Daily duration of long-term oxygen therapy and risk of hospitalization in oxygen-dependent COPD patients.

Abstract:

Introduction:Long-term oxygen therapy (LTOT) improves survival and may reduce hospital admissions in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia, but the impact of daily duration of LTOT on hospitalization rate is unknown. We aimed to estimate the association between the daily duration of LTOT (24 vs 15 h/d) and hospital admissions in patients with LTOT due to COPD. Materials and methods:A population-based, cohort study included patients who started LTOT due to COPD between October 1, 2005 and June 30, 2009 in the Swedish national register for respiratory failure (Swedevox). Time to first hospitalization from all causes and from respiratory or nonrespiratory disease, using the National Patient Registry, was analyzed using Fine-Gray regression, adjusting for potential confounders. Results:A total of 2,249 patients with COPD (59% women) were included. LTOT 24 h/d was prescribed to 539 (24%) and LTOT 15-16 h/d to 1,231 (55%) patients. During a median follow-up of 1.1 years (interquartile range, 0.6-2.1 years), 1,702 (76%) patients were hospitalized. No patient was lost to follow-up. The adjusted rate of all-cause hospitalization was similar between LTOT 24 and 15-16 h/d (subdistribution hazard ratio [SHR] 0.96; [95% CI] 0.84-1.08), as was cause-specific hospitalizations analyzed for respiratory disease (SHR: 1.00; 95% CI: 0.86-1.17) and nonrespiratory disease (SHR: 0.92; 95% CI: 0.75-1.14). Conclusion:LTOT prescribed for 24 h/d was not associated with decreased hospitalization rates compared with LTOT for 15-16 h/d in patients with oxygen-dependent COPD. The results should be validated in a randomized controlled trial.

authors

Sundh J,Ahmadi Z,Ekström M

doi

10.2147/COPD.S167523

subject

Has Abstract

pub_date

2018-08-28 00:00:00

pages

2623-2628

eissn

1176-9106

issn

1178-2005

pii

copd-13-2623

journal_volume

13

pub_type

杂志文章
  • Safety and effectiveness of the high-frequency chest wall oscillation vs intrapulmonary percussive ventilation in patients with severe COPD.

    abstract:Purpose:Chest physiotherapy is an important tool in the treatment of COPD. Intrapulmonary percussive ventilation (IPV) and high-frequency chest wall oscillation (HFCWO) are techniques designed to create a global percussion of the lung which removes secretions and probably clears the peripheral bronchial tree. We tested...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,随机对照试验

    doi:10.2147/COPD.S145440

    authors: Nicolini A,Grecchi B,Ferrari-Bravo M,Barlascini C

    更新日期:2018-02-16 00:00:00

  • Whole-body vibration training - better care for COPD patients: a systematic review and meta-analysis.

    abstract:Purpose:Whole-body vibrating training (WBVT) is a modality aiming to improve neuromuscular performance of patients with COPD. However, a consensus on the effects of WBVT has not been reached. We aimed to clarify the effects of WBVT on functional exercise capacity, pulmonary function, and quality of life in COPD patient...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,meta分析

    doi:10.2147/COPD.S176229

    authors: Zhou J,Pang L,Chen N,Wang Z,Wang C,Hai Y,Lyu M,Lai H,Lin F

    更新日期:2018-10-10 00:00:00

  • How do general practitioners implement decision-making regarding COPD patients with exacerbations? An international focus group study.

    abstract:PURPOSE:To explore the decision-making of general practitioners (GPs) concerning treatment with antibiotics and/or oral corticosteroids and hospitalization for COPD patients with exacerbations. METHODS:Thematic analysis of seven focus groups with 53 GPs from urban and rural areas in Norway, Germany, Wales, Poland, Rus...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究

    doi:10.2147/COPD.S118856

    authors: Laue J,Melbye H,Halvorsen PA,Andreeva EA,Godycki-Cwirko M,Wollny A,Francis NA,Spigt M,Kung K,Risør MB

    更新日期:2016-12-08 00:00:00

  • COPD in primary lung cancer patients: prevalence and mortality.

    abstract:BACKGROUND:Previous studies have relied on international spirometry criteria to diagnose COPD in patients with lung cancer without considering the effect lung cancer might have on spirometric results. The aim of this study was to examine the prevalence of COPD and emphysema at the time of primary lung cancer diagnosis ...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S101183

    authors: Ytterstad E,Moe PC,Hjalmarsen A

    更新日期:2016-03-23 00:00:00

  • Long-term azithromycin therapy in patients with severe COPD and repeated exacerbations.

    abstract:BACKGROUND:The aim of this study was to determine whether long-term intermittent azithromycin therapy reduces the frequency of exacerbation in severe chronic obstructive pulmonary disease (COPD). METHODS:We retrospectively investigated the clinical benefits of long-term azithromycin (500 mg orally three times per week...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S23655

    authors: Pomares X,Montón C,Espasa M,Casabon J,Monsó E,Gallego M

    更新日期:2011-01-01 00:00:00

  • Static and dynamic hyperinflation during severe acute exacerbations of chronic obstructive pulmonary disease.

    abstract:Background:Static hyperinflation is known to be increased during moderate acute exacerbations of chronic obstructive pulmonary disease (COPD) (AECOPD), but few data exist in patients with severe exacerbations of COPD. The role of dynamic hyperinflation during exacerbations is unclear. Methods:In a prospective, observa...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S154878

    authors: van Geffen WH,Kerstjens HA

    更新日期:2018-04-18 00:00:00

  • Patient preferences in severe COPD and asthma: a comprehensive literature review.

    abstract:BACKGROUND:Management of chronic incurable diseases such as chronic obstructive pulmonary disease (COPD) and asthma is difficult. Incorporation of patient preferences is widely encouraged. PURPOSE:To summarize original research articles determining patient preference in moderate-to-severe disease. METHODS:Acceptable ...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,评审

    doi:10.2147/COPD.S82179

    authors: Bereza BG,Troelsgaard Nielsen A,Valgardsson S,Hemels ME,Einarson TR

    更新日期:2015-04-08 00:00:00

  • Impact of comorbid conditions in COPD patients on health care resource utilization and costs in a predominantly Medicare population.

    abstract:BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) often have multiple underlying comorbidities, which may lead to increased health care resource utilization (HCRU) and costs. OBJECTIVE:To describe the comorbidity profiles of COPD patients and examine the associations between the presence of comorbi...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S112256

    authors: Schwab P,Dhamane AD,Hopson SD,Moretz C,Annavarapu S,Burslem K,Renda A,Kaila S

    更新日期:2017-02-23 00:00:00

  • Inhaled corticosteroid use in patients with chronic obstructive pulmonary disease and the risk of pneumonia: a retrospective claims data analysis.

    abstract:BACKGROUND:The use of inhaled corticosteroids in patients with chronic obstructive pulmonary disease (COPD) has been associated with an increased risk of pneumonia in controlled clinical trials and case-control analyses. OBJECTIVE:Using claims databases as a research model of real-world diagnosis and treatment, to det...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S42366

    authors: Yawn BP,Li Y,Tian H,Zhang J,Arcona S,Kahler KH

    更新日期:2013-01-01 00:00:00

  • Soluble urokinase-type plasminogen activator receptor is a novel biomarker predicting acute exacerbation in COPD.

    abstract:BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory condition, and progresses with acute exacerbations. (AE). During AE, levels of acute phase reactants such as C-reactive protein (CRP) and inflammatory cells in the circulation increase. Soluble urokinase-type plasminogen activator recepto...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S77654

    authors: Gumus A,Altintas N,Cinarka H,Kirbas A,Hazıroglu M,Karatas M,Sahin U

    更新日期:2015-02-13 00:00:00

  • Impact of selective and nonselective beta-blockers on the risk of severe exacerbations in patients with COPD.

    abstract:BACKGROUND:There is conflicting information regarding the effects of selective and nonselective beta-blocker treatment in patients with COPD. PARTICIPANTS AND METHODS:This nested case-control study used the Taiwan National Health Insurance Research Database. We included COPD patients who used inhalation steroid and be...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S145913

    authors: Huang YL,Lai CC,Wang YH,Wang CY,Wang JY,Wang HC,Yu CJ,Chen L

    更新日期:2017-10-11 00:00:00

  • Prevalence of comorbidities according to predominant phenotype and severity of chronic obstructive pulmonary disease.

    abstract:BACKGROUND:In addition to lung involvement, several other diseases and syndromes coexist in patients with chronic obstructive pulmonary disease (COPD). Our purpose was to investigate the prevalence of idiopathic arterial hypertension (IAH), ischemic heart disease, heart failure, peripheral vascular disease (PVD), diabe...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S111724

    authors: Camiciottoli G,Bigazzi F,Magni C,Bonti V,Diciotti S,Bartolucci M,Mascalchi M,Pistolesi M

    更新日期:2016-09-14 00:00:00

  • Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function.

    abstract:INTRODUCTION:Plasminogen activator inhibitor-1 (PAI-1), a major inhibitor of fibrinolysis, is associated with thrombosis, obesity, insulin resistance, dyslipidemia, and premature aging, which all are coexisting conditions of chronic obstructive pulmonary disease (COPD). The role of PAI-1 in COPD with respect to metabol...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S128689

    authors: Waschki B,Watz H,Holz O,Magnussen H,Olejnicka B,Welte T,Rabe KF,Janciauskiene S

    更新日期:2017-03-22 00:00:00

  • Platelet-lymphocyte ratios: a potential marker for pulmonary tuberculosis diagnosis in COPD patients.

    abstract:BACKGROUND:In recent decades, morbidity and mortality have been found to be significantly increased in patients with chronic obstructive pulmonary disease (COPD) complicated with pulmonary tuberculosis (PTB). Platelet-lymphocyte ratio (PLR) is an indicator for inflammatory diseases. This study aims to investigate wheth...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S111254

    authors: Chen G,Wu C,Luo Z,Teng Y,Mao S

    更新日期:2016-11-03 00:00:00

  • Stress distribution in a three dimensional, geometric alveolar sac under normal and emphysematous conditions.

    abstract::Pulmonary emphysema is usually the result of chronic exposure to cigarette smoke in at risk individuals. To investigate the hypothesis that lung damage in emphysema results from coincident weakening in the structural properties of the tissue and increased mechanical forces--as one explanation of the continued developm...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/copd.2007.2.1.81

    authors: de Ryk J,Thiesse J,Namati E,McLennan G

    更新日期:2007-01-01 00:00:00

  • Determinants of polypharmacy and compliance with GOLD guidelines in patients with chronic obstructive pulmonary disease.

    abstract:BACKGROUND:Polypharmacy of respiratory medications is commonly observed in patients with chronic obstructive pulmonary disease (COPD). The aims of this study were to investigate determinants of polypharmacy and to study the consistency of actual respiratory drug use with current Global Initiative for Chronic Obstructiv...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S24443

    authors: Franssen FM,Spruit MA,Wouters EF

    更新日期:2011-01-01 00:00:00

  • An evaluation of activity tolerance, patient-reported outcomes and satisfaction with the effectiveness of pulmonary daoyin on patients with chronic obstructive pulmonary disease.

    abstract:BACKGROUND AND OBJECTIVE:Pulmonary Daoyin (PD) (evolved from ancient Chinese daoyin skills), is a rehabilitation technology that combines specially designed movements of the arms and body and controlled breathing exercises, to improve the physiological and psychological status of patients with chronic respiratory disea...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2147/COPD.S117461

    authors: Zhang HL,Li JS,Yu XQ,Li SY,Halmurat U,Xie Y,Wang YF,Li FS,Wang MH

    更新日期:2017-08-04 00:00:00

  • Determining prognosis in acute exacerbation of COPD.

    abstract:BACKGROUND:Acute exacerbations are the leading causes of hospitalization and mortality in patients with COPD. Prognostic tools for patients with chronic COPD exist, but there are scarce data regarding acute exacerbations. We aimed to identify the prognostic factors of death and readmission after exacerbation of COPD. ...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S122382

    authors: Flattet Y,Garin N,Serratrice J,Perrier A,Stirnemann J,Carballo S

    更新日期:2017-01-31 00:00:00

  • Prevalence of Chronic Obstructive Pulmonary Disease and its Associated Factors in Nepal: Findings from a Community-based Household Survey.

    abstract:Background:Despite chronic obstructive pulmonary disease (COPD) being the commonest non-communicable disease in Nepal, there is limited research evidence estimating the spirometry-based burden of COPD. This study aims to estimate the prevalence of COPD and its correlates through a community-based survey in Pokhara Metr...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S268110

    authors: Adhikari TB,Acharya P,Högman M,Neupane D,Karki A,Drews A,Cooper BG,Sigsgaard T,Kallestrup P

    更新日期:2020-09-29 00:00:00

  • Prevalence of airflow limitation in subjects undergoing comprehensive health examination in Japan: Survey of Chronic Obstructive pulmonary disease Patients Epidemiology in Japan.

    abstract:PURPOSE:There are still evidence gaps on the prevalence of airflow limitation in Japan. The purpose of this survey was to estimate the prevalence of airflow limitation among healthy subjects in Japan and to show what proportion of subjects with airflow limitation had been diagnosed with chronic obstructive pulmonary di...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究

    doi:10.2147/COPD.S99935

    authors: Omori H,Kaise T,Suzuki T,Hagan G

    更新日期:2016-04-22 00:00:00

  • The relationship between anthropometric indicators and walking distance in patients with chronic obstructive pulmonary disease.

    abstract:BACKGROUND:Exercise intolerance is a major issue affecting many people with COPD. Six-minute walking distance (6MWD) is a widely used indicator of exercise capacity in patients with COPD. The process is strenuous and time-consuming, especially for patients who have muscle wasting. Anthropometric indicators that reflect...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S87714

    authors: Ho SC,Hsu MF,Kuo HP,Wang JY,Chen LF,Lee KY,Chuang HC

    更新日期:2015-09-08 00:00:00

  • Hyperinflated lungs compress the heart during expiration in COPD patients: a new finding on dynamic-ventilation computed tomography.

    abstract:Purpose:The aims of this study were to evaluate dynamic changes in heart size during the respiratory cycle using four-dimensional computed tomography (CT) and to understand the relationship of these changes to airflow limitation in smokers. Materials and methods:A total of 31 smokers, including 13 with COPD, underwent...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究

    doi:10.2147/COPD.S145599

    authors: Xu Y,Yamashiro T,Moriya H,Tsubakimoto M,Tsuchiya N,Nagatani Y,Matsuoka S,Murayama S

    更新日期:2017-10-26 00:00:00

  • Airflow obstruction: is it asthma or is it COPD?

    abstract::Despite the availability of guideline recommendations, diagnostic confusion between COPD and asthma appears common, and often it is very difficult to decide whether the obstruction is caused by asthma or COPD in a patient with airway obstruction. However, there are well-defined features that help in differentiating as...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,评审

    doi:10.2147/COPD.S54927

    authors: Rogliani P,Ora J,Puxeddu E,Cazzola M

    更新日期:2016-11-30 00:00:00

  • The Association Between Neighborhood Socioeconomic Disadvantage and Chronic Obstructive Pulmonary Disease.

    abstract:Rationale:Individual socioeconomic status has been shown to influence the outcomes of patients with chronic obstructive pulmonary disease (COPD). However, contextual factors may also play a role. The objective of this study is to evaluate the association between neighborhood socioeconomic disadvantage measured by the a...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S238933

    authors: Galiatsatos P,Woo H,Paulin LM,Kind A,Putcha N,Gassett AJ,Cooper CB,Dransfield MT,Parekh TM,Oates GR,Barr RG,Comellas AP,Han MK,Peters SP,Krishnan JA,Labaki WW,McCormack MC,Kaufman JD,Hansel NN

    更新日期:2020-05-05 00:00:00

  • Examining 30-day COPD readmissions through the emergency department.

    abstract:Background:Thirty-day readmission in COPD is common and costly, but potentially preventable. The emergency department (ED) may be a setting for COPD readmission reduction efforts. Objective:To better understand COPD readmission through the ED, ascertain factors associated with 30-day readmission through the ED, and id...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S147796

    authors: Rezaee ME,Ward CE,Nuanez B,Rezaee DA,Ditkoff J,Halalau A

    更新日期:2017-12-27 00:00:00

  • Gender-specific estimates of COPD prevalence: a systematic review and meta-analysis.

    abstract:Rationale:COPD has been perceived as being a disease of older men. However, >7 million women are estimated to live with COPD in the USA alone. Despite a growing body of literature suggesting an increasing burden of COPD in women, the evidence is limited. Objectives:To assess and synthesize the available evidence among...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,meta分析,评审

    doi:10.2147/COPD.S146390

    authors: Ntritsos G,Franek J,Belbasis L,Christou MA,Markozannes G,Altman P,Fogel R,Sayre T,Ntzani EE,Evangelou E

    更新日期:2018-05-10 00:00:00

  • Longitudinal changes in lung hyperinflation in COPD.

    abstract:PURPOSE:COPD is characterized by an accelerated and progressive decline in forced expiratory volume in 1 second (FEV1) and lung hyperinflation. Although lung hyperinflation is the hallmark of COPD, data on the longitudinal changes in lung hyperinflation and any association with the decline in FEV1 are lacking. The aim ...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S122909

    authors: Park J,Lee CH,Lee YJ,Park JS,Cho YJ,Lee JH,Lee CT,Yoon HI

    更新日期:2017-02-03 00:00:00

  • The view of pulmonologists on palliative care for patients with COPD: a survey study.

    abstract:INTRODUCTION:Early palliative care is not a common practice for patients with COPD. Important barriers are the identification of patients for palliative care and the organization of such care in this patient group. OBJECTIVE:Pulmonologists have a central role in providing good quality palliative care for patients with...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S121294

    authors: Duenk RG,Verhagen C,Dekhuijzen P,Vissers K,Engels Y,Heijdra Y

    更新日期:2017-01-17 00:00:00

  • Mean platelet volume as a predictor of pulmonary hypertension in patients with stable COPD.

    abstract::Background: Pulmonary hypertension (PH) is one of the most common complications developed during the course of chronic obstructive pulmonary disease (COPD). Platelet activation plays an important role in its pathophysiology, and mean platelet volume (MPV) is considered a respectable index of platelet activation. The a...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究

    doi:10.2147/COPD.S176413

    authors: Mohamed MF,Ali A,Abbas A,Awad MS,Gouda M,Sediq AM

    更新日期:2019-05-23 00:00:00

  • A gender difference in circulating neutrophils in malnourished patients with COPD.

    abstract:BACKGROUND:Circulating markers of inflammation in chronic obstructive pulmonary disease (COPD) may correlate to disease progression and extrapulmonary complications such as malnourishment. However, surprisingly little is known about gender-related differences for circulating inflammatory markers in COPD. PURPOSE:To ch...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S15351

    authors: Larsson S,Nordenson A,Glader P,Yoshihara S,Lindén A,Slinde F

    更新日期:2011-01-01 00:00:00