Use of azithromycin in the treatment of acute exacerbations of COPD.

abstract：BACKGROUND:The aim of this study was to determine whether long-term intermittent azithromycin therapy reduces the frequency of exacerbation in severe chronic obstructive pulmonary disease (COPD). METHODS:We retrospectively investigated the clinical benefits of long-term azithromycin (500 mg orally three times per week...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pomares X,Montón C,Espasa M,Casabon J,Monsó E,Gallego M

更新日期：2011-01-01 00:00:00

abstract：Background:Despite chronic obstructive pulmonary disease (COPD) being the commonest non-communicable disease in Nepal, there is limited research evidence estimating the spirometry-based burden of COPD. This study aims to estimate the prevalence of COPD and its correlates through a community-based survey in Pokhara Metr...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Adhikari TB,Acharya P,Högman M,Neupane D,Karki A,Drews A,Cooper BG,Sigsgaard T,Kallestrup P

更新日期：2020-09-29 00:00:00

abstract：:Abstract: Static lung hyperinflation has important clinical consequences in patients with chronic obstructive pulmonary disease (COPD). Given that most of these patients have respiratory and peripheral muscle weakness, dyspnea and functional exercise capacity may improve as a result of inspiratory muscle training (IMT...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Shahin B,Germain M,Kazem A,Annat G

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The diagnosis and assessment of COPD rely mainly on the use of spirometry, which is an effort-dependent test and requires good patient cooperation. Impulse oscillometry (IOS) is a non-volitional method that requires less effort and cooperation and presents advantages for geriatric patients. However, the clin...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liu Z,Lin L,Liu X

更新日期：2017-03-15 00:00:00

abstract：BACKGROUND:Smoking is a major risk factor for chronic obstructive pulmonary disease (COPD); however, the similarities and differences in clinical presentation between smokers and nonsmokers are not fully described in patients with COPD. This study was designed to address this issue in a general teaching hospital in the...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhang J,Lin XF,Bai CX

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Previous studies have documented that C-reactive protein (CRP) levels are increased in stable COPD patients. However, most studies have also shown that higher CRP levels are observed in patients with comorbidities like diabetes mellitus and cardiovascular disease. We aimed to investigate if CRP levels are in...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Silva DR,Gazzana MB,Knorst MM

更新日期：2015-08-31 00:00:00

abstract：BACKGROUND AND AIM:Patients with advanced chronic obstructive pulmonary disease (COPD) have poor quality of life. The aim of this study was to assess the effects of proactive palliative care on the well-being of these patients. TRIAL REGISTRATION:This trial is registered with the Netherlands Trial Register, NTR4037. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Duenk RG,Verhagen C,Bronkhorst EM,van Mierlo P,Broeders M,Collard SM,Dekhuijzen P,Vissers K,Heijdra Y,Engels Y

更新日期：2017-09-28 00:00:00

abstract：BACKGROUND:The syndrome of combined pulmonary fibrosis and emphysema (CPFE) is a recently described entity associating upper-lobe emphysema and lower-lobe fibrosis. We sought to evaluate differences in pulmonary function between CPFE patients with and without airflow obstruction. SUBJECTS AND METHODS:Thirty-one CPFE p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kitaguchi Y,Fujimoto K,Hanaoka M,Honda T,Hotta J,Hirayama J

更新日期：2014-07-29 00:00:00

abstract：INTRODUCTION:Pulmonary emphysema causes several electrocardiogram changes, and one of the most common and well known is on the frontal P-wave axis. P-axis verticalization (P-axis > 60°) serves as a quasidiagnostic indicator of emphysema. The correlation of P-axis verticalization with the radiological severity of emphys...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chhabra L,Chaubey VK,Kothagundla C,Bajaj R,Kaul S,Spodick DH

更新日期：2013-01-01 00:00:00

abstract：:Visual and auditory analysis of respiratory sound signals promises improved detection of certain types of lung diseases. LabVIEW software was used to design a system that monitors the respiratory activity of the patient. The program developed calculates the respiratory rate, displays the time expanded waveform of the ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sahgal N

更新日期：2011-01-01 00:00:00

abstract：Background:Domiciliary noninvasive ventilation (NIV) use in stable hypercarbic COPD is becoming increasingly widespread. However, treatment compliance criteria and factors related to compliance remain to be defined. Methods:This research was designed as a prospective, cross-sectional, multicenter real-life study. Chro...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Yazar EE,Özlü T,Sarıaydın M,Taylan M,Ekici A,Aydın D,Coşgun İG,Durmuş Koçak N

更新日期：2018-08-10 00:00:00

abstract：:In this review we consider the therapeutic potential of targeting Akt for the treatment of COPD. Akt is a serine/threonine protein kinase that functions as a signaling intermediate linked to multiple signaling programs involved in survival, inflammation, and growth. Akt is closely associated with key membrane-bound re...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bozinovski S,Vlahos R,Hansen M,Liu K,Anderson GP

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Recent studies that assessed the relevance of the blood eosinophil count as a biomarker in patients with COPD may have overestimated it because they included patients with asthma-COPD overlap syndrome (ACOS). We investigated the clinical implications of the blood eosinophil count in patients with non-ACOS CO...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Song JH,Lee CH,Kim JW,Lee WY,Jung JY,Park JH,Jung KS,Yoo KH,Park YB,Kim DK

更新日期：2017-08-17 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a debilitating disease characterized by inflammation-induced airflow limitation and parenchymal destruction. In addition to pulmonary manifestations, patients with COPD develop systemic problems, including skeletal muscle and other organ-specific dysfunctions, nutritiona...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim HC,Mofarrahi M,Hussain SN

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The use of chlorofluorocarbons (CFCs) has contributed to the depletion of the stratospheric ozone layer resulting in serious health concerns. Ipratropium bromide/salbutamol sulphate CFC-pressurized metered-dose inhalers (IB/SAL-CFC pMDI) have been in widespread use for many years without any apparent ill con...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bhattacharya A,Bhargava S,Singh V,Talwar D,Whig J,Rebello J,Purandare S,Gogtay J

更新日期：2016-06-30 00:00:00

abstract：:A number of excellent intervention studies related to clinical and psychosocial aspects of chronic obstructive pulmonary disease (COPD) have been undertaken in the recent past. A range of outcomes have been examined including pulmonary function, health care use, quality of life, anxiety and depression, ambulation, exe...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Clark NM,Dodge JA,Partridge MR,Martinez FJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Homology is a mathematical concept that can be used to quantify degree of contact. Recently, image processing with the homology method has been proposed. In this study, we used the homology method and computed tomography images to quantify emphysema. METHODS:This study included 112 patients who had undergon...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Nishio M,Nakane K,Tanaka Y

更新日期：2016-09-06 00:00:00

abstract：Aim:The aim of the current study was to assess the serum levels of trace minerals/heavy metals in COPD patients with and without pulmonary hypertension (PH) and to investigate their correlations to demographic, clinical, and biochemical variables. Materials and methods:This cross-sectional study was performed in Van Y...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Asker S,Asker M,Yeltekin AC,Aslan M,Ozbay B,Demir H,Turan H

更新日期：2018-05-31 00:00:00

abstract：Background:Previous studies suggest that gender differences exist in COPD diagnosis and symptoms; these differences may be more pronounced in younger adults. Our objective was to explore age-associated gender differences across a range of COPD severities. Materials and methods:A total of 4,484 current and former smoke...

journal_title：International journal of chronic obstructive pulmonary disease

authors： DeMeo DL,Ramagopalan S,Kavati A,Vegesna A,Han MK,Yadao A,Wilcox TK,Make BJ,COPDGene Investigators.

更新日期：2018-10-01 00:00:00

abstract：Purpose:Education on the self-management of COPD has been shown to improve patients' quality of life and reduce hospital admissions. This study aimed to assess the feasibility of a pilot, pragmatic COPD Chronic Care (CCC) education program led by registered respiratory therapists and determine the CCC's impact on hospi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Collinsworth AW,Brown RM,James CS,Stanford RH,Alemayehu D,Priest EL

更新日期：2018-04-24 00:00:00

abstract：Background:Frailty can inform management approaches for individuals with COPD. However, inpatient measures of frailty are seldom employed because they are time-consuming or inapplicable for bed-bound patients. We investigated the feasibility and potential of an innovative sensor-based upper-extremity function (UEF) tes...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ehsani H,Mohler MJ,Golden T,Toosizadeh N

更新日期：2018-12-18 00:00:00

abstract：PURPOSE:To explore the decision-making of general practitioners (GPs) concerning treatment with antibiotics and/or oral corticosteroids and hospitalization for COPD patients with exacerbations. METHODS:Thematic analysis of seven focus groups with 53 GPs from urban and rural areas in Norway, Germany, Wales, Poland, Rus...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Laue J,Melbye H,Halvorsen PA,Andreeva EA,Godycki-Cwirko M,Wollny A,Francis NA,Spigt M,Kung K,Risør MB

更新日期：2016-12-08 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disease with an increasing prevalence worldwide. Its potential consequences, including reduced function and reduced social participation, are likely to be associated with decreased health-related quality of life (HRQoL). However, illness percept...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bonsaksen T,Haukeland-Parker S,Lerdal A,Fagermoen MS

更新日期：2014-01-01 00:00:00

abstract：Introduction:Long-term oxygen therapy (LTOT) improves survival and may reduce hospital admissions in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia, but the impact of daily duration of LTOT on hospitalization rate is unknown. We aimed to estimate the association between the daily durati...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sundh J,Ahmadi Z,Ekström M

更新日期：2018-08-28 00:00:00

abstract：OBJECTIVES:To explore the mediating role of protein interleukin-6 (IL-6) on the relationship between forced expiratory volume in 1 second (FEV1) and 6-minute walk distance (6MWD) and, further, to determine whether status variables (such as age, sex, and body mass index [BMI]) operate as moderators of this mediation rel...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Baldi S,Jose PE,Bruschi C,Pinna GD,Maestri R,Rezzani A,Bellinzona E,Fracchia C,Dacosto E,Crotti P,Montemartini S

更新日期：2014-10-07 00:00:00

abstract：Purpose:The forced mid-expiratory flow (FEF25-75%) value is a potentially sensitive marker of obstructive peripheral airflow. We aimed to assess whether FEF25-75% can be an early predictor of chronic obstructive pulmonary disease (COPD). Patients and Methods:Between July 1, 2007 and June 31, 2009, we identified 3624 p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kwon DS,Choi YJ,Kim TH,Byun MK,Cho JH,Kim HJ,Park HJ

更新日期：2020-11-12 00:00:00

abstract：BACKGROUND:This study was conducted in order to investigate the differences in the respiratory physiology of patients with chronic obstructive pulmonary disease (COPD), asthma-COPD overlap syndrome (ACOS), and asthma with airflow limitation (asthma FL(+)). METHODS:The medical records for a series of all stable patient...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kitaguchi Y,Yasuo M,Hanaoka M

更新日期：2016-05-09 00:00:00

abstract：:Impaired physical performance is common in chronic obstructive pulmonary disease (COPD), but its assessment can be difficult in routine clinical practice. We compared the timed up and go (TUG) test and other easily applied assessments of physical performance with the 6-minute walk distance (6MWD). In a longitudinal st...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Albarrati AM,Gale NS,Enright S,Munnery MM,Cockcroft JR,Shale DJ

更新日期：2016-08-02 00:00:00

abstract：Background:The use of inhaled corticosteroid (ICS) in patients with chronic obstructive pulmonary disease (COPD) decreases the frequency of COPD exacerbations. Recently, pneumonia was reported as a complication of ICS in patients with COPD. However, there have been few reports concerning the relationship between ICS an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hirano R,Fujita M,Matsumoto T,On R,Watanabe K

更新日期：2018-10-23 00:00:00

abstract：Background:In COPD disturbed sleep is related to exacerbation frequency, poor quality of life, and early mortality. We developed the Manchester Respiratory-related Sleep Symptoms scale (MaRSS) to assess sleep-time symptoms in COPD. Methods:Focus groups including COPD and age-matched controls were used to develop an it...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Khan N,Vestbo J,Garrow A,Karur P,Kolsum U,Tyson S,Singh D,Yorke J

更新日期：2018-11-29 00:00:00