Static and dynamic hyperinflation during severe acute exacerbations of chronic obstructive pulmonary disease.

abstract：Background:Since most internal medicine nurses work with chronic obstructive pulmonary disease (COPD) patients daily, their ability to meet the needs of COPD patients is an important issue. Our study aimed to assess COPD-related knowledge in internal medicine nurses. Methods:A descriptive cross-sectional study includi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ma Y,Peng Y,Chen P,Nie N,Chen Y

更新日期：2019-12-17 00:00:00

abstract：:COPD is a chronic inflammatory disease of the lungs associated with an abnormal inflammatory response to noxious particles, the most prevalent of which is cigarette smoke. Studies have demonstrated that cigarette smoking is associated with activation of the bone marrow, and chronic smoking can lead to the inflammatory...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Carlson AA,Smith EA,Reid DJ

更新日期：2015-10-22 00:00:00

abstract：Background and purpose:While the efficacy and safety of combined tiotropium and olodaterol in patients with COPD was established in a large clinical trial program, it is important to assess whether clinical data can be applied to geographic patient groups, particularly for East Asian patients who may have a different p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bai C,Ichinose M,Lee SH,Lee KH,Jöns O,Bothner U,Zhao Y,Buhl R

更新日期：2017-11-20 00:00:00

abstract：Rationale:Emphysema and osteoporosis are tobacco-related diseases. Many studies have shown that emphysema is a strong and independent predictor of low bone mineral density (BMD) in smokers; however, none of them explored its association with different emphysema subtypes. Objective:To explore the association between th...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Gonzalez J,Rivera-Ortega P,Rodríguez-Fraile M,Restituto P,Colina I,Calleja MLD,Alcaide AB,Campo A,Bertó J,Seijo L,Pérez-Warnisher MT,Zulueta JJ,Varo N,de-Torres JP

更新日期：2020-07-27 00:00:00

abstract：INTRODUCTION:According to guidelines, the diagnosis of COPD should be confirmed by post-bronchodilator (post-BD) airway obstruction on spirometry; however, in clinical practice, this is not always performed. The aim of this population-based study was to compare clinical characteristics and prognosis, assessed as mortal...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sawalha S,Hedman L,Rönmark E,Lundbäck B,Lindberg A

更新日期：2017-04-24 00:00:00

abstract：INTRODUCTION:Randomized interventional trials generally recruit highly selected patients. In contrast, long-term, noninterventional studies can reflect standard of care of real-life populations. DACCORD (Die ambulante Versorgung mit langwirksamen Bronchodilatatoren: COPD-Register in Deutschland [Outpatient Care With Lo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Buhl R,Criée CP,Kardos P,Vogelmeier C,Lossi N,Mailänder C,Worth H

更新日期：2016-07-20 00:00:00

abstract：BACKGROUND:Krasnoyarsk region is a territory with the widespread risk factors for chronic obstructive pulmonary disease (COPD) such as tobacco smoke, air pollution, and occupational exposure. An assessment of COPD prevalence based on medical diagnosis statistics underestimates the true COPD prevalence. This study aims ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Artyukhov IP,Arshukova IL,Dobretsova EA,Dugina TA,Shulmin AV,Demko IV

更新日期：2015-09-02 00:00:00

abstract：OBJECTIVES:COPD is an abnormal inflammatory response characterized by decreased expression of TLR2 in patients, which is suggested to induce invasive pulmonary aspergillosis (IPA). MicroRNAs (miRNAs) have been shown to play important roles in the pathogenesis of human respiratory system disorders. Therefore, the aim of...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xu H,Wu Y,Li L,Yuan W,Zhang D,Yan Q,Guo Z,Huang W

更新日期：2017-02-14 00:00:00

abstract：INTRODUCTION:Pulmonary emphysema causes several electrocardiogram changes, and one of the most common and well known is on the frontal P-wave axis. P-axis verticalization (P-axis > 60°) serves as a quasidiagnostic indicator of emphysema. The correlation of P-axis verticalization with the radiological severity of emphys...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chhabra L,Chaubey VK,Kothagundla C,Bajaj R,Kaul S,Spodick DH

更新日期：2013-01-01 00:00:00

abstract：:COPD is a major cause of chronic morbidity and mortality throughout the world. Although tumor necrosis factor-α (TNF-α) has a critical role in the development of COPD, the role of different TNF receptors (TNFRs) in pulmonary emphysema has not been resolved. We aimed to clarify the role of TNFRs in the development of p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Fujita M,Ouchi H,Ikegame S,Harada E,Matsumoto T,Uchino J,Nakanishi Y,Watanabe K

更新日期：2016-07-28 00:00:00

abstract：Background:Microparticles (MPs) are shedding membrane vesicles released from activated blood and endothelial cells under inflammatory conditions. The role of endothelial MPs (EMPs) in pathophysiology of COPD is relatively well known. However, the release and function of MPs of other cellular origins, eg, platelets, red...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tőkés-Füzesi M,Ruzsics I,Rideg O,Kustán P,Kovács GL,Molnár T

更新日期：2018-11-15 00:00:00

abstract：:COPD exerts a substantial burden on health and health care systems globally and will continue to do so for the foreseeable future. Treatment however can be costly and health care providers are interested in both whether treatments can offer improvements in disease burden and whether they represent value for money. Eco...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Starkie HJ,Briggs AH,Chambers MG

更新日期：2008-01-01 00:00:00

abstract：STUDY OBJECTIVES:Patients with chronic obstructive pulmonary disease (COPD) have low exercise capacity and low content of high energetic phosphates in their skeletal muscles. The aim of the present study was to investigate whether creatine supplementation together with exercise training may increase physical performanc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Faager G,Söderlund K,Sköld CM,Rundgren S,Tollbäck A,Jakobsson P

更新日期：2006-01-01 00:00:00

abstract：Introduction:Long-term use of nebulized or oral antibiotics is common in the treatment of cystic fibrosis and non-cystic fibrosis bronchiectasis. To date, however, few studies have focused on the use of nebulized antibiotics in COPD patients. The aims of this study are: to establish whether a combination of nebulized c...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Montón C,Prina E,Pomares X,Cugat JR,Casabella A,Oliva JC,Gallego M,Monsó E

更新日期：2019-10-17 00:00:00

abstract：Purpose:We hypothesized that increased level of serum β2-microglobulin (β2M) is an independent factor associated with higher mortality in hospitalized patients with exacerbated chronic obstructive pulmonary disease (COPD). Patients and Methods:We retrospectively analyzed 488 hospitalized patients with exacerbated COPD...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Mao W,Wang J,Zhang L,Wang Y,Wang W,Zeng N,Zhang J,Li Q,Jiao F,Li J,Cui N,Mi S,Xue Y,Wang Z,Ying S,Huang K

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:indacaterol is a novel, inhaled once-daily ultra-long-acting β(2)-agonist for the treatment of chronic obstructive pulmonary disease (COPD). OBJECTIVES:this study compared the onset of action of single doses of indacaterol 150 and 300 μg with salbutamol 200 μg, salmeterol-fluticasone 50/500 μg, and placebo ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Balint B,Watz H,Amos C,Owen R,Higgins M,Kramer B,INSURE Study Investigators.

更新日期：2010-09-07 00:00:00

abstract：Purpose:This study compared the effects of inpatient-based rehabilitation program of patients with chronic obstructive pulmonary disease (COPD) using non-immersive virtual reality (VR) training with a traditional pulmonary rehabilitation program. The aims of this study were to determine 1) whether rehabilitation featur...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Rutkowski S,Rutkowska A,Kiper P,Jastrzebski D,Racheniuk H,Turolla A,Szczegielniak J,Casaburi R

更新日期：2020-01-13 00:00:00

abstract：Background and objective:The distance of 6-minute walk test (D6MWT) has been widely used in the assessment of functional status in patients with COPD, while very little attention has been paid to the role of steps of 6-minute walk test (S6MWT). The purpose of this study was to investigate the relationship between S6MWT...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zeng GS,Chen LC,Fan HZ,Wu LL,Wu XP,Fang ZK,He X,Yu HP

更新日期：2018-12-28 00:00:00

abstract：Introduction and aim:Abnormal brain structure and function in COPD has been reported on MRI. However, the deficit in local synchronization of spontaneous activity in patients with stable COPD remains unknown. The main aim of the present study was to explore spontaneous brain activity in patients with COPD compared with...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xin H,Li H,Yu H,Yu J,Zhang J,Wang W,Peng D

更新日期：2019-02-27 00:00:00

abstract：BACKGROUND:The causal association between depression, anxiety, and health-related quality of life (HRQoL) in chronic obstructive pulmonary disease (COPD) is unclear. We therefore conducted a systematic review of prospective cohort studies that measured depression, anxiety, and HRQoL in COPD. METHODS:Electronic databas...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Blakemore A,Dickens C,Guthrie E,Bower P,Kontopantelis E,Afzal C,Coventry PA

更新日期：2014-05-20 00:00:00

abstract：Purpose:COPD has been associated with a high number of comorbidities and a relatively high level of health care resource utilization. This study aimed to estimate the social economic impact of COPD in the autonomous community of Extremadura (Spain) in 2015. Patients and methods:This is a retrospective observational st...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Merino M,Villoro R,Hidalgo-Vega Á,Carmona C

更新日期：2018-08-21 00:00:00

abstract：Background:Telerehabilitation (TR) aimed at patients with COPD has shown promising effects on symptoms, physical function, and quality of life, but little research has been conducted to understand the impact of implementation on frontline health professionals. Therefore, the aim of this study was to examine the barrier...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Damhus CS,Emme C,Hansen H

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is associated with an increased cardiovascular risk. However, the mechanisms for this association are yet unclear. The aim of this study was to investigate the relationship between brachial intima-media thickness (B-IMT), an independent predictor of cardiovascular...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Urban MH,Eickhoff P,Funk GC,Burghuber OC,Wolzt M,Valipour A

更新日期：2017-01-04 00:00:00

abstract：:[This corrects the article on p. 2749 in vol. 11, PMID: 27853362.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2017-01-10 00:00:00

abstract：Background:The DYNAGITO study was a Phase IIIb, randomized, double-blind, multicenter, active-controlled, parallel-group, 52-week study designed to determine the efficacy and safety of tiotropium and olodaterol combination therapy (TIO+OLO 5/5 μg) versus tiotropium monotherapy (TIO 5 μg) for reducing moderate-to-severe...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ichinose M,Nishimura M,Akimoto M,Kurotori Y,Zhao Y,de la Hoz A,Mishima M

更新日期：2018-07-13 00:00:00

abstract：:Bronchiectasis is defined by permanent and abnormal widening of the bronchi. This process occurs in the context of chronic airway infection and inflammation. It is usually diagnosed using computed tomography scanning to visualize the larger bronchi. Bronchiectasis is also characterized by mild to moderate airflow obst...

journal_title：International journal of chronic obstructive pulmonary disease

authors： King PT

更新日期：2009-01-01 00:00:00

abstract：Background:Despite wide use of the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) 2011, little is known about between-stage transitions and what factors predict worsening transitions in patients with chronic obstructive pulmonary disease (COPD). Objective:To investigate the transition frequency bet...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bernabeu-Mora R,Sánchez-Martínez MP,Montilla-Herrador J,Oliveira-Sousa SL,Gacto-Sánchez M,Medina-Mirapeix F

更新日期：2020-06-30 00:00:00

abstract：BACKGROUND:Dry powder inhalers (DPIs) are inspiratory flow driven and hence flow dependent. Most patients with chronic obstructive pulmonary disease (COPD) are elderly and have poor lung function. The factors affecting their inspiratory flows through inhalers are unclear. OBJECTIVE:To study peak inspiratory flows (PIF...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Malmberg LP,Rytilä P,Happonen P,Haahtela T

更新日期：2010-08-09 00:00:00

abstract：Purpose:Improvement in the diagnosis of asthma and chronic obstructive pulmonary disease (COPD) overlap (ACO), and identification of biomarkers for phenotype recognition will encourage good patient care by providing optimal therapy. We investigated club cell secretory protein (CC-16), a protective and anti-inflammatory...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Oh JY,Lee YS,Min KH,Hur GY,Lee SY,Kang KH,Rhee CK,Park SJ,Shim JJ

更新日期：2018-10-18 00:00:00

abstract：Background:Health effects of electronic cigarette (EC) use in patients with chronic obstructive pulmonary disease (COPD) are largely unexplored. Aim:We present findings from a long-term prospective assessment of respiratory parameters in a cohort of COPD patients who ceased or substantially reduced conventional cigare...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Polosa R,Morjaria JB,Prosperini U,Russo C,Pennisi A,Puleo R,Caruso M,Caponnetto P

更新日期：2018-08-22 00:00:00