Intrapulmonary percussive ventilation in tracheostomized patients: a randomized controlled trial.

abstract：:Central venous catheters (CVCs) are widely used in critically ill patients in intensive care units. However, infectious complications are common and may limit their utility. We critically review the literature to determine the impact of CVC design and composition, insertion site selection, insertion procedures, care a...

journal_title：Intensive care medicine

authors： Reed CR,Sessler CN,Glauser FL,Phelan BA

更新日期：1995-02-01 00:00:00

abstract：:We report a case of fatal septic shock, with hyperlactatemia and blood cultures positive for Streptococcus pneumoniae, in a 70-year-old patient. On two occasions (5 days, and 2 days before the patient's death), the relationship between oxygen delivery (DO2) and consumption (VO2) was examined in conjunction with two pr...

journal_title：Intensive care medicine

authors： Gallet D,Goudable J,Vedrinne JM,Viale JP,Annat G

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:Hypoxia-ischemia (HI), as a major cause of fetal brain damage, has long-lasting neurological implications. Therefore, therapeutic interventions that attenuate the neuropathological outcome of HI while also improving the neurofunctional outcome are of paramount clinical importance. The aim of this study was to i...

journal_title：Intensive care medicine

authors： Fathali N,Lekic T,Zhang JH,Tang J

更新日期：2010-09-01 00:00:00

abstract：:A 17-year-old patient with Shone's disease had to be readmitted to the hospital 3 months after implantation of an artificial aortic valve because of extreme mitral insufficiency with consecutive pulmonary edema and hepatic dysfunction. He had been orally anticoagulated and presented with a high international normalize...

journal_title：Intensive care medicine

authors： Rauch R,Hofbeck M,Ries M,Singer H,Klinge J

更新日期：1999-10-01 00:00:00

abstract：:Administration of C1-esterase inhibitor (C1-INH) attenuates myocardial necrosis and sustains normal cardiac performance after myocardial ischemia and reperfusion in animal experiments. We report on our first experience of C1-INH application as rescue therapy in patients undergoing emergency surgical revascularization ...

journal_title：Intensive care medicine

authors： Bauernschmitt R,Böhrer H,Hagl S

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:The immediate overwhelming release of inflammatory mediators in septic shock is rapidly followed by strong anti-inflammatory responses inducing a state of immunosuppression. The patients who survive the initial hyper-inflammatory step of septic shock but subsequently die may be those who do not recover from i...

journal_title：Intensive care medicine

authors： Monneret G,Lepape A,Voirin N,Bohé J,Venet F,Debard AL,Thizy H,Bienvenu J,Gueyffier F,Vanhems P

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of intravenous sildenafil for immediate postoperative pulmonary hypertension (PH) in pediatric patients undergoing congenital heart surgery. METHODS:A double-blind, multicenter, placebo-controlled, dose-ranging, parallel-group trial was conducted. Patients were randomized to...

journal_title：Intensive care medicine

authors： Fraisse A,Butrous G,Taylor MB,Oakes M,Dilleen M,Wessel DL

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effectiveness of an enhanced software Model Predictive Control (eMPC) algorithm for intravenous insulin infusion, targeted at tight glucose control in critically ill patients, over 72 h, in two intensive care units with different management protocols. DESIGN:Comparison with standard care i...

journal_title：Intensive care medicine

authors： Cordingley JJ,Vlasselaers D,Dormand NC,Wouters PJ,Squire SD,Chassin LJ,Wilinska ME,Morgan CJ,Hovorka R,Van den Berghe G

更新日期：2009-01-01 00:00:00

abstract：:The oxygen cost of breathing (which is the difference in oxygen consumption measured during controlled ventilation and again during spontaneous ventilation) was measured in 30 patients between the ages of 17 and 96 years at the time of commencement of weaning from mechanical ventilation. There was a significant expone...

journal_title：Intensive care medicine

authors： McDonald NJ,Lavelle P,Gallacher WN,Harpin RP

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:Pulmonary endothelial activation caused by high pulmonary capillary pressures may be involved in the pathogenesis of cardiogenic pulmonary edema (CPE). We studied soluble selectins and soluble ICAM-1 as markers of cell activation in the systemic and pulmonary circulation of patients with respiratory failure (...

journal_title：Intensive care medicine

authors： Geppert A,Zorn G,Heinz G,Huber K,Siostrzonek P

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:Optimal respiratory support for interhospital transport of critically ill children is challenging and has been scarcely investigated. High-flow nasal cannula (HFNC) therapy has emerged as a promising support mode in the paediatric intensive care unit (PICU), but no data are available on HFNC used during interho...

journal_title：Intensive care medicine

authors： Schlapbach LJ,Schaefer J,Brady AM,Mayfield S,Schibler A

更新日期：2014-04-01 00:00:00

abstract：:We investigated the levels of auto-PEEP and dynamic hyperinflation during high frequency jet ventilation (HFJV) and controlled mechanical ventilation (CMV) in six patients with chronic obstructive pulmonary disease within the first 36 h of acute exacerbation. The comparative evaluation was performed at similar conditi...

journal_title：Intensive care medicine

authors： Conti G,Bufi M,Rocco M,Calzecchi E,De Blasi RA,Antonelli M,Pelaia P,Gasparetto A

更新日期：1990-01-01 00:00:00

abstract：:Optimal fluid management is one of the main challenges in the care of the critically ill. However, the physiological parameters that are commonly monitored and used to guide fluid management are often inadequate and even misleading. From 1987 to 1989 we published four experimental studies which described a method for ...

journal_title：Intensive care medicine

authors： Perel A,Pizov R,Cotev S

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:Critically ill patients often require CT scans. Adverse events (AE) can occur during intra-hospital transport (IHT). The aim of this prospective study was to determine the diagnostic and therapeutic yield and the safety of CT scans in ICU patients. METHODS:All ICU patients having a CT scan for diagnostic purpo...

journal_title：Intensive care medicine

authors： Aliaga M,Forel JM,De Bourmont S,Jung B,Thomas G,Mahul M,Bisbal M,Nougaret S,Hraiech S,Roch A,Chaumoitre K,Jaber S,Gainnier M,Papazian L

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:In contrast to indocyanine green (ICG) blood clearance, the plasma disappearance rate (PDR) of ICG does not require absolute ICG blood concentrations and today can be assessed transcutaneously. In this study, we analyzed the relation between ICG disappearance rate and ICG blood clearance as parameters of live...

journal_title：Intensive care medicine

authors： Sakka SG,van Hout N

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To assess the effect of partial liquid ventilation with perfluorocarbons on hemodynamics and gas exchange in large pigs with induced acute lung injury (ALI). DESIGN:Randomized, prospective, double-control, experimental study. Experimental intensive care unit of a university. MATERIALS:Eighteen large pigs (5...

journal_title：Intensive care medicine

authors： Houmes RJ,Verbrugge SJ,Hendrik ER,Lachmann B

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis whether PMN-Elastase in bronchoalveolar lavage fluid (BALF) could reflect neutrophil activity in the lower respiratory tract. DESIGN:Prospectively, morphologic findings of acute and chronic inflammation in the transbronchial lung biopsy specimens were compared with the numbers of neutr...

journal_title：Intensive care medicine

authors： Lengas A,Poletti V,Pacifico L,di Domizio C,Patelli M,Spiga L

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:To determine the magnitude and time course of adrenergic effects on metabolism in volunteers and possible implications for the use of sympathomimetics in the critically ill. DESIGN:Descriptive laboratory investigation. SUBJECTS:7 volunteers. INTERVENTION:Primed continuous infusions of stable isotope tracer...

journal_title：Intensive care medicine

authors： Ensinger H,Träger K,Geisser W,Anhäupl T,Ahnefeld FW,Vogt J,Georgieff M

更新日期：1994-01-01 00:00:00

abstract：:We observed a 51-year-old woman who was admitted for severe amitriptyline overdose. Besides major cardiovascular complications, the patient developed severe hyperpyrexia with a central body temperature of more than 43 degrees C for 5 h. The patient died on day 3 from cardiocirculatory collapse and arrhythmias. Hyperth...

journal_title：Intensive care medicine

authors： Hantson P,Benaissa M,Clemessy JL,Baud FJ

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:Measurement of functional residual capacity (FRC) during mechanical ventilation is important to standardise respiratory system compliance and adjust the ventilator settings to optimise lung recruitment. In the present study we compared three methods to measure FRC. DESIGN:The bias flow nitrogen washout techn...

journal_title：Intensive care medicine

authors： Schibler A,Hammer J,Isler R,Buess C,Newth CJ

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To investigate efficacy and safety of enoxaparin for catheter-related arterial thrombosis in infants with congenital heart disease. DESIGN:Prospective observational study. SETTING:Pediatric Intensive Care and Cardiology Unit at the University Children's Hospital of Zurich. PATIENTS:A cohort of 32[Symbol: s...

journal_title：Intensive care medicine

authors： Bontadelli J,Moeller A,Schmugge M,Schraner T,Kretschmar O,Bauersfeld U,Bernet-Buettiker V,Albisetti M

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To present the efficacy and tolerability of a new oral dosage form of the calcium antagonist nitrendipine compared to nifedipine capsules in patients with hypertensive emergency. DESIGN:Multicenter randomized double blind clinical study. SETTING:23 study centres (hospitals) in Germany. PATIENTS:161 patient...

journal_title：Intensive care medicine

authors： Rohr G,Reimnitz P,Blanke P

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:To assess the reproducibility of respiratory dead space measurements in ventilated children. DESIGN:Prospective study. SETTING:University pediatric intensive care unit. PATIENTS:Thirty-two mechanically ventilated children (0.13-15.4 years) who were clinically stable. METHODS:The single-breath CO(2) test ...

journal_title：Intensive care medicine

authors： Riou Y,Leclerc F,Neve V,Dupuy L,Noizet O,Leteurtre S,Sadik A

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:To measure the effect of intense neuromuscular blockade (NMB) on oxygen consumption (VO(2)) in deeply sedated and mechanically ventilated children on the first day after complex congenital cardiac surgery. DESIGN:Prospective clinical interventional study. SETTING:Pediatric intensive care unit of an universi...

journal_title：Intensive care medicine

authors： Lemson J,Driessen JJ,van der Hoeven JG

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:To document the effect of neurocritical care, delivered by specialist staff and based on protocol-driven therapy aimed at intracranial pressure (ICP) and cerebral perfusion pressure (CPP) targets, on outcome in acute head injury. DESIGN:Retrospective record review to compare presentation, therapy and outcom...

journal_title：Intensive care medicine

authors： Patel HC,Menon DK,Tebbs S,Hawker R,Hutchinson PJ,Kirkpatrick PJ

更新日期：2002-05-01 00:00:00

abstract：:To examine the right ventricular response to acute respiratory failure, serial studies of biventricular performance were analysed in 34 such patients, specifically detailing the role of associated underlying disease. During the initial study, the 34 patients with acute respiratory failure had a higher right ventricula...

journal_title：Intensive care medicine

authors： Brunet F,Dhainaut JF,Devaux JY,Huyghebaert MF,Villemant D,Monsallier JF

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:Inhalation of nitric oxide (NO) can improve oxygenation and decrease mean pulmonary artery pressure (MPAP) in patients with the acute respiratory distress syndrome (ARDS). It is not known whether inhaled NO exerts a similar effect in hypoxemic patients with chronic obstructive pulmonary disease (COPD). DESIG...

journal_title：Intensive care medicine

authors： Blanch L,Joseph D,Fernández R,Mas A,Martinez M,Vallés J,Diaz E,Baigorri F,Artigas A

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the usefulness of early transcranial Doppler ultrasound (TCD) goal-directed therapy after severe traumatic brain injury initiated before invasive cerebral monitoring is available. DESIGN:Prospective, observational clinical study. SETTING:Surgical intensive care unit, university hospital. PATIEN...

journal_title：Intensive care medicine

authors： Ract C,Le Moigno S,Bruder N,Vigué B

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Limiting the duration of invasive ventilation is an important goal in caring for critically ill patients. Several clinical trials have shown that compared to traditional care, protocols can reduce the total duration of mechanical ventilation. Computerized or automated weaning has the potential to improve wea...

journal_title：Intensive care medicine

authors： Burns KE,Lellouche F,Lessard MR

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:An International Consensus Conference proposed classifying weaning into simple, difficult, and prolonged weaning. However, the usefulness of this classification in a respiratory intensive care unit (ICU) is unknown. The aims of the study were: (1) to compare the clinical characteristics and outcomes of patients...

journal_title：Intensive care medicine

authors： Sellares J,Ferrer M,Cano E,Loureiro H,Valencia M,Torres A

更新日期：2011-05-01 00:00:00