Correction: Female genital schistosomiasis and HIV/AIDS: Reversing the neglect of girls and women.


:[This corrects the article DOI: 10.1371/journal.pntd.0007025.].


PLoS Negl Trop Dis


Hotez PJ,Harrison W,Fenwick A,Bustinduy AL,Ducker C,Mbabazi PS,Engels D,Kjetland EF




Has Abstract


2020-09-01 00:00:00














  • Capture-based enrichment of Theileria parva DNA enables full genome assembly of first buffalo-derived strain and reveals exceptional intra-specific genetic diversity.

    abstract::Theileria parva is an economically important, intracellular, tick-transmitted parasite of cattle. A live vaccine against the parasite is effective against challenge from cattle-transmissible T. parva but not against genotypes originating from the African Cape buffalo, a major wildlife reservoir, prompting the need to ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Palmateer NC,Tretina K,Orvis J,Ifeonu OO,Crabtree J,Drabék E,Pelle R,Awino E,Gotia HT,Munro JB,Tallon L,Morrison WI,Daubenberger CA,Nene V,Knowles DP,Bishop RP,Silva JC

    更新日期:2020-10-29 00:00:00

  • Performance Testing of PCR Assay in Blood Samples for the Diagnosis of Toxoplasmic Encephalitis in AIDS Patients from the French Departments of America and Genetic Diversity of Toxoplasma gondii: A Prospective and Multicentric Study.

    abstract:BACKGROUND:Toxoplasmic encephalitis in patients with AIDS is a life-threatening disease mostly due to reactivation of Toxoplasma gondii cysts in the brain. The main objective of this study was to evaluate the performance of real-time PCR assay in peripheral blood samples for the diagnosis of toxoplasmic encephalitis in...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章,多中心研究


    authors: Ajzenberg D,Lamaury I,Demar M,Vautrin C,Cabié A,Simon S,Nicolas M,Desbois-Nogard N,Boukhari R,Riahi H,Dardé ML,Massip P,Dupon M,Preux PM,Labrunie A,Boncoeur MP

    更新日期:2016-06-29 00:00:00

  • Complexities and Perplexities: A Critical Appraisal of the Evidence for Soil-Transmitted Helminth Infection-Related Morbidity.

    abstract:BACKGROUND:Soil-transmitted helminths (STH) have acute and chronic manifestations, and can result in lifetime morbidity. Disease burden is difficult to quantify, yet quantitative evidence is required to justify large-scale deworming programmes. A recent Cochrane systematic review, which influences Global Burden of Dise...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章,meta分析,评审


    authors: Campbell SJ,Nery SV,Doi SA,Gray DJ,Soares Magalhães RJ,McCarthy JS,Traub RJ,Andrews RM,Clements AC

    更新日期:2016-05-19 00:00:00

  • The public health benefit and burden of mass drug administration programs in Vietnamese schoolchildren: Impact of mebendazole.

    abstract:BACKGROUND:Mass anthelmintic drug administration is recommended in developing countries to address infection by soil-transmitted helminthiases (STH). We quantified the public health benefit of treatment with mebendazole in eight million Vietnamese children aged 5-14 years from 2006 to 2011. This was compared to the env...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Debaveye S,Gonzalez Torres CV,De Smedt D,Heirman B,Kavanagh S,Dewulf J

    更新日期:2018-11-12 00:00:00

  • Vector competence of Aedes aegypti, Culex tarsalis, and Culex quinquefasciatus from California for Zika virus.

    abstract::Zika virus (ZIKV) has emerged since 2013 as a significant global human health threat following outbreaks in the Pacific Islands and rapid spread throughout South and Central America. Severe congenital and neurological sequelae have been linked to ZIKV infections. Assessing the ability of common mosquito species to tra...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Main BJ,Nicholson J,Winokur OC,Steiner C,Riemersma KK,Stuart J,Takeshita R,Krasnec M,Barker CM,Coffey LL

    更新日期:2018-06-21 00:00:00

  • Identification of clinically approved small molecules that inhibit growth and affect transcript levels of developmentally regulated genes in the African trypanosome.

    abstract::Trypanosoma brucei are unicellular parasites endemic to Sub-Saharan Africa that cause fatal disease in humans and animals. Infection with these parasites is caused by the bite of the tsetse fly vector, and parasites living extracellularly in the blood of infected animals evade the host immune system through antigenic ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Walsh ME,Naudzius EM,Diaz SJ,Wismar TW,Martchenko Shilman M,Schulz D

    更新日期:2020-03-13 00:00:00

  • Allergies and diabetes as risk factors for dengue hemorrhagic fever: results of a case control study.

    abstract:BACKGROUND:The physiopathology of dengue hemorrhagic fever (DHF), a severe form of Dengue Fever, is poorly understood. We are unable to identify patients likely to progress to DHF for closer monitoring and early intervention during epidemics, so most cases are sent home. This study explored whether patients with select...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Figueiredo MA,Rodrigues LC,Barreto ML,Lima JW,Costa MC,Morato V,Blanton R,Vasconcelos PF,Nunes MR,Teixeira MG

    更新日期:2010-06-01 00:00:00

  • Geographic variation in access to dog-bite care in Pakistan and risk of dog-bite exposure in Karachi: prospective surveillance using a low-cost mobile phone system.

    abstract:BACKGROUND:Dog-bites and rabies are under-reported in developing countries such as Pakistan and there is a poor understanding of the disease burden. We prospectively collected data utilizing mobile phones for dog-bite and rabies surveillance across nine emergency rooms (ER) in Pakistan, recording patient health-seeking...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Zaidi SM,Labrique AB,Khowaja S,Lotia-Farrukh I,Irani J,Salahuddin N,Khan AJ

    更新日期:2013-12-12 00:00:00

  • Quantifying the burden of rhodesiense sleeping sickness in Urambo District, Tanzania.

    abstract:BACKGROUND:Human African trypanosomiasis is a severely neglected vector-borne disease that is always fatal if untreated. In Tanzania it is highly focalised and of major socio-economic and public health importance in affected communities. OBJECTIVES:This study aimed to estimate the public health burden of rhodesiense H...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Matemba LE,Fèvre EM,Kibona SN,Picozzi K,Cleaveland S,Shaw AP,Welburn SC

    更新日期:2010-11-02 00:00:00

  • A non mouse-adapted dengue virus strain as a new model of severe dengue infection in AG129 mice.

    abstract::The spread of dengue (DEN) worldwide combined with an increased severity of the DEN-associated clinical outcomes have made this mosquito-borne virus of great global public health importance. Progress in understanding DEN pathogenesis and in developing effective treatments has been hampered by the lack of a suitable sm...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Tan GK,Ng JK,Trasti SL,Schul W,Yip G,Alonso S

    更新日期:2010-04-27 00:00:00

  • Infrared fluorescent imaging as a potent tool for in vitro, ex vivo and in vivo models of visceral leishmaniasis.

    abstract:BACKGROUND:Visceral leishmaniasis (VL) is hypoendemic in the Mediterranean region, where it is caused by the protozoan Leishmania infantum. An effective vaccine for humans is not yet available and the severe side-effects of the drugs in clinical use, linked to the parenteral administration route of most of them, are si...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Calvo-Álvarez E,Stamatakis K,Punzón C,Álvarez-Velilla R,Tejería A,Escudero-Martínez JM,Pérez-Pertejo Y,Fresno M,Balaña-Fouce R,Reguera RM

    更新日期:2015-03-31 00:00:00

  • Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: Species typing and flow of travelers and migrants with leishmaniasis.

    abstract:BACKGROUND:We identified the species of Leishmania isolated from traveling and migrant patients attended in a reference center from 2000 to 2015, we performed the georeferencing of these species in Rio de Janeiro (RJ) state and we had knowledge about the human flows between the likely location of infection (LLI) and pl...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Miranda LFC,Pacheco RDS,Pimentel MIF,Salgueiro MM,da Silva AF,de Mello CX,Barros JHDS,Valete-Rosalino CM,Madeira MF,Xavier SCDC,Schubach AO

    更新日期:2019-11-15 00:00:00

  • Suppression of a Field Population of Aedes aegypti in Brazil by Sustained Release of Transgenic Male Mosquitoes.

    abstract::The increasing burden of dengue, and the relative failure of traditional vector control programs highlight the need to develop new control methods. SIT using self-limiting genetic technology is one such promising method. A self-limiting strain of Aedes aegypti, OX513A, has already reached the stage of field evaluation...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Carvalho DO,McKemey AR,Garziera L,Lacroix R,Donnelly CA,Alphey L,Malavasi A,Capurro ML

    更新日期:2015-07-02 00:00:00

  • A cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus infection in China, 1996: A retrospective serological study.

    abstract:BACKGROUND:A cluster of eleven patients, including eight family members and three healthcare workers with fever and thrombocytopenia occurred in Yixing County, Jiangsu Province, China, from October to November 1996. However, the initial investigation failed to identify its etiology. Severe fever with thrombocytopenia s...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Hu J,Shi C,Li Z,Guo X,Qian Y,Tan W,Li X,Qi X,Su X,Zhou M,Wang H,Jiao Y,Bao C

    更新日期:2018-06-25 00:00:00

  • Transcriptomes of Trypanosoma brucei rhodesiense from sleeping sickness patients, rodents and culture: Effects of strain, growth conditions and RNA preparation methods.

    abstract::All of our current knowledge of African trypanosome metabolism is based on results from trypanosomes grown in culture or in rodents. Drugs against sleeping sickness must however treat trypanosomes in humans. We here compare the transcriptomes of Trypanosoma brucei rhodesiense from the blood and cerebrospinal fluid of ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Mulindwa J,Leiss K,Ibberson D,Kamanyi Marucha K,Helbig C,Melo do Nascimento L,Silvester E,Matthews K,Matovu E,Enyaru J,Clayton C

    更新日期:2018-02-23 00:00:00

  • Congenital toxoplasmosis in Austria: Prenatal screening for prevention is cost-saving.

    abstract:BACKGROUND:Primary infection of Toxoplasma gondii during pregnancy can be transmitted to the unborn child and may have serious consequences, including retinochoroiditis, hydrocephaly, cerebral calcifications, encephalitis, splenomegaly, hearing loss, blindness, and death. Austria, a country with moderate seroprevalence...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Prusa AR,Kasper DC,Sawers L,Walter E,Hayde M,Stillwaggon E

    更新日期:2017-07-10 00:00:00

  • "Omic" investigations of protozoa and worms for a deeper understanding of the human gut "parasitome".

    abstract::The human gut has been continuously exposed to a broad spectrum of intestinal organisms, including viruses, bacteria, fungi, and parasites (protozoa and worms), over millions of years of coevolution, and plays a central role in human health. The modern lifestyles of Western countries, such as the adoption of highly hy...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章,评审


    authors: Marzano V,Mancinelli L,Bracaglia G,Del Chierico F,Vernocchi P,Di Girolamo F,Garrone S,Tchidjou Kuekou H,D'Argenio P,Dallapiccola B,Urbani A,Putignani L

    更新日期:2017-11-02 00:00:00

  • Identification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic Trypanosomatids.

    abstract:BACKGROUND:The search for novel chemical entities targeting essential and parasite-specific pathways is considered a priority for neglected diseases such as trypanosomiasis and leishmaniasis. The thiol-dependent redox metabolism of trypanosomatids relies on bis-glutathionylspermidine [trypanothione, T(SH)2], a low mole...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Benítez D,Medeiros A,Fiestas L,Panozzo-Zenere EA,Maiwald F,Prousis KC,Roussaki M,Calogeropoulou T,Detsi A,Jaeger T,Šarlauskas J,Peterlin Mašič L,Kunick C,Labadie GR,Flohé L,Comini MA

    更新日期:2016-04-12 00:00:00

  • Wide range of G6PD activities found among ethnic groups of the Chittagong Hill Tracts, Bangladesh.

    abstract::The proportion of Plasmodium vivax malaria among all malarias is increasing worldwide. Treatment with 8-aminoquinolines remain the only radical cure. However, 8-aminoquinolines can cause severe hemolysis in glucose-6-phosphate dehydrogenase (G6PD) deficient patients. The population of the multi-ethnic Chittagong Hill ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Ley B,Kibria MG,Khan WA,Auburn S,Phru CS,Jahan N,Johora FT,Thriemer K,Ami JQ,Hossain MS,Price RN,Koepfli C,Alam MS

    更新日期:2020-09-14 00:00:00

  • Prevalence and Transmission of Trypanosoma cruzi in People of Rural Communities of the High Jungle of Northern Peru.

    abstract:BACKGROUND:Vector-borne transmission of Trypanosoma cruzi is seen exclusively in the Americas where an estimated 8 million people are infected with the parasite. Significant research in southern Peru has been conducted to understand T. cruzi infection and vector control, however, much less is known about the burden of ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Alroy KA,Huang C,Gilman RH,Quispe-Machaca VR,Marks MA,Ancca-Juarez J,Hillyard M,Verastegui M,Sanchez G,Cabrera L,Vidal E,Billig EM,Cama VA,Náquira C,Bern C,Levy MZ,Working Group on Chagas Disease in Peru.

    更新日期:2015-05-22 00:00:00

  • Molecular identification and antifungal susceptibility profiles of clinical strains of Fonsecaea spp. isolated from patients with chromoblastomycosis in Rio de Janeiro, Brazil.

    abstract:BACKGROUND:Chromoblastomycosis (CBM) is a difficult-to-treat chronic subcutaneous mycosis. In Brazil, the main agent of this disease is Fonsecaea pedrosoi, which is phenotypically very similar to other Fonsecaea species, differing only genetically. The correct species identification is relevant since different species ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Coelho RA,Brito-Santos F,Figueiredo-Carvalho MHG,Silva JVDS,Gutierrez-Galhardo MC,do Valle ACF,Zancopé-Oliveira RM,Trilles L,Meyer W,Freitas DFS,Almeida-Paes R

    更新日期:2018-07-26 00:00:00

  • Bacterial diversity in oral samples of children in niger with acute noma, acute necrotizing gingivitis, and healthy controls.

    abstract:BACKGROUND:Noma is a gangrenous disease that leads to severe disfigurement of the face with high morbidity and mortality, but its etiology remains unknown. Young children in developing countries are almost exclusively affected. The purpose of the study was to record and compare bacterial diversity in oral samples from ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Bolivar I,Whiteson K,Stadelmann B,Baratti-Mayer D,Gizard Y,Mombelli A,Pittet D,Schrenzel J,Geneva Study Group on Noma (GESNOMA).

    更新日期:2012-01-01 00:00:00

  • Post-kala-azar dermal leishmaniasis in Nepal: a retrospective cohort study (2000-2010).

    abstract:INTRODUCTION:Post-kala-azar dermal leishmaniasis (PKDL) is a cutaneous complication appearing after treatment of visceral leishmaniasis, and PKDL patients are considered infectious to sand flies and may therefore play a role in the transmission of VL. We estimated the risk and risk factors of PKDL in patients with past...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Uranw S,Ostyn B,Rijal A,Devkota S,Khanal B,Menten J,Boelaert M,Rijal S

    更新日期:2011-12-01 00:00:00

  • Thalidomide in the treatment of erythema nodosum leprosum (ENL) in an outpatient setting: A five-year retrospective analysis from a leprosy referral centre in India.

    abstract::Erythema nodosum leprosum (ENL), or type 2 lepra reaction, is a multi-system immune-mediated complication in patients with multibacillary leprosy, frequently associated with chronicity and recurrences. Management of ENL requires high doses of oral corticosteroids, which may not be universally effective and pose seriou...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Upputuri B,Pallapati MS,Tarwater P,Srikantam A

    更新日期:2020-10-09 00:00:00

  • Tsetse GmmSRPN10 has anti-complement activity and is important for successful establishment of trypanosome infections in the fly midgut.

    abstract::The complement cascade in mammalian blood can damage the alimentary tract of haematophagous arthropods. As such, these animals have evolved their own repertoire of complement-inactivating factors, which are inadvertently exploited by blood-borne pathogens to escape complement lysis. Unlike the bloodstream stages, the ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Ooi CP,Haines LR,Southern DM,Lehane MJ,Acosta-Serrano A

    更新日期:2015-01-08 00:00:00

  • Identifying Patient Perceived Barriers to Trichiasis Surgery in Kongwa District, Tanzania.

    abstract:BACKGROUND:Trachomatous trichiasis (TT), inturned eyelashes from repeated infection with Chlamydia trachomatis, is the leading infectious cause of blindness in the world. Though surgery will correct entropion caused by trachoma, uptake of TT surgery remains low. In this case-control study, we identify barriers that pre...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Bickley RJ,Mkocha H,Munoz B,West S

    更新日期:2017-01-04 00:00:00

  • Vaccination with a chikungunya virus-like particle vaccine exacerbates disease in aged mice.

    abstract:INTRODUCTION:Chikungunya virus (CHIKV) is a re-emerging pathogen responsible for causing outbreaks of febrile disease accompanied with debilitating joint pain. Symptoms typically persist for two weeks, but more severe and chronic chikungunya illnesses have been reported, especially in the elderly. Currently, there are ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Arévalo MT,Huang Y,Jones CA,Ross TM

    更新日期:2019-04-26 00:00:00

  • Circulation of Japanese encephalitis virus in pigs and mosquito vectors within Can Tho city, Vietnam.

    abstract::Japanese encephalitis virus (JEV) is a mosquito-borne, zoonotic flavivirus causing encephalitis in humans and reproductive disorder in pigs. JEV is present in large parts of Asia, where urbanization is high. Households within and outside Can Tho city, South Vietnam, were selected to monitor circulation of JEV. A neste...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Lindahl JF,Ståhl K,Chirico J,Boqvist S,Thu HT,Magnusson U

    更新日期:2013-04-04 00:00:00

  • Nelfinavir, an HIV-1 protease inhibitor, induces oxidative stress-mediated, caspase-independent apoptosis in Leishmania amastigotes.

    abstract:BACKGROUND:Visceral leishmaniasis has now emerged as an important opportunistic disease in patients coinfected with human immunodeficiency virus type-1 (HIV-1). Although the effectiveness of HIV-1 protease inhibitors, such as nelfinavir, in antiretroviral therapies is well documented, little is known of the impact of t...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Kumar P,Lodge R,Trudel N,Ouellet M,Ouellette M,Tremblay MJ

    更新日期:2010-03-30 00:00:00

  • Dramatic changes in gene expression in different forms of Crithidia fasciculata reveal potential mechanisms for insect-specific adhesion in kinetoplastid parasites.

    abstract::Kinetoplastids are a group of parasites that includes several medically-important species. These human-infective species are transmitted by insect vectors in which the parasites undergo specific developmental transformations. For each species, this includes a stage in which parasites adhere to insect tissue via a hemi...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Filosa JN,Berry CT,Ruthel G,Beverley SM,Warren WC,Tomlinson C,Myler PJ,Dudkin EA,Povelones ML,Povelones M

    更新日期:2019-07-29 00:00:00