Lung function and long-term safety of tiotropium/olodaterol in East Asian patients with chronic obstructive pulmonary disease.

abstract：:Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease of the lung caused primarily by exposure to cigarette smoke. Clinically, it presents with progressive cough, sputum production, dyspnea, reduced exercise capacity, and diminished quality of life. Physiologically, it is characterized by...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sharafkhaneh A,Mattewal AS,Abraham VM,Dronavalli G,Hanania NA

更新日期：2010-10-05 00:00:00

abstract：INTRODUCTION:End-stage lung disease (ESLD) (predominantly caused by chronic obstructive pulmonary disease and restrictive lung disease) is a significant cause of death. Little is known about community care for people with ESLD especially in the period leading to death. This paper describes demographic characteristics o...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Currow DC,Ward A,Clark K,Burns CM,Abernethy AP

更新日期：2008-01-01 00:00:00

abstract：Background:Static hyperinflation is known to be increased during moderate acute exacerbations of chronic obstructive pulmonary disease (COPD) (AECOPD), but few data exist in patients with severe exacerbations of COPD. The role of dynamic hyperinflation during exacerbations is unclear. Methods:In a prospective, observa...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van Geffen WH,Kerstjens HA

更新日期：2018-04-18 00:00:00

abstract：OBJECTIVES:To explore the mediating role of protein interleukin-6 (IL-6) on the relationship between forced expiratory volume in 1 second (FEV1) and 6-minute walk distance (6MWD) and, further, to determine whether status variables (such as age, sex, and body mass index [BMI]) operate as moderators of this mediation rel...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Baldi S,Jose PE,Bruschi C,Pinna GD,Maestri R,Rezzani A,Bellinzona E,Fracchia C,Dacosto E,Crotti P,Montemartini S

更新日期：2014-10-07 00:00:00

abstract：:Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) released an updated document in 2017 that excluded the spirometric parameter in the classification of patients. The validity of this new classification system in predicting mortality and respiratory hospitalization is still uncertain. Method...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lee SJ,Yun SS,Ju S,You JW,Cho YJ,Jeong YY,Kim JY,Kim HC,Lee JD

更新日期：2019-04-29 00:00:00

abstract：BACKGROUND:The clinical efficacy and safety of a mometasone furoate/formoterol fumarate (MF/F) fixed-dose combination formulation administered via a metered-dose inhaler was investigated in patients with moderate to very severe chronic obstructive pulmonary disease (COPD). METHODS:Two 52-week, multicenter, double-blin...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tashkin DP,Doherty DE,Kerwin E,Matiz-Bueno CE,Knorr B,Shekar T,Gates D,Staudinger H

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:With the growing burden of COPD and associated morbidity and mortality, a need for self-management has been identified. The Self-management Programme of Activity, Coping and Education for Chronic Obstructive Pulmonary Disease (SPACE for COPD) manual was developed to support self-management in COPD patients. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Blackmore C,Johnson-Warrington VL,Williams JE,Apps LD,Young HM,Bourne C,Singh SJ

更新日期：2017-06-07 00:00:00

abstract：BACKGROUND:In addition to smoking, acute exacerbations are considered to be a contributing factor to progression of chronic obstructive pulmonary disease (COPD). However, these findings come from studies including active smokers, while results in ex-smokers are scarce and contradictory. The purpose of this study was to...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Dreyse J,Díaz O,Repetto PB,Morales A,Saldías F,Lisboa C

更新日期：2015-03-10 00:00:00

abstract：BACKGROUND:The chronic obstructive pulmonary disease (COPD) assessment test (CAT) is a short questionnaire that has facilitated health status measurements in subjects with COPD. However, it remains controversial as to whether the CAT can be used as a suitable substitute for the St George's Respiratory Questionnaire (SG...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Morishita-Katsu M,Nishimura K,Taniguchi H,Kimura T,Kondoh Y,Kataoka K,Ogawa T,Watanabe F,Arizono S,Nishiyama O,Nakayasu K,Imaizumi K,Hasegawa Y

更新日期：2016-07-07 00:00:00

abstract：Background:Telerehabilitation (TR) aimed at patients with COPD has shown promising effects on symptoms, physical function, and quality of life, but little research has been conducted to understand the impact of implementation on frontline health professionals. Therefore, the aim of this study was to examine the barrier...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Damhus CS,Emme C,Hansen H

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:Assessment of dyspnea in COPD patients relies in clinical practice on the modified Medical Research Council (mMRC) scale, whereas the Baseline Dyspnea Index (BDI) is mainly used in clinical trials. Little is known on the correspondence between the two methods. METHODS:Cross-sectional analysis was carried ou...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Perez T,Burgel PR,Paillasseur JL,Caillaud D,Deslée G,Chanez P,Roche N,INITIATIVES BPCO Scientific Committee.

更新日期：2015-08-18 00:00:00

abstract：INTRODUCTION:Early palliative care is not a common practice for patients with COPD. Important barriers are the identification of patients for palliative care and the organization of such care in this patient group. OBJECTIVE:Pulmonologists have a central role in providing good quality palliative care for patients with...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Duenk RG,Verhagen C,Dekhuijzen P,Vissers K,Engels Y,Heijdra Y

更新日期：2017-01-17 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a debilitating disease characterized by inflammation-induced airflow limitation and parenchymal destruction. In addition to pulmonary manifestations, patients with COPD develop systemic problems, including skeletal muscle and other organ-specific dysfunctions, nutritiona...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim HC,Mofarrahi M,Hussain SN

更新日期：2008-01-01 00:00:00

abstract：:Pulmonary hypertension (PH) is the hemodynamic manifestation of various pathological processes that result in elevated pulmonary artery pressures (PAP). The National Institutes of Health Registry defined pulmonary arterial hypertension as the mean PAP of more than 25 mm Hg with a pulmonary capillary wedge pressure or ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jyothula S,Safdar Z

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Plasminogen activator inhibitor-1 (PAI-1), a major inhibitor of fibrinolysis, is associated with thrombosis, obesity, insulin resistance, dyslipidemia, and premature aging, which all are coexisting conditions of chronic obstructive pulmonary disease (COPD). The role of PAI-1 in COPD with respect to metabol...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Waschki B,Watz H,Holz O,Magnussen H,Olejnicka B,Welte T,Rabe KF,Janciauskiene S

更新日期：2017-03-22 00:00:00

abstract：Objective:Our aim was to assess the impact of comorbidities on existing COPD prognosis scores. Patients and methods:A total of 543 patients with COPD (FEV1 <80% and FEV1/FVC <70%) were included between January 2003 and January 2004. Patients were stable for at least 6 weeks before inclusion and were followed for 5 yea...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Aramburu A,Arostegui I,Moraza J,Barrio I,Aburto M,García-Loizaga A,Uranga A,Zabala T,Quintana JM,Esteban C

更新日期：2019-03-07 00:00:00

abstract：Rationale:Individual socioeconomic status has been shown to influence the outcomes of patients with chronic obstructive pulmonary disease (COPD). However, contextual factors may also play a role. The objective of this study is to evaluate the association between neighborhood socioeconomic disadvantage measured by the a...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Galiatsatos P,Woo H,Paulin LM,Kind A,Putcha N,Gassett AJ,Cooper CB,Dransfield MT,Parekh TM,Oates GR,Barr RG,Comellas AP,Han MK,Peters SP,Krishnan JA,Labaki WW,McCormack MC,Kaufman JD,Hansel NN

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Glycopyrronium is a once-daily (od) long-acting muscarinic antagonist for the maintenance treatment of chronic obstructive pulmonary disease (COPD). The GLOW7 study evaluated the efficacy and safety of od glycopyrronium 50 μg in predominantly Chinese patients with moderate-to-severe COPD. METHODS:In this 26...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wang C,Sun T,Huang Y,Humphries M,Bai L,Li L,Wang Q,Kho P,Firth R,D'Andrea P

更新日期：2015-01-05 00:00:00

abstract：BACKGROUND:Although chronic obstructive pulmonary disease (COPD) is closely associated with gastroesophageal reflux disease (GERD), the clinical significance of laryngopharyngeal reflux (LPR) is not fully understood in COPD. METHODS:Prospective cohorts were established among 118 patients with COPD from March 2013 to J...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jung YH,Lee DY,Kim DW,Park SS,Heo EY,Chung HS,Kim DK

更新日期：2015-07-15 00:00:00

abstract：Background:Patients with chronic obstructive pulmonary disease (COPD) and cardiovascular comorbidities may have an increased risk of medication-related cardiac arrhythmias. We therefore performed an analysis of Holter electrocardiogram (ECG) data from two large, long-term, controlled clinical COPD trials to investigate...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Andreas S,Bothner U,de la Hoz A,Kloer I,Trampisch M,Alter P

更新日期：2020-08-10 00:00:00

abstract：:Visual and auditory analysis of respiratory sound signals promises improved detection of certain types of lung diseases. LabVIEW software was used to design a system that monitors the respiratory activity of the patient. The program developed calculates the respiratory rate, displays the time expanded waveform of the ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sahgal N

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:It has been scientifically proven that pulmonary rehabilitation improves exercise tolerance and facilitates the carrying out of daily physical activities. To optimize the physical and physiological benefits, it is necessary to individualize the training intensity for each patient. The aim of this study is to...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Fabre C,Chehere B,Bart F,Mucci P,Wallaert B,Grosbois JM

更新日期：2017-05-16 00:00:00

abstract：Purpose:Waterpipe (WP) use has become a global trend in young populations. However, there are few well-controlled studies focusing specifically on the chronic effects of exclusive WP use on young adults' respiratory health. We sought to compare in young adults the burden of respiratory symptoms in regular WP smokers (W...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hawari FI,Obeidat NA,Abu Alhalawa M,Al-Busaidi Z,Amara B,Baddar S,Elhabiby M,Elkholy H

更新日期：2019-08-13 00:00:00

abstract：BACKGROUND:COPD is a major cause of death and morbidity worldwide, and is characterized by persistent airflow obstruction. The evaluation of obstruction is critically dependent on sensitive methods for lung-function testing. A wide body of knowledge has been accumulated in recent years showing that these methods have b...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lopes AJ,de Melo PL

更新日期：2016-07-11 00:00:00

abstract：PURPOSE:Endobronchial valve (EBV) therapy is increasingly being seen as a therapeutic option for advanced emphysema, but its clinical utility in Asian populations, who may have different phenotypes to other ethnic populations, has not been assessed. PATIENTS AND METHODS:This prospective open-label single-arm clinical ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Park TS,Hong Y,Lee JS,Oh SY,Lee SM,Kim N,Seo JB,Oh YM,Lee SD,Lee SW

更新日期：2015-07-29 00:00:00

abstract：Background:Frailty can inform management approaches for individuals with COPD. However, inpatient measures of frailty are seldom employed because they are time-consuming or inapplicable for bed-bound patients. We investigated the feasibility and potential of an innovative sensor-based upper-extremity function (UEF) tes...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ehsani H,Mohler MJ,Golden T,Toosizadeh N

更新日期：2018-12-18 00:00:00

abstract：INTRODUCTION:Randomized interventional trials generally recruit highly selected patients. In contrast, long-term, noninterventional studies can reflect standard of care of real-life populations. DACCORD (Die ambulante Versorgung mit langwirksamen Bronchodilatatoren: COPD-Register in Deutschland [Outpatient Care With Lo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Buhl R,Criée CP,Kardos P,Vogelmeier C,Lossi N,Mailänder C,Worth H

更新日期：2016-07-20 00:00:00

abstract：:Chronic bronchitis is a relatively common entity among patients with underlying chronic obstructive lung disease. Typical treatment includes pulmonary hygiene, bronchodilators, and antimicrobial therapy. In recent years, the duration of antimicrobial therapy in acute exacerbations of COPD has become shorter and shorte...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Milstone AP

更新日期：2008-01-01 00:00:00

abstract：Background:Health effects of electronic cigarette (EC) use in patients with chronic obstructive pulmonary disease (COPD) are largely unexplored. Aim:We present findings from a long-term prospective assessment of respiratory parameters in a cohort of COPD patients who ceased or substantially reduced conventional cigare...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Polosa R,Morjaria JB,Prosperini U,Russo C,Pennisi A,Puleo R,Caruso M,Caponnetto P

更新日期：2018-08-22 00:00:00

abstract：BACKGROUND:In addition to lung involvement, several other diseases and syndromes coexist in patients with chronic obstructive pulmonary disease (COPD). Our purpose was to investigate the prevalence of idiopathic arterial hypertension (IAH), ischemic heart disease, heart failure, peripheral vascular disease (PVD), diabe...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Camiciottoli G,Bigazzi F,Magni C,Bonti V,Diciotti S,Bartolucci M,Mascalchi M,Pistolesi M

更新日期：2016-09-14 00:00:00