and role in microcirculatory failure during severe sepsis.

abstract：:Knowledge translation is an important step for translational research. In this issue of Intensive Care Medicine, a new mini-series of basic research-related reviews is published. Three invited reviews focus on the role of extracellular matrix in ventilator-induced lung injury and mechanotransduction. The major challen...

journal_title：Intensive care medicine

authors： Liu M

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To assess the effects of the cyclooxygenase inhibitor diclofenac in a canine model of pulmonary occlusion and reperfusion of the left lower lobe (LLL). DESIGN:Twelve adult beagle dogs (13-17 kg) were randomly assigned to a control group (n = 6) and a diclofenac-treated group (n = 6). Animals in the treatment...

journal_title：Intensive care medicine

authors： Segiet W,Krieter H,Stieber C,Albrecht DM,van Ackern K

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:Intracerebral hemorrhage (ICH) is associated with a high mortality. The present study sought to determine the incidence of spontaneous ICH in an intensive care unit (ICU) and associated factors. DESIGN:A 6 year retrospective study. SETTING:A general ICU in a university hospital. PATIENTS:All ICU patients d...

journal_title：Intensive care medicine

authors： Oppenheim-Eden A,Glantz L,Eidelman LA,Sprung CL

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To assess the effects of intravenous fish oil fat emulsion on the metabolic alterations induced by lipopolysaccharide (LPS) challenge in healthy volunteers. DESIGN:Two groups of eight healthy subjects were randomized to receive either two pharmacological doses of intravenous FO fat emulsion or no treatment. ...

journal_title：Intensive care medicine

authors： Pluess TT,Hayoz D,Berger MM,Tappy L,Revelly JP,Michaeli B,Carpentier YA,Chioléro RL

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To determine the adequate site of activated coagulation time (ACT) measurement during continuous haemodiafiltration (CHDF) using nafamostat mesilate. DESIGN:Prospective, consecutive, clinical study. SETTING:An intensive care unit of a general hospital. PATIENTS:Ten patients with acute organ failure includi...

journal_title：Intensive care medicine

authors： Hu ZJ,Iwama H,Suzuki R,Kobayashi S,Akutsu I

更新日期：1999-05-01 00:00:00

abstract：PURPOSE:To compare characteristics, clinical evolution and outcome in adult patients with influenza A (H1N1) acute respiratory distress syndrome (ARDS) treated with or without extracorporeal membrane oxygenation (ECMO). METHODS:A prospective observational study of patients treated in Marseille South Hospital from Octo...

journal_title：Intensive care medicine

authors： Roch A,Lepaul-Ercole R,Grisoli D,Bessereau J,Brissy O,Castanier M,Dizier S,Forel JM,Guervilly C,Gariboldi V,Collart F,Michelet P,Perrin G,Charrel R,Papazian L

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To determine: (1) the proportion of small (<5 mm) or thrombosed internal jugular veins (IJV) and femoral veins (FV) in which catheter placement would be difficult without ultrasound guidance; (2) which position increases central vein sizes and may facilitate cannulation of these vessels. DESIGN:Prospective s...

journal_title：Intensive care medicine

authors： Samy Modeliar S,Sevestre MA,de Cagny B,Slama M

更新日期：2008-02-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Perner A,Hjortrup PB,Pettilä V

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of basic life support, time to first defibrillation and emergency medical service arrival time on neurologic outcome and expenses for hospital care in patients after cardiac arrest. SETTING:Large urban emergency medical services system and emergency department in a 2000-bed university...

journal_title：Intensive care medicine

authors： Bur A,Kittler H,Sterz F,Holzer M,Eisenburger P,Oschatz E,Kofler J,Laggner AN

更新日期：2001-09-01 00:00:00

abstract：:A veno-venous to-and-fro bypass method through a single blood access for extracorporeal lung assist with an artificial membrane lung is introduced. A premature newborn with severe respiratory distress was treated with this method. A 12 Fr. single lumen catheter with a spiral-embedded thin-wall, 0.25 mm in wall thickne...

journal_title：Intensive care medicine

authors： Tsuno K,Terasaki H,Tsutsumi R,Sadanaga M,Higashi K,Morioka T

更新日期：1989-01-01 00:00:00

abstract：:Cardiac arrhythmias and circulatory collapse account for the high mortality reported after severe chloroquine poisoning. We have recently observed a 17-year-old man who ingested an 8 g chloroquine overdose. Cardiac arrest occurred within 1 h. Cardiogenic shock was refractory to epinephrine, dopamine and molar sodium l...

journal_title：Intensive care medicine

authors： Hantson P,Ronveau JL,De Coninck B,Horn JL,Mahieu P,Hassoun A

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:Motivated by a new randomized trial (the PEPTIC trial) that raised the issue of an increase in mortality with proton pump inhibitors (PPIs) relative to histamine-2 receptor antagonists (H2RAs), we updated our prior systematic review and network meta-analysis (NMA) addressing the impact of pharmacological gastro...

journal_title：Intensive care medicine

authors： Wang Y,Ge L,Ye Z,Siemieniuk RA,Reintam Blaser A,Wang X,Perner A,Møller MH,Alhazzani W,Cook D,Guyatt GH

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:The concept of weaning-induced cardiac dysfunction emerged 26 years ago with the publication of a clinical study conducted by François Lemaire and collaborators. OBJECTIVES:One objective of this article is to remember the results and the historical context under which our pivotal study was conducted. Anot...

journal_title：Intensive care medicine

authors： Teboul JL

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:Critically ill patients often develop anaemia which can be related to a number of factors. However, the exact causes of anaemia in many patients remain unexplained. We hypothesized that the relationship between erythropoietin (EPO) and haematocrit may be altered in critically ill patients. DESIGN:Serum conc...

journal_title：Intensive care medicine

authors： Rogiers P,Zhang H,Leeman M,Nagler J,Neels H,Mélot C,Vincent JL

更新日期：1997-02-01 00:00:00

abstract：:Specific regulations regarding oversight of research in children vary from country to country, but most share common principles derived from major consensus documents. Whereas the permissibility of research on adults depends heavily upon the informed consent of the subject, the regulation of research in pediatrics is ...

journal_title：Intensive care medicine

authors： Truog RD

更新日期：2008-01-01 00:00:00

abstract：:A study was conducted to evaluate repeated intrathecal injections of baclofen, without artificial ventilation, in the treatment of severe tetanus. Ten patients, 5 men and 5 women, with a mean age of 34 +/- 7 years, were included in the study. The dose of baclofen injected was 1000 micrograms between the ages of 16 and...

journal_title：Intensive care medicine

authors： Saissy JM,Demazière J,Vitris M,Seck M,Marcoux L,Gaye M,Ndiaye M

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the use of antidotal therapy in patients with an elevated digitalis concentration following chronic or acute exposure. DESIGN AND SETTING:Retrospective review of patient records over 2 years in 20 city hospitals in France. PATIENTS:Overall 838 patients with an elevated serum digitalis concentrat...

journal_title：Intensive care medicine

authors： Lapostolle F,Borron SW,Verdier C,Arnaud F,Couvreur J,Mégarbane B,Baud F,Adnet F

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:The early diagnosis of traumatic internal carotid artery dissection (TICAD) is essential for initiating appropriate treatment and improving outcome. We searched for criteria from transcranial Doppler (TCD) measurements on admission that could be associated with subsequent TICAD diagnosis in patients with trauma...

journal_title：Intensive care medicine

authors： Bouzat P,Francony G,Brun J,Lavagne P,Picard J,Broux C,Declety P,Jacquot C,Albaladejo P,Payen JF

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:(1) To describe the pattern of intracranial pressure (ICP) and cerebral perfusion pressure (CPP) in a group of severe head-injured patients, (2) to quantify complications of ICP monitoring, and (3) to describe a management protocol and its results. DESIGN:Prospective observational study. SETTING:General int...

journal_title：Intensive care medicine

authors： Stocchetti N,Rossi S,Buzzi F,Mattioli C,Paparella A,Colombo A

更新日期：1999-04-01 00:00:00

abstract：:During a 3-year period, a clinical diagnosis of invasive candidosis was made in 8 out of 2054 consecutive surgical intensive care unit (ICU) patients. These patients were retrospectively matched with 16 control patients who underwent similar surgical procedures and had a similar clinical course except for negative Can...

journal_title：Intensive care medicine

authors： Lepper PM,Wiedeck H,Geldner G,Essig A,Trautmann M

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:To investigate the sources of hemorrhage and use of endoscopic hemostasis in patients with clinically significant upper gastrointestinal (UGI) hemorrhage after admission to the intensive care unit (ICU). DESIGN AND SETTING:Prospective study, 123 beds of ICU in a 1,629-bed medical center. MEASUREMENTS AND RE...

journal_title：Intensive care medicine

authors： Lee YC,Wang HP,Wu MS,Yang CS,Chang YT,Lin JT

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To derive recommendations for the dosing of commonly used medications in the morbidly obese patient in the ICU. DATA SOURCES:Articles were obtained through computerized searches involving MEDLINE. The bibliographies of retrieved publications and textbooks were reviewed for additional references. STUDY SELEC...

journal_title：Intensive care medicine

authors： Erstad BL

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:Reporting neurodevelopmental outcome of 8-year-old children treated with neonatal extracorporeal membrane oxygenation (ECMO). METHODS:In a follow-up study in 135 8-year-old children who received neonatal ECMO between 1996 and 2001 we assessed intelligence (Revised Amsterdam Intelligence Test), concentration (B...

journal_title：Intensive care medicine

authors： Madderom MJ,Reuser JJ,Utens EM,van Rosmalen J,Raets M,Govaert P,Steiner K,Gischler SJ,Tibboel D,van Heijst AF,Ijsselstijn H

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:Relatives of intensive care unit (ICU) patients suffer emotional distress that impairs their ability to acquire the information they need from the staff. We sought to evaluate whether providing relatives with a list of important questions was associated with better comprehension on day 5. METHODS:Randomized, p...

journal_title：Intensive care medicine

authors： Azoulay E,Forel JM,Vinatier I,Truillet R,Renault A,Valade S,Jaber S,Durand-Gasselin J,Schwebel C,Georges H,Merceron S,Cariou A,Moussa M,Hraiech S,Argaud L,Leone M,Curtis JR,Kentish-Barnes N,Jouve E,Papazian L

更新日期：2018-11-01 00:00:00

abstract：:One hundred and eighteen 20-g radial artery catheters were prospectively evaluated in 109 cardiovascular surgical patients. 0.024% papaverine in saline was used as a continuous flushing solution. Using the Doppler method, obstruction of the radial artery with the catheter in situ was found in 11 (9.8%) patients. Decan...

journal_title：Intensive care medicine

authors： Weiss BM,Gattiker RI

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective study was to evaluate the value of sinus echography results to directly indicate a transnasal puncture in intubated patients with suspicion of nosocomial maxillary sinusitis. DESIGN:prospective clinical investigation. SETTING:medical intensive care unit. PATIENTS:sixty patients ...

journal_title：Intensive care medicine

authors： Vargas F,Bui HN,Boyer A,Bébear CM,Lacher-Fougére S,De-Barbeyrac BM,Salmi LR,Traissac L,Gbikpi-Benissan G,Gruson D,Hilbert G

更新日期：2006-06-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Amrein K,Oudemans-van Straaten HM,Berger MM

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:Evaluation of an open circuit multiple breath nitrogen washout (MBNW) technique for measurement of functional residual capacity (FRC) during partial ventilatory support using corrections for gas viscosity, sampling delay time, and re-inspired nitrogen. DESIGN:Measurements in a lung model with known reference...

journal_title：Intensive care medicine

authors： Zinserling J,Wrigge H,Varelmann D,Hering R,Putensen C

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of different lung recruitment maneuvers using electric impedance tomography. DESIGN AND SETTING:Experimental study in animal model of acute lung injury in an animal research laboratory. SUBJECTS:Fourteen pigs with saline lavage induced lung injury. INTERVENTIONS:Lung volume, region...

journal_title：Intensive care medicine

authors： Odenstedt H,Lindgren S,Olegård C,Erlandsson K,Lethvall S,Aneman A,Stenqvist O,Lundin S

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To compare outcome prediction using the Multiple Organ Dysfunction Score (MODS) and the Sequential Organ Failure Assessment (SOFA), two of the systems most commonly used to evaluate organ dysfunction in the intensive care unit (ICU). DESIGN:Prospective, observational study. SETTING:Thirty-one-bed, universit...

journal_title：Intensive care medicine

authors： Peres Bota D,Melot C,Lopes Ferreira F,Nguyen Ba V,Vincent JL

更新日期：2002-11-01 00:00:00