Role of microparticles derived from monocytes, endothelial cells and platelets in the exacerbation of COPD.

abstract：BACKGROUND AND OBJECTIVE:The overprescription of inhaled corticosteroids (ICS) in the current Global Initiative for Chronic Obstructive Lung Disease (GOLD) group A and B patients with chronic obstructive pulmonary disease (COPD) is not uncommon in clinical practice. The aim of this study was to explore the factors asso...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wei YF,Kuo PH,Tsai YH,Tao CW,Cheng SL,Lee CH,Wu YK,Chen NH,Hsu WH,Hsu JY,Lin MS,Wang CC

更新日期：2015-09-14 00:00:00

abstract：:Bronchiectasis is defined by permanent and abnormal widening of the bronchi. This process occurs in the context of chronic airway infection and inflammation. It is usually diagnosed using computed tomography scanning to visualize the larger bronchi. Bronchiectasis is also characterized by mild to moderate airflow obst...

journal_title：International journal of chronic obstructive pulmonary disease

authors： King PT

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Circulating markers of inflammation in chronic obstructive pulmonary disease (COPD) may correlate to disease progression and extrapulmonary complications such as malnourishment. However, surprisingly little is known about gender-related differences for circulating inflammatory markers in COPD. PURPOSE:To ch...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Larsson S,Nordenson A,Glader P,Yoshihara S,Lindén A,Slinde F

更新日期：2011-01-01 00:00:00

abstract：STUDY OBJECTIVES:Patients with chronic obstructive pulmonary disease (COPD) have low exercise capacity and low content of high energetic phosphates in their skeletal muscles. The aim of the present study was to investigate whether creatine supplementation together with exercise training may increase physical performanc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Faager G,Söderlund K,Sköld CM,Rundgren S,Tollbäck A,Jakobsson P

更新日期：2006-01-01 00:00:00

abstract：:Bronchodilators represent the hallmark of symptomatic treatment of Chronic Obstructive Pulmonary Disease (COPD). There are four categories of bronchodilators: anticholinergics, methylxanthines, short-acting beta2-agonists, and long-acting beta2-agonists such as formoterol. Significant research has been performed to in...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Steiropoulos P,Tzouvelekis A,Bouros D

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:COPD-related deaths are increasing in Japan, with ~5.3 million people at risk. METHODS:The SHINE was a 26-week, multicenter, randomized, double-blind, parallel-group study that evaluated safety and efficacy of indacaterol (IND)/glycopyrronium (GLY) 110/50 μg once daily (od) compared with GLY 50 μg od, IND 1...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hashimoto S,Ikeuchi H,Murata S,Kitawaki T,Ikeda K,Banerji D

更新日期：2016-10-11 00:00:00

abstract：BACKGROUND:Prediction of future exacerbations of chronic obstructive pulmonary disease (COPD) is a major concern for long-term management of this disease. AIM:To determine which of three multidimensional assessment systems (the body mass index, obstruction, dyspnea, and exercise capacity [BODE] index; dyspnea, obstruc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Motegi T,Jones RC,Ishii T,Hattori K,Kusunoki Y,Furutate R,Yamada K,Gemma A,Kida K

更新日期：2013-01-01 00:00:00

abstract：Purpose:Epigenetic modification is one of most important mechanisms underlying the pathogenesis of chronic obstructive pulmonary disease (COPD). The purpose of this study was to determine whether histone acetyltransferase binding to ORC1 (HBO1) can protect against cigarette smoke (CS)-induced cell apoptosis and sustain...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chen L,Luo L,Kang N,He X,Li T,Chen Y

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:Krasnoyarsk region is a territory with the widespread risk factors for chronic obstructive pulmonary disease (COPD) such as tobacco smoke, air pollution, and occupational exposure. An assessment of COPD prevalence based on medical diagnosis statistics underestimates the true COPD prevalence. This study aims ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Artyukhov IP,Arshukova IL,Dobretsova EA,Dugina TA,Shulmin AV,Demko IV

更新日期：2015-09-02 00:00:00

abstract：:Influenza viruses cause respiratory tract infections that in patients with underlying lung diseases such as chronic obstructive pulmonary disease (COPD) are associated with exacerbations and excess morbidity and mortality. Typically, influenza B is associated with relatively mild, local outbreaks, whereas influenza A ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wesseling G

更新日期：2007-01-01 00:00:00

abstract：Background:The DYNAGITO study was a Phase IIIb, randomized, double-blind, multicenter, active-controlled, parallel-group, 52-week study designed to determine the efficacy and safety of tiotropium and olodaterol combination therapy (TIO+OLO 5/5 μg) versus tiotropium monotherapy (TIO 5 μg) for reducing moderate-to-severe...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ichinose M,Nishimura M,Akimoto M,Kurotori Y,Zhao Y,de la Hoz A,Mishima M

更新日期：2018-07-13 00:00:00

abstract：:Measurement of inspiratory capacity (IC) as a marker of dynamic lung hyperinflation has been shown to correlate with dyspnea and exercise performance in stable COPD, and is therefore of potential utility in the management of this condition. We have examined whether similar relationships exist during acute exacerbation...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pretto JJ,McMahon MA,Rochford PD,Berlowitz DJ,Jones SM,Brazzale DJ,McDonald CF

更新日期：2007-01-01 00:00:00

abstract：Background:Airway inflammation may drive the progression of chronic obstructive pulmonary disease (COPD) associated with alpha-1 antitrypsin deficiency (AATD), but the relationship between airway microbiota and inflammation has not been investigated. Methods:We studied 21 non-treated AATD (AATD-noT) patients, 20 AATD-...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Balbi B,Sangiorgi C,Gnemmi I,Ferrarotti I,Vallese D,Paracchini E,Delle Donne L,Corda L,Baderna P,Corsico A,Carone M,Brun P,Cappello F,Ricciardolo FL,Ruggeri P,Mumby S,Adcock IM,Caramori G,Di Stefano A

更新日期：2019-08-21 00:00:00

abstract：Introduction:Self-management (SM) is a core component of well-being and perceived health for patients with chronic obstructive pulmonary disease (COPD). Most theories on SM share that self-efficacy, illness-perception and coping are determinants of SM behavior. Optimal support to improve SM should be tailored to the in...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Voorhaar M,Tiemensma J,Asijee GM,Slok AHM,Muris JWM,Kaptein AA

更新日期：2020-06-19 00:00:00

abstract：Purpose:miR-190a-5p expression alters dynamically in response to hypoxia. However, the role of miR-190a-5p expression in hypoxia-induced pulmonary hypertension (PH) remains unclear. We sought to correlate the miR-190a-5p expression levels with the severity, diagnosis, and prognosis of PH in relation to chronic obstruct...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jiang J,Xia Y,Liang Y,Yang M,Zeng W,Zeng X

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:Assessment of dyspnea in COPD patients relies in clinical practice on the modified Medical Research Council (mMRC) scale, whereas the Baseline Dyspnea Index (BDI) is mainly used in clinical trials. Little is known on the correspondence between the two methods. METHODS:Cross-sectional analysis was carried ou...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Perez T,Burgel PR,Paillasseur JL,Caillaud D,Deslée G,Chanez P,Roche N,INITIATIVES BPCO Scientific Committee.

更新日期：2015-08-18 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether long-term intermittent azithromycin therapy reduces the frequency of exacerbation in severe chronic obstructive pulmonary disease (COPD). METHODS:We retrospectively investigated the clinical benefits of long-term azithromycin (500 mg orally three times per week...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pomares X,Montón C,Espasa M,Casabon J,Monsó E,Gallego M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:There is conflicting information regarding the effects of selective and nonselective beta-blocker treatment in patients with COPD. PARTICIPANTS AND METHODS:This nested case-control study used the Taiwan National Health Insurance Research Database. We included COPD patients who used inhalation steroid and be...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Huang YL,Lai CC,Wang YH,Wang CY,Wang JY,Wang HC,Yu CJ,Chen L

更新日期：2017-10-11 00:00:00

abstract：:Frailty is a state of increased risk of unfavorable outcomes when exposed to stressors, and COPD is one of the several chronic illnesses associated with the condition. However, few studies have been conducted regarding the prevalence of COPD and its related factors in Southeast Asia. The objectives of this study were ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Limpawattana P,Putraveephong S,Inthasuwan P,Boonsawat W,Theerakulpisut D,Chindaprasirt J

更新日期：2017-04-18 00:00:00

abstract：Aim:Six-minute walking test distance (6MWD) and body mass index, obstruction, dyspnea and exercise (BODE) index are measures of functional status in COPD patients, but require space, time and patient's compliance. Exhaled volatile organic compounds (VOCs) analysis via electronic nose is a quick and easy method that has...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Finamore P,Pedone C,Scarlata S,Di Paolo A,Grasso S,Santonico M,Pennazza G,Antonelli Incalzi R

更新日期：2018-05-01 00:00:00

abstract：Background:Patients with diseases linked with smoking, such as COPD, report a health-related stigma on their smoking behavior, which is related to a poorer quality of life and psychological distress. According to patients with COPD, health-care professionals sometimes reinforce the sense of stigma. However, little is k...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Mooren K,van der Linden G,Pool K,Engels Y

更新日期：2019-11-29 00:00:00

abstract：Background:Static hyperinflation is known to be increased during moderate acute exacerbations of chronic obstructive pulmonary disease (COPD) (AECOPD), but few data exist in patients with severe exacerbations of COPD. The role of dynamic hyperinflation during exacerbations is unclear. Methods:In a prospective, observa...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van Geffen WH,Kerstjens HA

更新日期：2018-04-18 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) and heart failure (HF) are both common diseases that coexist frequently. Patients with both diseases have worse stable state health status when compared with patients with one of these diseases. In many outpatient clinics, health status is monitored routinely in C...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Berkhof FF,Metzemaekers L,Uil SM,Kerstjens HA,van den Berg JW

更新日期：2014-09-22 00:00:00

abstract：BACKGROUND:The relationship between prior health care utilization and respiratory medication prescriptions in an unselected population of patients with COPD is not known. METHODS:We determined the prescribed respiratory medications and respiratory and nonrespiratory health care encounters in 523 Veterans with COPD at ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Seaman J,Leonard AC,Panos RJ

更新日期：2010-04-07 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Chronic obstructive pulmonary disease (COPD) is one of the most debilitating somatic diseases, having anxiety and depression frequently as comorbidities. The coping style, the way in which the subject manages to control the difficult and stressful situations of life, can influence its evolutio...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Papava I,Oancea C,Enatescu VR,Bredicean AC,Dehelean L,Romosan RS,Timar B

更新日期：2016-06-20 00:00:00

abstract：Background:COPD is characterized by a persistent inflammatory response, especially against cigarette smoke. COPD patients may develop varying degrees of emphysematous destruction of the lungs. A pathophysiological role for miRNAs in COPD has been suggested in several studies. We examined changes in microRNAs expression...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cazorla-Rivero S,Mura-Escorche G,Gonzalvo-Hernández F,Mayato D,Córdoba-Lanús E,Casanova C

更新日期：2020-10-29 00:00:00

abstract：:Health status questionnaires provide standardized measures of patients' perceptions of the impact of disease on their daily life and well-being. Factors associated with health status were examined in a sample of 58 outpatients with chronic obstructive pulmonary disease (COPD) and co-morbid anxiety and/or depression. A...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hynninen MJ,Pallesen S,Nordhus IH

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Homology is a mathematical concept that can be used to quantify degree of contact. Recently, image processing with the homology method has been proposed. In this study, we used the homology method and computed tomography images to quantify emphysema. METHODS:This study included 112 patients who had undergon...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Nishio M,Nakane K,Tanaka Y

更新日期：2016-09-06 00:00:00

abstract：BACKGROUND:Concerns have been raised that treatment of COPD with inhaled corticosteroids may increase pneumonia risk. Responding to a request from the European Medicines Agency Pharmacovigilance Risk Assessment Committee, a pooled analysis of interventional studies compared pneumonia risk with inhaled budesonide-contai...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hollis S,Jorup C,Lythgoe D,Martensson G,Regnell P,Eckerwall G

更新日期：2017-04-05 00:00:00

abstract：BACKGROUND:Exacerbations of chronic obstructive pulmonary disease (COPD) lead to significant increases in resource utilization and cost to the health care system. COPD patients with chronic bronchitis and a history of exacerbations pose an additional burden to the system. This study examined health care utilization and...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pasquale MK,Sun SX,Song F,Hartnett HJ,Stemkowski SA

更新日期：2012-01-01 00:00:00