Frailty syndrome in ambulatory patients with COPD.

abstract：Background:Few studies have examined changes in the pain experience of patients with COPD and predictors of pain in these patients. Objectives:The objectives of the study were to examine whether distinct groups of COPD patients could be identified based on changes in the occurrence and severity of pain over 12 months ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bentsen SB,Miaskowski C,Cooper BA,Christensen VL,Henriksen AH,Holm AM,Rustøen T

更新日期：2018-03-06 00:00:00

abstract：BACKGROUND:Exacerbations of chronic obstructive pulmonary disease (COPD) lead to significant increases in resource utilization and cost to the health care system. COPD patients with chronic bronchitis and a history of exacerbations pose an additional burden to the system. This study examined health care utilization and...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pasquale MK,Sun SX,Song F,Hartnett HJ,Stemkowski SA

更新日期：2012-01-01 00:00:00

abstract：Background:COPD is considered an independent risk factor for lung cancer. COPD and lung cancer are both very heterogeneous diseases, and the study herein investigates the link between COPD phenotypes and specific histological subtypes of lung cancer. Methods:This case-control study comprised 2,283 patients with newly ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wang W,Xie M,Dou S,Cui L,Zheng C,Xiao W

更新日期：2018-04-13 00:00:00

abstract：Purpose:On March 16, 2020, the Spanish government declared a state of alarm due to the rapid spread of coronavirus disease 2019 (COVID-19). Patients with chronic obstructive pulmonary disease (COPD) were restricted to remain confined at home, and medical visits were cancelled for 3 months. The impact of this lockdown o...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pleguezuelos E,Del Carmen A,Moreno E,Ortega P,Vila X,Ovejero L,Serra-Prat M,Palomera E,Garnacho-Castaño MV,Loeb E,Farago G,Miravitlles M

更新日期：2020-10-23 00:00:00

abstract：Purpose:This study investigated the effect of dual bronchodilation with the long-acting β-receptor agonist/long-acting muscarinic antagonist combination, indacaterol/glycopyrronium (IND/GLY), on nighttime oxygenation, lung function, sleep quality, and symptoms in patients with moderate-to-severe COPD. Patients and met...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lehmann S,Ringbæk T,Løkke A,Grote L,Hedner J,Lindberg E

更新日期：2019-01-09 00:00:00

abstract：:Pulmonary emphysema is characterized by the irreversible loss of pulmonary alveoli. Despite recent advances in the understanding this disease, its treatment remains palliative. In this review, we will successively review the data suggesting (1) that alveolar regeneration systems are functional in the mammalian lung an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Plantier L,Boczkowski J,Crestani B

更新日期：2007-01-01 00:00:00

abstract：:Pulmonary emphysema is usually the result of chronic exposure to cigarette smoke in at risk individuals. To investigate the hypothesis that lung damage in emphysema results from coincident weakening in the structural properties of the tissue and increased mechanical forces--as one explanation of the continued developm...

journal_title：International journal of chronic obstructive pulmonary disease

authors： de Ryk J,Thiesse J,Namati E,McLennan G

更新日期：2007-01-01 00:00:00

abstract：Purpose:Primary care COPD guidelines indicate that COPD patients with asthma characteristics should be treated as having asthma. This study aims to describe the prevalence of asthma characteristics in patients with a pulmonologist-confirmed working diagnosis of COPD or ACO. Patients and Methods:This retrospective cros...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Baron AJ,Flokstra-de Blok BMJ,van Heijst E,Riemersma RA,Sonnenschein-van der Voort AMM,Metting EI,Kocks JWH

更新日期：2020-07-06 00:00:00

abstract：Purpose:To evaluate clinical periodontal status and microbiologic pathogens in patients with chronic obstructive pulmonary disease (COPD) and periodontitis. Patients and Methods:We conducted a case-control study of 60 periodontitis patients with COPD (case group) and 60 periodontitis patients with normal pulmonary fun...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhou X,Wang J,Liu W,Huang X,Song Y,Wang Z,Jia X

更新日期：2020-09-03 00:00:00

abstract：BACKGROUND:The use of inhaled corticosteroids in patients with chronic obstructive pulmonary disease (COPD) has been associated with an increased risk of pneumonia in controlled clinical trials and case-control analyses. OBJECTIVE:Using claims databases as a research model of real-world diagnosis and treatment, to det...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Yawn BP,Li Y,Tian H,Zhang J,Arcona S,Kahler KH

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:To explore the decision-making of general practitioners (GPs) concerning treatment with antibiotics and/or oral corticosteroids and hospitalization for COPD patients with exacerbations. METHODS:Thematic analysis of seven focus groups with 53 GPs from urban and rural areas in Norway, Germany, Wales, Poland, Rus...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Laue J,Melbye H,Halvorsen PA,Andreeva EA,Godycki-Cwirko M,Wollny A,Francis NA,Spigt M,Kung K,Risør MB

更新日期：2016-12-08 00:00:00

abstract：BACKGROUND:Noncommunicable diseases have become a public heath problem in India concomitant with economic development, leading to increases in tobacco consumption, obesity, and changes in diet and lifestyle. Although observation suggests that tobacco consumption is a major risk factor for deaths due to circulatory, pul...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Singh RB,Singh S,Chattopadhya P,Singh K,Singhz V,Kulshrestha SK,Tomar RS,Kumar R,Singh G,Mechirova V,Pella D

更新日期：2007-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD), a respiratory disease characterized by a progressive decline in lung function, is considered to be a leading cause of morbidity and mortality. Long-acting inhaled bronchodilators, such as long-acting β2 agonists (LABAs) or long-acting muscarinic antagonists (LAMAs), are th...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ramadan WH,Kabbara WK,El Khoury GM,Al Assir SA

更新日期：2015-10-30 00:00:00

abstract：INTRODUCTION:End-stage lung disease (ESLD) (predominantly caused by chronic obstructive pulmonary disease and restrictive lung disease) is a significant cause of death. Little is known about community care for people with ESLD especially in the period leading to death. This paper describes demographic characteristics o...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Currow DC,Ward A,Clark K,Burns CM,Abernethy AP

更新日期：2008-01-01 00:00:00

abstract：Introduction:Long-term use of nebulized or oral antibiotics is common in the treatment of cystic fibrosis and non-cystic fibrosis bronchiectasis. To date, however, few studies have focused on the use of nebulized antibiotics in COPD patients. The aims of this study are: to establish whether a combination of nebulized c...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Montón C,Prina E,Pomares X,Cugat JR,Casabella A,Oliva JC,Gallego M,Monsó E

更新日期：2019-10-17 00:00:00

abstract：Background:Previous studies suggest that gender differences exist in COPD diagnosis and symptoms; these differences may be more pronounced in younger adults. Our objective was to explore age-associated gender differences across a range of COPD severities. Materials and methods:A total of 4,484 current and former smoke...

journal_title：International journal of chronic obstructive pulmonary disease

authors： DeMeo DL,Ramagopalan S,Kavati A,Vegesna A,Han MK,Yadao A,Wilcox TK,Make BJ,COPDGene Investigators.

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The diagnosis and assessment of COPD rely mainly on the use of spirometry, which is an effort-dependent test and requires good patient cooperation. Impulse oscillometry (IOS) is a non-volitional method that requires less effort and cooperation and presents advantages for geriatric patients. However, the clin...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liu Z,Lin L,Liu X

更新日期：2017-03-15 00:00:00

abstract：Purpose:The aims of this study were to evaluate dynamic changes in heart size during the respiratory cycle using four-dimensional computed tomography (CT) and to understand the relationship of these changes to airflow limitation in smokers. Materials and methods:A total of 31 smokers, including 13 with COPD, underwent...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xu Y,Yamashiro T,Moriya H,Tsubakimoto M,Tsuchiya N,Nagatani Y,Matsuoka S,Murayama S

更新日期：2017-10-26 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is associated with an increased cardiovascular risk. However, the mechanisms for this association are yet unclear. The aim of this study was to investigate the relationship between brachial intima-media thickness (B-IMT), an independent predictor of cardiovascular...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Urban MH,Eickhoff P,Funk GC,Burghuber OC,Wolzt M,Valipour A

更新日期：2017-01-04 00:00:00

abstract：BACKGROUND:The causal association between depression, anxiety, and health-related quality of life (HRQoL) in chronic obstructive pulmonary disease (COPD) is unclear. We therefore conducted a systematic review of prospective cohort studies that measured depression, anxiety, and HRQoL in COPD. METHODS:Electronic databas...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Blakemore A,Dickens C,Guthrie E,Bower P,Kontopantelis E,Afzal C,Coventry PA

更新日期：2014-05-20 00:00:00

abstract：Purpose:Peripheral blood eosinophilic counts are susceptible to many factors and have variability over time. There are limited studies on association of blood eosinophilia with long-term mortality of chronic obstructive pulmonary disease (COPD) patients and these results remain controversial. Our aims were to explore t...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhang Y,Liang LR,Zhang S,Lu Y,Chen YY,Shi HZ,Lin YX

更新日期：2020-05-19 00:00:00

abstract：:Measurement of inspiratory capacity (IC) as a marker of dynamic lung hyperinflation has been shown to correlate with dyspnea and exercise performance in stable COPD, and is therefore of potential utility in the management of this condition. We have examined whether similar relationships exist during acute exacerbation...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pretto JJ,McMahon MA,Rochford PD,Berlowitz DJ,Jones SM,Brazzale DJ,McDonald CF

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to describe the prevalence of renal and hepatic disease, related laboratory abnormalities, and potentially hepatotoxic and nephrotoxic medication use in a population-based cohort of persons with chronic obstructive pulmonary disease (COPD). METHODS:This was a retrospective case...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Mapel DW,Marton JP

更新日期：2013-01-01 00:00:00

abstract：:TRPM8 plays a key role in COPD. The development of pulmonary hypertension (PH) in COPD adversely affects survival and exercise capacity. Thus, the aim of this study was to evaluate the possible association between single nucleotide polymorphisms (SNPs) in TRPM8 and COPD or PH in COPD among the Chinese Han population. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xiong M,Wang J,Guo M,Zhou Q,Lu W

更新日期：2016-10-14 00:00:00

abstract：BACKGROUND:Polypharmacy of respiratory medications is commonly observed in patients with chronic obstructive pulmonary disease (COPD). The aims of this study were to investigate determinants of polypharmacy and to study the consistency of actual respiratory drug use with current Global Initiative for Chronic Obstructiv...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Franssen FM,Spruit MA,Wouters EF

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Whereas the epidemiological association between lung cancer and chronic obstructive pulmonary disease (COPD), a chronic inflammatory respiratory disease, is well known, limited studies have examined the association between lung cancer and non-cystic fibrosis bronchiectasis, a representative chronic airway in...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim YW,Jin KN,Heo EY,Park SS,Chung HS,Kim DK

更新日期：2015-05-04 00:00:00

abstract：BACKGROUND:Despite the availability of national and international guidelines, evidence suggests that chronic obstructive pulmonary disease (COPD) treatment is not always prescribed according to recommendations. This study evaluated the current management of patients with COPD using a large UK primary-care database. ME...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Price D,West D,Brusselle G,Gruffydd-Jones K,Jones R,Miravitlles M,Rossi A,Hutton C,Ashton VL,Stewart R,Bichel K

更新日期：2014-08-27 00:00:00

abstract：:Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) released an updated document in 2017 that excluded the spirometric parameter in the classification of patients. The validity of this new classification system in predicting mortality and respiratory hospitalization is still uncertain. Method...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lee SJ,Yun SS,Ju S,You JW,Cho YJ,Jeong YY,Kim JY,Kim HC,Lee JD

更新日期：2019-04-29 00:00:00

abstract：INTRODUCTION:Randomized interventional trials generally recruit highly selected patients. In contrast, long-term, noninterventional studies can reflect standard of care of real-life populations. DACCORD (Die ambulante Versorgung mit langwirksamen Bronchodilatatoren: COPD-Register in Deutschland [Outpatient Care With Lo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Buhl R,Criée CP,Kardos P,Vogelmeier C,Lossi N,Mailänder C,Worth H

更新日期：2016-07-20 00:00:00

abstract：Aim:The aim of the current study was to assess the serum levels of trace minerals/heavy metals in COPD patients with and without pulmonary hypertension (PH) and to investigate their correlations to demographic, clinical, and biochemical variables. Materials and methods:This cross-sectional study was performed in Van Y...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Asker S,Asker M,Yeltekin AC,Aslan M,Ozbay B,Demir H,Turan H

更新日期：2018-05-31 00:00:00