Absence of an association of human polyomavirus and papillomavirus infection with lung cancer in China: a nested case-control study.

abstract：BACKGROUND:Pelvic inflammatory disease (PID) is characterized by infection and inflammation of the upper genital tract in women and is associated with health sequelae. We used a nationwide population-based retrospective cohort study to explore the relationship between PID and the subsequent development of gynecological...

journal_title：BMC cancer

authors： Shen CC,Hu LY,Yang AC,Chiang YY,Hung JH,Tsai SJ

更新日期：2016-11-03 00:00:00

abstract：BACKGROUND:Feline mammary carcinoma has been proposed as a natural model of highly aggressive, hormone-independent human breast cancer. To further explore the utility of the model by adding new similarities between the two diseases, we have analyzed the oncogene HER-2 status at both the protein and the gene levels. ME...

journal_title：BMC cancer

authors： Ordás J,Millán Y,Dios R,Reymundo C,de Las Mulas JM

更新日期：2007-09-20 00:00:00

abstract：BACKGROUND:This study was performed to create and validate a scoring system for the survival of patients with malignant spinal cord compression (SCC) from myeloma. METHODS:Of the entire cohort (N = 216), 108 patients were assigned to a test group and 108 patients to a validation group. In the test group, nine pre-trea...

journal_title：BMC cancer

authors： Douglas S,Schild SE,Rades D

更新日期：2012-09-25 00:00:00

abstract：BACKGROUND:Combinations of trastuzumab with either docetaxel or vinorelbine are considered valuable treatment options for HER2-positive metastatic breast cancer patients. We performed a retrospective comparison of the clinical outcomes associated with either one of these combinations. METHODS:From a multi-institutiona...

journal_title：BMC cancer

authors： Redana S,Donadio M,Nolè F,Jacomuzzi ME,Beano A,Martinello R,Sapino A,Viale G,Aglietta M,Montemurro F

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Treatment with recombinant human granulocyte-colony stimulating factor (G-CSF) is accepted standard for prevention of chemotherapy-induced neutropenia. RGB-02 (Gedeon Richter) is a proposed biosimilar to pegylated G-CSF (Neulasta®, Amgen) with sustained release properties. This is a randomized, comparative, ...

journal_title：BMC cancer

authors： Kahan Z,Grecea D,Smakal M,Tjulandin S,Bondarenko I,Perjesi L,Illes A,Horvat-Karajz K,Aradi I

更新日期：2019-02-06 00:00:00

abstract：BACKGROUND:Oncotype DX® (ODX) is used to assess risk of disease recurrence in hormone receptor positive, HER2-negative breast cancer and to guide decisions regarding adjuvant chemotherapy. Little is known about how physician factors impact treatment decisions. The purpose of this study was to examine patient and physic...

journal_title：BMC cancer

authors： Schwedhelm TM,Rees JR,Onega T,Zipkin RJ,Schaefer A,Celaya MO,Moen EL

更新日期：2020-09-03 00:00:00

abstract：BACKGROUND:3,3'-diindolylmethane (DIM) is an acid-catalyzed dimer of idole-3-carbinol (I3C), a phytochemical found in cruciferous vegetables that include broccoli, Brussels sprouts and cabbage. DIM is an aryl hydrocarbon receptor (AhR) ligand and a potential anticancer agent, namely for the treatment of breast cancer. ...

journal_title：BMC cancer

authors： Marques M,Laflamme L,Benassou I,Cissokho C,Guillemette B,Gaudreau L

更新日期：2014-07-21 00:00:00

abstract：BACKGROUND:The objective of this retrospective study is to investigate laryngeal preservation and long-term treatment results in hypopharyngeal carcinoma treated with intensity-modulated radiotherapy (IMRT) combined with chemotherapy. METHODS:Twenty-seven patients with hypopharyngeal carcinoma (stage II-IV) were enrol...

journal_title：BMC cancer

authors： Liu WS,Hsin CH,Chou YH,Liu JT,Wu MF,Tseng SW,Lee JK,Tseng HC,Wang TH,Su MC,Lee H

更新日期：2010-03-18 00:00:00

abstract：BACKGROUND:Angipoietin-1 activation of the tyrosine kinase receptor Tek expressed mainly on endothelial cells leads to survival and stabilization of endothelial cells. Studies have shown that Angiopoietin-1 counteracts permeability induced by a number of stimuli. Here, we test the hypothesis that loss of Angiopoietin-1...

journal_title：BMC cancer

authors： Michael IP,Orebrand M,Lima M,Pereira B,Volpert O,Quaggin SE,Jeansson M

更新日期：2017-08-11 00:00:00

abstract：BACKGROUND:It is well known that women suffer from negative consequences following breast cancer (BC) treatment and that their largely varying needs for rehabilitation are often unmet. Up to 43% of these women are at risk of developing chronic distress requiring complex interventions; however, how to early identify and...

journal_title：BMC cancer

authors： Olsson Möller U,Rydén L,Malmström M

更新日期：2020-05-29 00:00:00

abstract：BACKGROUND:Immune checkpoint inhibitors (ICIs) reported remarkable achievements in several solid tumours. However, in metastatic colorectal cancer (mCRC) promising results are limited to patients with deficient mismatch repair/microsatellite instability-high (dMMR/MSI-high) tumours due to their immune-enriched microenv...

journal_title：BMC cancer

authors： Antoniotti C,Borelli B,Rossini D,Pietrantonio F,Morano F,Salvatore L,Lonardi S,Marmorino F,Tamberi S,Corallo S,Tortora G,Bergamo F,Brunella DS,Boccaccino A,Grassi E,Racca P,Tamburini E,Aprile G,Moretto R,Boni L,Fa

更新日期：2020-07-22 00:00:00

abstract：BACKGROUND:Adequate circadian timing of cancer treatment schedules (chronotherapy) can enhance tolerance and efficacy several-fold in experimental and clinical situations. However, the optimal timing varies according to sex, genetic background and lifestyle. Here, we compute the individual phase of the Circadian Timing...

journal_title：BMC cancer

authors： Ortiz-Tudela E,Innominato PF,Rol MA,Lévi F,Madrid JA

更新日期：2016-04-21 00:00:00

abstract：BACKGROUND:Cervical dysplasia and tumorigenesis have been linked with numerous chromosomal aberrations. The goal of this study was to evaluate 35 genomic regions associated with cervical disease and to select those which were found to have the highest frequency of aberration for use as probes in fluorescent in-situ hyb...

journal_title：BMC cancer

authors： Policht FA,Song M,Sitailo S,O'Hare A,Ashfaq R,Muller CY,Morrison LE,King W,Sokolova IA

更新日期：2010-08-16 00:00:00

abstract：BACKGROUND:The aim of this study was to identify gene signatures and prognostic values of m6A methylation regulators in uveal melanoma (UM). METHODS:The RNA sequencing dataset and corresponding clinical information were downloaded from TCGA and GEO database. Based on the expression of m6A RNA methylation regulators, t...

journal_title：BMC cancer

authors： Tang J,Wan Q,Lu J

更新日期：2020-07-18 00:00:00

abstract：BACKGROUND:About 85% of breast cancer patients attending Komfo Anokye Teaching Hospital (KATH), Ghana, present with stage III/IV disease. In spite of great investments into the early diagnosis and management of breast cancer, late presentation persists and poses a barrier to realising the possible benefits of the gains...

journal_title：BMC cancer

authors： Agbeko AE,Arthur J,Bayuo J,Kaburi BB,Kyei I

更新日期：2020-10-19 00:00:00

abstract：BACKGROUND:Resilience has been linked to psychological adaptation to many challenging life events. The present study aims to explore the level of resilience in oral cancer patients and the key factors associated with resilience, and to evaluate the relationship between resilience and anxiety. METHODS:A multiple center...

journal_title：BMC cancer

authors： Gao Y,Yuan L,Pan B,Wang L

更新日期：2019-05-14 00:00:00

abstract：BACKGROUND:Although socioeconomic status (SES) has been focused on as a key determinant of cancer stage at diagosis in western countries, there has been no systemic study on the relationship of SES and breast cancer stage at diagnosis in China. METHODS:The medical charts of 4,211 eligible breast cancer patients from 7...

journal_title：BMC cancer

authors： Wang Q,Li J,Zheng S,Li JY,Pang Y,Huang R,Zhang BN,Zhang B,Yang HJ,Xie XM,Tang ZH,Li H,He JJ,Fan JH,Qiao YL

更新日期：2012-03-29 00:00:00

abstract：BACKGROUND:Understanding the complex, multistep process of metastasis remains a major challenge in cancer research. Metastasis models can reveal insights in tumor development and progression and provide tools to test new intervention strategies. METHODS:To develop a new cancer metastasis model, we used DU145 human pro...

journal_title：BMC cancer

authors： Banyard J,Chung I,Migliozzi M,Phan DT,Wilson AM,Zetter BR,Bielenberg DR

更新日期：2014-05-30 00:00:00

abstract：BACKGROUND:Intrahepatic cholangiocarcinomas are malignant tumors arising from the intrahepatic biliary tract. The pathogenesis of these tumors remains unknown. Although there is a marked global variation in prevalence, some recent studies have suggested an increase in mortality from intrahepatic cholangiocarcinoma in s...

journal_title：BMC cancer

authors： Patel T

更新日期：2002-05-03 00:00:00

abstract：BACKGROUND:Perturbing Hsp90 chaperone function targets hypoxia inducible factor (HIF) function in a von Hippel-Lindau (VHL) independent manner, and represents an approach to combat the contribution of HIF to cell renal carcinoma (CCRCC) progression. However, clinical trials with the prototypic Hsp90 inhibitor 17-AAG ha...

journal_title：BMC cancer

authors： Bohonowych JE,Peng S,Gopal U,Hance MW,Wing SB,Argraves KM,Lundgren K,Isaacs JS

更新日期：2011-12-15 00:00:00

abstract：BACKGROUND:The objective of this systematic review and meta-analysis was to determine the prognostic value of total tumor-infiltrating lymphocytes (TILs) and subtypes of TILs (CD4+, CD8+, and FOXP3+) in triple-negative breast cancer (TNBC). METHODS:A systematic search of the MEDLINE, EMBASE, and Web of Science databas...

journal_title：BMC cancer

authors： Gao G,Wang Z,Qu X,Zhang Z

更新日期：2020-03-04 00:00:00

abstract：BACKGROUND:Increasing studies have demonstrated that long non-coding RNAs (lncRNAs) play an important role in tumor progression. However, the potential biological functions and clinical importance of Linc01234 in oral squamous cell carcinoma (OSCC) remain unclear. METHODS:We evaluated the expression profile and progno...

journal_title：BMC cancer

authors： Liu D,Jian X,Xu P,Zhu R,Wang Y

更新日期：2020-02-10 00:00:00

abstract：BACKGROUND:cMyc and p27 are key genes implicated in carcinogenesis. Whether polymorphisms in these genes affect breast cancer risk or prognosis is still unclear. In this study, we focus on a rare non-synonymous polymorphism in cMyc (N11S) and a common polymorphism in p27 (V109G) and determine their role in risk and pro...

journal_title：BMC cancer

authors： Figueiredo JC,Knight JA,Cho S,Savas S,Onay UV,Briollais L,Goodwin PJ,McLaughlin JR,Andrulis IL,Ozcelik H

更新日期：2007-06-14 00:00:00

abstract：BACKGROUND:Obesity is associated with tumor aggressiveness and disease-specific mortality for more than 15 defined malignancies, including prostate cancer. Preclinical studies suggest that weight loss from caloric restriction and increased physical activity may suppress hormonal, energy-sensing, and inflammatory factor...

journal_title：BMC cancer

authors： Demark-Wahnefried W,Nix JW,Hunter GR,Rais-Bahrami S,Desmond RA,Chacko B,Morrow CD,Azrad M,Frugé AD,Tsuruta Y,Ptacek T,Tully SA,Segal R,Grizzle WE

更新日期：2016-02-05 00:00:00

abstract：BACKGROUND:BRCA1 and BRCA2 mutations are found in a proportion of families with multiple early-onset breast cancers. There are a large number of different deleterious mutations in both genes, none of which would be detectable using standard genetic association studies. Single common variants and haplotypes of common va...

journal_title：BMC cancer

authors： Turkovic L,Gurrin LC,Bahlo M,Dite GS,Southey MC,Hopper JL

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Nasopharyngeal carcinoma (NPC) is a highly invasive and metastatic cancer. N,N'-dinitrosopiperazine (DNP), a carcinogen with specificity for nasopharyngeal epithelium, facilitates NPC metastasis. However, the underlying mechanism is not known. METHODS:Quantitative phosphoproteomics, using stable isotope lab...

journal_title：BMC cancer

authors： Huang D,Li Y,Liu N,Zhang Z,Peng Z,Duan C,Tang X,Tan G,Yan G,Tang F

更新日期：2014-04-05 00:00:00

abstract：BACKGROUND:A substantial number of patients will develop further biochemical progression after radical prostatectomy (RP) and salvage radiotherapy (sRT). Recently published data using prostate-specific membrane antigen ligand positron emission tomography (PSMA - PET) for re-staging suggest that those recurrences are of...

journal_title：BMC cancer

authors： Oehus AK,Kroeze SGC,Schmidt-Hegemann NS,Vogel MME,Kirste S,Becker J,Burger IA,Derlin T,Bartenstein P,Eiber M,Mix M,la Fougère C,Belka C,Combs SE,Grosu AL,Müller AC,Guckenberger M,Christiansen H,Henkenberens C

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:Sarcomas are rare malignant tumors. Accurate initial histological diagnosis is essential for adequate management. We prospectively assessed the medical management of all patients diagnosed with sarcoma in a European region over a one-year period to identify the quantity of first diagnosis compared to central...

journal_title：BMC cancer

authors： Lurkin A,Ducimetière F,Vince DR,Decouvelaere AV,Cellier D,Gilly FN,Salameire D,Biron P,de Laroche G,Blay JY,Ray-Coquard I

更新日期：2010-04-19 00:00:00

abstract：BACKGROUND:The human leucine-rich, repeat-containing G protein-coupled receptor 5 (LGR5) is a stem cell marker in numerous adult tissues and is overexpressed in a large number of human carcinoma including colon cancer, breast cancer and oral squamous cell carcinomas (OSCC). The role of the full length transcript (LGR5F...

journal_title：BMC cancer

authors： Rot S,Kaune T,Taubert H,Greither T,Kotrba J,Güttler A,Wichmann H,Bilkenroth U,Wienke A,Al-Nawas B,Bache M,Vordermark D,Wickenhauser C,Bethmann D,Eckert AW,Kappler M

更新日期：2019-02-15 00:00:00

abstract：BACKGROUND:RNA from exosomes and other microvesicles contain transcripts of tumour origin. In this study we sought to identify biomarkers of glioblastoma multiforme in microvesicle RNA from serum of affected patients. METHODS:Microvesicle RNA from serum from patients with de-novo primary glioblastoma multiforme (N = 9...

journal_title：BMC cancer

authors： Noerholm M,Balaj L,Limperg T,Salehi A,Zhu LD,Hochberg FH,Breakefield XO,Carter BS,Skog J

更新日期：2012-01-17 00:00:00