Rabies Risk: Difficulties Encountered during Management of Grouped Cases of Bat Bites in 2 Isolated Villages in French Guiana.

abstract：:A cross sectional serological survey of arboviral infections in humans was conducted on the three islands of the Union of Comoros, Indian Ocean, in order to test a previously suggested contrasted exposure of the three neighboring islands to arthropod-borne epidemics. Four hundred human sera were collected on Ngazidja ...

journal_title：PLoS neglected tropical diseases

authors： Dellagi K,Salez N,Maquart M,Larrieu S,Yssouf A,Silaï R,Leparc-Goffart I,Tortosa P,de Lamballerie X

更新日期：2016-12-15 00:00:00

abstract：BACKGROUND:Most commonly used malaria diagnostic tests, including microscopy and antigen-detecting rapid tests, cannot reliably detect low-density infections which are frequent in low transmission settings. Molecular methods such as polymerase chain reaction (PCR) are highly sensitive but remain too laborious for field...

journal_title：PLoS neglected tropical diseases

authors： Vallejo AF,Martínez NL,González IJ,Arévalo-Herrera M,Herrera S

更新日期：2015-01-08 00:00:00

abstract：:The causative agent of cholera, Vibrio cholerae, regulates its diverse virulence factors to thrive in the human small intestine and environmental reservoirs. Among this pathogen's arsenal of virulence factors is the tightly regulated type VI secretion system (T6SS). This system acts as an inverted bacteriophage to inj...

journal_title：PLoS neglected tropical diseases

authors： Bachmann V,Kostiuk B,Unterweger D,Diaz-Satizabal L,Ogg S,Pukatzki S

更新日期：2015-08-28 00:00:00

abstract：:We evaluated the protection conferred by a first documented visit for clinical care of typhoid fever against recurrent typhoid fever prompting a visit. This study takes advantage of multi-year follow-up of a population with endemic typhoid participating in a cluster-randomized control trial of Vi capsular polysacchari...

journal_title：PLoS neglected tropical diseases

authors： Im J,Islam MT,Kim DR,Ahmmed F,Chon Y,Zaman K,Khan AI,Ali M,Sur D,Kanungo S,Dutta S,Bhattacharya SK,Dougan G,Holt KE,Marks F,Kim JH,Qadri F,Clemens JD

更新日期：2020-08-17 00:00:00

abstract：BACKGROUND:Bartonella bacilliformis is the etiological agent of Carrion's disease, a neglected tropical poverty-linked illness. This infection is endemic of Andean regions and it is estimated that approximately 1.7 million of South Americans are at risk. This bacterium is a fastidious slow growing microorganism, which ...

journal_title：PLoS neglected tropical diseases

authors： Pons MJ,Silva-Caso W,Del Valle-Mendoza J,Ruiz J

更新日期：2016-01-29 00:00:00

abstract：BACKGROUND:A relatively simple life history allows us to derive an expression for the extinction probability of populations of tsetse, vectors of African sleeping sickness. We present the uncertainty and sensitivity analysis of the extinction probability, to offer key insights into factors affecting the control or erad...

journal_title：PLoS neglected tropical diseases

authors： Are EB,Hargrove JW

更新日期：2020-05-11 00:00:00

abstract：BACKGROUND:Lymphatic filariasis (LF) is a so-called neglected tropical disease, currently overshadowed by higher-profile efforts to address malaria, tuberculosis, and HIV/AIDS. Despite recent successes in arresting transmission, some 40 million people who already have the disease have been largely neglected. This study...

journal_title：PLoS neglected tropical diseases

authors： Perera M,Whitehead M,Molyneux D,Weerasooriya M,Gunatilleke G

更新日期：2007-11-21 00:00:00

abstract：BACKGROUND:The objectives of this study were to 1) evaluate the influence of treatment with praziquantel on the inflammatory milieu in maternal, placental, and cord blood, 2) assess the extent to which proinflammatory signatures in placental and cord blood impacts birth outcomes, and 3) evaluate the impact of other hel...

journal_title：PLoS neglected tropical diseases

authors： Abioye AI,McDonald EA,Park S,Joshi A,Kurtis JD,Wu H,Pond-Tor S,Sharma S,Ernerudh J,Baltazar P,Acosta LP,Olveda RM,Tallo V,Friedman JF

更新日期：2019-06-12 00:00:00

abstract：:In mammals subverted as hosts by protozoan parasites, the latter and/or the agonists they release are detected and processed by sensors displayed by many distinct immune cell lineages, in a tissue(s)-dependent context. Focusing on the T lymphocyte lineage, we review our present understanding on its transient or durabl...

journal_title：PLoS neglected tropical diseases

authors： Rodrigues V,Cordeiro-da-Silva A,Laforge M,Ouaissi A,Akharid K,Silvestre R,Estaquier J

更新日期：2014-02-13 00:00:00

abstract：BACKGROUND:Crimean-Congo hemorrhagic fever (CCHF) activity has recently been detected in the Kordufan region of Sudan. Since 2008, several sporadic cases and nosocomial outbreaks associated with high case-fatality have been reported in villages and rural hospitals in the region. PRINCIPAL FINDINGS:In the present study...

journal_title：PLoS neglected tropical diseases

authors： Aradaib IE,Erickson BR,Karsany MS,Khristova ML,Elageb RM,Mohamed ME,Nichol ST

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Molecular diagnostics has become essential in the identification of many infectious and neglected diseases, and the detection of nucleic acids often serves as the gold standard technique for most infectious agents. However, established techniques like polymerase chain reaction (PCR) are time-consuming labora...

journal_title：PLoS neglected tropical diseases

authors： Müller K,Daßen S,Holowachuk S,Zwirglmaier K,Stehr J,Buersgens F,Ullerich L,Stoecker K

更新日期：2021-01-29 00:00:00

abstract：:Diagnosis of a first-time visceral leishmaniasis (VL) infection in Ethiopia is established by use of a rapid diagnostic test (RDT) detecting antibodies against rK39, direct agglutination test (DAT) and microscopy according to the national algorithm. The performance of individual tests and algorithm is variable and dep...

journal_title：PLoS neglected tropical diseases

authors： Kassa M,Abdellati S,Cnops L,Bremer Hinckel BC,Yeshanew A,Hailemichael W,Vogt F,Adriaensen W,Mertens P,Diro E,van Griensven J,Van den Bossche D

更新日期：2020-12-31 00:00:00

abstract：:In the current study, a comprehensive, data driven, mathematical model for cholera transmission in Haiti is presented. Along with the inclusion of short cycle human-to-human transmission and long cycle human-to-environment and environment-to-human transmission, this novel dynamic model incorporates both the reported c...

journal_title：PLoS neglected tropical diseases

authors： Kirpich A,Weppelmann TA,Yang Y,Ali A,Morris JG Jr,Longini IM

更新日期：2015-10-21 00:00:00

abstract：BACKGROUND:Most of the Leishmania genome is reported to be constitutively expressed during the life cycle of the parasite, with a few regulated genes. Inter-species comparative transcriptomics evidenced a low number of species-specific differences related to differentially distributed genes or the differential regulati...

journal_title：PLoS neglected tropical diseases

authors： Adaui V,Castillo D,Zimic M,Gutierrez A,Decuypere S,Vanaerschot M,De Doncker S,Schnorbusch K,Maes I,Van der Auwera G,Maes L,Llanos-Cuentas A,Arevalo J,Dujardin JC

更新日期：2011-05-10 00:00:00

abstract：OBJECTIVE:The aim of the study is to examine the spatiotemporal pattern of Japanese Encephalitis (JE) in mainland China during 2002-2010. Specific objectives of the study were to quantify the temporal variation in incidence of JE cases, to determine if clustering of JE cases exists, to detect high risk spatiotemporal c...

journal_title：PLoS neglected tropical diseases

authors： Wang LY,Zhang WY,Ding F,Hu WB,Soares Magalhaes RJ,Sun HL,Li YX,Zou W,Wang Y,Liu QY,Li SL,Yin WW,Huang LY,Clements AC,Bi P,Li CY

更新日期：2013-06-20 00:00:00

abstract：:Leprosy is a chronic infectious disease that is caused by the obligate intracellular pathogen Mycobacterium leprae (M.leprae), which is the leading cause of all non-traumatic peripheral neuropathies worldwide. Although both myelinating and non-myelinating Schwann cells are infected by M.leprae in patients with leproma...

journal_title：PLoS neglected tropical diseases

authors： Jin SH,An SK,Lee SB

更新日期：2017-06-21 00:00:00

abstract：:Global distribution patterns of Cladophialophora carrionii, agent of human chromoblastomycosis in arid climates of Africa, Asia, Australia, Central-and South-America, were compared with similar data of the vicarious Fonsecaea spp., agents of the disease in tropical rain forests. Population diversities among 73 C. carr...

journal_title：PLoS neglected tropical diseases

authors： Deng S,Tsui CK,Gerrits van den Ende AH,Yang L,Najafzadeh MJ,Badali H,Li R,Hagen F,Meis JF,Sun J,Dolatabadi S,Papierok B,Pan W,de Hoog GS,Liao W

更新日期：2015-10-23 00:00:00

abstract：BACKGROUND:Venom recurrence or persistence in the circulation after antivenom treatment has been documented many times in viper envenoming. However, it has not been associated with clinical recurrence for many snakes, including Russell's viper (Daboia spp.). We compare the recovery of coagulopathy to the recurrence or ...

journal_title：PLoS neglected tropical diseases

authors： Maduwage K,O'Leary MA,Scorgie FE,Shahmy S,Mohamed F,Abeysinghe C,Karunathilake H,Lincz LF,Gnanathasan CA,Isbister GK

更新日期：2014-12-18 00:00:00

abstract：BACKGROUND:Noma is a gangrenous disease that leads to severe disfigurement of the face with high morbidity and mortality, but its etiology remains unknown. Young children in developing countries are almost exclusively affected. The purpose of the study was to record and compare bacterial diversity in oral samples from ...

journal_title：PLoS neglected tropical diseases

authors： Bolivar I,Whiteson K,Stadelmann B,Baratti-Mayer D,Gizard Y,Mombelli A,Pittet D,Schrenzel J,Geneva Study Group on Noma (GESNOMA).

更新日期：2012-01-01 00:00:00

abstract：:Vector control is still our primary intervention for both prevention and mitigation of epidemics of many vector-borne diseases. Efficiently targeting control measures is important since control can involve substantial economic costs. Targeting is not always straightforward, as transmission of vector-borne diseases is ...

journal_title：PLoS neglected tropical diseases

authors： Stone CM,Schwab SR,Fonseca DM,Fefferman NH

更新日期：2019-07-03 00:00:00

abstract：:[This corrects the article DOI: 10.1371/journal.pntd.0004470.]. ...

journal_title：PLoS neglected tropical diseases

authors： Decuypere S,Meehan CJ,Van Puyvelde S,De Block T,Maltha J,Palpouguini L,Tahita M,Tinto H,Jacobs J,Deborggraeve S

更新日期：2017-07-28 00:00:00

abstract：BACKGROUND:Diagnosis of Trypanosoma cruzi infection by direct pathogen detection is complicated by the low parasite burden in subjects persistently infected with this agent of human Chagas disease. Determination of infection status by serological analysis has also been faulty, largely due to the lack of well-characteri...

journal_title：PLoS neglected tropical diseases

authors： Cooley G,Etheridge RD,Boehlke C,Bundy B,Weatherly DB,Minning T,Haney M,Postan M,Laucella S,Tarleton RL

更新日期：2008-10-08 00:00:00

abstract：:In this communication, a case of black grain eumycetoma produced by the fungus C. atrobrunneum is reported. The patient was initially misdiagnosed with M. mycetomatis eumycetoma based on the grains' morphological and cytological features. However, further aerobic culture of the black grains generated a melanised fungu...

journal_title：PLoS neglected tropical diseases

authors： Mhmoud NA,Santona A,Fiamma M,Siddig EE,Deligios M,Bakhiet SM,Rubino S,Fahal AH

更新日期：2019-05-30 00:00:00

abstract：BACKGROUND:Dengue is an important arboviral disease with about 100 million dengue cases per year, of which, ~5% result in severe disease. Clinical differentiation of dengue from other acute febrile illnesses (AFI) is difficult, and diagnostic blood tests are costly. We evaluated the utility of anti-DENV IgM in urine to...

journal_title：PLoS neglected tropical diseases

authors： Caraballo E,Poole-Smith BK,Tomashek KM,Torres-Velasquez B,Alvarado LI,Lorenzi OD,Ramos C,Carrión J,Hunsperger E

更新日期：2020-01-29 00:00:00

abstract：BACKGROUND:Leishmania species are parasitic protozoa that have a tightly controlled cell cycle, regulated by cyclin-dependent kinases (CDKs). Cdc2-related kinase 3 (CRK3), an essential CDK in Leishmania and functional orthologue of human CDK1, can form an active protein kinase complex with Leishmania cyclins CYCA and C...

journal_title：PLoS neglected tropical diseases

authors： Walker RG,Thomson G,Malone K,Nowicki MW,Brown E,Blake DG,Turner NJ,Walkinshaw MD,Grant KM,Mottram JC

更新日期：2011-04-05 00:00:00

abstract：BACKGROUND:Amebic colitis, caused by intestinal infection with the parasite, Entamoeba histolytica, is a common cause of diarrhea worldwide. Fulminant amebic colitis is the most devastating complication of this infection, associated with both high mortality and morbidity. We conducted a review of the English literature...

journal_title：PLoS neglected tropical diseases

authors： Shirley DA,Moonah S

更新日期：2016-07-28 00:00:00

abstract：:The human mutilating disease chromoblastomycosis is caused by melanized members of the order Chaetothyriales. To assess population diversity among 123 clinical strains of agents of the disease in Brazil we applied sequencing of the rDNA internal transcribed spacer region, and partial cell division cycle and β-tubulin ...

journal_title：PLoS neglected tropical diseases

authors： Gomes RR,Vicente VA,Azevedo CM,Salgado CG,da Silva MB,Queiroz-Telles F,Marques SG,Santos DW,de Andrade TS,Takagi EH,Cruz KS,Fornari G,Hahn RC,Scroferneker ML,Caligine RB,Ramirez-Castrillon M,de Araújo DP,Heidrich D,Co

更新日期：2016-11-28 00:00:00

abstract：:Tick-borne rickettsioses are world-spreading infectious zoonoses. Ticks serve as reservoirs and vectors for Rickettsia and play a key role in transmission of rickettsioses. Most of the Chinese rickettsiosis patients are reported from Northeastern China but the distribution of tick and tick-borne Rickettsia species in ...

journal_title：PLoS neglected tropical diseases

authors： Shao JW,Zhang XL,Li WJ,Huang HL,Yan J

更新日期：2020-06-04 00:00:00

abstract：INTRODUCTION:Buruli Ulcer (BU) is caused by the environmental microbe Mycobacterium ulcerans. Despite unclear transmission, contact with a BU endemic region is the key known risk factor. In Victoria, Australia, where endemic areas have been carefully mapped, we aimed to estimate the Incubation Period (IP) of BU by inte...

journal_title：PLoS neglected tropical diseases

authors： Trubiano JA,Lavender CJ,Fyfe JA,Bittmann S,Johnson PD

更新日期：2013-10-03 00:00:00

abstract：:As the most widespread tick-borne arbovirus causing infections in numerous countries in Asia, Africa and Europe, Crimean-Congo Hemorrhagic Fever Virus (CCHFV, family Nairoviridae) was included in the WHO priority list of emerging pathogens needing urgent Research & Development attention. To ensure preparedness for pot...

journal_title：PLoS neglected tropical diseases

authors： Emmerich P,Mika A,von Possel R,Rackow A,Liu Y,Schmitz H,Günther S,Sherifi K,Halili B,Jakupi X,Berisha L,Ahmeti S,Deschermeier C

更新日期：2018-03-26 00:00:00