Abstract:
BACKGROUND:Resilience has been linked to psychological adaptation to many challenging life events. The present study aims to explore the level of resilience in oral cancer patients and the key factors associated with resilience, and to evaluate the relationship between resilience and anxiety. METHODS:A multiple center cross-sectional study was carried out for Chinese patients with oral cancer between May 2016 and October 2017 in the Stomatology Hospital of China Medical University and Department of Stomatology, Shengjing Hospital of China Medical University. Two hundred and thirty oral cancer patients replied to the questionnaires on resilience, hope, perceived social support, optimism, perceived stress and anxiety which were measured with Resilience Scale-14 (RS-14), Herth Hope Index (HHI), Multidimensional Scale of Perceived Social Support (MSPSS), Revised Life Orientation Test (LOT-R), Perceived Stress Scale-10 (PSS-10) and Zung Self-Rating Anxiety Scale (SAS), respectively. Univariate one-way ANOVA/t-test, Pearson's r and hierarchical linear regression analysis were conducted to explore the influence factors of resilience and the relationship between resilience and anxiety. RESULTS:The level of resilience was 67.93 ± 12.65. Resilience was positively correlated with hope, optimism and perceived social support, and negatively correlated with perceived stress. Hierarchical linear regression analysis showed that hope (β = 0.386, P < 0.01), optimism (β = 0.190, P < 0.01) and education (β = 0.175, P < 0.01) were positively associated with resilience. The three variables in combination could explain 48.9% of the total variance in resilience. Higher level of resilience was associated less anxiety symptoms (X2 = 39.216, p = 0.000); and there was linear trend between resilience level and anxiety level among patients with oral cancer (X2 = 35.624, p = 0.000). CONCLUSION:Patients with oral cancer in China had moderate level of resilience. Hope, optimism and education were positively and significantly associated with resilience, indicating that higher level of hope, optimism and education may improve resilience in oral cancer patients, which in turn may help alleviate anxiety symptoms in patients.
journal_name
BMC Cancerjournal_title
BMC cancerauthors
Gao Y,Yuan L,Pan B,Wang Ldoi
10.1186/s12885-019-5679-0subject
Has Abstractpub_date
2019-05-14 00:00:00pages
447issue
1issn
1471-2407pii
10.1186/s12885-019-5679-0journal_volume
19pub_type
杂志文章,多中心研究相关文献
BMC CANCER文献大全abstract:BACKGROUND:Preclinical evidence suggests that aspirin may inhibit lung cancer progression. In a large cohort of lung cancer patients, we investigated whether low-dose aspirin use was associated with a reduction in the risk of lung cancer-specific mortality. METHODS:We identified lung cancer patients from English cance...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-015-1910-9
更新日期:2015-11-17 00:00:00
abstract:BACKGROUND:Spontaneous regression/complete resistance (SR/CR) mice are a unique colony of mice that possess an inheritable, natural cancer resistance mediated primarily by innate cellular immunity. This resistance is effective against sarcoma 180 (S180) at exceptionally high doses and these mice remain healthy. METHOD...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-10-179
更新日期:2010-05-03 00:00:00
abstract:BACKGROUND:The five-year survival rates for head and neck squamous cell carcinoma (HNSCC) patients are less than 50%, and the prognosis has not improved, despite advancements in standard multi-modality therapies. Hence major emphasis is being laid on identification of novel molecular targets and development of multi-ta...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-10-655
更新日期:2010-11-30 00:00:00
abstract:BACKGROUND:Several studies have described an increased cyclooxygenase-2 (COX-2) expression in pancreatic cancer, but the role of COX-2 in tumour development and progression is not clear. The aim of the present study was to examine expression of COX-2 in cancer cells and stromal cells in pancreatic cancer specimens, and...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-14-413
更新日期:2014-06-09 00:00:00
abstract:BACKGROUND:We report an extremely rare case of vaginal clear cell carcinoma, which originated from the malignant transformation of vaginal adenosis without prenatal diethylstilbestrol (DES) exposure. CASE PRESENTATION:In this case, the patient was a Chinese woman with a history of two decades of intermittent vaginal p...
journal_title:BMC cancer
pub_type: 杂志文章,评审
doi:10.1186/s12885-019-6026-1
更新日期:2019-08-13 00:00:00
abstract:BACKGROUND:Over-expression of HER2 in a subset of breast cancers (HER2+) is associated with high histological grade and aggressive clinical course. Despite these distinctive features, the differences in response of HER2+ patients to both adjuvant cytotoxic chemotherapy and targeted therapy (e.g. trastuzumab) suggests t...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-10-108
更新日期:2010-03-22 00:00:00
abstract:BACKGROUND:Aldo-keto reductase (AKR) 1C family member 3 (AKR1C3), one of four identified human AKR1C enzymes, catalyzes steroid, prostaglandin, and xenobiotic metabolism. In the prostate, AKR1C3 is up-regulated in localized and advanced prostate adenocarcinoma, and is associated with prostate cancer (PCa) aggressivenes...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-10-672
更新日期:2010-12-06 00:00:00
abstract:BACKGROUND:Recurrent/metastatic squamous cell carcinoma of the head and neck (SCCHN) has a poor prognosis and the combination of cisplatin and cetuximab, with or without 5-fluorouracil, is the gold standard treatment in this stage. Thus, the concomitant use of novel compounds represents a critical strategy to improve t...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2957-y
更新日期:2016-11-25 00:00:00
abstract:BACKGROUND:Renal cell carcinoma (RCC) is a malignant disease that demonstrates resistance to standard chemotherapeutic agents. Yet Active immunization using genetically modified dendritic cells holds promise for the adjuvant treatment of malignancies to eradicate or control residual disease. Cytokine-induced killer (CI...
journal_title:BMC cancer
pub_type: 临床试验,杂志文章
doi:10.1186/1471-2407-14-251
更新日期:2014-04-10 00:00:00
abstract:BACKGROUND:Of all female genital tract tumors, 1-3% are stromal malignancies. In 8-10% of cases, these are represented by Müllerian adenosarcoma an extremely rare tumor characterized by a stromal component of usually low-grade malignancy and by a benign glandular epithelial component. Variant that arises in the pouch o...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-11-171
更新日期:2011-05-15 00:00:00
abstract:BACKGROUND:Choriocarcinoma is a gestational trophoblastic tumor which causes high mortality if left untreated. MicroRNAs (miRNAs) are small non protein-coding RNAs which inhibit target gene expression. The role of miRNAs in choriocarcinoma, however, is not well understood. In this study, we examined the effect of miR-3...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-13-25
更新日期:2013-01-18 00:00:00
abstract:BACKGROUND:Prospective trials have demonstrated the advantage of dose-escalated radiotherapy for the biochemical and clinical control of intermediate risk prostate cancer. Dose escalation improves outcomes but increases risks of urinary and bowel toxicity. Recently the contribution of "spacers" positioned in the septum...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-018-4492-5
更新日期:2018-05-16 00:00:00
abstract:BACKGROUND:Pancreatic cancer remains the deadliest of all cancers, with a mortality rate of 91%. Gemcitabine is considered the gold chemotherapeutic standard, but only marginally improves life-span due to its chemical instability and low cell penetrance. A new paradigm to improve Gemcitabine's therapeutic index is to a...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-12-419
更新日期:2012-09-22 00:00:00
abstract:BACKGROUND:The nucleic acid mutation status in intracranial metastasis is markedly significant clinically. The goal of the current study was to explore whether the tumor-associated mutations can be detected by different next-generation sequencing (NGS) pipelines in paired cerebrospinal fluid (CSF) and plasma samples fr...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-019-5348-3
更新日期:2019-02-12 00:00:00
abstract:BACKGROUND:Identifying cellular signaling pathways that become corrupted in the presence of androgens that increase the metastatic potential of organ-confined tumor cells is critical to devising strategies capable of attenuating the metastatic progression of hormone-naïve, organ-confined tumors. In localized prostate c...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-015-1201-5
更新日期:2015-03-31 00:00:00
abstract:BACKGROUND:Utilisation of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and guide sheath (EBUS-GS) for diagnosis and staging of lung cancer is gaining popularity, however, its impact on clinical practice is unclear. This study aimed to determine the impact of the introduction of endobronc...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2081-z
更新日期:2016-01-28 00:00:00
abstract:BACKGROUND:Squamous cell carcinoma of the head and neck (SCCHN) often contain highly radioresistant hypoxic regions, nonetheless, radiotherapy is a common treatment modality for these tumours. Reoxygenation during fractionated radiotherapy is desired to render these hypoxic tumour regions more radiosensitive. Hypoxia a...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-7-143
更新日期:2007-07-30 00:00:00
abstract:BACKGROUND:It is well known that estrogen receptor α (ERα) participates in the pathogenic progress of breast cancer, hepatocellular carcinoma and head and neck squamous cell carcinoma. In neuroblastoma cells and related cancer clinical specimens, moreover, the ectopic expression of ERα has been identified. However, the...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-015-1495-3
更新日期:2015-06-30 00:00:00
abstract:BACKGROUND:Evasion of immune surveillance and suppression of the immune system are important hallmarks of tumorigenesis. The goal of this study was to establish distinct patterns that reflect a rectal tumors' immune-phenotype and to determine their relation to patient outcome. METHODS:The study population consisted of...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-14-486
更新日期:2014-07-05 00:00:00
abstract:BACKGROUND:Ectopic TSH-secreting pituitary adenoma (TSH-oma) is a very unusual disorder. To date, there are only four cases reported. It is difficult to distinguish ectopic cases from both regular TSH-omas and resistance to thyroid hormone (RTH). CASE PRESENTATION:A newly identified case of ectopic TSH-oma arising fro...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-14-544
更新日期:2014-07-28 00:00:00
abstract:BACKGROUND:Cigarette smoke is associated with the majority of lung cancers: however, 25% of lung cancer patients are non-smokers, and half of all newly diagnosed lung cancer patients are former smokers. Lung tumors exhibit distinct epidemiological, clinical, pathological, and molecular features depending on smoking sta...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-14-778
更新日期:2014-10-24 00:00:00
abstract:BACKGROUND:Non-muscle invasive bladder cancer (NMIBC) is usually treated with local therapy including transurethral resection of the bladder tumor and intravesical therapy depending on the stage of the tumor. NMIBC is a rarely a metastatic diseases with lymph node invasion in less of 10%. In the other hand meningeal ca...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-017-3309-2
更新日期:2017-05-11 00:00:00
abstract:BACKGROUND:The 5-year survival rate in patients with gastric cancer is still poor, and lymph node metastasis is considered one of the most important prognostic factors. However, there are controversies in the classification of lymph node metastasis in gastric cancer. This study was carried out to investigate whether th...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-7-200
更新日期:2007-10-24 00:00:00
abstract:BACKGROUND:To evaluate the role of blood vascular endothelial growth factor (VEGF) kinetics in patients with locally advanced esophageal squamous cell carcinoma (ESCC) receiving curative concurrent chemoradiotherapy (CCRT). METHODS:A total of 97 locally advanced ESCC patients were enrolled. All the patients had their ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-018-4731-9
更新日期:2018-08-20 00:00:00
abstract:BACKGROUND:Up to 80% of breast cancer patients suffer from Cancer Related Cognitive Impairments (CRCI). Exercise is suggested as a potential supportive care option to reduce cognitive decline in cancer patients. This study will investigate the effects of a high-intensity interval endurance training (HIIT) on CRCI in br...
journal_title:BMC cancer
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12885-018-4992-3
更新日期:2018-11-06 00:00:00
abstract:BACKGROUND:Human Papillomavirus (HPV) genotyping has an increasingly important role in cervical cancer screening and vaccination monitoring, however, without an internationally agreed standard reference assay. The test results from the most widely used genotyping assays are read manually and hence prone to inter-observ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-015-1223-z
更新日期:2015-04-02 00:00:00
abstract:BACKGROUND:Cationic antimicrobial peptides (CAPs) with antitumor activity constitute a promising group of novel anticancer agents. These peptides induce lysis of cancer cells through interactions with the plasma membrane. It is not known which cancer cell membrane components influence their susceptibility to CAPs. We h...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-9-183
更新日期:2009-06-15 00:00:00
abstract:BACKGROUND:CD73 has both enzymatic and non-enzymatic functions in cells. As a nucleotidase, CD73 plays its enzymatic function by catalyzing the hydrolysis of AMP into adenosine and phosphate. In addition to this, accumulating data have shown that CD73 is a key regulatory molecule involved in cancer growth and metastasi...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-017-3128-5
更新日期:2017-02-15 00:00:00
abstract:BACKGROUND:The PTEN tumour suppressor gene and PIK3CA proto-oncogene encode proteins which contribute to regulation and propagation of signal transduction through the PI3K/AKT signalling pathway. This study investigates the prevalence of loss of PTEN expression and mutations in both PTEN and PIK3CA in colorectal cancer...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-11-123
更新日期:2011-04-07 00:00:00
abstract:BACKGROUND:Neuroendocrine tumors (NETs) of the esophagus are extremely rare, and few cases have been reported worldwide. Thus, a comprehensive nationwide study is needed to understand the characteristics of and treatment strategy for esophageal NETs. METHODS:We collected data on esophageal NET patients from 25 hospita...
journal_title:BMC cancer
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2407-14-569
更新日期:2014-08-07 00:00:00