Abstract:
:Arterial blood ketone body ratio, reflecting hepatic mitochondrial redox state, was measured in 26 brain-dead patients who were hypotensive but hemodynamically stable. All of them had substantially normal hepatic function. In 18 of the patients, blood ketone body ratio was maintained within the normal range in spite of hypotension. This was in marked contrast to the markedly decreased blood ketone body ratio often observed in patients in shock. This phenomenon was especially conspicuous in those who had not received exogenous dopamine infusion. It is suggested that hepatic mitochondrial redox state can probably be maintained despite systemic hypotension in brain-dead patients. Dopamine administration, on the other hand, is suggested to be a contributing factor to the reduction of hepatic mitochondrial redox state in hypotensive brain-dead patients. This study may provide a guideline for effective preservation of hepatic function in the body of brain-dead patients.
journal_name
Intensive Care Medjournal_title
Intensive care medicineauthors
Nakatani T,Ishikawa Y,Kobayashi K,Ozawa Kdoi
10.1007/BF01691432subject
Has Abstractpub_date
1991-01-01 00:00:00pages
103-7issue
2eissn
0342-4642issn
1432-1238journal_volume
17pub_type
杂志文章abstract::The original version of this article unfortunately contained a mistake. ...
journal_title:Intensive care medicine
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journal_title:Intensive care medicine
pub_type: 杂志文章
doi:10.1007/s001340051090
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journal_title:Intensive care medicine
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pub_type: 杂志文章
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journal_title:Intensive care medicine
pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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更新日期:2010-08-01 00:00:00
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journal_title:Intensive care medicine
pub_type: 杂志文章
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更新日期:1994-01-01 00:00:00
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更新日期:1996-11-01 00:00:00
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更新日期:2011-08-01 00:00:00
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journal_title:Intensive care medicine
pub_type: 杂志文章
doi:10.1007/BF01684390
更新日期:1978-04-01 00:00:00
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journal_title:Intensive care medicine
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章,meta分析
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journal_title:Intensive care medicine
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2003-11-01 00:00:00
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journal_title:Intensive care medicine
pub_type: 杂志文章,评审
doi:10.1007/BF01713977
更新日期:1994-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2006-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2009-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-11-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2018-09-01 00:00:00
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更新日期:2012-01-01 00:00:00