Risk of second primary Cancer among bladder Cancer patients: a population-based cohort study in Korea.

abstract：BACKGROUND:Recent randomized controlled trials comparing neoadjuvant chemoradiation plus surgery or perioperative chemotherapy plus surgery with surgery alone showed significant survival benefits for combined modality treatment of patients with localized esophageal adenocarcinoma. However, head-to-head comparisons of n...

journal_title：BMC cancer

authors： Hoeppner J,Lordick F,Brunner T,Glatz T,Bronsert P,Röthling N,Schmoor C,Lorenz D,Ell C,Hopt UT,Siewert JR

更新日期：2016-07-19 00:00:00

abstract：BACKGROUND:The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative per-oral carbohydrate load and their influence on tumor characteristics and survival. METHODS:The study...

journal_title：BMC cancer

authors： Lende TH,Austdal M,Bathen TF,Varhaugvik AE,Skaland I,Gudlaugsson E,Egeland NG,Lunde S,Akslen LA,Jonsdottir K,Janssen EAM,Søiland H,Baak JPA

更新日期：2019-12-04 00:00:00

abstract：BACKGROUND:The role of serine/threonine kinase 33 (STK33) gene in tumorigenesis is still controversial. This study was aimed to investigate whether STK33 had the effect on hypopharyngeal squamous cell carcinoma (HSCC) and relevant genes, as well as the potential relation to ERK1/2 pathway. METHODS:Immunohistochemistry...

journal_title：BMC cancer

authors： Huang L,Chen C,Zhang G,Ju Y,Zhang J,Wang H,Li J

更新日期：2015-01-21 00:00:00

abstract：BACKGROUND:In a recent pilot report, we showed that Smac/DIABLO mRNA is expressed de novo in a subset of cervical cancer patients. We have now expanded this study and analyzed Smac/DIABLO expression in the primary lesions in 109 cervical cancer patients. METHODS:We used immunohistochemistry of formalin-fixed, paraffin...

journal_title：BMC cancer

authors： Arellano-Llamas A,Garcia FJ,Perez D,Cantu D,Espinosa M,De la Garza JG,Maldonado V,Melendez-Zajgla J

更新日期：2006-10-26 00:00:00

abstract：BACKGROUND:We studied the cases of single and multiple HPV infection and analyzed the correlation with negative cases, and preneoplastic and neoplastic lesions of the uterine cervix with the aim of making a contribution to the prognostic factor under discussion. METHODS:Nine hundred nine women undergoing second level ...

journal_title：BMC cancer

authors： Bruno MT,Scalia G,Cassaro N,Boemi S

更新日期：2020-05-19 00:00:00

abstract：BACKGROUND:Pelvic nodal recurrences are being increasingly diagnosed with the introduction of new molecular imaging techniques, like choline and PSMA PET-CT, in the restaging of recurrent prostate cancer (PCa). At this moment, there are no specific treatment recommendations for patients with limited nodal recurrences a...

journal_title：BMC cancer

authors： De Bruycker A,Spiessens A,Dirix P,Koutsouvelis N,Semac I,Liefhooghe N,Gomez-Iturriaga A,Everaerts W,Otte F,Papachristofilou A,Scorsetti M,Shelan M,Siva S,Ameye F,Guckenberger M,Heikkilä R,Putora PM,Zapatero A,Conde-Mo

更新日期：2020-05-12 00:00:00

abstract：BACKGROUND:Recent reports indicate the existence of breast cancer cells expressing very high levels of the Arylhydrocarbon receptor (AhR), a ubiquitous intracellular receptor best known for mediating toxic action of dioxin and related pollutants. Positive correlation between the degree of AhR overexpression and states ...

journal_title：BMC cancer

authors： Wong PS,Li W,Vogel CF,Matsumura F

更新日期：2009-07-15 00:00:00

abstract：BACKGROUND:Protein secretion by mammary cells results in autocrine and paracrine signaling that defines cell growth, migration and the extracellular environment. Even so, we have a limited understanding of the cellular processes that regulate protein secretion. METHODS:In this study, we utilize human epithelial mammar...

journal_title：BMC cancer

authors： Zhang Y,Gonzalez RM,Zangar RC

更新日期：2011-02-14 00:00:00

abstract：BACKGROUND:The Nijmegen Breakage Syndrome is a chromosomal instability disorder characterized by microcephaly, growth retardation, immunodeficiency, and increased frequency of cancers. Familial studies on relatives of these patients indicated that they also appear to be at increased risk of cancer. METHODS:In a candid...

journal_title：BMC cancer

authors： Desjardins S,Beauparlant JC,Labrie Y,Ouellette G,Durocher F,INHERIT BRCAs.

更新日期：2009-06-12 00:00:00

abstract：BACKGROUND:This paper describes the development of a Cancer Awareness Measure for colorectal (CRC) cancer (Bowel/Colorectal CAMa) (study 1) and presents key results from a population-representative survey using the measure (study 2). METHODS:STUDY 1: Items were taken from the literature and reviewed by expert groups. ...

journal_title：BMC cancer

authors： Power E,Simon A,Juszczyk D,Hiom S,Wardle J

更新日期：2011-08-23 00:00:00

abstract：BACKGROUND:Total mesorectal excision is the standard surgical treatment for mid- and low-rectal cancer. Laparoscopy represents a clear leap forward in the management of rectal cancer patients, offering significant improvements in post-operative measures such as pain, first bowel movement, and hospital length of stay. H...

journal_title：BMC cancer

authors： Lelong B,de Chaisemartin C,Meillat H,Cournier S,Boher JM,Genre D,Karoui M,Tuech JJ,Delpero JR,French Research Group of Rectal Cancer Surgery (GRECCAR).

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:Aberrant spliced isoforms are specifically associated with cancer progression and metastasis. The cytoplasmic adaptor CRKL (v-crk avian sarcoma virus CT10 oncogene homolog-like) is a CRK like proto-oncogene, which encodes a SH2 and SH3 (src homology) domain-containing adaptor protein. CRKL is tightly linked ...

journal_title：BMC cancer

authors： Song Q,Yi F,Zhang Y,Jun Li DK,Wei Y,Yu H,Zhang Y

更新日期：2019-05-27 00:00:00

abstract：BACKGROUND:The present study evaluates the outcome of 19 children with rhabdomyosarcoma of the head-and-neck region treated with Intensity Modulated Radiotherapy (IMRT) or Fractionated Stereotactic Radiotherapy (FSRT) between August 1995 and November 2005. METHODS:We treated 19 children with head-and-neck rhabdomyosar...

journal_title：BMC cancer

authors： Combs SE,Behnisch W,Kulozik AE,Huber PE,Debus J,Schulz-Ertner D

更新日期：2007-09-13 00:00:00

abstract：BACKGROUND:Increasing studies have demonstrated that long non-coding RNAs (lncRNAs) play an important role in tumor progression. However, the potential biological functions and clinical importance of Linc01234 in oral squamous cell carcinoma (OSCC) remain unclear. METHODS:We evaluated the expression profile and progno...

journal_title：BMC cancer

authors： Liu D,Jian X,Xu P,Zhu R,Wang Y

更新日期：2020-02-10 00:00:00

abstract：BACKGROUND:Studies of human polyomavirus (HPyV) infection and lung cancer are limited and those regarding the association of human papillomavirus (HPV) infection and lung cancer have produced inconsistent results. METHODS:We conducted a nested case-control study to assess the association between incident lung cancer o...

journal_title：BMC cancer

authors： Colombara DV,Manhart LE,Carter JJ,Hawes SE,Weiss NS,Hughes JP,Qiao YL,Taylor PR,Smith JS,Galloway DA

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Allelic counterparts of biallelically expressed genes display an epigenetic symmetry normally manifested by synchronous replication, different from genes subjected to monoallelic expression, which normally are characterized by an asynchronous mode of replication (well exemplified by the SNRPN imprinted locus...

journal_title：BMC cancer

authors： Dotan ZA,Dotan A,Ramon J,Avivi L

更新日期：2008-12-25 00:00:00

abstract：BACKGROUND:It has been proposed that mesenchymal stromal cells (MSCs) promote tumor progression by interacting with tumor cells and other stroma cells in the complex network of the tumor microenvironment. We characterized MSCs isolated and expanded from tumor tissues of pediatric patients diagnosed with neuroblastomas ...

journal_title：BMC cancer

authors： Pelizzo G,Veschi V,Mantelli M,Croce S,Di Benedetto V,D'Angelo P,Maltese A,Catenacci L,Apuzzo T,Scavo E,Moretta A,Todaro M,Stassi G,Avanzini MA,Calcaterra V

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:Alcohol consumption is associated with higher breast cancer risk. While studies suggest a modest association between alcohol intake and mammographic density, few studies have examined the association in racial/ethnic minority populations. METHODS:We assessed dense breast area and total breast area from digi...

journal_title：BMC cancer

authors： Quandt Z,Flom JD,Tehranifar P,Reynolds D,Terry MB,McDonald JA

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Cancer patients routinely develop symptoms consistent with profound circadian disruption, which causes circadian disruption diminished quality of life. This study was initiated to determine the relationship between the severity of potentially remediable cancer-associated circadian disruption and quality of l...

journal_title：BMC cancer

authors： Grutsch JF,Ferrans C,Wood PA,Du-Quiton J,Quiton DF,Reynolds JL,Ansell CM,Oh EY,Daehler MA,Levin RD,Braun DP,Gupta D,Lis CG,Hrushesky WJ

更新日期：2011-05-23 00:00:00

abstract：BACKGROUND:Desmoid tumour is a benign, non metastasising neoplasm characterised by an elevated deposition of organic macromolecules in the extracellular matrix (ECM). The matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases involved in the degradation of ECM macromolecules. The MMPs and their nat...

journal_title：BMC cancer

authors： Balducci C,Lilli C,Stabellini G,Marinucci L,Giustozzi G,Becchetti A,Cagini L,Locci P

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:The value of chemotherapy in soft tissue sarcoma (STS) remains controversial. Several expert teams consider that chemotherapy provides a survival advantage and should be proposed in high-risk (HR) patients. However, the lack of accuracy in identifying HR patients with conventional risk factors (large, deep, ...

journal_title：BMC cancer

authors： Filleron T,Le Guellec S,Chevreau C,Cabarrou B,Lesluyes T,Lodin S,Massoubre A,Mounier M,Poublanc M,Chibon F,Valentin T

更新日期：2020-07-31 00:00:00

abstract：BACKGROUND:No scientific consensus has been reached on whether active tobacco smoking causes breast cancer. We examine the association between active smoking and breast cancer risk in Denmark, which has some of the highest smoking and breast cancer rates in women worldwide. METHODS:We used the data from a nationwide D...

journal_title：BMC cancer

authors： Andersen ZJ,Jørgensen JT,Grøn R,Brauner EV,Lynge E

更新日期：2017-08-22 00:00:00

abstract：BACKGROUND:Resistance to 5-fluorouracil (5-FU) in patients with colorectal cancer prevents effective treatment and leads to unnecessary and burdensome chemotherapy. Therefore, prediction of 5-FU resistance is imperative. METHODS:To identify the proteins linked to 5-FU resistance, two-dimensional gel electrophoresis-ba...

journal_title：BMC cancer

authors： Park JW,Kim SC,Kim WK,Hong JP,Kim KH,Yeo HY,Lee JY,Kim MS,Kim JH,Yang SY,Kim DY,Oh JH,Cho JY,Yoo BC

更新日期：2014-03-06 00:00:00

abstract：BACKGROUND:Thymidylate synthase (TS) and Topoisomerase I (Topo I) are significant biomarkers in colorectal cancer (CRC). We aimed to study the expression of TS and Topo I in patients with resected CRC who received adjuvant chemotherapy and correlated it with clinical outcome. METHODS:All patients diagnosed with CRC be...

journal_title：BMC cancer

authors： Kostopoulos I,Karavasilis V,Karina M,Bobos M,Xiros N,Pentheroudakis G,Kafiri G,Papakostas P,Vrettou E,Fountzilas G

更新日期：2009-09-24 00:00:00

abstract：BACKGROUND:Cell migration and invasion are essential processes for metastatic dissemination of cancer cells. Significant progress has been made in developing new therapies against oncogenic signaling to eliminate cancer cells and shrink tumors. However, inherent heterogeneity and treatment-induced adaptation to drugs c...

journal_title：BMC cancer

authors： Shahi Thakuri P,Gupta M,Singh S,Joshi R,Glasgow E,Lekan A,Agarwal S,Luker GD,Tavana H

更新日期：2020-01-02 00:00:00

abstract：BACKGROUND:In Australia, associations between geographic remoteness, socioeconomic disadvantage, and colorectal cancer (CRC) survival show that survival rates are lowest among residents of geographically remote regions and those living in disadvantaged areas. At present we know very little about the reasons for these i...

journal_title：BMC cancer

authors： Baade PD,Turrell G,Aitken JF

更新日期：2010-01-28 00:00:00

abstract：BACKGROUND:Oesophageal squamous cell carcinoma (OSCC) is a major health burden in Sub-Saharan Africa, and novel chemotherapies are urgently required to combat this disease. The heat shock protein 90 (HSP90) inhibitor 17-N-allylamino-17-demethoxygeldanamycin (17-AAG) has previously been proposed as a possible candidate ...

journal_title：BMC cancer

authors： Hadley KE,Hendricks DT

更新日期：2014-05-15 00:00:00

abstract：BACKGROUND:Studies have consistently indicated that the majority of individuals meeting the US Prevention Services Task Force guidelines for genetic testing have not had genetic counseling or testing. Despite increased availability and lower costs of multiplex cancer gene panels, there remains a gap in genetics service...

journal_title：BMC cancer

authors： Rayes N,Bowen DJ,Coffin T,Nebgen D,Peterson C,Munsell MF,Gavin K,Lechner R,Crase J,Polinsky D,Romero I,Blank SV,Levine DA,Norquist BM,Swisher EM,Lu KH

更新日期：2019-07-02 00:00:00

abstract：BACKGROUND:Many patients diagnosed with oesophageal adenocarcinoma (OAC) present with advanced disease and approximately half present with metastatic disease. Patients with localised disease, who are managed with curative intent, frequently undergo neoadjuvant chemoradiotherapy. Unfortunately, ~ 70% of patients have li...

journal_title：BMC cancer

authors： Bibby BAS,Miranda CS,Reynolds JV,Cawthorne CJ,Maher SG

更新日期：2019-08-07 00:00:00

abstract：BACKGROUND:High grade gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) with a Ki67 proliferation index > 20%, include well-differentiated tumours grade 3 (NET G3) and poorly differentiated (PD) neuroendocrine carcinomas (NEC). Abnormal p53-expression is a feature of PD tumours, while expression of chromogran...

journal_title：BMC cancer

authors： Nielsen K,Binderup T,Langer SW,Kjaer A,Knigge P,Grøndahl V,Melchior L,Federspiel B,Knigge U

更新日期：2020-01-10 00:00:00