Adrenal crisis presenting as hypoglycemic coma.

Abstract:

:An 18-month-old male infant presented with hypoglycemic coma and clinical signs of bronchopneumonia. He was suspected of suffering from septic shock. The patient progressed to irreversible multiple organ failure before the diagnosis of adrenal crisis was established. Plasma levels of ACTH and cortisol remained undetectable. Renin and aldosterone were normal. An autopsy failed to demonstrate any adrenal gland cortical tissue. Immunohistochemical staining demonstrated the presence of all pituitary hormones except ACTH, establishing the diagnosis of isolated ACTH deficiency. Intensive care clinicians should consider adrenal crisis in non-diabetic children with hypoglycemia and rapid circulatory deterioration.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Fischer JE,Stallmach T,Fanconi S

doi

10.1007/s001340050021

keywords:

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

105-8

issue

1

eissn

0342-4642

issn

1432-1238

pii

00260105.134

journal_volume

26

pub_type

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