Virtual Reality Rehabilitation in Patients with Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial.

Abstract:

Purpose:This study compared the effects of inpatient-based rehabilitation program of patients with chronic obstructive pulmonary disease (COPD) using non-immersive virtual reality (VR) training with a traditional pulmonary rehabilitation program. The aims of this study were to determine 1) whether rehabilitation featuring both VR as well as exercise training provides benefits over exercise training (ET) alone and 2) whether rehabilitation featuring VR training instead of exercise training provides equivalent benefits. Patients and Methods:The study recruited 106 patients with COPD to a 2-week high-intensity, five times a week intervention. Randomized into three groups, 34 patients participated in a traditional pulmonary rehabilitation program including endurance exercise training (ET), 38 patients participated in traditional pulmonary rehabilitation, including both endurance exercise training and virtual reality training (ET+VR) and 34 patients participated in pulmonary rehabilitation program including virtual reality training but no endurance exercise training (VR). The traditional pulmonary rehabilitation program consisted of fitness exercises, resistance respiratory muscle and relaxation training. Xbox 360® and Kinect® Adventures software were used for the VR training of lower and upper body strength, endurance, trunk control and dynamic balance. Comparison of the changes in the Senior Fitness Test was the primary outcome. Analysis was performed using linear mixed-effects models. Results:The comparison between ET and ET+VR groups showed that ET+VR group was superior to ET group in Arm Curl (p<0.003), Chair stand (p<0.008), Back scratch (p<0.002), Chair sit and reach (p<0.001), Up and go (p<0.000), 6-min walk test (p<0.011). Whereas, the comparison between ET and VR groups showed that VR group was superior to ET group in Arm Curl (p<0.000), Chair stand (p<0.001), 6-min walk test (p<0.031). Conclusion:Results suggest that pulmonary rehabilitation program supplemented with VR training is beneficial intervention to improve physical fitness in patients with COPD.

authors

Rutkowski S,Rutkowska A,Kiper P,Jastrzebski D,Racheniuk H,Turolla A,Szczegielniak J,Casaburi R

doi

10.2147/COPD.S223592

subject

Has Abstract

pub_date

2020-01-13 00:00:00

pages

117-124

eissn

1176-9106

issn

1178-2005

pii

223592

journal_volume

15

pub_type

杂志文章
  • Cardiovascular morbidity and the use of inhaled bronchodilators.

    abstract::We used the Manitoba Health database to examine the relationship between use of inhaled respiratory drugs in people with chronic obstructive respiratory diseases and cardiovascular hospitalizations from 1996 through 2000. The drugs examined were beta agonists [BA], ipratropium bromide IB, and inhaled steroids (ICS). E...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/copd.s1516

    authors: Macie C,Wooldrage K,Manfreda J,Anthonisen N

    更新日期:2008-01-01 00:00:00

  • Akt in the pathogenesis of COPD.

    abstract::In this review we consider the therapeutic potential of targeting Akt for the treatment of COPD. Akt is a serine/threonine protein kinase that functions as a signaling intermediate linked to multiple signaling programs involved in survival, inflammation, and growth. Akt is closely associated with key membrane-bound re...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,评审

    doi:10.2147/copd.2006.1.1.31

    authors: Bozinovski S,Vlahos R,Hansen M,Liu K,Anderson GP

    更新日期:2006-01-01 00:00:00

  • The COPD assessment test and St George's Respiratory Questionnaire: are they equivalent in subjects with COPD?

    abstract:BACKGROUND:The chronic obstructive pulmonary disease (COPD) assessment test (CAT) is a short questionnaire that has facilitated health status measurements in subjects with COPD. However, it remains controversial as to whether the CAT can be used as a suitable substitute for the St George's Respiratory Questionnaire (SG...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S104947

    authors: Morishita-Katsu M,Nishimura K,Taniguchi H,Kimura T,Kondoh Y,Kataoka K,Ogawa T,Watanabe F,Arizono S,Nishiyama O,Nakayasu K,Imaizumi K,Hasegawa Y

    更新日期:2016-07-07 00:00:00

  • Prevalence of airflow limitation in subjects undergoing comprehensive health examination in Japan: Survey of Chronic Obstructive pulmonary disease Patients Epidemiology in Japan.

    abstract:PURPOSE:There are still evidence gaps on the prevalence of airflow limitation in Japan. The purpose of this survey was to estimate the prevalence of airflow limitation among healthy subjects in Japan and to show what proportion of subjects with airflow limitation had been diagnosed with chronic obstructive pulmonary di...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究

    doi:10.2147/COPD.S99935

    authors: Omori H,Kaise T,Suzuki T,Hagan G

    更新日期:2016-04-22 00:00:00

  • Prevalence of undiagnosed airflow obstruction among people with a history of smoking in a primary care setting.

    abstract:PURPOSE:The purpose of this study was to define the prevalence of undiagnosed airflow obstruction (AO) among subjects with a history of smoking but no previous diagnosis of chronic lung disease. The finding of AO likely represents diagnosis of chronic obstructive pulmonary disease. PATIENTS:People aged ≥30 years with ...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究

    doi:10.2147/COPD.S106306

    authors: Fu SN,Yu WC,Wong CK,Lam MC

    更新日期:2016-09-27 00:00:00

  • Temperature Variability and Hospital Admissions for Chronic Obstructive Pulmonary Disease: Analysis of Attributable Disease Burden and Vulnerable Subpopulation.

    abstract:Purpose:Chronic obstructive pulmonary disease (COPD) is a major cause of chronic diseases causing considerable social and economic burden globally. Despite substantial evidence on temperature-COPD association, few studies have investigated the acute effect of temperature variability (TV), a potential trigger of exacerb...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S260988

    authors: Zhan ZY,Tian Q,Chen TT,Ye Y,Lin Q,Han D,Ou CQ

    更新日期:2020-09-22 00:00:00

  • COPD affects worker productivity and health care costs.

    abstract:Purpose:This study aimed to measure the true burden of COPD by calculating incremental direct and indirect costs. Direct medical resource use, productivity metrics, and COPD-specific resource use and costs were also evaluated. Patients and methods:This was a retrospective, observational, matched cohort study using adm...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S163795

    authors: Patel JG,Coutinho AD,Lunacsek OE,Dalal AA

    更新日期:2018-07-30 00:00:00

  • In Patients with Mild-to-Moderate COPD, Tobacco Smoking, and Not COPD, Is Associated with a Higher Risk of Cardiovascular Comorbidity.

    abstract:Background:Comorbidities including cardiovascular diseases are very common in chronic obstructive pulmonary disease (COPD) secondary to tobacco smoking and contribute to the overall severity of the disease. In non-smoking COPD, which accounts for about 25% of COPD cases worldwide, current knowledge on the frequency and...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S253417

    authors: Soumagne T,Guillien A,Roche N,Annesi-Maesano I,Andujar P,Laurent L,Jouneau S,Botebol M,Laplante JJ,Dalphin JC,Degano B

    更新日期:2020-07-01 00:00:00

  • Cigarette smoke extract induces placental growth factor release from human bronchial epithelial cells via ROS/MAPK (ERK-1/2)/Egr-1 axis.

    abstract::Etiological evidence demonstrates that there is a significant association between cigarette smoking and chronic airway inflammatory disease. Abnormal expression of placental growth factor (PlGF) has been reported in COPD, and its downstream signaling molecules have been reported to contribute to the pathogenesis of ai...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S120849

    authors: Wu D,Yuan Y,Lin Z,Lai T,Chen M,Li W,Lv Q,Yuan B,Li D,Wu B

    更新日期:2016-12-02 00:00:00

  • Evaluation of isokinetic muscle strength of upper limb and the relationship with pulmonary function and respiratory muscle strength in stable COPD patients.

    abstract:Background:Upper limb muscle strength plays an important role in respiratory and pulmonary function, and limited research focuses on the role of strength and endurance of the elbow extensor and flexor. This study was conducted to accurately assess upper limb muscle function and quantified associations with pulmonary fu...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S214737

    authors: Liu X,Li P,Wang Z,Lu Y,Li N,Xiao L,Duan H,Wang Z,Li J,Shan C,Wu W

    更新日期:2019-09-05 00:00:00

  • Effects of a COPD self-management support intervention: a randomized controlled trial.

    abstract:Background:This study examines the effects of the COPD-specific health promoting self-management intervention "Better living with COPD" on different self-management-related domains, self-efficacy, and sense of coherence (SOC). Methods:In a randomized controlled design, 182 people with COPD were allocated to either an ...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,随机对照试验

    doi:10.2147/COPD.S181005

    authors: Bringsvor HB,Langeland E,Oftedal BF,Skaug K,Assmus J,Bentsen SB

    更新日期:2018-11-08 00:00:00

  • Indices of iron homeostasis correlate with airway obstruction in an NHANES III cohort.

    abstract::Cigarette smoking results in the accumulation of iron both systemically and locally, in the lung thereby causing imbalance in iron homeostasis. This disruption in iron homeostasis can be associated with oxidative stress and consequent tissue injury. Therefore, in this study, we tested the association between iron home...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S138457

    authors: Ghio AJ,Hilborn ED

    更新日期:2017-07-18 00:00:00

  • Whole-body vibration training - better care for COPD patients: a systematic review and meta-analysis.

    abstract:Purpose:Whole-body vibrating training (WBVT) is a modality aiming to improve neuromuscular performance of patients with COPD. However, a consensus on the effects of WBVT has not been reached. We aimed to clarify the effects of WBVT on functional exercise capacity, pulmonary function, and quality of life in COPD patient...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,meta分析

    doi:10.2147/COPD.S176229

    authors: Zhou J,Pang L,Chen N,Wang Z,Wang C,Hai Y,Lyu M,Lai H,Lin F

    更新日期:2018-10-10 00:00:00

  • Anemia and performance status as prognostic markers in acute hypercapnic respiratory failure due to chronic obstructive pulmonary disease.

    abstract:BACKGROUND:In patients with acute hypercapnic respiratory failure (AHRF) during exacerbations of COPD, mortality can be high despite noninvasive ventilation (NIV). For some, AHRF is terminal and NIV is inappropriate. However there is no definitive method of identifying patients who are unlikely to survive. The aim of t...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S39403

    authors: Haja Mydin H,Murphy S,Clague H,Sridharan K,Taylor IK

    更新日期:2013-01-01 00:00:00

  • Microbiological airway colonization in COPD patients with severe emphysema undergoing endoscopic lung volume reduction.

    abstract:Background:Endoscopic lung volume reduction (eLVR) is a therapeutic option for selected patients with COPD and severe emphysema. Infectious exacerbations are serious events in these vulnerable patients; hence, prophylactic antibiotics are often prescribed postinterventionally. However, data on the microbiological airwa...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S150705

    authors: Trudzinski FC,Seiler F,Wilkens H,Metz C,Kamp A,Bals R,Gärtner B,Lepper PM,Becker SL

    更新日期:2017-12-19 00:00:00

  • Microarray Analysis of Long Non-Coding RNAs in Lung Tissues of Patients with COPD and HOXA-AS2 Promotes HPMECs Proliferation via Notch1.

    abstract:Background and Objectives:Long non-coding RNAs (lncRNAs) play an important role in the pathogenesis of many diseases, including cancer, pulmonary fibrosis and chronic obstructive pulmonary disease (COPD). In this study, we intended to identify the differentially expressed lncRNAs and the role of HOXA cluster antisense ...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S259601

    authors: Zhou AY,Zhao YY,Zhou ZJ,Duan JX,Zhu YZ,Cai S,Chen P

    更新日期:2020-10-09 00:00:00

  • Nebulized Colistin And Continuous Cyclic Azithromycin In Severe COPD Patients With Chronic Bronchial Infection Due To Pseudomonas aeruginosa: A Retrospective Cohort Study.

    abstract:Introduction:Long-term use of nebulized or oral antibiotics is common in the treatment of cystic fibrosis and non-cystic fibrosis bronchiectasis. To date, however, few studies have focused on the use of nebulized antibiotics in COPD patients. The aims of this study are: to establish whether a combination of nebulized c...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S209513

    authors: Montón C,Prina E,Pomares X,Cugat JR,Casabella A,Oliva JC,Gallego M,Monsó E

    更新日期:2019-10-17 00:00:00

  • The relationship between steps of 6MWT and COPD severity: a cross-sectional study.

    abstract:Background and objective:The distance of 6-minute walk test (D6MWT) has been widely used in the assessment of functional status in patients with COPD, while very little attention has been paid to the role of steps of 6-minute walk test (S6MWT). The purpose of this study was to investigate the relationship between S6MWT...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S188994

    authors: Zeng GS,Chen LC,Fan HZ,Wu LL,Wu XP,Fang ZK,He X,Yu HP

    更新日期:2018-12-28 00:00:00

  • Critical role of tumor necrosis factor receptor 1 in the pathogenesis of pulmonary emphysema in mice.

    abstract::COPD is a major cause of chronic morbidity and mortality throughout the world. Although tumor necrosis factor-α (TNF-α) has a critical role in the development of COPD, the role of different TNF receptors (TNFRs) in pulmonary emphysema has not been resolved. We aimed to clarify the role of TNFRs in the development of p...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S108919

    authors: Fujita M,Ouchi H,Ikegame S,Harada E,Matsumoto T,Uchino J,Nakanishi Y,Watanabe K

    更新日期:2016-07-28 00:00:00

  • COPD classification models and mortality prediction capacity.

    abstract:Objective:Our aim was to assess the impact of comorbidities on existing COPD prognosis scores. Patients and methods:A total of 543 patients with COPD (FEV1 <80% and FEV1/FVC <70%) were included between January 2003 and January 2004. Patients were stable for at least 6 weeks before inclusion and were followed for 5 yea...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S184695

    authors: Aramburu A,Arostegui I,Moraza J,Barrio I,Aburto M,García-Loizaga A,Uranga A,Zabala T,Quintana JM,Esteban C

    更新日期:2019-03-07 00:00:00

  • Distinct pain profiles in patients with chronic obstructive pulmonary disease.

    abstract:Background:Few studies have examined changes in the pain experience of patients with COPD and predictors of pain in these patients. Objectives:The objectives of the study were to examine whether distinct groups of COPD patients could be identified based on changes in the occurrence and severity of pain over 12 months ...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究

    doi:10.2147/COPD.S150114

    authors: Bentsen SB,Miaskowski C,Cooper BA,Christensen VL,Henriksen AH,Holm AM,Rustøen T

    更新日期:2018-03-06 00:00:00

  • Efficacy and safety of indacaterol/glycopyrronium in Japanese patients with COPD: a subgroup analysis from the SHINE study.

    abstract:BACKGROUND:COPD-related deaths are increasing in Japan, with ~5.3 million people at risk. METHODS:The SHINE was a 26-week, multicenter, randomized, double-blind, parallel-group study that evaluated safety and efficacy of indacaterol (IND)/glycopyrronium (GLY) 110/50 μg once daily (od) compared with GLY 50 μg od, IND 1...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2147/COPD.S111408

    authors: Hashimoto S,Ikeuchi H,Murata S,Kitawaki T,Ikeda K,Banerji D

    更新日期:2016-10-11 00:00:00

  • How do general practitioners implement decision-making regarding COPD patients with exacerbations? An international focus group study.

    abstract:PURPOSE:To explore the decision-making of general practitioners (GPs) concerning treatment with antibiotics and/or oral corticosteroids and hospitalization for COPD patients with exacerbations. METHODS:Thematic analysis of seven focus groups with 53 GPs from urban and rural areas in Norway, Germany, Wales, Poland, Rus...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究

    doi:10.2147/COPD.S118856

    authors: Laue J,Melbye H,Halvorsen PA,Andreeva EA,Godycki-Cwirko M,Wollny A,Francis NA,Spigt M,Kung K,Risør MB

    更新日期:2016-12-08 00:00:00

  • A 1-year follow-up study exploring the associations between perception of illness and health-related quality of life in persons with chronic obstructive pulmonary disease.

    abstract::Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disease with an increasing prevalence worldwide. Its potential consequences, including reduced function and reduced social participation, are likely to be associated with decreased health-related quality of life (HRQoL). However, illness percept...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S52700

    authors: Bonsaksen T,Haukeland-Parker S,Lerdal A,Fagermoen MS

    更新日期:2014-01-01 00:00:00

  • Predicting treatable traits for long-acting bronchodilators in patients with stable COPD.

    abstract:Purpose:There is currently no measure to predict a treatability of long-acting β-2 agonist (LABA) or long-acting muscarinic antagonist (LAMA) in patients with chronic obstructive pulmonary disease (COPD). We aimed to build prediction models for the treatment response to these bronchodilators, in order to determine the ...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2147/COPD.S151909

    authors: Kang J,Kim KT,Lee JH,Kim EK,Kim TH,Yoo KH,Lee JS,Kim WJ,Kim JH,Oh YM

    更新日期:2017-12-12 00:00:00

  • Prospective cross-sectional multicenter study on domiciliary noninvasive ventilation in stable hypercapnic COPD patients.

    abstract:Background:Domiciliary noninvasive ventilation (NIV) use in stable hypercarbic COPD is becoming increasingly widespread. However, treatment compliance criteria and factors related to compliance remain to be defined. Methods:This research was designed as a prospective, cross-sectional, multicenter real-life study. Chro...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章,多中心研究

    doi:10.2147/COPD.S164384

    authors: Yazar EE,Özlü T,Sarıaydın M,Taylan M,Ekici A,Aydın D,Coşgun İG,Durmuş Koçak N

    更新日期:2018-08-10 00:00:00

  • Relationship between airway obstruction and incidence of metabolic syndrome in Korea: a community-based cohort study.

    abstract:Background:Although studies have examined the relationship between metabolic syndrome (MetS) and COPD, the incidence of MetS in individuals with COPD has not specifically been investigated. This study aimed to evaluate the incidence of MetS in subjects with airway obstruction using data from a community-based cohort. ...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S157453

    authors: Kim CY,Park Y,Leem AY,Chung KS,Jung JY,Park MS,Kim YS

    更新日期:2018-06-28 00:00:00

  • Small airway dysfunction and flow and volume bronchodilator responsiveness in patients with chronic obstructive pulmonary disease.

    abstract:BACKGROUND:We investigated whether a relationship between small airways dysfunction and bronchodilator responsiveness exists in patients with chronic obstructive pulmonary disease (COPD). METHODS:We studied 100 (20 female; mean age: 68±10 years) patients with COPD (forced expiratory volume in 1 second [FEV1]: 55% pred...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S82509

    authors: Pisi R,Aiello M,Zanini A,Tzani P,Paleari D,Marangio E,Spanevello A,Nicolini G,Chetta A

    更新日期:2015-06-19 00:00:00

  • Increased risk of peripheral arterial occlusive diseases in patients with chronic obstructive pulmonary disease: a nationwide study in Taiwan.

    abstract:Objective:Chronic obstructive pulmonary disease (COPD) is associated with atherosclerosis. Previous studies including limited sample sizes have shown the prevalence of peripheral arterial occlusive disease (PAOD) among COPD patients. We sought to investigate the incidence of PAOD among COPD patients in Taiwan using a n...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S202029

    authors: Liao KM,Kuo LT,Lu HY

    更新日期:2019-07-04 00:00:00

  • A gender difference in circulating neutrophils in malnourished patients with COPD.

    abstract:BACKGROUND:Circulating markers of inflammation in chronic obstructive pulmonary disease (COPD) may correlate to disease progression and extrapulmonary complications such as malnourishment. However, surprisingly little is known about gender-related differences for circulating inflammatory markers in COPD. PURPOSE:To ch...

    journal_title:International journal of chronic obstructive pulmonary disease

    pub_type: 杂志文章

    doi:10.2147/COPD.S15351

    authors: Larsson S,Nordenson A,Glader P,Yoshihara S,Lindén A,Slinde F

    更新日期:2011-01-01 00:00:00