Oxygenation index, an indicator of optimal distending pressure during high-frequency oscillatory ventilation?

abstract：:During the last two decades, severe group A beta-haemolytic streptococcal infections have been defined as the "toxic strep syndrome", and have been reported not only in immunocompromised or elderly people, but also occasionally in previously healthy patients. We describe 4 patients presenting with the toxic strep synd...

journal_title：Intensive care medicine

authors： Soravia C,Romand JA,Herrmann M,Chevrolet JC,Ricou B,Suter PM

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To identify and reduce medication-prescribing errors by introducing systematic physician education and post-cardiac surgery admission prescription forms. DESIGN:Errors were defined as: incomplete prescriptions; potential adverse drug events (ADEs), i.e. either intercepted or non-intercepted incorrect prescri...

journal_title：Intensive care medicine

authors： Burmester MK,Dionne R,Thiagarajan RR,Laussen PC

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between the base deficit value in the immediate postoperative period of coronary surgery for cardiopulmonary bypass and the length of stay in the ICU. DESIGN AND SETTING:Prospective descriptive study in the department of anesthesia and cardiovascular surgery of a university hospita...

journal_title：Intensive care medicine

authors： Hugot P,Sicsic JC,Schaffuser A,Sellin M,Corbineau H,Chaperon J,Ecoffey C

更新日期：2003-02-01 00:00:00

abstract：PURPOSE:Hyperglycaemia is common in the critically ill. The objectives of this study were to determine the prevalence of critical illness-associated hyperglycaemia (CIAH) and recognised and unrecognised diabetes in the critically ill as well as to evaluate the impact of premorbid glycaemia on the association between ac...

journal_title：Intensive care medicine

authors： Plummer MP,Bellomo R,Cousins CE,Annink CE,Sundararajan K,Reddi BA,Raj JP,Chapman MJ,Horowitz M,Deane AM

更新日期：2014-07-01 00:00:00

abstract：:Nine patients hospitalized for tetanus were studied under the same protocol which included two haemodynamic studies with a preload trial (PLT). The first being made during therapy (diazepam barbiturate association), on the sixth day of hospitalisation, and the second one after recovery. The comparison of the results s...

journal_title：Intensive care medicine

authors： Desjars P,Pinaud M,Baron D,Rodineau P,Nicolas R

更新日期：1978-07-01 00:00:00

abstract：OBJECTIVE:The Guillain-Barré syndrome (GBS) is an acute inflammatory polyneuropathy related to autoimmunity. However, no conclusive etiological concept has yet been found. We examined the variation in autoantibodies to lipids in serum of GBS patients in response to the course of the disease but investigated titer modif...

journal_title：Intensive care medicine

authors： Nakos G,Tziakou E,Maneta-Peyret L,Nassis C,Lekka ME

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of screening strategy and contact precautions for patients with methicillin-resistant Staphylococcus aureus (MRSA). DESIGN AND SETTING:Prospective observational cohort from 1 February 1995 to 31 December 2001 in three intensive care units (45 beds) in a French teaching hospital....

journal_title：Intensive care medicine

authors： Lucet JC,Paoletti X,Lolom I,Paugam-Burtz C,Trouillet JL,Timsit JF,Deblangy C,Andremont A,Regnier B

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVES:Inhalation of nitric oxide (NO) selectively dilates pulmonary vessels in well-ventilated regions. Prostaglandin F2 alpha (PGF2 alpha) is a vasoconstrictor and is reported to enhance hypoxic pulmonary vasoconstriction. The objective of this study was to examine whether the combination of intravenous PGF2 alph...

journal_title：Intensive care medicine

authors： Kobayashi H,Tanaka N,Winkler M,Zapol WM

更新日期：1996-07-01 00:00:00

abstract：:Specific regulations regarding oversight of research in children vary from country to country, but most share common principles derived from major consensus documents. Whereas the permissibility of research on adults depends heavily upon the informed consent of the subject, the regulation of research in pediatrics is ...

journal_title：Intensive care medicine

authors： Truog RD

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the origin of H+ ions participating in the generation of CO2 coming from sodium bicarbonate infusion during metabolic acidosis. We hypothesized that these H+ ions come from a back-titration of the main non-bicarbonate buffers present in the blood, i. e. the hemoglobin and the albumin, and thus pos...

journal_title：Intensive care medicine

authors： Levraut J,Garcia P,Giunti C,Ichai C,Bouregba M,Ciebiera JP,Payan P,Grimaud D

更新日期：2000-05-01 00:00:00

abstract：:Sixteen anaesthetized rabbits were subjected to tracheostomy and lung damage produced by the instillation of 4.5 ml/kg hydrochloric acid (pH 1.5) into the trachea. Half of the animals were ventilated with a positive end-expiratory pressure (PEEP) of 3 cmH2O and half with a PEEP of 10 cmH2O for 5 h, the mean airway pre...

journal_title：Intensive care medicine

authors： Sohma A,Brampton WJ,Dunnill MS,Sykes MK

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To investigate the involvement of intestinal angiotensin II type 2 receptors in the outcome of acute severe hypovolemia as well as systemic and regional mesenteric hemodynamics and intestinal mucosal functions in anesthetized pigs. DESIGN AND SETTING:Prospective, interventional animal study in a university r...

journal_title：Intensive care medicine

authors： Laesser M,Spak E,Ewert S,Aneman A,Fandriks L

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:To analyze the actual cost of pediatric intensive care and its different components, particularly the differences between various patient groups, with special reference to the variable cost and the elements included in it. DESIGN:Prospective, observational study. SETTING:Multidisciplinary 12-bed pediatric i...

journal_title：Intensive care medicine

authors： García S,Ruza F,Alvarado F,Madero R,Delgado MA,Dorao P,Frias M

更新日期：1997-02-01 00:00:00

abstract：PURPOSE:Patients undergoing cardiac surgery often require transfusions of red blood cells, plasma and platelets. These components differ widely in both indications for use and composition. However, from a statistical point of view there is a significant colinearity between the components. This study explores the relati...

journal_title：Intensive care medicine

authors： Bjursten H,Dardashti A,Ederoth P,Brondén B,Algotsson L

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of some acid-base abnormalities on blood capacity of transporting CO(2). DESIGN:Prospective study. SETTING:General and Cardiosurgical ICUs of a University hospital. PATIENTS:Six groups of ten patients characterized by: metabolic alkalosis; respiratory alkalosis; absence of acid-b...

journal_title：Intensive care medicine

authors： Cavaliere F,Antonelli M,Arcangeli A,Conti G,Pennisi MA,Proietti R

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To measure water balance and changes in distribution, and the effect of giving supplementary albumin, early after a burn injury. DESIGN:Consecutive patients (matched groups) and healthy controls. SETTING:National burn unit in a Swedish university hospital. PATIENTS AND SUBJECTS:Eighteen patients with 18%-9...

journal_title：Intensive care medicine

authors： Zdolsek HJ,Lisander B,Jones AW,Sjöberg F

更新日期：2001-05-01 00:00:00

abstract：:608 patients admitted to a general Intensive Care Unit (ICU) over a 30 month period were analyzed according to the Apache II Severity of Disease Classification System on day one of admission. Hospital outcome details were available on 583 patients in the series. The mean Apache II scores for survivors (396) and non-su...

journal_title：Intensive care medicine

authors： Jacobs S,Chang RW,Lee B,Lee B

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To assess the impact of hemodynamic variables on the outcome of critically ill patients in septic shock and to identify the optimal threshold values related to outcome with special reference to continuously monitored mean arterial pressure (MAP) and mixed venous oxygen saturation (SvO2). DESIGN AND SETTING:R...

journal_title：Intensive care medicine

authors： Varpula M,Tallgren M,Saukkonen K,Voipio-Pulkki LM,Pettilä V

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:Growing evidence suggests that acute respiratory distress syndrome (ARDS) occurring as a consequence of primary (direct) lung injury differs from that resulting from secondary (indirect) lung injury in terms of radiographic appearance, response to interventions, and outcomes. We examined whether there are dif...

journal_title：Intensive care medicine

authors： Parker CM,Heyland DK,Groll D,Caeser M

更新日期：2006-11-01 00:00:00

abstract：:A prospective study of thiamine status in patients with severe injuries (injury severity scores greater than 12) showed that they all developed signs of severe thiamine deficiency on the basis of transketolase activity, the standard biochemical test for thiamine deficiency. This occurred within the first week after th...

journal_title：Intensive care medicine

authors： McConachie I,Haskew A

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:Nuclear factor-kappaB (NF-kappaB) is a transcription factor which plays a pivotal role in the induction of genes involved in the response to injury and inflammation. Calpain I inhibitor is a potent antioxidant which is an effective inhibitor of NF-kappaB. This study examined whether the postulate that calpain...

journal_title：Intensive care medicine

authors： Virlos I,Mazzon E,Serraino I,Genovese T,Di Paola R,Thiemerman C,Siriwardena A,Cuzzocrea S

更新日期：2004-08-01 00:00:00

abstract：:Arrhythmias are extremely common early after AMI. An arrhythmia is defined by exclusion, either because the sequence of myocardial depolarisation is other than normal or because certain arbitrary limits are exceeded. It follows that the term "arrhythmia" encompasses a complex heterogenous group. Although arrhythmias a...

journal_title：Intensive care medicine

authors： Rowlands DJ

更新日期：1978-01-01 00:00:00

abstract：OBJECTIVE:To investigate the theoretical interactions between ventilator settings, tracheal gas insufflation (TGI), and alveolar ventilation. DESIGN:We derived differential equations governing compartmental volume changes in a one-compartment model of TGI-assisted ventilation and equations governing gas dilution in th...

journal_title：Intensive care medicine

authors： Hotchkiss JR Jr,Crooke PS 3rd,Marini JJ

更新日期：1996-10-01 00:00:00

abstract：PURPOSE:To test the hypothesis that RNA editing is altered in pediatric patients with cyanotic congenital heart disease (CHD) and to determine whether A-to-I RNA editing is associated with the postoperative course following cardiac surgery. Cyanotic CHD is associated with a unique pathophysiology caused by chronic hypo...

journal_title：Intensive care medicine

authors： Borik S,Simon AJ,Nevo-Caspi Y,Mishali D,Amariglio N,Rechavi G,Paret G

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:We compared hemodynamic and biological effects of the Cascade system, which uses very high volume hemofiltration (HVHF) (120 mL kg(-1) h(-1)), with those of usual care in patients with septic shock. METHODS:Multicenter, prospective, randomized, open-label trial in three intensive care units (ICU). Adults with ...

journal_title：Intensive care medicine

authors： Quenot JP,Binquet C,Vinsonneau C,Barbar SD,Vinault S,Deckert V,Lemaire S,Hassain AA,Bruyère R,Souweine B,Lagrost L,Adrie C

更新日期：2015-12-01 00:00:00

abstract：:The spread of a multi-resistant glucose-acidifying Acinetobacter calcoaceticus strain in a community hospital was studied. After admission of a colonized patient to the hospital the strain was found in clinical specimens from ICU patients and subsequently from several of these patients after transfer to medical wards....

journal_title：Intensive care medicine

authors： Crombach WH,Dijkshoorn L,van Noort-Klaassen M,Niessen J,van Knippenberg-Gordebeke G

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To determine the global metabolomic profile as measured in circulating plasma from surviving and non-surviving patients with community-acquired pneumonia (CAP) and sepsis. METHODS:Random, outcome-stratified case-control sample from a prospective study of 1,895 patients hospitalized with CAP and sepsis. Cases (...

journal_title：Intensive care medicine

authors： Seymour CW,Yende S,Scott MJ,Pribis J,Mohney RP,Bell LN,Chen YF,Zuckerbraun BS,Bigbee WL,Yealy DM,Weissfeld L,Kellum JA,Angus DC

更新日期：2013-08-01 00:00:00

abstract：:In a randomized clinical trial the prophylactic effects of locally administered antimicrobials on quantitative colonization and respiratory infections were studied in intubated patients with an expected period of mechanical ventilation of greater than 6 days. Nineteen patients received 50 mg of polymyxin B and 80 mg o...

journal_title：Intensive care medicine

authors： Unertl K,Ruckdeschel G,Selbmann HK,Jensen U,Forst H,Lenhart FP,Peter K

更新日期：1987-01-01 00:00:00

abstract：:We investigated the levels of auto-PEEP and dynamic hyperinflation during high frequency jet ventilation (HFJV) and controlled mechanical ventilation (CMV) in six patients with chronic obstructive pulmonary disease within the first 36 h of acute exacerbation. The comparative evaluation was performed at similar conditi...

journal_title：Intensive care medicine

authors： Conti G,Bufi M,Rocco M,Calzecchi E,De Blasi RA,Antonelli M,Pelaia P,Gasparetto A

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and the circumstances of a moderate increase in serum creatinine early after elective abdominal aortic surgery. DESIGN:Prospective clinical observational study. SETTING:Surgical intensive care unit in a university hospital. PATIENTS:Two hundred and fifteen consecutive adult patien...

journal_title：Intensive care medicine

authors： Ryckwaert F,Alric P,Picot MC,Djoufelkit K,Colson P

更新日期：2003-10-01 00:00:00