Inhaled nitric oxide for a severe respiratory syncytial virus infection in an infant with bronchopulmonary dysplasia.

abstract：OBJECTIVES:To investigate at what time the peak level should be determined under conventional thrice daily (t.i.d.) administration of the aminoglycoside netilmicin and to study its serum concentrations under once daily (od) treatment to define the required daily dose and to gain information about convenient drug monito...

journal_title：Intensive care medicine

authors： Konrad F,Wagner R,Neumeister B,Rommel H,Georgieff M

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:Inflammatory markers may have a role in predicting severity of illness of intensive care unit (ICU) patients. The aim of this study is to determine whether low eosinophil count can predict 28-day mortality in medical ICU. METHODS:A prospective study over a 4-month period. To evaluate the prognosis information ...

journal_title：Intensive care medicine

authors： Abidi K,Belayachi J,Derras Y,Khayari ME,Dendane T,Madani N,Khoudri I,Zeggwagh AA,Abouqal R

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:To determine incidence, risk factors and outcome of tracheal ischemic lesions related to intubation. METHODS:Planned post hoc analysis using patients from a previous randomized controlled study. Fiberoptic tracheoscopy was performed during the 24 h following extubation. In patients with >2 ischemic lesions, ul...

journal_title：Intensive care medicine

authors： Touat L,Fournier C,Ramon P,Salleron J,Durocher A,Nseir S

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:A closed suction system (CS) maintains connection with the mechanical ventilator during tracheal suctioning and is claimed to limit loss in lung volume and oxygenation. We compared changes in lung volume, oxygenation, airway pressure and hemodynamics during endotracheal suctioning performed with CS and with a...

journal_title：Intensive care medicine

authors： Cereda M,Villa F,Colombo E,Greco G,Nacoti M,Pesenti A

更新日期：2001-04-01 00:00:00

abstract：PURPOSE:We assessed feasibility and safety of extracorporeal carbon dioxide removal (ECCO2R) to facilitate ultra-protective ventilation (VT 4 mL/kg and PPLAT ≤ 25 cmH2O) in patients with moderate acute respiratory distress syndrome (ARDS). METHODS:Prospective multicenter international phase 2 study. Primary endpoint w...

journal_title：Intensive care medicine

authors： Combes A,Fanelli V,Pham T,Ranieri VM,European Society of Intensive Care Medicine Trials Group and the “Strategy of Ultra-Protective lung ventilation with Extracorporeal CO2 Removal for New-Onset moderate to severe ARDS” (SUPERNOVA) investigators

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To examine the relationship of fluid balance and weaning outcomes. METHODS:We prospectively collected demographic, physiological, daily fluid balance (measured inputs minus outputs), and weaning data from 87 mechanically ventilated patients. PATIENTS:We examined 87 patients, a median age of 66 years, APACHE...

journal_title：Intensive care medicine

authors： Upadya A,Tilluckdharry L,Muralidharan V,Amoateng-Adjepong Y,Manthous CA

更新日期：2005-12-01 00:00:00

abstract：:Status epilepticus is one of the most frequent neurological emergencies in the intensive care unit. Standard treatment includes intravenous barbiturates, benzodiazepines and phenytoin. However, drug coma is sometimes necessary to control refractory status epilepticus. We report such a case, successfully treated by int...

journal_title：Intensive care medicine

authors： Borgeat A,Wilder-Smith OH,Jallon P,Suter PM

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:This study explored differences in end-of-life (EOL) decisions and respect for patient autonomy of religious members versus those only affiliated to that particular religion (affiliated is a member without strong religious feelings). METHODS:In 2005 structured questionnaires regarding EOL decisions were distri...

journal_title：Intensive care medicine

authors： Bülow HH,Sprung CL,Baras M,Carmel S,Svantesson M,Benbenishty J,Maia PA,Beishuizen A,Cohen S,Nalos D

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:The aim of our study was to explore, using an innovative method, the effect of temporal changes in the mortality prediction performance of an existing model on the quality of care assessment. The prognostic model (rSAPS-II) was a recalibrated Simplified Acute Physiology Score-II model developed for very elderly...

journal_title：Intensive care medicine

authors： Minne L,Eslami S,de Keizer N,de Jonge E,de Rooij SE,Abu-Hanna A

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:The primary objective was to test the hypothesis that clinical re-expansion pulmonary edema is predominantly due to increased permeability of the alveolar-capillary barrier. A secondary objective was to determine if the alveolar epithelium was functionally intact in patients with re-expansion pulmonary edema ...

journal_title：Intensive care medicine

authors： Sue RD,Matthay MA,Ware LB

更新日期：2004-10-01 00:00:00

abstract：PURPOSE:Severe acute pancreatitis (SAP) remains a life-threatening disease with classic etiology of systemic inflammatory response and mortality between 30 and 50 %. The aim of the present study is to compare two different treatment strategies of goal-directed hemodynamic management and evaluate their impact on surviva...

journal_title：Intensive care medicine

authors： Trepte CJ,Bachmann KA,Stork JH,Friedheim TJ,Hinsch A,Goepfert MS,Mann O,Izbicki JR,Goetz AE,Reuter DA

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:The efficacy of noninvasive continuous positive airway pressure (CPAP) to improve outcomes in severe hypoxemic acute respiratory failure (hARF) due to pneumonia has not been clearly established. The aim of this study was to compare CPAP vs. oxygen therapy to reduce the risk of meeting criteria for endotracheal ...

journal_title：Intensive care medicine

authors： Brambilla AM,Aliberti S,Prina E,Nicoli F,Del Forno M,Nava S,Ferrari G,Corradi F,Pelosi P,Bignamini A,Tarsia P,Cosentini R

更新日期：2014-07-01 00:00:00

abstract：:Pulmonary artery (PA) catheterization is now a routine procedure in the care of critically ill patients. We report a case in which a pulmonary artery catheter was a major factor in the demise of a patient who developed adult respiratory distress syndrome following a septic abortion. ...

journal_title：Intensive care medicine

authors： Melton JG,Kamal GD

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:We tested the hypothesis that synchronization to patient effort during intermittent mandatory ventilation (SIMV), when compared to conventional unsynchronized intermittent mandatory ventilation (IMV), will decrease energy expenditure, as reflected by decreased oxygen consumption (VO2). DESIGN:We used a four-...

journal_title：Intensive care medicine

authors： Smith KM,Wahlig TM,Bing DR,Georgieff MK,Boros SJ,Mammel MC

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To investigate the efficacy of somatostatin for the treatment of severe acute pancreatitis. DESIGN:Prospective, randomized and unblinded study. SETTING:A general intensive care unit (ICU) in a university hospital. PATIENTS:50 patients with severe acute pancreatitis. INTERVENTIONS:All patients received the...

journal_title：Intensive care medicine

authors： Planas M,Pérez A,Iglesia R,Porta I,Masclans JR,Bermejo B

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:To examine the attitudes of the general public regarding who should decide about the withdrawal of life support and to compare these attitudes with those of intensive care personnel. DESIGN:Nationwide postal questionnaire survey. SETTING:Sweden. PARTICIPANTS:One thousand one hundred ninety-six randomly sel...

journal_title：Intensive care medicine

authors： Sjökvist P,Nilstun T,Svantesson M,Berggren L

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:A readily available assessment of changes in pleural pressure would be useful for ventilator and fluid management in critically ill patients. We examined whether changes in pulmonary artery occlusion pressure (Ppao) adequately reflect respiratory changes in pleural pressure as assessed by changes in intraesop...

journal_title：Intensive care medicine

authors： Bellemare P,Goldberg P,Magder SA

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:(a) To assess whether differences in lung morphology observed in patients with adult respiratory distress syndrome (ARDS) are associated with differences in cardiorespiratory parameters, lung mechanics, and outcome. (b) To propose a new ARDS Severity Score to identify patients with a high mortality risk. DE...

journal_title：Intensive care medicine

authors： Rouby JJ,Puybasset L,Cluzel P,Richecoeur J,Lu Q,Grenier P

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:Inhalation of high concentrations of nitric oxide (NO) has been shown to improve gas exchange and to reduce pulmonary vascular resistance in individuals with ischemia-reperfusion injury following orthotopic lung transplantation. We assessed the cardiopulmonary effects of low doses of NO in early allograft dys...

journal_title：Intensive care medicine

authors： Kemming GI,Merkel MJ,Schallerer A,Habler OP,Kleen MS,Haller M,Briegel J,Vogelmeier C,Fürst H,Reichart B,Zwissler B

更新日期：1998-11-01 00:00:00

abstract：:A retrospective study of the medical records of 115 consecutive cases of meningococcal disease with 11 fatalities was carried out in order to evaluate the power of 15 clinical and laboratory variables available on admission in predicting a fatal outcome. On linear discriminant analysis, six variables showed a signific...

journal_title：Intensive care medicine

authors： Gårdlund B

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficiency of a new device developed to remove obstructions from endotracheal tubes (ETT) in mechanically ventilated patients. DESIGN:Open study in mechanically ventilated sedated and paralyzed ICU patients. SETTING:General ICU and Laboratory of Respiratory Mechanics of the University of Rom...

journal_title：Intensive care medicine

authors： Conti G,Rocco M,De Blasi RA,Lappa A,Antonelli M,Bufi M,Gasparetto A

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of nicotinamide (NIC), an inhibitor of poly(ADP-ribose) synthetase (PARS), on intestinal and liver perfusion, O2 kinetics, and energy metabolism over 24 h of hyperdynamic porcine endotoxemia. DESIGN:Prospective, randomized, controlled experimental study with repeated measures. SET...

journal_title：Intensive care medicine

authors： Theisen M,Träger K,Tugtekin I,Stehr A,Ploner F,Georgieff M,Radermacher P,Matĕjovic M

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:We propose that higher airway occlusion pressure (P0.1) responses to hypercapnic challenge (HC) indicate less severe injury. The study aim was to determine whether P0.1 responses to HC were associated with successful weaning after prolonged mechanical ventilation (PMV) in patients with brainstem lesions and t...

journal_title：Intensive care medicine

authors： Wu YK,Lee CH,Shia BC,Tsai YH,Tsao TC

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To investigate the correlation between microalbuminuria and extravascular lung water in patients in septic shock who require mechanical ventilation for severe respiratory failure. DESIGN AND SETTING:Prospective, observational, clinical study in the 20-bed intensive care unit of a university hospital. PATIEN...

journal_title：Intensive care medicine

authors： Molnár Z,Szakmány T,Heigl P

更新日期：2003-03-01 00:00:00

abstract：:Risk of critical illness is determined both by genetic and environmental influences, particularly those relating to infectious and cardiovascular diseases. Physiologically-based scoring systems cannot measure prior risk because they do not quantify physiological reserve independently of the acute illness. Genetic prof...

journal_title：Intensive care medicine

authors： Bion JF

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:The interchangeability of continuous measurement of cardiac output (CO) with the traditional bolus method in patients after cardiopulmonary bypass (CPB) is uncertain. DESIGN:Prospective observational clinical study. SETTING:A 20-bed surgical ICU at a university hospital. PATIENTS:Fourteen deeply sedated, v...

journal_title：Intensive care medicine

authors： Bendjelid K,Schütz N,Suter PM,Romand JA

更新日期：2006-06-01 00:00:00

abstract：:In a randomized clinical trial the prophylactic effects of locally administered antimicrobials on quantitative colonization and respiratory infections were studied in intubated patients with an expected period of mechanical ventilation of greater than 6 days. Nineteen patients received 50 mg of polymyxin B and 80 mg o...

journal_title：Intensive care medicine

authors： Unertl K,Ruckdeschel G,Selbmann HK,Jensen U,Forst H,Lenhart FP,Peter K

更新日期：1987-01-01 00:00:00

abstract：:A randomized study of 30 patients undergoing uncomplicated surgery under spinal anesthesia was conducted to assess the influence of colloids on the kinetics of plasma fibronectin and complement. Both are opsonins of the reticuloendothelial system; moreover fibronectin is concerned with host resistance against septic c...

journal_title：Intensive care medicine

authors： Vedrinne JM,Hoen JP,Bussery D,Veyssere C,Richard M,Motin J

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To assess if the observed respiratory cycle-related variation in intra-abdominal pressure is reliably quantifiable and a possible indirect indicator of abdominal compliance. Secondary issues were to assess the roles played by respiratory parameters in determining this oscillation and by patients' position in ...

journal_title：Intensive care medicine

authors： Sturini E,Saporito A,Sugrue M,Parr MJ,Bishop G,Braschi A

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To identify and reduce medication-prescribing errors by introducing systematic physician education and post-cardiac surgery admission prescription forms. DESIGN:Errors were defined as: incomplete prescriptions; potential adverse drug events (ADEs), i.e. either intercepted or non-intercepted incorrect prescri...

journal_title：Intensive care medicine

authors： Burmester MK,Dionne R,Thiagarajan RR,Laussen PC

更新日期：2008-06-01 00:00:00