当前位置： SCI文献检索 > INTENSIVE CARE MEDICINE期刊下所有文献 > Five-year cost-utility analysis of acute renal replacement therapy: a societal perspective.

Five-year cost-utility analysis of acute renal replacement therapy: a societal perspective.

Abstract：

PURPOSE:Assessment of the cost utility (CU) of acute renal replacement therapy (RRT) from a societal perspective during a 5-year follow-up. METHODS:This was a cross-sectional cohort study in a medical-surgical intensive care unit and an acute RRT unit of 410 consecutive patients treated with acute RRT in Helsinki University Hospital in 2000-2002. Five-year survival and health-related quality of life (HRQoL) were assessed and used to calculate quality-adjusted life years (QALYs) in two ways. They were first calculated for the 5-year follow-up period and, second, estimated for the expected lifetime. HRQoL was assessed by the EuroQol (EQ-5D) in 2003. The cost analysis included hospital costs during index hospitalization along with hospital and societal costs for the following 5 years. The CU ratio was determined as total costs divided by gained QALYs. RESULTS:Median survival time for all patients was 0.20 years and the EQ-5D index score was 0.68, 0.18 lower than that of the age- and gender-matched general population. All RRT-treated patients gained 0.10 QALYs/patient and hospital survivors 2.54 QALYs in 5 years. Overall the CU ratio was poor [5 year median 271,116 (29,782-2,177,581) €/QALY]. However, it was acceptable (less than 50,000 €/QALY) in patients who survived for more than a year and did not need chronic RRT. Cost utility decreased with increasing age exceeding 1.0 million €QALY in the older groups. CONCLUSIONS:In general, the CU ratio of acute RRT is poor. However, it is acceptable in patients with renal recovery who survive for more than 1 year.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Laukkanen A,Emaus L,Pettilä V,Kaukonen KM

doi

10.1007/s00134-012-2760-4

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

406-13

issue

3

eissn

0342-4642

issn

1432-1238

journal_volume

39

pub_type

杂志文章

相关文献

INTENSIVE CARE MEDICINE文献大全
  • Cardiac arrest due to oral potassium intake.

    abstract：:A 29-year-old woman suffered a cardiac arrest, due to profound hyperkalaemia, caused by the use of a potassium-containing salt substitute. She was resuscitated, but post-hypoxic brain damage occurred. Some of the sparse literature is reviewed. ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/BF00255641

    authors： Schim van der Loeff HJ,Strack van Schijndel RJ,Thijs LG

    更新日期：1988-01-01 00:00:00

  • Position paper of the ESICM Working Group on Nutrition and Metabolism. Metabolic basis of nutrition in intensive care unit patients: ten critical questions.

    abstract：:The metabolic changes associated with critical illness involve several pathways acting at different steps of the utilization of nutritive substrates. The understanding of the role of these pathways and of their complex regulation has led to the development of new strategies for the metabolic and nutritional management...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-002-1512-2

    authors： Biolo G,Grimble G,Preiser JC,Leverve X,Jolliet P,Planas M,Roth E,Wernerman J,Pichard C,European Society of Intensive Care Medicine Working Group on Nutrition and Metabolism.

    更新日期：2002-11-01 00:00:00

  • Acute respiratory distress syndrome among trauma patients: trends in ICU mortality, risk factors, complications and resource utilization.

    abstract：OBJECTIVE:To evaluate trends in mortality and related factors among trauma patients who developed acute respiratory distress syndrome (ARDS). STUDY:Observational study based on data prospectively gathered in computerized trauma registry. SETTING:Trauma intensive care unit (ICU) of 48 beds in level I trauma center. P...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340100955

    authors： Navarrete-Navarro P,Rodriguez A,Reynolds N,West R,Habashi N,Rivera R,Chiu WC,Scalea T

    更新日期：2001-07-01 00:00:00

  • Sonoclot signature during normal pregnancy.

    abstract：OBJECTIVE:The Sonoclot analyser provides global measurement of haemostasis, including plasma coagulation, platelet function and fibrinolysis. Benefits of its use in cardiovascular and hepatic surgery are well-documented and it may be useful in managing obstetric complications. The aim of this study was to determine ran...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340050047

    authors： Kjellberg U,Hellgren M

    更新日期：2000-02-01 00:00:00

  • Effects of pulmonary blood volume on vascular reactivity in the lung.

    abstract：OBJECTIVE:Pulmonary flow resistance is mainly determined by vessel calibres, resulting from the interaction of volume-passive distension and active vasomotion. However, quantitative information on the interplay between these counteracting forces in the lung is lacking. Therefore, we aimed at quantifying (1) the effects...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340051090

    authors： Ding ZP,Scheeren TW,Arndt JO

    更新日期：1999-12-01 00:00:00

  • Inhibition of human neutrophil chemotaxis toward interleukin 8 with six clinical antithrombin concentrates in vitro.

    abstract：OBJECTIVE:Antithrombin exerts direct effects on neutrophils by inhibiting chemokine-induced migration. This study examined the potency of different pharmaceutical antithrombin preparations in inhibiting neutrophil chemotaxis toward interleukin 8. METHODS:Cell migration was tested by the leading front assay in modified...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-002-1432-1

    authors： Kaneider NC,Rabensteiner A,Reinisch CM,Dunzendorfer S,Wiedermann CJ

    更新日期：2002-10-01 00:00:00

  • Acute respiratory distress syndrome mimickers lacking common risk factors of the Berlin definition.

    abstract：PURPOSE:Some patients presenting with acute respiratory failure and meeting the Berlin criteria for acute respiratory distress syndrome (ARDS) lack exposure to common risk factors (CRF). These so-called ARDS mimickers often lack histological diffuse alveolar damage. We aimed to describe such ARDS mimickers lacking CRF ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-015-4064-y

    authors： Gibelin A,Parrot A,Maitre B,Brun-Buisson C,Mekontso Dessap A,Fartoukh M,de Prost N

    更新日期：2016-02-01 00:00:00

  • Procalcitonin for early diagnosis and differentiation of SIRS, sepsis, severe sepsis, and septic shock.

    abstract：OBJECTIVE:To determine the value of procalcitonin (PCT) in the early diagnosis (and differentiation) of patients with SIRS, sepsis, severe sepsis, and septic shock in comparison to C-reactive protein (CRP), white blood cell and thrombocyte count, and APACHE-II score (AP-II). DESIGN:Prospective cohort study including a...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF02900728

    authors： Brunkhorst FM,Wegscheider K,Forycki ZF,Brunkhorst R

    更新日期：2000-03-01 00:00:00

  • Management of autonomic dysfunction in severe tetanus: the use of magnesium sulphate and clonidine.

    abstract：:The treatment of severe tetanus with autonomic dysfunction is discussed, with emphasis on the use of magnesium sulphate. An exemplary case is reported, describing the inadequate response to magnesium, but the previously unreported and successful use of clonidine to control sympathetic overactivity. The properties of c...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/BF02575297

    authors： Sutton DN,Tremlett MR,Woodcock TE,Nielsen MS

    更新日期：1990-01-01 00:00:00

  • Comparison of electrocardiograms recorded with standard leads and derived from the vectorcardiographic frank leads in high risk patients.

    abstract：:Dynamic vectorcardiography (VCG) is increasingly employed for ischaemia monitoring with the use of a computerized method for recording and on-line analysis by the calculation of trend parameters. To elucidate how well the derived electrocardiogram (dECG), calculated from the VCG, compares with the simultaneously regis...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章

    doi：10.1007/s001340050455

    authors： Gannedahl PE,Ljungqvist OH,Lundin P,Edner M

    更新日期：1997-10-01 00:00:00

  • Carbamylated erythropoietin-FC fusion protein and recombinant human erythropoietin during porcine kidney ischemia/reperfusion injury.

    abstract：PURPOSE:To test the hypothesis that a carbamylated EPO-FC fusion protein (cEPO-FC) or recombinant human erythropoietin (rhEPO) would protect against kidney ischemia/reperfusion (I/R) injury in pigs with atherosclerosis. METHODS:Anesthetized and mechanically ventilated animals received cEPO-FC (50 μg kg(-1)), rhEPO (5,...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2766-y

    authors： Matějková Š,Scheuerle A,Wagner F,McCook O,Matallo J,Gröger M,Seifritz A,Stahl B,Vcelar B,Calzia E,Georgieff M,Möller P,Schelzig H,Radermacher P,Simon F

    更新日期：2013-03-01 00:00:00

  • Retrieval of critically ill adults using extracorporeal membrane oxygenation: an Australian experience.

    abstract：PURPOSE:A retrieval program was developed in New South Wales (NSW), Australia to provide extracorporeal membrane oxygenation support (ECMO) for the safe transport of adults with severe, acute respiratory or cardiac failure. We describe the development and results of this program and the impact of the 2009 H1N1 epidemic...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-011-2158-8

    authors： Forrest P,Ratchford J,Burns B,Herkes R,Jackson A,Plunkett B,Torzillo P,Nair P,Granger E,Wilson M,Pye R

    更新日期：2011-05-01 00:00:00

  • Amrinone for refractory cardiogenic shock following chloroquine poisoning.

    abstract：:Cardiac arrhythmias and circulatory collapse account for the high mortality reported after severe chloroquine poisoning. We have recently observed a 17-year-old man who ingested an 8 g chloroquine overdose. Cardiac arrest occurred within 1 h. Cardiogenic shock was refractory to epinephrine, dopamine and molar sodium l...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01720684

    authors： Hantson P,Ronveau JL,De Coninck B,Horn JL,Mahieu P,Hassoun A

    更新日期：1991-01-01 00:00:00

  • Life-threatening hyperkalaemia following therapeutic barbiturate coma.

    abstract：OBJECTIVE:To report the occurrence of life-threatening hyperkalaemia following treatment with therapeutic thiopentone coma. SETTING:The neurosurgical intensive care units of Royal North Shore Hospital and Liverpool Hospital, Sydney, Australia. PATIENTS:Three patients treated with theraputic thiopentone coma. One pati...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-002-1399-y

    authors： Cairns CJ,Thomas B,Fletcher S,Parr MJ,Finfer SR

    更新日期：2002-09-01 00:00:00

  • Validation of pediatric index of mortality 2 (PIM2) in a single pediatric intensive care unit in Japan.

    abstract：OBJECTIVE:The Pediatric Index of Mortality 2 (PIM2), one of the key mortality prediction models for children in intensive care units, has not been validated in Japan. The purpose of this study was to validate the performance of PIM2 in a population of patients admitted to one pediatric intensive care unit (PICU) in Jap...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-011-2460-5

    authors： Imamura T,Nakagawa S,Goldman RD,Fujiwara T

    更新日期：2012-04-01 00:00:00

  • The safety and efficacy of sustained inflations as a lung recruitment maneuver in pediatric intensive care unit patients.

    abstract：OBJECTIVE:To assess the safety and efficacy of sustained inflations (SI) as lung recruitment maneuvers (RMs) in ventilated pediatric intensive care unit (PICU) patients. DESIGN:Observational, prospective data collection. SETTING:Tertiary-care PICU. PATIENTS AND PARTICIPANTS:Thirty-two consecutive ventilated pediatri...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-007-0764-2

    authors： Duff JP,Rosychuk RJ,Joffe AR

    更新日期：2007-10-01 00:00:00

  • Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough.

    abstract：BACKGROUND:It remains uncertain why immunocompetent patients with bacterial community-acquired pneumonia (CAP) die, in spite of adequate antibiotics. METHODS:This is a secondary analysis of the CAPUCI database which was a prospective observational multicentre study. Two hundred and twelve immunocompetent patients admi...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-008-1363-6

    authors： Rodriguez A,Lisboa T,Blot S,Martin-Loeches I,Solé-Violan J,De Mendoza D,Rello J,Community-Acquired Pneumonia Intensive Care Units (CAPUCI) Study Investigators.

    更新日期：2009-03-01 00:00:00

  • Ventilator-associated pneumonia in children after cardiac surgery in The Netherlands.

    abstract：PURPOSE:We conducted a retrospective cohort study in an academic tertiary care center to characterize ventilator-associated pneumonia (VAP) in pediatric patients after cardiac surgery in The Netherlands. METHODS:All patients following cardiac surgery and mechanically ventilated for ≥24 h were included. The primary out...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-011-2349-3

    authors： Roeleveld PP,Guijt D,Kuijper EJ,Hazekamp MG,de Wilde RB,de Jonge E

    更新日期：2011-10-01 00:00:00

  • Risk of Clostridium difficile diarrhoea in critically ill patients treated with erythromycin-based prokinetic therapy for feed intolerance.

    abstract：OBJECTIVE:To determine the incidence of Clostridium difficile (CD) diarrhoea in feed-intolerant, critically ill patients who received erythromycin-based prokinetic therapy. DESIGN AND SETTING:Prospective observational study in a mixed intensive care unit. METHODS:The development of diarrhoea (> 3 loose, liquid stool ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-007-0834-5

    authors： Nguyen NQ,Ching K,Fraser RJ,Chapman MJ,Holloway RH

    更新日期：2008-01-01 00:00:00

  • Profound and persistent decrease of circulating dendritic cells is associated with ICU-acquired infection in patients with septic shock.

    abstract：PURPOSE:Septic shock induces a decrease in dendritic cells (DCs) that may contribute to sepsis-induced immunosuppression. We analyzed the time course of circulating DCs in patients with septic shock and its relation to susceptibility to intensive care unit (ICU)-acquired infections. METHODS:We enrolled adult patients ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-011-2306-1

    authors： Grimaldi D,Louis S,Pène F,Sirgo G,Rousseau C,Claessens YE,Vimeux L,Cariou A,Mira JP,Hosmalin A,Chiche JD

    更新日期：2011-09-01 00:00:00

  • Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis.

    abstract：PURPOSE:Polymyxin B-immobilized hemoperfusion (PMX-HP) is an adjuvant therapy for sepsis or septic shock that clears circulating endotoxin. Prior trials have shown that PMX-HP improves surrogate endpoints. We aimed to conduct an evidence synthesis to evaluate the efficacy and safety of PMX-HP in critically ill adult pa...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,meta分析

    doi：10.1007/s00134-017-5004-9

    authors： Fujii T,Ganeko R,Kataoka Y,Furukawa TA,Featherstone R,Doi K,Vincent JL,Pasero D,Robert R,Ronco C,Bagshaw SM

    更新日期：2018-02-01 00:00:00

  • Could resuscitation be based on microcirculation data? We are not sure.

    abstract：: ...

    journal_title：Intensive care medicine

    pub_type： 信件

    doi：10.1007/s00134-018-5180-2

    authors： Monnet X,Saugel B

    更新日期：2018-06-01 00:00:00

  • Nine equivalents of nursing manpower use score (NEMS).

    abstract：OBJECTIVES:To develop a simplified Therapeutic Intervention Scoring System (TISS) based on the TISS-28 items and to validate the new score in an independent database. DESIGN:Retrospective statistical analysis of a database and a prospective multicentre study. SETTING:Development in the database of the Foundation for ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340050406

    authors： Reis Miranda D,Moreno R,Iapichino G

    更新日期：1997-07-01 00:00:00

  • Apoptosis inhibition in P. aeruginosa-induced lung injury influences lung fluid balance.

    abstract：OBJECTIVE:Pseudomonas aeruginosa-induced lung injury is characterized not only by the alteration in lung fluid movement but also by apoptosis of lung epithelial and endothelial cells. We studied whether inhibition of apoptosis using a broad spectrum caspase inhibitor, benzyloxycarbonyl-Val-Ala-Asp fluoromethylketone (Z...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-004-2165-0

    authors： Le Berre R,Faure K,Fauvel H,Viget NB,Ader F,Prangère T,Thomas AM,Leroy X,Pittet JF,Marchetti P,Guery BP

    更新日期：2004-06-01 00:00:00

  • Measurement of lung volume in mechanically ventilated monkeys with an ultrasonic flow meter and the nitrogen washout method.

    abstract：OBJECTIVE:Measurement of functional residual capacity (FRC) during mechanical ventilation is important to standardise respiratory system compliance and adjust the ventilator settings to optimise lung recruitment. In the present study we compared three methods to measure FRC. DESIGN:The bias flow nitrogen washout techn...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-003-2028-0

    authors： Schibler A,Hammer J,Isler R,Buess C,Newth CJ

    更新日期：2004-01-01 00:00:00

  • The use of etomidate in the management of severe head injury.

    abstract：:The effects of continuous and supplementary bolus dose administration of etomidate have been investigated in ten artificially ventilated patients in traumatic coma. Continuous infusion of etomidate (5-25 micrograms/kg/min) proved to be a practical and safe means of sedating these patients and appeared to control moder...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01692549

    authors： Prior JG,Hinds CJ,Williams J,Prior PF

    更新日期：1983-01-01 00:00:00

  • Adverse cardiac events during catecholamine vasopressor therapy: a prospective observational study.

    abstract：PURPOSE:To determine the incidence of and risk factors for adverse cardiac events during catecholamine vasopressor therapy in surgical intensive care unit patients with cardiovascular failure. METHODS:The occurrence of any of seven predefined adverse cardiac events (prolonged elevated heart rate, tachyarrhythmia, myoc...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2531-2

    authors： Schmittinger CA,Torgersen C,Luckner G,Schröder DC,Lorenz I,Dünser MW

    更新日期：2012-06-01 00:00:00

  • Diagnosis of bacterial infection in the ICU: general principles.

    abstract：:Diagnosis and treatment of infection is a common procedure in the clinical management of patients in the ICU. Infection in the ICU is an important area for study, but requires well-defined and proven diagnostic criteria. The diagnosis of infection, like any diagnosis, is based on probability, and diagnostic criteria a...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/BF01713977

    authors： Langer M,Pifferi S,Peta M

    更新日期：1994-11-01 00:00:00

  • Transnasal puncture based on echographic sinusitis evidence in mechanically ventilated patients with suspicion of nosocomial maxillary sinusitis.

    abstract：OBJECTIVE:The aim of this prospective study was to evaluate the value of sinus echography results to directly indicate a transnasal puncture in intubated patients with suspicion of nosocomial maxillary sinusitis. DESIGN:prospective clinical investigation. SETTING:medical intensive care unit. PATIENTS:sixty patients ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-006-0152-3

    authors： Vargas F,Bui HN,Boyer A,Bébear CM,Lacher-Fougére S,De-Barbeyrac BM,Salmi LR,Traissac L,Gbikpi-Benissan G,Gruson D,Hilbert G

    更新日期：2006-06-01 00:00:00

  • The effect of neuromuscular blockade on oxygen consumption in sedated and mechanically ventilated pediatric patients after cardiac surgery.

    abstract：OBJECTIVE:To measure the effect of intense neuromuscular blockade (NMB) on oxygen consumption (VO(2)) in deeply sedated and mechanically ventilated children on the first day after complex congenital cardiac surgery. DESIGN:Prospective clinical interventional study. SETTING:Pediatric intensive care unit of an universi...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-008-1252-z

    authors： Lemson J,Driessen JJ,van der Hoeven JG

    更新日期：2008-12-01 00:00:00