Exploring the Association Between Emphysema Phenotypes and Low Bone Mineral Density in Smokers with and without COPD.

abstract：:Clinical trials of a combination therapy of an inhaled corticosteroid, fluticasone propionate (FP), with a long-acting beta2-agonist, salmeterol (Sal), have demonstrated a greater improvement in lung function and in quality of life measures after the combination compared with either component of alone. In a subanalysi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chung KF

更新日期：2006-01-01 00:00:00

abstract：Introduction:Training in correct inhaler use, ideally in person or by video demonstration, can minimize errors but is rarely provided in clinics. This open-label, low-intervention study evaluated critical error rates with dry-powder inhalers (DPIs), before and after training, in patients with chronic obstructive pulmon...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Collier DJ,Wielders P,van der Palen J,Heyes L,Midwinter D,Collison K,Preece A,Barnes N,Sharma R

更新日期：2020-06-09 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is associated with an increased cardiovascular risk. However, the mechanisms for this association are yet unclear. The aim of this study was to investigate the relationship between brachial intima-media thickness (B-IMT), an independent predictor of cardiovascular...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Urban MH,Eickhoff P,Funk GC,Burghuber OC,Wolzt M,Valipour A

更新日期：2017-01-04 00:00:00

abstract：:TRPM8 plays a key role in COPD. The development of pulmonary hypertension (PH) in COPD adversely affects survival and exercise capacity. Thus, the aim of this study was to evaluate the possible association between single nucleotide polymorphisms (SNPs) in TRPM8 and COPD or PH in COPD among the Chinese Han population. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xiong M,Wang J,Guo M,Zhou Q,Lu W

更新日期：2016-10-14 00:00:00

abstract：Purpose:This study compared the effects of inpatient-based rehabilitation program of patients with chronic obstructive pulmonary disease (COPD) using non-immersive virtual reality (VR) training with a traditional pulmonary rehabilitation program. The aims of this study were to determine 1) whether rehabilitation featur...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Rutkowski S,Rutkowska A,Kiper P,Jastrzebski D,Racheniuk H,Turolla A,Szczegielniak J,Casaburi R

更新日期：2020-01-13 00:00:00

abstract：BACKGROUND:It was reported that autonomic nervous system function is altered in subjects with chronic obstructive pulmonary disease (COPD). We evaluated short- and long-term fractal exponents of heart rate variability (HRV) in COPD subjects. PATIENTS AND METHODS:We analyzed data from 30 volunteers, who were divided in...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Carvalho TD,Pastre CM,de Godoy MF,Fereira C,Pitta FO,de Abreu LC,Ramos EM,Valenti VE,Vanderlei LC

更新日期：2011-01-06 00:00:00

abstract：OBJECTIVE:β-Blockers are safe and improve survival in patients with both congestive heart failure (CHF) and COPD. However, the superiority of different types of β-blockers is still unclear among patients with CHF and COPD. The association between β-blockers and CHF exacerbation as well as COPD exacerbation remains uncl...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liao KM,Lin TY,Huang YB,Kuo CC,Chen CY

更新日期：2017-08-26 00:00:00

abstract：Background:Patients with chronic obstructive pulmonary disease (COPD) often have poor health-related quality of life (HRQoL) that is disproportionate to their degree of airflow limitation. This study evaluated the association between St George's Respiratory Questionnaire for COPD (SGRQ-C) score and forced expiratory vo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lee H,Jhun BW,Cho J,Yoo KH,Lee JH,Kim DK,Lee JD,Jung KS,Lee JY,Park HY

更新日期：2017-11-13 00:00:00

abstract：Introduction and aim:Abnormal brain structure and function in COPD has been reported on MRI. However, the deficit in local synchronization of spontaneous activity in patients with stable COPD remains unknown. The main aim of the present study was to explore spontaneous brain activity in patients with COPD compared with...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xin H,Li H,Yu H,Yu J,Zhang J,Wang W,Peng D

更新日期：2019-02-27 00:00:00

abstract：:Impaired physical performance is common in chronic obstructive pulmonary disease (COPD), but its assessment can be difficult in routine clinical practice. We compared the timed up and go (TUG) test and other easily applied assessments of physical performance with the 6-minute walk distance (6MWD). In a longitudinal st...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Albarrati AM,Gale NS,Enright S,Munnery MM,Cockcroft JR,Shale DJ

更新日期：2016-08-02 00:00:00

abstract：Purpose:Patients with COPD might be particularly susceptible to hypoxia-induced autonomic dysregulation. Decreased baroreflex sensitivity (BRS) and increased blood pressure (BP) variability (BPV) are markers of impaired cardiovascular autonomic regulation and there is evidence for an association between decreased BRS/i...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Schwarz EI,Latshang TD,Furian M,Flück D,Segitz S,Müller-Mottet S,Ulrich S,Bloch KE,Kohler M

更新日期：2019-03-14 00:00:00

abstract：BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) often have multiple underlying comorbidities, which may lead to increased health care resource utilization (HCRU) and costs. OBJECTIVE:To describe the comorbidity profiles of COPD patients and examine the associations between the presence of comorbi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Schwab P,Dhamane AD,Hopson SD,Moretz C,Annavarapu S,Burslem K,Renda A,Kaila S

更新日期：2017-02-23 00:00:00

abstract：:Abstract: Static lung hyperinflation has important clinical consequences in patients with chronic obstructive pulmonary disease (COPD). Given that most of these patients have respiratory and peripheral muscle weakness, dyspnea and functional exercise capacity may improve as a result of inspiratory muscle training (IMT...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Shahin B,Germain M,Kazem A,Annat G

更新日期：2008-01-01 00:00:00

abstract：:[This corrects the article on p. 3485 in vol. 13, PMID: 30498338.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2018-12-05 00:00:00

abstract：:Noninvasive ventilation (NIV) has been one of the major advances in respiratory medicine in the last decade. NIV improves quality of life, prolongs survival, and improves gas exchange and sleep quality in restrictive patients, but evidence available now does not allow us to establish clear criteria for prescribing NIV...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Díaz-Lobato S,Alises SM,Rodríguez EP

更新日期：2006-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease of the lung caused primarily by exposure to cigarette smoke. Clinically, it presents with progressive cough, sputum production, dyspnea, reduced exercise capacity, and diminished quality of life. Physiologically, it is characterized by...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sharafkhaneh A,Mattewal AS,Abraham VM,Dronavalli G,Hanania NA

更新日期：2010-10-05 00:00:00

abstract：INTRODUCTION:Noninvasive ventilation (NIV) improves survival among patients with hypercapnic respiratory failure in hospital, but evidence for its use in domiciliary settings is limited. A patient's underlying risk of having an exacerbation may affect any potential benefit that can be gained from domiciliary NIV. This ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Dretzke J,Moore D,Dave C,Mukherjee R,Price MJ,Bayliss S,Wu X,Jordan RE,Turner AM

更新日期：2016-09-16 00:00:00

abstract：:COPD is a major cause of chronic morbidity and mortality throughout the world. Although tumor necrosis factor-α (TNF-α) has a critical role in the development of COPD, the role of different TNF receptors (TNFRs) in pulmonary emphysema has not been resolved. We aimed to clarify the role of TNFRs in the development of p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Fujita M,Ouchi H,Ikegame S,Harada E,Matsumoto T,Uchino J,Nakanishi Y,Watanabe K

更新日期：2016-07-28 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD), a respiratory disease characterized by a progressive decline in lung function, is considered to be a leading cause of morbidity and mortality. Long-acting inhaled bronchodilators, such as long-acting β2 agonists (LABAs) or long-acting muscarinic antagonists (LAMAs), are th...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ramadan WH,Kabbara WK,El Khoury GM,Al Assir SA

更新日期：2015-10-30 00:00:00

abstract：BACKGROUND:indacaterol is a novel, inhaled once-daily ultra-long-acting β(2)-agonist for the treatment of chronic obstructive pulmonary disease (COPD). OBJECTIVES:this study compared the onset of action of single doses of indacaterol 150 and 300 μg with salbutamol 200 μg, salmeterol-fluticasone 50/500 μg, and placebo ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Balint B,Watz H,Amos C,Owen R,Higgins M,Kramer B,INSURE Study Investigators.

更新日期：2010-09-07 00:00:00

abstract：BACKGROUND:Polypharmacy of respiratory medications is commonly observed in patients with chronic obstructive pulmonary disease (COPD). The aims of this study were to investigate determinants of polypharmacy and to study the consistency of actual respiratory drug use with current Global Initiative for Chronic Obstructiv...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Franssen FM,Spruit MA,Wouters EF

更新日期：2011-01-01 00:00:00

abstract：Purpose:Autophagy plays essential roles in the development of COPD. We aim to identify and validate the potential autophagy-related genes of COPD through bioinformatics analysis and experiment validation. Methods:The mRNA expression profile dataset GSE38974 was obtained from GEO database. The potential differentially ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sun S,Shen Y,Wang J,Li J,Cao J,Zhang J

更新日期：2021-01-12 00:00:00

abstract：:COPD is a worsening condition that leads to a pathologic degeneration of the respiratory system. It represents one of the most important causes of mortality and morbidity in the world, and it is characterized by the presence of associated comorbidity. This article analyzes gastroesophageal reflux disease (GERD) and lo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bordoni B,Marelli F,Morabito B,Sacconi B,Caiazzo P,Castagna R

更新日期：2018-01-17 00:00:00

abstract：OBJECTIVES:Emphysema is one of the prognostic factors for rapid lung function decline in patients with COPD, but the impact of incidentally detected emphysema on population without spirometric abnormalities has not been evaluated. This study aimed to determine whether emphysema detected upon computed tomography (CT) sc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Koo HK,Jin KN,Kim DK,Chung HS,Lee CH

更新日期：2016-01-29 00:00:00

abstract：Background:Microparticles (MPs) are shedding membrane vesicles released from activated blood and endothelial cells under inflammatory conditions. The role of endothelial MPs (EMPs) in pathophysiology of COPD is relatively well known. However, the release and function of MPs of other cellular origins, eg, platelets, red...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tőkés-Füzesi M,Ruzsics I,Rideg O,Kustán P,Kovács GL,Molnár T

更新日期：2018-11-15 00:00:00

abstract：Purpose:Chronic obstructive pulmonary disease (COPD) is a major cause of chronic diseases causing considerable social and economic burden globally. Despite substantial evidence on temperature-COPD association, few studies have investigated the acute effect of temperature variability (TV), a potential trigger of exacerb...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhan ZY,Tian Q,Chen TT,Ye Y,Lin Q,Han D,Ou CQ

更新日期：2020-09-22 00:00:00

abstract：Purpose:Improvement in the diagnosis of asthma and chronic obstructive pulmonary disease (COPD) overlap (ACO), and identification of biomarkers for phenotype recognition will encourage good patient care by providing optimal therapy. We investigated club cell secretory protein (CC-16), a protective and anti-inflammatory...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Oh JY,Lee YS,Min KH,Hur GY,Lee SY,Kang KH,Rhee CK,Park SJ,Shim JJ

更新日期：2018-10-18 00:00:00

abstract：Background:This study examines the effects of the COPD-specific health promoting self-management intervention "Better living with COPD" on different self-management-related domains, self-efficacy, and sense of coherence (SOC). Methods:In a randomized controlled design, 182 people with COPD were allocated to either an ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bringsvor HB,Langeland E,Oftedal BF,Skaug K,Assmus J,Bentsen SB

更新日期：2018-11-08 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Alpha-1-antitrypsin deficiency (AATD) is associated with a high risk for the development of early-onset emphysema and liver disease. A large majority of subjects with severe AATD carry the ZZ genotype, which can be easily detected. Another rare pathologic variant, the Mmalton allele, causes a ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Belmonte I,Barrecheguren M,López-Martínez RM,Esquinas C,Rodríguez E,Miravitlles M,Rodríguez-Frías F

更新日期：2016-10-11 00:00:00

abstract：OBJECTIVE:Comorbidities are characteristic of COPD. However, little is known about the secondary manifestations of COPD in the gastrointestinal tract. Therefore, we aimed to explore the long-term effects of gastrectomy in patients with spirometry-defined COPD or those at risk of COPD. PARTICIPANTS:Subjects included 87...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Saito H,Nomura K,Abe S,Motegi T,Ishii T,Hattori K,Kusunoki Y,Gemma A,Kida K

更新日期：2015-10-29 00:00:00