Incidence and circumstances of serum creatinine increase after abdominal aortic surgery.

Abstract:

OBJECTIVE:To evaluate the incidence and the circumstances of a moderate increase in serum creatinine early after elective abdominal aortic surgery. DESIGN:Prospective clinical observational study. SETTING:Surgical intensive care unit in a university hospital. PATIENTS:Two hundred and fifteen consecutive adult patients operated on for infra-renal abdominal aortic surgery during 1 year. INTERVENTIONS:A moderate increase in plasma creatinine of 20% from preoperative value (renal dysfunction, RD) was systematically recorded during the first 3 days following surgery. Organ dysfunctions (cardiac, pulmonary, haematological, and neurological) were assessed. MEASUREMENTS AND RESULTS:Forty-three patients (20%) experienced a postoperative RD; six of these required dialysis. RD was associated with other organ dysfunctions in 60.5% patients. Mortality rate was significantly higher for patients who had a RD, than patients without RD (9.3% vs 1.2%, P<0.02). Mean ICU stay of patients with RD was significantly longer (7.9+/-5.6 days vs 5.0+/-1.8 days, P<0.01). However, patients with RD but without other organ dysfunctions had a mortality rate of 0% and did not have a significantly longer stay in ICU than patients without any organ dysfunctions (5.2+/-2.1 days vs 4.6+/-1.2 days, P=0.09). CONCLUSION:Our results suggest that a postoperative 20%-increase in plasma creatinine after abdominal aortic surgery is not rare and occurs frequently with other organ dysfunction.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Ryckwaert F,Alric P,Picot MC,Djoufelkit K,Colson P

doi

10.1007/s00134-003-1958-x

keywords:

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

1821-4

issue

10

eissn

0342-4642

issn

1432-1238

journal_volume

29

pub_type

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