Factors affecting health status in COPD patients with co-morbid anxiety or depression.

abstract：INTRODUCTION:Plasminogen activator inhibitor-1 (PAI-1), a major inhibitor of fibrinolysis, is associated with thrombosis, obesity, insulin resistance, dyslipidemia, and premature aging, which all are coexisting conditions of chronic obstructive pulmonary disease (COPD). The role of PAI-1 in COPD with respect to metabol...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Waschki B,Watz H,Holz O,Magnussen H,Olejnicka B,Welte T,Rabe KF,Janciauskiene S

更新日期：2017-03-22 00:00:00

abstract：:Currently, there is no cure for chronic obstructive pulmonary disease (COPD). The limited efficacy of current therapies for COPD indicates a pressing need to develop new treatments to prevent the progression of the disease, which consumes a significant amount of health care resources and is an important cause of morta...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Caramori G,Chung KF,Adcock IM

更新日期：2014-02-24 00:00:00

abstract：:The landmark study of Fletcher and Peto on the natural history of tobacco smoke-related chronic airflow obstruction suggested that decline in the forced expiratory volume in the first second (FEV(1)) in chronic obstructive pulmonary disease (COPD) is slow at the beginning, becoming faster with more advanced disease. T...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tantucci C,Modina D

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:The purpose of this study was to define the prevalence of undiagnosed airflow obstruction (AO) among subjects with a history of smoking but no previous diagnosis of chronic lung disease. The finding of AO likely represents diagnosis of chronic obstructive pulmonary disease. PATIENTS:People aged ≥30 years with ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Fu SN,Yu WC,Wong CK,Lam MC

更新日期：2016-09-27 00:00:00

abstract：INTRODUCTION:Effects of pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) patients with severely impaired health status are poorly documented since these patients are usually excluded from clinical trials. This retrospective, observational study aims to study the impact of disease on health ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van Ranst D,Otten H,Meijer JW,van 't Hul AJ

更新日期：2011-01-01 00:00:00

abstract：Purpose:This study investigated the effect of dual bronchodilation with the long-acting β-receptor agonist/long-acting muscarinic antagonist combination, indacaterol/glycopyrronium (IND/GLY), on nighttime oxygenation, lung function, sleep quality, and symptoms in patients with moderate-to-severe COPD. Patients and met...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lehmann S,Ringbæk T,Løkke A,Grote L,Hedner J,Lindberg E

更新日期：2019-01-09 00:00:00

abstract：:Despite the availability of guideline recommendations, diagnostic confusion between COPD and asthma appears common, and often it is very difficult to decide whether the obstruction is caused by asthma or COPD in a patient with airway obstruction. However, there are well-defined features that help in differentiating as...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Rogliani P,Ora J,Puxeddu E,Cazzola M

更新日期：2016-11-30 00:00:00

abstract：PURPOSE:A low body mass index has been associated with high mortalities in patients with chronic obstructive pulmonary disease (COPD), and studies reveal that obesity aggravates the clinical effects of COPD. We investigated the impact of obesity on patients newly identified with COPD. PATIENTS AND METHODS:This populat...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Park JH,Lee JK,Heo EY,Kim DK,Chung HS

更新日期：2017-02-24 00:00:00

abstract：PURPOSE:COPD is characterized by an accelerated and progressive decline in forced expiratory volume in 1 second (FEV1) and lung hyperinflation. Although lung hyperinflation is the hallmark of COPD, data on the longitudinal changes in lung hyperinflation and any association with the decline in FEV1 are lacking. The aim ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Park J,Lee CH,Lee YJ,Park JS,Cho YJ,Lee JH,Lee CT,Yoon HI

更新日期：2017-02-03 00:00:00

abstract：INTRODUCTION:End-stage lung disease (ESLD) (predominantly caused by chronic obstructive pulmonary disease and restrictive lung disease) is a significant cause of death. Little is known about community care for people with ESLD especially in the period leading to death. This paper describes demographic characteristics o...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Currow DC,Ward A,Clark K,Burns CM,Abernethy AP

更新日期：2008-01-01 00:00:00

abstract：:[This corrects the article on p. 1401 in vol. 12, PMID: 28546748.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:The combination of umeclidinium (UMEC), a long-acting muscarinic receptor antagonist, and vilanterol (VI), a selective long-acting β₂ agonist, is in development for the treatment of chronic obstructive pulmonary disease (COPD). This study evaluated the pharmacokinetics, safety and tolerability, and pharmacod...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Mehta R,Kelleher D,Preece A,Hughes S,Crater G

更新日期：2013-01-01 00:00:00

abstract：Background:Despite wide use of the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) 2011, little is known about between-stage transitions and what factors predict worsening transitions in patients with chronic obstructive pulmonary disease (COPD). Objective:To investigate the transition frequency bet...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bernabeu-Mora R,Sánchez-Martínez MP,Montilla-Herrador J,Oliveira-Sousa SL,Gacto-Sánchez M,Medina-Mirapeix F

更新日期：2020-06-30 00:00:00

abstract：Background:Static hyperinflation is known to be increased during moderate acute exacerbations of chronic obstructive pulmonary disease (COPD) (AECOPD), but few data exist in patients with severe exacerbations of COPD. The role of dynamic hyperinflation during exacerbations is unclear. Methods:In a prospective, observa...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van Geffen WH,Kerstjens HA

更新日期：2018-04-18 00:00:00

abstract：Background:COPD is considered an independent risk factor for lung cancer. COPD and lung cancer are both very heterogeneous diseases, and the study herein investigates the link between COPD phenotypes and specific histological subtypes of lung cancer. Methods:This case-control study comprised 2,283 patients with newly ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wang W,Xie M,Dou S,Cui L,Zheng C,Xiao W

更新日期：2018-04-13 00:00:00

abstract：Introduction:Long-term use of nebulized or oral antibiotics is common in the treatment of cystic fibrosis and non-cystic fibrosis bronchiectasis. To date, however, few studies have focused on the use of nebulized antibiotics in COPD patients. The aims of this study are: to establish whether a combination of nebulized c...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Montón C,Prina E,Pomares X,Cugat JR,Casabella A,Oliva JC,Gallego M,Monsó E

更新日期：2019-10-17 00:00:00

abstract：:COPD is a worsening condition that leads to a pathologic degeneration of the respiratory system. It represents one of the most important causes of mortality and morbidity in the world, and it is characterized by the presence of associated comorbidity. This article analyzes gastroesophageal reflux disease (GERD) and lo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bordoni B,Marelli F,Morabito B,Sacconi B,Caiazzo P,Castagna R

更新日期：2018-01-17 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is associated with an increased cardiovascular risk. However, the mechanisms for this association are yet unclear. The aim of this study was to investigate the relationship between brachial intima-media thickness (B-IMT), an independent predictor of cardiovascular...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Urban MH,Eickhoff P,Funk GC,Burghuber OC,Wolzt M,Valipour A

更新日期：2017-01-04 00:00:00

abstract：Purpose:This study compared the effects of inpatient-based rehabilitation program of patients with chronic obstructive pulmonary disease (COPD) using non-immersive virtual reality (VR) training with a traditional pulmonary rehabilitation program. The aims of this study were to determine 1) whether rehabilitation featur...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Rutkowski S,Rutkowska A,Kiper P,Jastrzebski D,Racheniuk H,Turolla A,Szczegielniak J,Casaburi R

更新日期：2020-01-13 00:00:00

abstract：:Background: Qualitative research provides real-life information on patients' condition and facilitates informed design of future clinical studies. Objective: We used Online Communities as a qualitative research tool to evaluate the effect of cough and mucus on COPD patients. Methods: Two 2-week Online Communities were...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cook N,Gey J,Oezel B,Mackay AJ,Kumari C,Kaur VP,Larkin N,Harte J,Vergara-Muro S,Gutzwiller FS

更新日期：2019-06-24 00:00:00

abstract：Background:Metabolic syndrome (MetS) is a well-known comorbidity of chronic obstructive pulmonary disease (COPD). However, their interrelationship, particularly in early COPD, remains unclear. Therefore, we aimed to assess the prevalence and clinical characteristics of MetS in patients with early COPD, and to explore t...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Choi HS,Rhee CK,Park YB,Yoo KH,Lim SY

更新日期：2019-12-10 00:00:00

abstract：Background:Microparticles (MPs) are shedding membrane vesicles released from activated blood and endothelial cells under inflammatory conditions. The role of endothelial MPs (EMPs) in pathophysiology of COPD is relatively well known. However, the release and function of MPs of other cellular origins, eg, platelets, red...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tőkés-Füzesi M,Ruzsics I,Rideg O,Kustán P,Kovács GL,Molnár T

更新日期：2018-11-15 00:00:00

abstract：Purpose:We compared clinical characteristics of COPD patients according to symptom variability and evaluated the effect of symptom variability during the first year of enrollment on clinical outcomes of COPD. Methods:We analyzed COPD patients' data from the Korean Obstructive Lung Disease (KOLD) cohort. Symptom variab...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim MA,Suh MK,Park J,Kim JH,Kim TH,Kim EK,Oh YM,Lee SD,Lee JH

更新日期：2019-09-20 00:00:00

abstract：PURPOSE:COPD remains under-recognized and under-treated. Much of early COPD care is given by primary care physicians but only when COPD is recognized. This survey explores the attitudes, beliefs, and knowledge related to COPD recognition, diagnosis, and treatment from family physicians and nurse practitioners (NPs) and...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Yawn BP,Wollan PC

更新日期：2008-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality, and health care expenditure worldwide. Relaxation of airway smooth muscle with inhaled bronchodilators is the cornerstone of treatment for stable COPD, with inhaled corticosteroids reserved for those with a history of exacerbation...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cohen JS,Miles MC,Donohue JF,Ohar JA

更新日期：2016-04-15 00:00:00

abstract：Introduction:COPD is an inflammatory airway pathology associated with recurrent infection by nontypeable Haemophilus influenzae (NTHi) that is not effectively managed by macrolide antibiotic therapy. We hypothesised that NTHi is able to reside intracellularly within COPD-derived airway epithelial cells (AEC), and that ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Poh WP,Kicic A,Lester SE,Nguyen PT,Bakaletz LO,Reynolds PN,Hodge S,Roscioli E

更新日期：2020-06-04 00:00:00

abstract：:Backgroud and objectives: Although lung attenuation distribution and lung volume on computed tomography (CT) have been widely used in evaluating COPD and interstitial lung disease, there are only a few studies regarding the normal range of these indices, especially in Chinese subjects. We aimed to describe the normal ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cheng T,Li Y,Pang S,Wan H,Shi G,Cheng Q,Li Q,Pan Z,Huang S

更新日期：2019-07-24 00:00:00

abstract：Background and Objectives:Long non-coding RNAs (lncRNAs) play an important role in the pathogenesis of many diseases, including cancer, pulmonary fibrosis and chronic obstructive pulmonary disease (COPD). In this study, we intended to identify the differentially expressed lncRNAs and the role of HOXA cluster antisense ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhou AY,Zhao YY,Zhou ZJ,Duan JX,Zhu YZ,Cai S,Chen P

更新日期：2020-10-09 00:00:00

abstract：Background:Phase III studies demonstrated efficacy and safety of nebulized glycopyrrolate inhalation solution (GLY) in subjects with COPD. Secondary analyses were performed to examine the effect of background long-acting beta2-agonist (LABA) use on the efficacy and safety of nebulized GLY. Methods:In two 12-week place...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kerwin EM,Tosiello R,Price B,Sanjar S,Goodin T

更新日期：2018-09-19 00:00:00

abstract：BACKGROUND:COPD is a major cause of death and morbidity worldwide, and is characterized by persistent airflow obstruction. The evaluation of obstruction is critically dependent on sensitive methods for lung-function testing. A wide body of knowledge has been accumulated in recent years showing that these methods have b...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lopes AJ,de Melo PL

更新日期：2016-07-11 00:00:00