Modeling the effect of age in T1-2 breast cancer using the SEER database.

abstract：BACKGROUND:While epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) exert a breakthrough effect, the incidence of skin disorders as a side effect has significantly reduced patients' quality of life. This study aimed to develop a treatment for inflammatory ulcers as one of the side effects of afat...

journal_title：BMC cancer

authors： Sano K,Nakadate K,Hanada K

更新日期：2020-04-06 00:00:00

abstract：BACKGROUND:Altered expression of microRNAs (miRNAs) is known to contribute to cancer progression. miR-23b and miR-27b, encoded within the same miRNA cluster, are reported to have both tumor suppressive and oncogenic activity across human cancers, including breast cancer. METHODS:To clarify this dichotomous role in bre...

journal_title：BMC cancer

authors： Hannafon BN,Cai A,Calloway CL,Xu YF,Zhang R,Fung KM,Ding WQ

更新日期：2019-06-28 00:00:00

abstract：BACKGROUND:Leukemia is a cancer of blood and bone marrow cells, causing about 300,000 deaths worldwide. Photodynamic therapy (PDT) is a promising alternative for the treatment of malignant tumors. KillerRed is a genetically encoded red fluorescent protein photosensitizer (PS). In this study, we aimed to investigate the...

journal_title：BMC cancer

authors： Yuan M,Liu C,Li J,Ma W,Yu X,Zhang P,Ji Y

更新日期：2019-10-07 00:00:00

abstract：BACKGROUND:Rhabdoid tumors are rare cancers of early childhood arising in the kidney, central nervous system and other organs. The majority are caused by somatic inactivating mutations or deletions affecting the tumor suppressor locus SMARCB1 [OMIM 601607]. Germ-line SMARCB1 inactivation has been reported in associatio...

journal_title：BMC cancer

authors： Dagar V,Chow CW,Ashley DM,Algar EM

更新日期：2009-12-13 00:00:00

abstract：BACKGROUND:Cyclooxygenases (COX) play a key role in prostaglandin metabolism and are important for tumor development and progression. The aim of this study was to analyze the prognostic impact of COX-2 expression in a cohort of lymph node-negative breast cancer patients not treated in the adjuvant setting. METHODS:COX...

journal_title：BMC cancer

authors： Sicking I,Rommens K,Battista MJ,Böhm D,Gebhard S,Lebrecht A,Cotarelo C,Hoffmann G,Hengstler JG,Schmidt M

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:Data on cancers is a challenge in most developing countries. Population-based cancer registries are also not common in developing countries despite the usefulness of such registries in informing cancer prevention and control programmes. The availability of population-based data on cancers in Africa varies ac...

journal_title：BMC cancer

authors： Laryea DO,Awuah B,Amoako YA,Osei-Bonsu E,Dogbe J,Larsen-Reindorf R,Ansong D,Yeboah-Awudzi K,Oppong JK,Konney TO,Boadu KO,Nguah SB,Titiloye NA,Frimpong NO,Awittor FK,Martin IK

更新日期：2014-05-23 00:00:00

abstract：BACKGROUND:Pemphigus vulgaris (PV) is an autoimmune blistering disease of the skin and mucous membranes. Genital involvement occurs when most other common sites are concurrently affected or are in remission. Systemic lupus erythematosus (SLE) is an autoimmune disease that may affect many parts of the body and the skin ...

journal_title：BMC cancer

authors： Bifulco G,Mandato VD,Piccoli R,Giampaolino P,Mignogna C,Mignogna MD,Costagliola L,Nappi C

更新日期：2010-06-23 00:00:00

abstract：BACKGROUND:Therapeutic regulation of PPARdelta activity using selective agonists has been proposed for various disorders. However, the consequences of altered peroxisome proliferator-activated receptor delta (PPARdelta) activity in the context of intestinal tumourigenesis remain somewhat unclear. Contradictory evidence...

journal_title：BMC cancer

authors： Reed KR,Sansom OJ,Hayes AJ,Gescher AJ,Peters JM,Clarke AR

更新日期：2006-05-03 00:00:00

abstract：BACKGROUND:Increasing evidence suggests that alterations in mitochondrial DNA (mtDNA) content may be implicated in the tumorigenesis of several malignancies. However, the association between mtDNA content in peripheral blood lymphocytes (PBLs) and glioma risk has not been investigated. METHODS:Real-time PCR was used t...

journal_title：BMC cancer

authors： Zhang J,Li D,Qu F,Chen Y,Li G,Jiang H,Huang X,Yang H,Xing J

更新日期：2014-09-19 00:00:00

abstract：PURPOSE:Colorectal cancer (CRC) screening has been shown to decrease CRC mortality. Organised mass screening programs are being implemented in France. Its perception in the general population and by general practitioners is not well known. METHODS:Two nationwide observational telephone surveys were conducted in early ...

journal_title：BMC cancer

authors： Eisinger F,Cals L,Calazel-Benque A,Blay JY,Coscas Y,Dolbeault S,Namer M,Pivot X,Rixe O,Serin D,Roussel C,Morère JF,EDIFICE committee.

更新日期：2008-04-15 00:00:00

abstract：BACKGROUND:Bone mineral density (BMD) and lean mass (LM) may both decrease in breast cancer survivors, thereby increasing risk of falls and fractures. Research is needed to determine whether lean mass (LM) and fat mass (FM) independently relate to BMD in this patient group. METHODS:The Health, Eating, Activity, and Li...

journal_title：BMC cancer

authors： George SM,McTiernan A,Villaseñor A,Alfano CM,Irwin ML,Neuhouser ML,Baumgartner RN,Baumgartner KB,Bernstein L,Smith AW,Ballard-Barbash R

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) patients with hepatic vein tumor thrombosis (HVTT) extending to the inferior vena cava (IVC) have an extremely poor prognosis. Here we report a case of HCC with HVTT and renal dysfunction after hepatic arterial infusion chemotherapy (HAIC) successfully treated by liver resectio...

journal_title：BMC cancer

authors： Itoh A,Sadamori H,Yabushita K,Monden K,Tatsukawa M,Hioki M,Hyodo T,Omonishi K,Ueki T,Ohno S,Sakaguchi K,Takakura N

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate epigenetic status of cyclin A1 in human papillomavirus-associated cervical cancer. Y. Tokumaru et al., Cancer Res 64, 5982-7 (Sep 1, 2004)demonstrated in head and neck squamous-cell cancer an inverse correlation between cyclin A1 promoter hypermethylation and TP53 mutati...

journal_title：BMC cancer

authors： Kitkumthorn N,Yanatatsanajit P,Kiatpongsan S,Phokaew C,Triratanachat S,Trivijitsilp P,Termrungruanglert W,Tresukosol D,Niruthisard S,Mutirangura A

更新日期：2006-03-08 00:00:00

abstract：BACKGROUND:Melanoma can be lethal if not detected early and treated. Early detection can be facilitated via skin self-examination (SSE) and as such, SSE is part of melanoma follow-up care for individuals with a prior history, who face a life-long risk of reoccurrence. The objective of the current study was to identify ...

journal_title：BMC cancer

authors： Coroiu A,Moran C,Bergeron C,Drapeau M,Wang B,Kezouh A,Ernst J,Batist G,Körner A

更新日期：2020-02-14 00:00:00

abstract：BACKGROUND:Alterations in peripheral blood lymphocytes in cervical cancer have been reported, although conflicting views exist. The present study investigated the distributions of lymphocyte subsets in tumor tissue and peripheral blood samples from cervical cancer patients and precancerous lesion patients, and evaluate...

journal_title：BMC cancer

authors： Wu Y,Ye S,Goswami S,Pei X,Xiang L,Zhang X,Yang H

更新日期：2020-03-04 00:00:00

abstract：BACKGROUND:In people with albinism (PWA), the deficiency of melanin increase the risk of skin cancers. The aim of this study was to determine the prevalence of skin cancers and characteristics of these detected skin cancers (histological types, localization) in PWA in 10 cities in Togo in 2019. METHODS:This is a cross...

journal_title：BMC cancer

authors： Saka B,Akakpo SA,Teclessou JN,Gnossike P,Adam S,Mahamadou G,Kassang P,Elegbede Y,Mouhari-Toure A,Darre T,Kombate K,Pitché P

更新日期：2021-01-05 00:00:00

abstract：:After publication of the original article [1] the authors found that the article contained an incorrect version of Fig. 4. This does not affect the results and conclusions of the article. ...

journal_title：BMC cancer

authors： Kaveh F,Baumbusch LO,Nebdal D,Børresen-Dale AL,Lingjærde OC,Edvardsen H,Kristensen VN,Solvang HK

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:Budding is a complementary prognostic factor for colorectal cancer. In this study, we aimed to clarify the role of tumor budding in rectal cancer patients after preoperative chemoradiotherapy. METHODS:A total of 124 patients with rectal cancer treated with neoadjuvant chemoradiotherapy and consecutive surge...

journal_title：BMC cancer

authors： Trotsyuk I,Sparschuh H,Müller AJ,Neumann K,Kruschewski M,Horst D,Elezkurtaj S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Sexually transmitted Human Papilloma Virus (HPV) infection is a known risk factor for cancer of the anal canal in both men and women. CASE PRESENTATION:We describe a report of synchronous carcinoma of the anal canal in a heterosexual couple. High risk type 16 HPV DNA was detected in both tumors. CONCLUSION...

journal_title：BMC cancer

authors： Mendez LC,Hsieh E,Earle CC,Wong S

更新日期：2018-09-10 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are well recognized as gene regulators and have been implicated in the regulation of development as well as human diseases. miR-143 is located at a fragile site on chromosome 5 frequently deleted in cancer, and has been reported to be down-regulated in several cancers including colon cance...

journal_title：BMC cancer

authors： Gregersen LH,Jacobsen A,Frankel LB,Wen J,Krogh A,Lund AH

更新日期：2012-06-12 00:00:00

abstract：BACKGROUND:Despite being a mainstay for treating superficial bladder carcinoma and a promising agent for interstitial cystitis, the precise mechanism of Bacillus Calmette-Guerin (BCG) remains poorly understood. It is particularly unclear whether BCG is capable of altering gene expression beyond its well-recognized pro-...

journal_title：BMC cancer

authors： Saban MR,Hellmich HL,Simpson C,Davis CA,Lang ML,Ihnat MA,O'Donnell MA,Wu XR,Saban R

更新日期：2007-11-02 00:00:00

abstract：BACKGROUND:Heterogeneous nuclear ribonucleoproteins (hnRNPs) of the A/B type (hnRNP A1, A2/B1, A3) are highly related multifunctional proteins participating in alternative splicing by antagonising other splicing factors, notably ASF/SF2. The altered expression pattern of hnRNP A2/B1 and/or splicing variant B1 alone in ...

journal_title：BMC cancer

authors： Boukakis G,Patrinou-Georgoula M,Lekarakou M,Valavanis C,Guialis A

更新日期：2010-08-17 00:00:00

abstract：BACKGROUND:As a key gene in the immunosurveillance of cell malignancy, Cytotoxic T-lymphocyte antigen 4 (CTLA-4 is an important negative regulator of T cell activation and proliferation. The CTLA-4 +49G > A polymorphism is one of the most commonly studied polymorphisms in this gene due to its association with cancer ri...

journal_title：BMC cancer

authors： Zheng J,Yu X,Jiang L,Xiao M,Bai B,Lu J,Zhou Y

更新日期：2010-10-04 00:00:00

abstract：BACKGROUND:Radiation-induced parotid damage is one of the most common complications in patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy (RT). Intravoxel incoherent motion (IVIM) magnetic resonance (MR) imaging has been reported for evaluating irradiated parotid damage. However, the changes of IVIM p...

journal_title：BMC cancer

authors： Zhou N,Chu C,Dou X,Li M,Liu S,Zhu L,Liu B,Guo T,Chen W,He J,Yan J,Zhou Z,Yang X,Liu T

更新日期：2016-11-08 00:00:00

abstract：:It has been highlighted that in the original manuscript [1] Table S3 'An example of the predictive computational modeling process. Specific details on an annexure section of the PD-L1 pathway show the step-by-step reactions, mechanisms, and reaction equations that occur. Such reactions also occurred in all of the othe...

journal_title：BMC cancer

authors： Brogden KA,Parashar D,Hallier AR,Braun T,Qian F,Rizvi NA,Bossler AD,Milhem MM,Chan TA,Abbasi T,Vali S

更新日期：2018-04-12 00:00:00

abstract：BACKGROUND:Leukemia is different from solid tumor by harboring genetic rearrangements that predict prognosis and guide treatment strategy. PML-RARA, RUNX1-RUNX1T1, and KMT2A-rearrangement are common genetic rearrangements that drive the development of acute myeloid leukemia (AML). By contrast, rare genetic rearrangemen...

journal_title：BMC cancer

authors： Wang L,Sun Y,Sun Y,Meng L,Xu X

更新日期：2018-04-23 00:00:00

abstract：BACKGROUND:To assess the efficacy of salvage radiotherapy (RT) for persistent or rising PSA after radical prostatectomy and to determine prognostic factors identifying patients who may benefit from salvage RT. METHODS:Between 1990 and 2003, 59 patients underwent RT for PSA recurrence after radical prostatectomy. Patie...

journal_title：BMC cancer

authors： Quero L,Mongiat-Artus P,Ravery V,Maylin C,Desgrandchamps F,Hennequin C

更新日期：2008-01-29 00:00:00

abstract：BACKGROUND:The cholesterol biosynthesis pathway is typically upregulated in breast cancer. The role of NAD(P)-dependent steroid dehydrogenase-like (NSDHL) gene, which is involved in cholesterol biosynthesis, in breast cancer remains unknown. This study aimed to uncover the role of NSDHL in the growth and metastasis of ...

journal_title：BMC cancer

authors： Yoon SH,Kim HS,Kim RN,Jung SY,Hong BS,Kang EJ,Lee HB,Moon HG,Noh DY,Han W

更新日期：2020-05-04 00:00:00

abstract：BACKGROUND:Studies of human polyomavirus (HPyV) infection and lung cancer are limited and those regarding the association of human papillomavirus (HPV) infection and lung cancer have produced inconsistent results. METHODS:We conducted a nested case-control study to assess the association between incident lung cancer o...

journal_title：BMC cancer

authors： Colombara DV,Manhart LE,Carter JJ,Hawes SE,Weiss NS,Hughes JP,Qiao YL,Taylor PR,Smith JS,Galloway DA

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Extramural tumor deposits (TDs) and extracapsular lymph node involvement (ECLNI) are considered to be poor prognostic factors in patients with T3-4, N0-2, M0 colorectal cancer (CRC). Although TDs are known to have multiple origins and pleomorphic features, the prognostic significances of the different type o...

journal_title：BMC cancer

authors： Yamano T,Semba S,Noda M,Yoshimura M,Kobayashi M,Hamanaka M,Beppu N,Yano A,Tsukamoto K,Matsubara N,Tomita N

更新日期：2015-11-06 00:00:00