Abstract:
:[This corrects the article DOI: 10.3389/fncir.2018.00028.].
journal_name
Front Neural Circuitsjournal_title
Frontiers in neural circuitsauthors
Wen TC,Lall S,Pagnotta C,Markward J,Gupta D,Ratnadurai-Giridharan S,Bucci J,Greenwald L,Klugman M,Hill NJ,Carmel JBdoi
10.3389/fncir.2018.00080subject
Has Abstractpub_date
2018-09-25 00:00:00pages
80issn
1662-5110journal_volume
12pub_type
杂志文章,已发布勘误abstract::The primary (S1) and secondary (S2) somatosensory cortices project to several trigeminal sensory nuclei. One putative function of these corticofugal projections is the gating of sensory transmission through the trigeminal principal nucleus (Pr5), and some have proposed that S1 and S2 project differentially to the spin...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2015.00053
更新日期:2015-09-30 00:00:00
abstract::A fluorescent voltage sensor protein "Flare" was created from a Kv1.4 potassium channel with YFP situated to report voltage-induced conformational changes in vivo. The RNA virus Sindbis introduced Flare into neurons in the binocular region of visual cortex in rat. Injection sites were selected based on intrinsic optic...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2012.00015
更新日期:2012-03-22 00:00:00
abstract::Genetic labeling of neurons with a specific response feature is an emerging technology for precise dissection of brain circuits that are functionally heterogeneous at the single-cell level. While immediate early gene mapping has been widely used for decades to identify brain regions which are activated by external sti...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章,评审
doi:10.3389/fncir.2014.00037
更新日期:2014-04-23 00:00:00
abstract::The parahippocampal areas including the subiculum, pre- and parasubiculum, and notably the entorhinal cortex (EC) are intimately involved in the generation of limbic seizures in temporal lobe epilepsy. We investigated changes in the expression of 10 major GABAA receptor subunit mRNAs in subfields of the ventral hippoc...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2013.00142
更新日期:2013-09-18 00:00:00
abstract::Spike-timing dependent plasticity (STDP) is a biologically constrained unsupervised form of learning that potentiates or depresses synaptic connections based on the precise timing of pre-synaptic and post-synaptic firings. The effects of on-going STDP on the topology of evolving model neural networks were assessed in ...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2013.00070
更新日期:2013-04-18 00:00:00
abstract::How complex natural sounds are represented by the main converging center of the auditory midbrain, the central inferior colliculus, is an open question. We applied neural discrimination to determine the variation of detailed encoding of individual vocalizations across the best frequency gradient of the central inferio...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2015.00091
更新日期:2016-02-01 00:00:00
abstract::Both abnormalities of resting-state cerebral blood flow (CBF) and functional connectivity in Wilson's disease (WD) have been identified by several studies. Whether the coupling of CBF and functional connectivity is imbalanced in WD remains largely unknown. To assess this possibility, 27 patients with WD and 27 sex- an...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2019.00025
更新日期:2019-04-18 00:00:00
abstract::One of the large remaining challenges in the field of zebrafish neuroscience is the establishment of techniques and preparations that permit the recording and perturbation of neural activity in animals that can interact meaningfully with the environment. Since it is very difficult to do this in freely behaving zebrafi...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2012.00125
更新日期:2013-01-25 00:00:00
abstract::CORTICAL GABAERGIC INTERNEURONS IN RODENTS ORIGINATE IN THREE SUBCORTICAL REGIONS: the medial ganglionic eminence (MGE), the lateral/caudal ganglionic eminence (LGE/CGE), and the preoptic area (POA). Each of these neuroepithelial precursor domains contributes different interneuron subtypes to the cortex. Neuronal NOS ...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2012.00065
更新日期:2012-09-24 00:00:00
abstract::In addition to their ascending pathways that originate at the receptor cells, all sensory systems are characterized by extensive descending projections. Although the size of these connections often outweighs those that carry information in the ascending auditory pathway, we still have a relatively poor understanding o...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2012.00114
更新日期:2013-01-03 00:00:00
abstract::Gamma-amino butyric acid (GABA) is the major inhibitory neurotransmitter that is known to be synthesized and released from GABAergic neurons in the brain. However, recent studies have shown that not only neurons but also astrocytes contain a considerable amount of GABA that can be released and activate GABA receptors ...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章,评审
doi:10.3389/fncir.2014.00141
更新日期:2014-12-17 00:00:00
abstract::We have carried out a Gal4 enhancer trap screen in zebrafish, and have generated 184 stable transgenic lines with interesting expression patterns throughout the nervous system. Of these, three display clear expression in the tectum, each with a distinguishable and stereotyped distribution of Gal4 expressing cells. Det...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/neuro.04.013.2009
更新日期:2009-10-09 00:00:00
abstract::Neuronal activity is dominated by synaptic inputs from excitatory or inhibitory neural circuits. With the development of in vivo patch-clamp recording, especially in vivo voltage-clamp recording, researchers can not only directly measure neuronal activity, such as spiking responses or membrane potential dynamics, but ...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章,评审
doi:10.3389/fncir.2015.00023
更新日期:2015-05-22 00:00:00
abstract::Optogenetic stimulation of the mouse cortex can be used to generate motor maps that are similar to maps derived from electrode-based stimulation. Here we present a refined set of procedures for repeated light-based motor mapping in ChR2-expressing mice implanted with a bilateral thinned-skull chronic window and a chro...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2013.00123
更新日期:2013-07-25 00:00:00
abstract::Dopaminergic (DA) neurons represent <0.01% of neurons in the human brain, but are essential for normal neurological and psychiatric function. The majority of these neurons reside in the ventral midbrain, but they exert their profound influences on brain function through projections to both the cortex and the basal gan...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/neuro.04.003.2009
更新日期:2009-06-01 00:00:00
abstract::Homeostatic regulation of REM sleep drive, as measured by an increase in the number of REM sleep transitions, plays a key role in neuronal and behavioral plasticity (i.e., learning and memory). Deficits in REM sleep homeostatic drive (RSHD) are implicated in the development of many neuropsychiatric disorders. Yet, the...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2017.00063
更新日期:2017-09-14 00:00:00
abstract::The olfactory system has a unique capacity for recovery from peripheral damage. After injury to the olfactory epithelium (OE), olfactory sensory neurons (OSNs) regenerate and re-converge on target glomeruli of the olfactory bulb (OB). Thus far, this process has been described anatomically for only a few defined popula...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2013.00207
更新日期:2014-01-07 00:00:00
abstract::We investigate the importance of the degree of peripheral or central target differentiation for mouse auditory afferent navigation to the organ of Corti and auditory nuclei in three different mouse models: first, a mouse in which the differentiation of hair cells, but not central auditory nuclei neurons is compromised...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2017.00025
更新日期:2017-04-13 00:00:00
abstract::Open-source software development has skyrocketed in part due to community tools like github.com, which allows publication of code as well as the ability to create branches and push accepted modifications back to the original repository. As the number and size of EM-based datasets increases, the connectomics community ...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2019.00005
更新日期:2019-02-05 00:00:00
abstract::In this study, we explore the functional role of striatal cholinergic interneurons, hereinafter referred to as tonically active neurons (TANs), via computational modeling; specifically, we investigate the mechanistic relationship between TAN activity and dopamine variations and how changes in this relationship affect ...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2019.00010
更新日期:2019-02-21 00:00:00
abstract::"Dye-coupling", whole-mount immunohistochemistry for gap junction channel protein connexin 35 (Cx35), and freeze-fracture replica immunogold labeling (FRIL) reveal an abundance of electrical synapses/gap junctions at glutamatergic mixed synapses in the 14th spinal segment that innervates the adult male gonopodium of W...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2014.00066
更新日期:2014-06-26 00:00:00
abstract::Since the discovery of grid cells in rat entorhinal cortex, many models of their hexagonally arrayed spatial firing fields have been suggested. We review the models and organize them according to the mechanisms they use to encode position, update the positional code, read it out in the spatial grid pattern, and learn ...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2012.00016
更新日期:2012-04-18 00:00:00
abstract::How do local circuits in the inferior colliculus (IC) process and transform spectral and temporal sound information? Using a four-tetrode array we examined the functional properties of the IC and metrics of its micro circuitry by recording neural activity from neighboring single neurons in the cat. Spectral and tempor...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2012.00062
更新日期:2012-09-27 00:00:00
abstract::Caspase-3 is a cysteine protease that is most commonly associated with cell death. Recent studies have shown additional roles in mediating cell differentiation, cell proliferation and development of cell morphology. We investigated the role of caspase-3 in the development of chick auditory brainstem nuclei during embr...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2016.00084
更新日期:2016-10-24 00:00:00
abstract::Local field potentials (LFPs) in cortex reflect synchronous fluctuations in the synaptic activity of local populations of neurons. The power of high frequency (>30 Hz) oscillations in LFPs is locked to the phase of low frequency (<30 Hz) oscillations, an effect known as phase-amplitude coupling (PAC). While PAC has be...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2015.00082
更新日期:2015-12-22 00:00:00
abstract::Lateral neuronal interactions are known to play important roles in sensory information processing. A center-on surround-off local circuit arrangement has been shown to play a role in mediating contrast enhancement in the visual, auditory, and somatosensory systems. The lateral connectivity and the influence of those c...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2012.00034
更新日期:2012-05-31 00:00:00
abstract::Focal cortical dysplasias (FCDs) are a common cause of brain seizures and are often associated with intractable epilepsy. Here we evaluated aberrant brain neurophysiology in an in vivo mouse model of FCD induced by neonatal freeze lesions (FLs) to the right cortical hemisphere (near S1). Linear multi-electrode arrays ...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2016.00093
更新日期:2016-11-10 00:00:00
abstract::The perirhinal (PER) and entorhinal cortex (EC) receive input from the agranular insular cortex (AiP) and the subcortical lateral amygdala (LA) and the main output area is the hippocampus. Information transfer through the PER/EC network however, is not always guaranteed. It is hypothesized that this network actively r...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2016.00044
更新日期:2016-06-14 00:00:00
abstract::Multiple components of "γ-oscillations" between 30-170 Hz in the CA1 region of the hippocampus have been described, based on their coherence with oscillations in other brain regions and on their cross-frequency coupling with local θ-oscillations. However, it remains unclear whether the different sub-bands are generate...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2014.00150
更新日期:2015-01-12 00:00:00
abstract::mRNP granules at adult central synapses are postulated to regulate local mRNA translation and synapse plasticity. However, they are very poorly characterized in vivo. Here, in Drosophila olfactory synapses, we present early observations and characterization of candidate synaptic mRNP particles, one of which contains a...
journal_title:Frontiers in neural circuits
pub_type: 杂志文章
doi:10.3389/fncir.2010.00121
更新日期:2010-11-03 00:00:00