Common host-derived chemicals increase catches of disease-transmitting mosquitoes and can improve early warning systems for Rift Valley fever virus.

abstract：BACKGROUND:In 2012 the WHO formally recognised that infants and preschool children are at significant risk of schistosomiasis and qualify for treatment with praziquantel (PZQ). Targeted surveys determining both the performance and safety of this drug are now needed in endemic areas. We have formally assessed parasitolo...

journal_title：PLoS neglected tropical diseases

authors： Sousa-Figueiredo JC,Betson M,Atuhaire A,Arinaitwe M,Navaratnam AM,Kabatereine NB,Bickle Q,Stothard JR

更新日期：2012-01-01 00:00:00

abstract：:Two recombinant Fasciola hepatica antigens, saposin-like protein-2 (recSAP2) and cathepsin L-1 (recCL1), were assessed individually and in combination in enzyme-linked immunosorbent assays (ELISA) for the specific serodiagnosis of human fasciolosis in areas of low endemicity as encountered in Central Europe. Antibody ...

journal_title：PLoS neglected tropical diseases

authors： Gottstein B,Schneeberger M,Boubaker G,Merkle B,Huber C,Spiliotis M,Müller N,Garate T,Doherr MG

更新日期：2014-06-12 00:00:00

abstract：BACKGROUND:On the Zanzibar islands, United Republic of Tanzania, elimination of urogenital schistosomiasis is strived for in the coming years. This qualitative study aimed to better understand community knowledge, perceptions, and practices associated with schistosomiasis among school-aged children on Unguja and Pemba ...

journal_title：PLoS neglected tropical diseases

authors： Person B,Ali SM,A'Kadir FM,Ali JN,Mohammed UA,Mohammed KA,Rollinson D,Knopp S

更新日期：2016-07-11 00:00:00

abstract：BACKGROUND:Contacts of leprosy patients are at increased risk of developing leprosy and need to be targeted for early diagnosis. Seropositivity to the phenolic glycolipid I (PGL-I) antigen of Mycobacterium leprae has been used to identify contacts who have an increased risk of developing leprosy. In the present study, ...

journal_title：PLoS neglected tropical diseases

authors： Düppre NC,Camacho LA,Sales AM,Illarramendi X,Nery JA,Sampaio EP,Sarno EN,Bührer-Sékula S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Trachoma is a major cause of blindness in Southern Sudan. Its distribution has only been partially established and many communities in need of intervention have therefore not been identified or targeted. The present study aimed to develop a tool to improve targeting of survey and control activities. METHODS...

journal_title：PLoS neglected tropical diseases

authors： Clements AC,Kur LW,Gatpan G,Ngondi JM,Emerson PM,Lado M,Sabasio A,Kolaczinski JH

更新日期：2010-08-17 00:00:00

abstract：BACKGROUND:Taenia solium is a neglected zoonotic parasite endemic throughout many low-income countries worldwide, including Zambia, where it causes human and pig diseases with high health and socioeconomic burdens. Lack of knowledge is a recognized risk factor, and consequently targeted health educational programs can ...

journal_title：PLoS neglected tropical diseases

authors： Hobbs EC,Mwape KE,Devleesschauwer B,Van Damme I,Krit M,Berkvens D,Zulu G,Mambwe M,Chembensofu M,Trevisan C,Baauw J,Phiri IK,Speybroeck N,Ketzis J,Dorny P,Willingham AL,Gabriël S

更新日期：2019-05-20 00:00:00

abstract：BACKGROUND:Trachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious cause of blindness. Sequence-based analysis of the multiple strains typically present in endemic communities may be informative for epidemiology, transmission, response to treatment, and understanding the host response. METHODS:Conjun...

journal_title：PLoS neglected tropical diseases

authors： Andreasen AA,Burton MJ,Holland MJ,Polley S,Faal N,Mabey DC,Bailey RL

更新日期：2008-09-24 00:00:00

abstract：:Thromboembolic events were described in patients with Chagas disease without cardiomyopathy. We aim to confirm if there is a hypercoagulable state in these patients and to determine if there is an early normalization of hemostasis factors after antiparasitic treatment. Ninety-nine individuals from Chagas disease-endem...

journal_title：PLoS neglected tropical diseases

authors： Pinazo MJ,Posada Ede J,Izquierdo L,Tassies D,Marques AF,de Lazzari E,Aldasoro E,Muñoz J,Abras A,Tebar S,Gallego M,de Almeida IC,Reverter JC,Gascon J

更新日期：2016-01-04 00:00:00

abstract：BACKGROUND:Junín virus (JUNV), the etiologic agent of Argentine hemorrhagic fever (AHF), is classified by the NIAID and CDC as a Category A priority pathogen. Presently, antiviral therapy for AHF is limited to immune plasma, which is readily available only in the endemic regions of Argentina. T-705 (favipiravir) is a b...

journal_title：PLoS neglected tropical diseases

authors： Gowen BB,Juelich TL,Sefing EJ,Brasel T,Smith JK,Zhang L,Tigabu B,Hill TE,Yun T,Pietzsch C,Furuta Y,Freiberg AN

更新日期：2013-12-26 00:00:00

abstract：:Wolbachia bacteria are now being introduced into Aedes aegypti mosquito populations for dengue control. When Wolbachia infections are at a high frequency, they influence the local transmission of dengue by direct virus blocking as well as deleterious effects on vector mosquito populations. However, the effectiveness o...

journal_title：PLoS neglected tropical diseases

authors： Ross PA,Ritchie SA,Axford JK,Hoffmann AA

更新日期：2019-04-19 00:00:00

abstract：:Plasmodium vivax, one of the five species of Plasmodium parasites that cause human malaria, is responsible for 25-40% of malaria cases worldwide. Malaria global elimination efforts will benefit from accurate and effective genotyping tools that will provide insight into the population genetics and diversity of this par...

journal_title：PLoS neglected tropical diseases

authors： Baniecki ML,Faust AL,Schaffner SF,Park DJ,Galinsky K,Daniels RF,Hamilton E,Ferreira MU,Karunaweera ND,Serre D,Zimmerman PA,Sá JM,Wellems TE,Musset L,Legrand E,Melnikov A,Neafsey DE,Volkman SK,Wirth DF,Sabeti PC

更新日期：2015-03-17 00:00:00

abstract：:Mycobacterium tuberculosis complex (MTBC) comprises closely related species responsible for human and animal tuberculosis (TB). Efficient species determination is useful for epidemiological purposes, especially for the elucidation of the zoonotic contribution. In Algeria, data on MTBC genotypes are largely unknown. In...

journal_title：PLoS neglected tropical diseases

authors： Damene H,Tahir D,Diels M,Berber A,Sahraoui N,Rigouts L

更新日期：2020-11-30 00:00:00

abstract：:To obtain further insight into geographic distribution of Leishmania species in Peru, a countrywide survey, including central to southern rainforest areas where information on causative parasite species is limited, was performed based on cytochrome b (cyt b) and mannose phosphate isomerase (mpi) gene analyses. A total...

journal_title：PLoS neglected tropical diseases

authors： Kato H,Cáceres AG,Seki C,Silupu García CR,Holguín Mauricci C,Castro Martínez SC,Moreno Paico D,Castro Muniz JL,Troyes Rivera LD,Villegas Briones ZI,Guerrero Quincho S,Sulca Jayo GL,Tineo Villafuerte E,Manrique de Lara Estrada C

更新日期：2019-06-20 00:00:00

abstract：BACKGROUND:Leptospirosis is an emerging zoonosis that is often under-recognized in children and commonly confused with dengue in tropical settings. An enhanced ability to distinguish leptospirosis from dengue in children would guide clinicians and public health personnel in the appropriate use of limited healthcare res...

journal_title：PLoS neglected tropical diseases

authors： Libraty DH,Myint KS,Murray CK,Gibbons RV,Mammen MP,Endy TP,Li W,Vaughn DW,Nisalak A,Kalayanarooj S,Hospenthal DR,Green S,Rothman AL,Ennis FA

更新日期：2007-12-26 00:00:00

abstract：:Global distribution patterns of Cladophialophora carrionii, agent of human chromoblastomycosis in arid climates of Africa, Asia, Australia, Central-and South-America, were compared with similar data of the vicarious Fonsecaea spp., agents of the disease in tropical rain forests. Population diversities among 73 C. carr...

journal_title：PLoS neglected tropical diseases

authors： Deng S,Tsui CK,Gerrits van den Ende AH,Yang L,Najafzadeh MJ,Badali H,Li R,Hagen F,Meis JF,Sun J,Dolatabadi S,Papierok B,Pan W,de Hoog GS,Liao W

更新日期：2015-10-23 00:00:00

abstract：:Trypanosoma cruzi, the aetiological agent of Chagas disease possess extensive genetic diversity. This has led to the development of a plethora of molecular typing methods for the identification of both the known major genetic lineages and for more fine scale characterization of different multilocus genotypes within th...

journal_title：PLoS neglected tropical diseases

authors： Diosque P,Tomasini N,Lauthier JJ,Messenger LA,Monje Rumi MM,Ragone PG,Alberti-D'Amato AM,Pérez Brandán C,Barnabé C,Tibayrenc M,Lewis MD,Llewellyn MS,Miles MA,Yeo M

更新日期：2014-08-28 00:00:00

abstract：BACKGROUND:Singapore experiences endemic dengue, with 2013 being the largest outbreak year known to date, culminating in 22,170 cases. Given the limited resources available, and that vector control is the key approach for prevention in Singapore, it is important that public health professionals know where resources sho...

journal_title：PLoS neglected tropical diseases

authors： Ong J,Liu X,Rajarethinam J,Kok SY,Liang S,Tang CS,Cook AR,Ng LC,Yap G

更新日期：2018-06-18 00:00:00

abstract：BACKGROUND:Protozoan parasites of the genus Leishmania cause a large spectrum of clinical manifestations known as Leishmaniases. These diseases are increasingly important public health problems in many countries both within and outside endemic regions. Thus, an accurate differential diagnosis is extremely relevant for ...

journal_title：PLoS neglected tropical diseases

authors： Zampieri RA,Laranjeira-Silva MF,Muxel SM,Stocco de Lima AC,Shaw JJ,Floeter-Winter LM

更新日期：2016-02-29 00:00:00

abstract：BACKGROUND:Leptospirosis is a potentially fatal bacterial zoonosis that is endemic throughout the tropics and may be misdiagnosed as dengue. Delayed hospital admission of leptospirosis patients is associated with increased mortality. METHODOLOGY/PRINCIPAL FINDINGS:During a concurrent dengue/leptospirosis epidemic in P...

journal_title：PLoS neglected tropical diseases

authors： Sharp TM,Rivera García B,Pérez-Padilla J,Galloway RL,Guerra M,Ryff KR,Haberling D,Ramakrishnan S,Shadomy S,Blau D,Tomashek KM,Bower WA

更新日期：2016-02-25 00:00:00

abstract：:Soil-transmitted helminths (STH) are a major cause of morbidity in tropical developing countries with a global infection prevalence of more than one billion people and disease burden of around 3.4 million disability adjusted life years. Infection prevalence directly correlates to inadequate sanitation, impoverished co...

journal_title：PLoS neglected tropical diseases

authors： Stracke K,Clarke N,Awburn CV,Vaz Nery S,Khieu V,Traub RJ,Jex AR

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:Chagas disease is one of the most important neglected tropical diseases in the Americas. Vectorborne transmission of Chagas disease has been historically rare in urban settings. However, in marginal communities near the city of Arequipa, Peru, urban transmission cycles have become established. We examined th...

journal_title：PLoS neglected tropical diseases

authors： Bayer AM,Hunter GC,Gilman RH,Cornejo Del Carpio JG,Naquira C,Bern C,Levy MZ

更新日期：2009-12-15 00:00:00

abstract：:Andes virus (ANDV) is the etiological agent of hantavirus cardiopulmonary syndrome in Chile. In this study, we evaluated the profile of the pro-inflammatory cytokines IL-1β, IL-12p70, IL-21, TNF-α, IFN-γ, IL-10 and IL-6 in serum samples of ANDV-infected patients at the time of hospitalization. The mean levels of circu...

journal_title：PLoS neglected tropical diseases

authors： Angulo J,Martínez-Valdebenito C,Marco C,Galeno H,Villagra E,Vera L,Lagos N,Becerra N,Mora J,Bermúdez A,Díaz J,Ferrés M,López-Lastra M

更新日期：2017-07-14 00:00:00

abstract：BACKGROUND:Mali has become increasingly interested in the evaluation of transmission of both Wuchereria bancrofti and Onchocerca volvulus as prevalences of both infections move toward their respective elimination targets. The SD Bioline Onchocerciasis/LF IgG4 Rapid Test was used in 2 evaluation units (EU) to assess its...

journal_title：PLoS neglected tropical diseases

authors： Dolo H,Coulibaly YI,Dembele B,Guindo B,Coulibaly SY,Dicko I,Doumbia SS,Dembele M,Traore MO,Goita S,Dolo M,Soumaoro L,Coulibaly ME,Diallo AA,Diarra D,Zhang Y,Colebunders R,Nutman TB

更新日期：2019-01-30 00:00:00

abstract：BACKGROUND:A majority infections caused by dengue virus (DENV) are asymptomatic, but a higher incidence of severe illness, such as dengue hemorrhagic fever, is associated with secondary infections, suggesting that pre-existing immunity plays a central role in dengue pathogenesis. Primary infections are typically associ...

journal_title：PLoS neglected tropical diseases

authors： Chaudhury S,Gromowski GD,Ripoll DR,Khavrutskii IV,Desai V,Wallqvist A

更新日期：2017-02-21 00:00:00

abstract：INTRODUCTION:The agents of paracoccidioidomycosis, historically identified as Paracoccidioides brasiliensis, are in fact different phylogenetic species. This study aims to evaluate associations between Paracoccidioides phylogenetic species and corresponding clinical data. METHODS:Paracoccidioides strains from INI/Fioc...

journal_title：PLoS neglected tropical diseases

authors： de Macedo PM,Teixeira MM,Barker BM,Zancopé-Oliveira RM,Almeida-Paes R,Francesconi do Valle AC

更新日期：2019-04-15 00:00:00

abstract：:Dengue and chikungunya are viral diseases transmitted to humans by infected Aedes spp. mosquitoes. With an estimated 390 million infected people per year dengue virus (DENV) currently causes the most prevalent arboviral disease. During the last decade chikungunya virus (CHIKV) has caused large outbreaks and has expand...

journal_title：PLoS neglected tropical diseases

authors： Ruiz Silva M,Aguilar Briseño JA,Upasani V,van der Ende-Metselaar H,Smit JM,Rodenhuis-Zybert IA

更新日期：2017-06-23 00:00:00

abstract：BACKGROUND:The main objective of the study was to determine the degree of sensitization to Anisakis spp. antigens in healthy coastal population of Dalmatia given the high thermally unprocessed fish intake rate present in this area, suggested as a significant risk factor for anisakiasis. We performed a monocenter, cross...

journal_title：PLoS neglected tropical diseases

authors： Mladineo I,Poljak V,Martínez-Sernández V,Ubeira FM

更新日期：2014-02-06 00:00:00

abstract：BACKGROUND:Schistosomiasis japonica is a zoonotic parasitic disease. After nearly 70 years of control efforts in China, Schistosomiasis transmission has been reduced to a much lower level. The absence or near absence of infections in humans or livestock, based on traditional fecal and serological tests, has made the ta...

journal_title：PLoS neglected tropical diseases

authors： Qiu C,Zou HY,Deng Y,Liang YS,Lu DB

更新日期：2019-06-07 00:00:00

abstract：:Medical staff treating Coronavirus Disease 2019 (COVID-19) patients are at high risk for exposure to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), and many have been infected, which may cause panic among medical workers, their relatives, health professionals, and government leaders. We report the epide...

journal_title：PLoS neglected tropical diseases

authors： Li J,Long X,Zhang Q,Fang X,Li N,Lin Z,Li J,Xiong N

更新日期：2020-12-22 00:00:00

abstract：:Infected Ixodes scapularis (black-legged tick) transmit a host of serious pathogens via their bites, including Borrelia burgdorferi, Babesia microti, and tick-borne flaviviruses (TBFVs), such as Powassan virus (POWV). Although the role of female I. scapularis ticks in disease transmission is well characterized, the ro...

journal_title：PLoS neglected tropical diseases

authors： Kendall BL,Grabowski JM,Rosenke R,Pulliam M,Long DR,Scott DP,Offerdahl DK,Bloom ME

更新日期：2020-10-05 00:00:00