Impact of organised programs on colorectal cancer screening.

abstract：BACKGROUND:Desmoid tumour is a benign, non metastasising neoplasm characterised by an elevated deposition of organic macromolecules in the extracellular matrix (ECM). The matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases involved in the degradation of ECM macromolecules. The MMPs and their nat...

journal_title：BMC cancer

authors： Balducci C,Lilli C,Stabellini G,Marinucci L,Giustozzi G,Becchetti A,Cagini L,Locci P

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Molecular targeted therapy has emerged as a promising treatment of Hepatocellular carcinoma (HCC). One potential target is the Src family Kinase (SFK). C-Src, a non-receptor tyrosine kinase is a critical link of multiple signal pathways that regulate proliferation, invasion, survival, metastasis, and angioge...

journal_title：BMC cancer

authors： Chang AY,Wang M

更新日期：2013-05-30 00:00:00

abstract：BACKGROUND:Activating transcription factor-3 (ATF3) is involved in the complex process of cellular stress response. However, its exact role in cancer is discussed controversially because both tumor suppressive and oncogenic effects have been described. Here we followed-up on our previous observation that inhibition of ...

journal_title：BMC cancer

authors： Hackl C,Lang SA,Moser C,Mori A,Fichtner-Feigl S,Hellerbrand C,Dietmeier W,Schlitt HJ,Geissler EK,Stoeltzing O

更新日期：2010-12-03 00:00:00

abstract：BACKGROUND:For decades, planar bone scintigraphy has been the standard practice for detection of bone metastases in prostate cancer and has been endorsed by recent oncology/urology guidelines. It is a sensitive method with modest specificity. (18)F-fluoride positron emission tomography/computed tomography has shown imp...

journal_title：BMC cancer

authors： Fonager RF,Zacho HD,Langkilde NC,Petersen LJ

更新日期：2016-01-11 00:00:00

abstract：BACKGROUND:Well-designed clinical trials are of great importance in validating novel treatments and ensuring an evidence-based approach for sarcoma. This study aimed to provide a comprehensive landscape of the characteristics of metastatic or advanced sarcoma clinical trials using the substantial resource of the Clinci...

journal_title：BMC cancer

authors： Que Y,Xiao W,Xu BS,Wen XZ,Weng DS,Zhang X

更新日期：2018-12-13 00:00:00

abstract：BACKGROUND:The epithelial-mesenchymal transition (EMT) plays a pivotal role in various physiological processes, such as embryonic development, tissue morphogenesis, and wound healing. EMT also plays an important role in cancer invasion, metastasis, and chemoresistance. Additionally, EMT is partially responsible for che...

journal_title：BMC cancer

authors： Zhang Z,Zheng S,Lin Y,Sun J,Ding N,Chen J,Zhong J,Shi L,Xue M

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:SLIT-ROBO families of proteins mediate axon pathfinding and their expression is not solely confined to nervous system. Aberrant expression of SLIT-ROBO genes was repeatedly shown in a wide variety of cancers, yet data about their collective behavior in hepatocellular carcinoma (HCC) is missing. Hence, we qua...

journal_title：BMC cancer

authors： Avci ME,Konu O,Yagci T

更新日期：2008-12-29 00:00:00

abstract：BACKGROUND:Conditional survival (CS) measures the probability that patients will survive an additional number of years given that they have already survived for a certain period of time. METHODS:In total, 2935 gastric cancer patients who had undergone curative gastrectomy between 1995 and 2011 were enrolled. The Cox p...

journal_title：BMC cancer

authors： Lee JW,Ali B,Yoo HM,Park CH,Song KY

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:Hyponatraemia is a common finding in patients with cancer, and has been shown to be associated with poor prognosis in different settings. We have analysed the impact of severe hyponatraemia in patients with cancer. METHODS:A retrospective review of all patients admitted to a specialist cancer hospital with ...

journal_title：BMC cancer

authors： Balachandran K,Okines A,Gunapala R,Morganstein D,Popat S

更新日期：2015-03-22 00:00:00

abstract：BACKGROUND:High-risk neuroblastoma with N-Myc amplification remains a therapeutic challenge in paediatric oncology. Antagonism of pro-death Bcl-2 homology (BH) proteins to pro-survival BH members such as Mcl-1 and Bcl-2 has become a treatment approach, but previous studies suggest that a combined inhibition of Bcl-2 an...

journal_title：BMC cancer

authors： Klenke S,Akdeli N,Stelmach P,Heukamp L,Schulte JH,Bachmann HS

更新日期：2019-03-18 00:00:00

abstract：BACKGROUND:With the availability of effective anti-EGFR therapies for various solid malignancies, such as non-cell small lung cancer, colorectal cancer and squamous cell carcinoma of the head and neck, the knowledge of EGFR and K-RAS status becomes clinically important. The aim of this study was to analyse EGFR express...

journal_title：BMC cancer

authors： Van Damme N,Deron P,Van Roy N,Demetter P,Bols A,Van Dorpe J,Baert F,Van Laethem JL,Speleman F,Pauwels P,Peeters M

更新日期：2010-05-11 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the safety and efficacy of fractionated stereotactic radiotherapy (SRT) in combination with systemic therapies (ST) for brain metastases (BM). METHODS:Ninety-nine patients (171 BM) received SRT and concurrent ST (group 1) and 95 patients (131 BM) received SRT alone wit...

journal_title：BMC cancer

authors： Guénolé M,Lucia F,Bourbonne V,Dissaux G,Reygagne E,Goasduff G,Pradier O,Schick U

更新日期：2020-10-13 00:00:00

abstract：BACKGROUND:Gastric cancer is a considerable burden for worldwide patients. And diffuse gastric cancer is the most insidious subgroup with poor survival. The phenotypic characterization of the diffuse gastric cancer cell line can be useful for gastric cancer researchers. In this article, we aimed to characterize the dif...

journal_title：BMC cancer

authors： Yoon SJ,Park J,Shin Y,Choi Y,Park SW,Kang SG,Son HY,Huh YM

更新日期：2020-04-15 00:00:00

abstract：:After publication of the original article [1] the authors found that the article contained an incorrect version of Fig. 4. This does not affect the results and conclusions of the article. ...

journal_title：BMC cancer

authors： Kaveh F,Baumbusch LO,Nebdal D,Børresen-Dale AL,Lingjærde OC,Edvardsen H,Kristensen VN,Solvang HK

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:For the expanding population of bladder cancer survivors in Korea, the development of subsequent cancers is a significant concern. Here, we provide the second primary cancer incidence rates and types in Korean patients with bladder cancer. METHODS:Using population-based data from the Korea Central Cancer Re...

journal_title：BMC cancer

authors： Kwon WA,Joung JY,Lim J,Oh CM,Jung KW,Kim SH,Seo HK,Park WS,Chung J,Lee KH,Won YJ

更新日期：2018-05-31 00:00:00

abstract：BACKGROUND:Treatment of localized gastric cancer (LGC) consists of surgical resection followed by adjuvant treatment. Both chemoradiation (CRT) and chemotherapy (CT) regimens have shown benefit in survival outcomes versus observation. However, there are few data comparing these approaches. METHODS:This study included ...

journal_title：BMC cancer

authors： Girardi DM,de Lima MA,Pereira GCB,Negrão MV,López RVM,Capareli FC,Sabbaga J,Hoff PMG

更新日期：2018-04-03 00:00:00

abstract：BACKGROUND:Patients undergone kidney transplantation present higher risk of Urothelial Carcinoma (UC) development and represent a subgroup of special interest. To date, vinflunine is the only drug approved in Europe for the treatment of advanced UC after failure of platinum-based chemotherapy. However, to our knowledge...

journal_title：BMC cancer

authors： Bordi P,Tiseo M,Baldari G,Buti S

更新日期：2016-08-12 00:00:00

abstract：BACKGROUND:Subsyndromal delirium, a condition in which patients exhibit some, but not all, of the symptoms of delirium, can negatively affect the outcomes of patients with cancer. However, the incidence of subsyndromal delirium in patients with gastric cancer is unknown. Here, we investigated the incidence and risk fac...

journal_title：BMC cancer

authors： Hwang H,Lee KM,Son KL,Jung D,Kim WH,Lee JY,Kong SH,Suh YS,Lee HJ,Yang HK,Hahm BJ

更新日期：2018-07-27 00:00:00

abstract：BACKGROUND:Esophageal squamous cell carcinoma (ESCC) is a genetically complex tumor type and a major cause of cancer related mortality. Although distinct genetic alterations have been linked to ESCC development and prognosis, the genetic alterations have not gained clinical applicability. We applied array-based compara...

journal_title：BMC cancer

authors： Carneiro A,Isinger A,Karlsson A,Johansson J,Jönsson G,Bendahl PO,Falkenback D,Halvarsson B,Nilbert M

更新日期：2008-04-11 00:00:00

abstract：BACKGROUND:Since the second half of the 1990s, kidney cancer mortality has tended to stabilize and decline in many European countries, due to the decrease in the prevalence of smokers. Nevertheless, incidence of kidney cancer is rising across the sexes in some of these countries, a trend which may possibly reflect the ...

journal_title：BMC cancer

authors： López-Abente G,Aragonés N,Pérez-Gómez B,Ramis R,Vidal E,García-Pérez J,Fernández-Navarro P,Pollán M

更新日期：2008-10-09 00:00:00

abstract：BACKGROUND:The objective of this study was to describe the real-world treatment and overall survival (OS) of German patients with a diagnosis of advanced non-small cell lung cancer (aNSCLC), and to explore factors associated with the real-world mortality risk. METHODS:This was a retrospective German claims data analys...

journal_title：BMC cancer

authors： Hardtstock F,Myers D,Li T,Cizova D,Maywald U,Wilke T,Griesinger F

更新日期：2020-03-30 00:00:00

abstract：:Following publication of the original article [1], the authors reported an error in Figure 2, where the color code of the text boxes is reversed. Figure 2-amended shows the correct color association between the text boxes and the different areas in the map: Navarra, neighbouring communities and other Spanish communiti...

journal_title：BMC cancer

authors： de Sabando AR,Lafuente EU,García-Amigot F,Sánchez AA,Garofalo LM,Moreno S,Ardanaz E,Ramos-Arroyo MA

更新日期：2019-12-17 00:00:00

abstract：BACKGROUND:Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a benign lymphoid proliferation or malignant lymphoma in patients who have been treated with MTX. MTX withdrawal and observation for a short period should be considered in the initial management of patients who develop LPD while on MTX therapy...

journal_title：BMC cancer

authors： Watanabe S,Manabe O,Hirata K,Oyama-Manabe N,Hattori N,Kikuchi Y,Kobayashi K,Toyonaga T,Tamaki N

更新日期：2016-08-15 00:00:00

abstract：BACKGROUND:Pancreatic paragangliomas are rare tumors, with only 16 reported cases to date. One of these cases demonstrates metastasis to lymph node, while another case was functional, however, none of these cases showed malignant and large, pancreatic paraganglioma with marked invasion. Also another unique feature was ...

journal_title：BMC cancer

authors： Al-Jiffry BO,Alnemary Y,Khayat SH,Haiba M,Hatem M

更新日期：2013-10-20 00:00:00

abstract：BACKGROUND:Renal cell carcinoma (RCC) is a malignant disease that demonstrates resistance to standard chemotherapeutic agents. Yet Active immunization using genetically modified dendritic cells holds promise for the adjuvant treatment of malignancies to eradicate or control residual disease. Cytokine-induced killer (CI...

journal_title：BMC cancer

authors： Wang D,Zhang B,Gao H,Ding G,Wu Q,Zhang J,Liao L,Chen H

更新日期：2014-04-10 00:00:00

abstract：BACKGROUND:The objective of this retrospective study is to investigate laryngeal preservation and long-term treatment results in hypopharyngeal carcinoma treated with intensity-modulated radiotherapy (IMRT) combined with chemotherapy. METHODS:Twenty-seven patients with hypopharyngeal carcinoma (stage II-IV) were enrol...

journal_title：BMC cancer

authors： Liu WS,Hsin CH,Chou YH,Liu JT,Wu MF,Tseng SW,Lee JK,Tseng HC,Wang TH,Su MC,Lee H

更新日期：2010-03-18 00:00:00

abstract：BACKGROUND:The discovery of a solitary pulmonary nodule (SPN) on a chest imaging exam is of major clinical concern. However, the incidence rates of SPNs in a general population have not been estimated. The objective of this study was to provide incidence estimates of SPNs in a general population in 5 northeastern regio...

journal_title：BMC cancer

authors： Marrer É,Jolly D,Arveux P,Lejeune C,Woronoff-Lemsi MC,Jégu J,Guillemin F,Velten M

更新日期：2017-01-11 00:00:00

abstract：BACKGROUND:The origin and development of breast cancer remain complex and obscure. Recently, microRNA (miRNA) has been identified as an important regulator of the initiation and progression of breast cancer, and some studies have shown the essential role of miR-124-3p as a tumor suppressor in breast tumorigenesis. Howe...

journal_title：BMC cancer

authors： Wang Y,Chen L,Wu Z,Wang M,Jin F,Wang N,Hu X,Liu Z,Zhang CY,Zen K,Chen J,Liang H,Zhang Y,Chen X

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:The platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR), and neutrophil to lymphocyte ratio (NLR) reflect the systematic inflammatory response, with some evidence revealing that they are associated with poorer survival in patients with gastric cancer. However, the effect of the white blood...

journal_title：BMC cancer

authors： Zheng HL,Lu J,Xie JW,Wang JB,Lin JX,Chen QY,Cao LL,Lin M,Tu RH,Huang ZN,Lin JL,Li P,Zheng CH,Huang CM

更新日期：2019-11-21 00:00:00

abstract：BACKGROUND:Although radical surgery remains the cornerstone of cure in resectable gastric cancer, survival remains poor. Current evidence-based (neo)adjuvant strategies have shown to improve outcome, including perioperative chemotherapy, postoperative chemoradiotherapy and postoperative chemotherapy. However, these reg...

journal_title：BMC cancer

authors： Slagter AE,Jansen EPM,van Laarhoven HWM,van Sandick JW,van Grieken NCT,Sikorska K,Cats A,Muller-Timmermans P,Hulshof MCCM,Boot H,Los M,Beerepoot LV,Peters FPJ,Hospers GAP,van Etten B,Hartgrink HH,van Berge Henegouwen MI,

更新日期：2018-09-10 00:00:00