Disrupted resting-state spontaneous neural activity in stable COPD.

abstract：BACKGROUND:The relationship between prior health care utilization and respiratory medication prescriptions in an unselected population of patients with COPD is not known. METHODS:We determined the prescribed respiratory medications and respiratory and nonrespiratory health care encounters in 523 Veterans with COPD at ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Seaman J,Leonard AC,Panos RJ

更新日期：2010-04-07 00:00:00

abstract：:Cigarette smoking results in the accumulation of iron both systemically and locally, in the lung thereby causing imbalance in iron homeostasis. This disruption in iron homeostasis can be associated with oxidative stress and consequent tissue injury. Therefore, in this study, we tested the association between iron home...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ghio AJ,Hilborn ED

更新日期：2017-07-18 00:00:00

abstract：Purpose:Waterpipe (WP) use has become a global trend in young populations. However, there are few well-controlled studies focusing specifically on the chronic effects of exclusive WP use on young adults' respiratory health. We sought to compare in young adults the burden of respiratory symptoms in regular WP smokers (W...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hawari FI,Obeidat NA,Abu Alhalawa M,Al-Busaidi Z,Amara B,Baddar S,Elhabiby M,Elkholy H

更新日期：2019-08-13 00:00:00

abstract：:Bronchodilators represent the hallmark of symptomatic treatment of Chronic Obstructive Pulmonary Disease (COPD). There are four categories of bronchodilators: anticholinergics, methylxanthines, short-acting beta2-agonists, and long-acting beta2-agonists such as formoterol. Significant research has been performed to in...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Steiropoulos P,Tzouvelekis A,Bouros D

更新日期：2008-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality, and health care expenditure worldwide. Relaxation of airway smooth muscle with inhaled bronchodilators is the cornerstone of treatment for stable COPD, with inhaled corticosteroids reserved for those with a history of exacerbation...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cohen JS,Miles MC,Donohue JF,Ohar JA

更新日期：2016-04-15 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is one of the top five major causes of morbidity and mortality worldwide. Despite worldwide health care efforts, costs, and medical research, COPD figures demonstrate a continuously increasing tendency in mortality. This is contrary to other top causes of death, such as neo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hillas G,Perlikos F,Tzanakis N

更新日期：2016-07-13 00:00:00

abstract：BACKGROUND:Dry powder inhalers (DPIs) are inspiratory flow driven and hence flow dependent. Most patients with chronic obstructive pulmonary disease (COPD) are elderly and have poor lung function. The factors affecting their inspiratory flows through inhalers are unclear. OBJECTIVE:To study peak inspiratory flows (PIF...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Malmberg LP,Rytilä P,Happonen P,Haahtela T

更新日期：2010-08-09 00:00:00

abstract：Background:The risk of dying of lung cancer is up to eightfold higher in patients with COPD than in age- and gender-matched controls. The aim of this study was to investigate the factors associated with lung cancer in a large cohort of COPD patients from primary care centers. Methods:To analyze whether age, gender, so...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sandelin M,Mindus S,Thuresson M,Lisspers K,Ställberg B,Johansson G,Larsson K,Janson C

更新日期：2018-06-06 00:00:00

abstract：INTRODUCTION:Guidelines recommendations for the treatment of COPD are poorly followed. This could be related to the complexity of classification and treatment algorithms. The purpose of this study was to validate a simpler dyspnea-based treatment algorithm for inhaled pharmacotherapy in stable COPD, comparing its conco...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cabrera C,Casanova C,Martín Y,Mirabal V,Sánchez Mdel C,Álvarez F,Juliá G,Cabrera-Navarro P,García-Bello MÁ,Marín JM,de-Torres JP,Divo M,Celli B

更新日期：2016-06-08 00:00:00

abstract：Purpose:The unpredictable trajectory of COPD can present challenges for patients when faced with a decision regarding a do-not-resuscitate (DNR) directive. The current retrospective analysis was conducted to investigate factors associated with an early DNR decision (prior to last hospital admission) and differences in ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Fu PK,Tung YC,Wang CY,Hwang SF,Lin SP,Hsu CY,Chen DR

更新日期：2018-08-14 00:00:00

abstract：Background:Previous studies suggest that gender differences exist in COPD diagnosis and symptoms; these differences may be more pronounced in younger adults. Our objective was to explore age-associated gender differences across a range of COPD severities. Materials and methods:A total of 4,484 current and former smoke...

journal_title：International journal of chronic obstructive pulmonary disease

authors： DeMeo DL,Ramagopalan S,Kavati A,Vegesna A,Han MK,Yadao A,Wilcox TK,Make BJ,COPDGene Investigators.

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Presence of chronic obstructive pulmonary disease (COPD) in heart failure (HF) has prognostic and therapeutic implications. Exact prevalence estimates are lacking because most previous studies estimated the prevalence of COPD among HF patients while unstable and in the presence of pulmonary congestion. METH...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Valk MJ,Broekhuizen BD,Mosterd A,Zuithoff NP,Hoes AW,Rutten FH

更新日期：2015-06-26 00:00:00

abstract：:Impaired physical performance is common in chronic obstructive pulmonary disease (COPD), but its assessment can be difficult in routine clinical practice. We compared the timed up and go (TUG) test and other easily applied assessments of physical performance with the 6-minute walk distance (6MWD). In a longitudinal st...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Albarrati AM,Gale NS,Enright S,Munnery MM,Cockcroft JR,Shale DJ

更新日期：2016-08-02 00:00:00

abstract：Background:Although studies have examined the relationship between metabolic syndrome (MetS) and COPD, the incidence of MetS in individuals with COPD has not specifically been investigated. This study aimed to evaluate the incidence of MetS in subjects with airway obstruction using data from a community-based cohort. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim CY,Park Y,Leem AY,Chung KS,Jung JY,Park MS,Kim YS

更新日期：2018-06-28 00:00:00

abstract：BACKGROUND:The diagnosis and assessment of COPD rely mainly on the use of spirometry, which is an effort-dependent test and requires good patient cooperation. Impulse oscillometry (IOS) is a non-volitional method that requires less effort and cooperation and presents advantages for geriatric patients. However, the clin...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liu Z,Lin L,Liu X

更新日期：2017-03-15 00:00:00

abstract：:Frailty is a state of increased risk of unfavorable outcomes when exposed to stressors, and COPD is one of the several chronic illnesses associated with the condition. However, few studies have been conducted regarding the prevalence of COPD and its related factors in Southeast Asia. The objectives of this study were ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Limpawattana P,Putraveephong S,Inthasuwan P,Boonsawat W,Theerakulpisut D,Chindaprasirt J

更新日期：2017-04-18 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Pulmonary Daoyin (PD) (evolved from ancient Chinese daoyin skills), is a rehabilitation technology that combines specially designed movements of the arms and body and controlled breathing exercises, to improve the physiological and psychological status of patients with chronic respiratory disea...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhang HL,Li JS,Yu XQ,Li SY,Halmurat U,Xie Y,Wang YF,Li FS,Wang MH

更新日期：2017-08-04 00:00:00

abstract：:Regenerative or stem cell therapy is an emerging field of treatment based on stimulation of endogenous resident stem cells or administration of exogenous stem cells to treat diseases or injury and to replace malfunctioning or damaged tissues. Current evidence suggests that in the lung, these cells may participate in t...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lipsi R,Rogliani P,Calzetta L,Segreti A,Cazzola M

更新日期：2014-12-12 00:00:00

abstract：PURPOSE:Endobronchial valve (EBV) therapy is increasingly being seen as a therapeutic option for advanced emphysema, but its clinical utility in Asian populations, who may have different phenotypes to other ethnic populations, has not been assessed. PATIENTS AND METHODS:This prospective open-label single-arm clinical ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Park TS,Hong Y,Lee JS,Oh SY,Lee SM,Kim N,Seo JB,Oh YM,Lee SD,Lee SW

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:Cardiac autonomic modulation (CAM) is impaired in patients with stable COPD. Exacerbation aggravates the patients' health status and functional capacity. While the clinical and functional effects of exacerbation are known, no studies investigated CAM during exacerbation and whether there is a relationship be...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kabbach EZ,Mazzuco A,Borghi-Silva A,Cabiddu R,Agnoleto AG,Barbosa JF,de Carvalho Junior LCS,Mendes RG

更新日期：2017-07-28 00:00:00

abstract：:Health status questionnaires provide standardized measures of patients' perceptions of the impact of disease on their daily life and well-being. Factors associated with health status were examined in a sample of 58 outpatients with chronic obstructive pulmonary disease (COPD) and co-morbid anxiety and/or depression. A...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hynninen MJ,Pallesen S,Nordhus IH

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Comorbidities are characteristic of COPD. However, little is known about the secondary manifestations of COPD in the gastrointestinal tract. Therefore, we aimed to explore the long-term effects of gastrectomy in patients with spirometry-defined COPD or those at risk of COPD. PARTICIPANTS:Subjects included 87...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Saito H,Nomura K,Abe S,Motegi T,Ishii T,Hattori K,Kusunoki Y,Gemma A,Kida K

更新日期：2015-10-29 00:00:00

abstract：Purpose:Chronic obstructive pulmonary disease (COPD) is a major cause of chronic diseases causing considerable social and economic burden globally. Despite substantial evidence on temperature-COPD association, few studies have investigated the acute effect of temperature variability (TV), a potential trigger of exacerb...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhan ZY,Tian Q,Chen TT,Ye Y,Lin Q,Han D,Ou CQ

更新日期：2020-09-22 00:00:00

abstract：BACKGROUND:Assessment of dyspnea in COPD patients relies in clinical practice on the modified Medical Research Council (mMRC) scale, whereas the Baseline Dyspnea Index (BDI) is mainly used in clinical trials. Little is known on the correspondence between the two methods. METHODS:Cross-sectional analysis was carried ou...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Perez T,Burgel PR,Paillasseur JL,Caillaud D,Deslée G,Chanez P,Roche N,INITIATIVES BPCO Scientific Committee.

更新日期：2015-08-18 00:00:00

abstract：:The purpose of this study was to compare the relative efficacy and safety of different antibiotic drugs and recommend superior regimens in the treatment of bronchitis. With respect to the antibiotic comparisons against quinolones in terms of intention-to-treat patients, we concluded that quinolones had advantages over...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wang J,Xu H,Liu P,Li M

更新日期：2017-08-09 00:00:00

abstract：INTRODUCTION:While cross-national studies have documented rates of chronic obstructive pulmonary disease (COPD) misdiagnosis among patients in primary care, US studies are scarce. Studies investigating diagnosis among uninsured patients are lacking. OBJECTIVE:The purpose of this study is to identify patients who are o...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ghattas C,Dai A,Gemmel DJ,Awad MH

更新日期：2013-01-01 00:00:00

abstract：Background and purpose:While the efficacy and safety of combined tiotropium and olodaterol in patients with COPD was established in a large clinical trial program, it is important to assess whether clinical data can be applied to geographic patient groups, particularly for East Asian patients who may have a different p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bai C,Ichinose M,Lee SH,Lee KH,Jöns O,Bothner U,Zhao Y,Buhl R

更新日期：2017-11-20 00:00:00

abstract：Background:Previous studies have suggested that β2-adrenergic receptor (ADRB2) is associated with COPD. However, the role of genetic polymorphisms in ADRB2 on COPD has not been evaluated yet. Methods:In this study, SNaPshot genotyping, luciferase assay, chromatin immunoprecipitation and real-time polymerase chain reac...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Li JX,Fu WP,Zhang J,Zhang XH,Sun C,Dai LM,Zhong L,Yu L,Zhang YP

更新日期：2018-03-16 00:00:00

abstract：Objective:The presence of both emphysema and airway wall thickening determined via volumetric computed tomography (CT) is defined as mixed phenotype. The long-term clinical course of this phenotype has not been studied in depth. This study compared the mixed phenotype to other phenotypes of chronic obstructive pulmonar...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lim JU,Kim EK,Lim SY,Lee JH,Lee JS,Lee SD,Oh YM,Rhee CK,KOLD Study Group.

更新日期：2019-12-30 00:00:00

abstract：Background:Patients with chronic obstructive pulmonary disease (COPD) and cardiovascular comorbidities may have an increased risk of medication-related cardiac arrhythmias. We therefore performed an analysis of Holter electrocardiogram (ECG) data from two large, long-term, controlled clinical COPD trials to investigate...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Andreas S,Bothner U,de la Hoz A,Kloer I,Trampisch M,Alter P

更新日期：2020-08-10 00:00:00