Abstract:
Background:Domiciliary noninvasive ventilation (NIV) use in stable hypercarbic COPD is becoming increasingly widespread. However, treatment compliance criteria and factors related to compliance remain to be defined. Methods:This research was designed as a prospective, cross-sectional, multicenter real-life study. Chronic hypercapnic COPD patients who were using domiciliary NIV for at least 1 year and being followed up in 19 centers across Turkey were included in the study. The patients who used NIV regularly, night or daytime and ≥5 hours/d, were classified as "high-compliance group," and patients who used NIV irregularly and <5 hours/d as "low-compliance group." Results:Two hundred and sixty-six patients with a mean age of 64.5±10.3 years were enrolled, of whom 75.2% were males. They were using domiciliary NIV for 2.8±2 years. Spontaneous time mode (p<0.001) and night use (p<0.001) were more frequent in the high-compliance group (n=163). Also, mean inspiratory positive airway pressure values of the high-compliance group were significantly higher than the low-compliance group (n=103; p<0.001). Cardiac failure (p=0.049) and obesity (p=0.01) were significantly more frequent in the high-compliance group. There were no difference between 2 groups regarding hospitalization, emergency department and intensive care unit admissions within the last year, as well as modified Medical Research Council dyspnea and COPD Assessment Test scores. With regard to NIV-related side effects, only conjunctivitis was observed more frequently in the high-compliance group (p=0.002). Conclusion:Determination of the patients who have better compliance to domiciliary NIV in COPD may increase the success and effectiveness of treatment. This highly comprehensive study on this topic possesses importance as it suggests that patient and ventilator characteristics may be related to treatment compliance.
journal_name
Int J Chron Obstruct Pulmon Disauthors
Yazar EE,Özlü T,Sarıaydın M,Taylan M,Ekici A,Aydın D,Coşgun İG,Durmuş Koçak Ndoi
10.2147/COPD.S164384subject
Has Abstractpub_date
2018-08-10 00:00:00pages
2367-2374eissn
1176-9106issn
1178-2005pii
copd-13-2367journal_volume
13pub_type
杂志文章,多中心研究abstract:Background:COPD is considered an independent risk factor for lung cancer. COPD and lung cancer are both very heterogeneous diseases, and the study herein investigates the link between COPD phenotypes and specific histological subtypes of lung cancer. Methods:This case-control study comprised 2,283 patients with newly ...
journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章
doi:10.2147/COPD.S158818
更新日期:2018-04-13 00:00:00
abstract:Background and objectives:Cognitive impairment is a common extrapulmonary comorbidity in COPD patients. The default mode network (DMN) plays a critical role in maintaining the normal activities of humans, and its function can be evaluated by resting state functional magnetic resonance imaging. The aim of this study was...
journal_title:International journal of chronic obstructive pulmonary disease
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doi:10.2147/COPD.S146870
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abstract:Purpose:The unpredictable trajectory of COPD can present challenges for patients when faced with a decision regarding a do-not-resuscitate (DNR) directive. The current retrospective analysis was conducted to investigate factors associated with an early DNR decision (prior to last hospital admission) and differences in ...
journal_title:International journal of chronic obstructive pulmonary disease
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doi:10.2147/COPD.S168049
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abstract::Chronic obstructive pulmonary disease (COPD) is a progressive chronic disease where treatment decisions should be based on disease severity and also should be equally distributed across age, gender, and social situation. The aim of this study was to determine to what extent patients with COPD are offered evidence-base...
journal_title:International journal of chronic obstructive pulmonary disease
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doi:10.2147/COPD.S115238
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abstract:BACKGROUND:The combination of umeclidinium (UMEC), a long-acting muscarinic receptor antagonist, and vilanterol (VI), a selective long-acting β₂ agonist, is in development for the treatment of chronic obstructive pulmonary disease (COPD). This study evaluated the pharmacokinetics, safety and tolerability, and pharmacod...
journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章,随机对照试验
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章
doi:10.2147/COPD.S57845
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journal_title:International journal of chronic obstructive pulmonary disease
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章
doi:10.2147/COPD.S214737
更新日期:2019-09-05 00:00:00
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journal_title:International journal of chronic obstructive pulmonary disease
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doi:10.2147/COPD.S268421
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章
doi:10.2147/COPD.S87015
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章
doi:10.2147/COPD.S167501
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章
doi:10.2147/COPD.S162484
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章
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journal_title:International journal of chronic obstructive pulmonary disease
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章
doi:10.2147/COPD.S152484
更新日期:2018-01-08 00:00:00
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章
doi:10.2147/COPD.S79264
更新日期:2015-10-01 00:00:00
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章
doi:10.2147/COPD.S122382
更新日期:2017-01-31 00:00:00
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章,多中心研究
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journal_title:International journal of chronic obstructive pulmonary disease
pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究
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更新日期:2017-10-26 00:00:00