Clostridium difficile infection as a cause of severe sepsis.

abstract：:We evaluated the effect of a cimetidine continuous infusion (2 g in 24 h) on the intragastric pH of 16 critically ill patients (11 men, 5 women, mean age 45 years). During the 24 h pre-trial period and the subsequent 24 h cimetidine infusion, an intragastric combined electrode was placed in the fundus and the pH recor...

journal_title：Intensive care medicine

authors： Tomé G,Fiasse R,Reynaert M,Mahieu P,Hanssens F

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To investigate the correlation between microalbuminuria and extravascular lung water in patients in septic shock who require mechanical ventilation for severe respiratory failure. DESIGN AND SETTING:Prospective, observational, clinical study in the 20-bed intensive care unit of a university hospital. PATIEN...

journal_title：Intensive care medicine

authors： Molnár Z,Szakmány T,Heigl P

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:Atracurium besylate and laudanosine cause excitement and seizures when introduced into the central nervous system of laboratory animals. We examined the modulation of lipid-protein interaction in the lipid environment of rat brain synaptosomal plasma membrane (SPM)-bound enzymes as a possible mechanism leadin...

journal_title：Intensive care medicine

authors： Kamper EF,Siafaka J,Stavridis J

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:Growth hormone (GH) given to reverse muscle catabolism in critical illness increased mortality, illustrating the need for better understanding of the pathophysiology of the GH axis. We describe the relationship between changes in plasma insulin-like growth factor-I (IGF-I) and growth hormone-binding protein (...

journal_title：Intensive care medicine

authors： O'Leary MJ,Quinton N,Ferguson CN,Preedy VR,Ross RJ,Hinds CJ

更新日期：2000-10-01 00:00:00

abstract：:A case of brainstem encephalitis complicated by torsade de pointes is described. The possible occurrence of ventricular arrhythmias may contribute to the mortality in this condition. We recommend the admission of patients with brainstem encephalitis to an intensive care unit, for a period of electrocardiographic monit...

journal_title：Intensive care medicine

authors： De Keyser J,De Boel S,Ceulemans L,Ebinger G

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:To evaluate trends in mortality and related factors among trauma patients who developed acute respiratory distress syndrome (ARDS). STUDY:Observational study based on data prospectively gathered in computerized trauma registry. SETTING:Trauma intensive care unit (ICU) of 48 beds in level I trauma center. P...

journal_title：Intensive care medicine

authors： Navarrete-Navarro P,Rodriguez A,Reynolds N,West R,Habashi N,Rivera R,Chiu WC,Scalea T

更新日期：2001-07-01 00:00:00

abstract：:During a 3-year period, a clinical diagnosis of invasive candidosis was made in 8 out of 2054 consecutive surgical intensive care unit (ICU) patients. These patients were retrospectively matched with 16 control patients who underwent similar surgical procedures and had a similar clinical course except for negative Can...

journal_title：Intensive care medicine

authors： Lepper PM,Wiedeck H,Geldner G,Essig A,Trautmann M

更新日期：2001-05-01 00:00:00

abstract：PURPOSE:We assessed outcomes in brain-injured patients after implementation of a multi-faceted approach to reduce respiratory complications in intensive care units. METHODS:Prospective nationwide before-after trial. Consecutive adults with acute brain injury requiring mechanical ventilation for ≥24 h in 20 French inte...

journal_title：Intensive care medicine

authors： Asehnoune K,Mrozek S,Perrigault PF,Seguin P,Dahyot-Fizelier C,Lasocki S,Pujol A,Martin M,Chabanne R,Muller L,Hanouz JL,Hammad E,Rozec B,Kerforne T,Ichai C,Cinotti R,Geeraerts T,Elaroussi D,Pelosi P,Jaber S,Dalicha

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to explore trends and changes in sedation practices for mechanically ventilated patients in Danish intensive care units (ICUs) and to compare sedation practices in 1997 and 2003. DESIGN:The study was a follow-up survey with a descriptive and comparative cross-sectional multicenter de...

journal_title：Intensive care medicine

authors： Egerod I,Christensen BV,Johansen L

更新日期：2006-01-01 00:00:00

abstract：:Neuromuscular blocking agents (NMBAs) inhibit patient-initiated active breath and the risk of high tidal volumes and consequent high transpulmonary pressure swings, and minimize patient/ ventilator asynchrony in acute respiratory distress syndrome (ARDS). Minimization of volutrauma and ventilator-induced lung injury (...

journal_title：Intensive care medicine

authors： Hraiech S,Yoshida T,Annane D,Duggal A,Fanelli V,Gacouin A,Heunks L,Jaber S,Sottile PD,Papazian L

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:To measure the extent of dilution of helium-oxygen (heliox) by room air when given via high concentration reservoir mask to spontaneously breathing subjects. Substantial dilution of heliox by room air under these circumstances might alter its physical properties sufficiently to negate any potential clinical ...

journal_title：Intensive care medicine

authors： Standley TD,Smith HL,Brennan LJ,Wilkins IA,Bradley PG,Barrera Groba C,Davey AJ,Menon DK,Wheeler DW

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To identify and reduce medication-prescribing errors by introducing systematic physician education and post-cardiac surgery admission prescription forms. DESIGN:Errors were defined as: incomplete prescriptions; potential adverse drug events (ADEs), i.e. either intercepted or non-intercepted incorrect prescri...

journal_title：Intensive care medicine

authors： Burmester MK,Dionne R,Thiagarajan RR,Laussen PC

更新日期：2008-06-01 00:00:00

abstract：:The use of induced hypertension in head injury patients is controversial. We present the case of a 19-year-old man admitted with severe head trauma after a road accident and describe the beneficial effects that increasing arterial blood pressure had on the cerebral perfusion pressure, cerebral blood flow and jugular b...

journal_title：Intensive care medicine

authors： Ferring M,Berré J,Vincent JL

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:To implement delirium monitoring, test reliability, and monitor compliance of performing the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) in trauma patients. DESIGN AND SETTING:Prospective, observational study in a level 1 trauma unit of a tertiary care, university-based medical center. ...

journal_title：Intensive care medicine

authors： Soja SL,Pandharipande PP,Fleming SB,Cotton BA,Miller LR,Weaver SG,Lee BT,Ely EW

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:Fibroproliferation markers like procollagen I predict mortality in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). We sought to determine whether bronchoalveolar lavage fluid (BALF) from patients with lung injury contained mediators that would activate procollagen I promo...

journal_title：Intensive care medicine

authors： Budinger GR,Chandel NS,Donnelly HK,Eisenbart J,Oberoi M,Jain M

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To assess the effects of intravenous fish oil fat emulsion on the metabolic alterations induced by lipopolysaccharide (LPS) challenge in healthy volunteers. DESIGN:Two groups of eight healthy subjects were randomized to receive either two pharmacological doses of intravenous FO fat emulsion or no treatment. ...

journal_title：Intensive care medicine

authors： Pluess TT,Hayoz D,Berger MM,Tappy L,Revelly JP,Michaeli B,Carpentier YA,Chioléro RL

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To examine the usefulness of preload indices obtained by transoesophageal echocardiography (TOE) for estimating stroke volume at various levels of cardiac index. DESIGN:Prospective clinical study. SETTING:Intensive care unit with surgical patients. PATIENTS:16 ventilated patients monitored via Swan-Ganz ca...

journal_title：Intensive care medicine

authors： Greim CA,Roewer N,Apfel C,Laux G,Schulte am Esch J

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To determine the reliability of estimating arterial CO(2) pressure (PaCO(2)) using a recently introduced transcutaneous CO(2) pressure (PtcCO(2)) monitor in severe obese patients. DESIGN:Observational and interventional study. SETTING:District hospital with respiratory ward and bariatric surgery unit. PATI...

journal_title：Intensive care medicine

authors： Maniscalco M,Zedda A,Faraone S,Carratù P,Sofia M

更新日期：2008-07-01 00:00:00

abstract：UNLABELLED:Admission of cancer patients with serious medical complications to the ICU remains controversial primarily because of the high short-term mortality rates in these patients. However, the cancer patient population is heterogeneous regarding age, underlying conditions, and curability of their disease, suggestin...

journal_title：Intensive care medicine

authors： Azoulay E,Moreau D,Alberti C,Leleu G,Adrie C,Barboteu M,Cottu P,Levy V,Le Gall JR,Schlemmer B

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVES:To determine the effects of an intravenous bolus dose of a vasopressin analogue, terlipressin (1 mg), on systemic haemodynamic parameters and gastric mucosal perfusion (GMP) in patients with catecholamine-treated septic shock using a gastric tonometry and laser-Doppler flowmetry technique. DESIGN:Prospectiv...

journal_title：Intensive care medicine

authors： Morelli A,Rocco M,Conti G,Orecchioni A,De Gaetano A,Cortese G,Coluzzi F,Vernaglione E,Pelaia P,Pietropaoli P

更新日期：2004-04-01 00:00:00

abstract：PURPOSE:To provide recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza pandemic or mass disaster with a specific focus on essential equipment, pharmaceuticals and supplies. METHODS:Based on a literature review and expert opinion, a Delphi process was use...

journal_title：Intensive care medicine

authors： Sprung CL,Kesecioglu J,European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mass disaster.

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To compare outcome prediction using the Multiple Organ Dysfunction Score (MODS) and the Sequential Organ Failure Assessment (SOFA), two of the systems most commonly used to evaluate organ dysfunction in the intensive care unit (ICU). DESIGN:Prospective, observational study. SETTING:Thirty-one-bed, universit...

journal_title：Intensive care medicine

authors： Peres Bota D,Melot C,Lopes Ferreira F,Nguyen Ba V,Vincent JL

更新日期：2002-11-01 00:00:00

abstract：:The reliability of cardiac output estimation by thermodilution during artificial ventilation was studied in anesthetized pigs at the right side of the heart. The estimates exhibited a cyclic modulation related to the ventilation. The amplitude of the modulation was independent of the level of positive end-expiratory p...

journal_title：Intensive care medicine

authors： Jansen JR,Versprille A

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:To determine whether, during mechanical ventilation, an optimal positive end-expiratory pressure (PEEP) can be identified by measurement of regional tidal volume and compliance [V (T(reg)), C (RS(reg))]. METHODS:Sixteen anaesthetized intubated neonatal piglets underwent a stepwise vital capacity manoeuvre perf...

journal_title：Intensive care medicine

authors： Dargaville PA,Rimensberger PC,Frerichs I

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:We examined in rabbits the effects of more than 48 h of mechanical ventilation on the contractile properties and fiber type adaptations of the respiratory muscles. DESIGN AND SETTING:Experimental prospective study in a university laboratory. ANIMALS AND INTERVENTIONS:Nineteen rabbits were randomly allocated...

journal_title：Intensive care medicine

authors： Capdevila X,Lopez S,Bernard N,Rabischong E,Ramonatxo M,Martinazzo G,Prefaut C

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Based on limited data, Candida sp. isolates from bronchoalveolar lavage (BAL) cultures in immunocompetent patients are thought to be contaminants rather than pathogens. The objective of this study was to determine the clinical significance of Candida sp. isolated from BAL cultures in critically ill trauma pat...

journal_title：Intensive care medicine

authors： Wood GC,Mueller EW,Croce MA,Boucher BA,Fabian TC

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:Inhalation of high concentrations of nitric oxide (NO) has been shown to improve gas exchange and to reduce pulmonary vascular resistance in individuals with ischemia-reperfusion injury following orthotopic lung transplantation. We assessed the cardiopulmonary effects of low doses of NO in early allograft dys...

journal_title：Intensive care medicine

authors： Kemming GI,Merkel MJ,Schallerer A,Habler OP,Kleen MS,Haller M,Briegel J,Vogelmeier C,Fürst H,Reichart B,Zwissler B

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To investigate the regional partial pressure of oxygen (PO2) and partial pressure of carbon dioxide (PCO2) of the perfluorocarbon liquid (PpfcO2, PpfcCO2) during partial liquid ventilation (PLV). DESIGN:Prospective, controlled study. SETTING:A research laboratory at a university medical center. SUBJECTS:Th...

journal_title：Intensive care medicine

authors： Uchida T,Yokoyama K,Nakazawa K,Makita K

更新日期：2001-01-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Stefani A,Ruggiero C,Aramini B,Scamporlino A

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To describe the clinical course of quinine-induced disseminated intravascular coagulation (DIC) and review all previous cases reported in the medical literature. DESIGN:Case report/literature review. SETTING:University teaching hospital medical ICU. PATIENTS:One patient in whom thrombocytopenia, coagulopat...

journal_title：Intensive care medicine

authors： Knower MT,Bowton DL,Owen J,Dunagan DP

更新日期：2003-06-01 00:00:00