Lung function decline in COPD.

abstract：Background and Objectives:Long non-coding RNAs (lncRNAs) play an important role in the pathogenesis of many diseases, including cancer, pulmonary fibrosis and chronic obstructive pulmonary disease (COPD). In this study, we intended to identify the differentially expressed lncRNAs and the role of HOXA cluster antisense ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhou AY,Zhao YY,Zhou ZJ,Duan JX,Zhu YZ,Cai S,Chen P

更新日期：2020-10-09 00:00:00

abstract：PURPOSE:COPD remains under-recognized and under-treated. Much of early COPD care is given by primary care physicians but only when COPD is recognized. This survey explores the attitudes, beliefs, and knowledge related to COPD recognition, diagnosis, and treatment from family physicians and nurse practitioners (NPs) and...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Yawn BP,Wollan PC

更新日期：2008-01-01 00:00:00

abstract：Purpose:On March 16, 2020, the Spanish government declared a state of alarm due to the rapid spread of coronavirus disease 2019 (COVID-19). Patients with chronic obstructive pulmonary disease (COPD) were restricted to remain confined at home, and medical visits were cancelled for 3 months. The impact of this lockdown o...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pleguezuelos E,Del Carmen A,Moreno E,Ortega P,Vila X,Ovejero L,Serra-Prat M,Palomera E,Garnacho-Castaño MV,Loeb E,Farago G,Miravitlles M

更新日期：2020-10-23 00:00:00

abstract：BACKGROUND:Assessment of dyspnea in COPD patients relies in clinical practice on the modified Medical Research Council (mMRC) scale, whereas the Baseline Dyspnea Index (BDI) is mainly used in clinical trials. Little is known on the correspondence between the two methods. METHODS:Cross-sectional analysis was carried ou...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Perez T,Burgel PR,Paillasseur JL,Caillaud D,Deslée G,Chanez P,Roche N,INITIATIVES BPCO Scientific Committee.

更新日期：2015-08-18 00:00:00

abstract：BACKGROUND:The relationship between prior health care utilization and respiratory medication prescriptions in an unselected population of patients with COPD is not known. METHODS:We determined the prescribed respiratory medications and respiratory and nonrespiratory health care encounters in 523 Veterans with COPD at ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Seaman J,Leonard AC,Panos RJ

更新日期：2010-04-07 00:00:00

abstract：Purpose:Depression is reported in association with chronic obstructive pulmonary disease (COPD). However, to date, no multidimensional indices have taken depression into consideration to predict COPD patients' prognosis. This study aimed to determine whether a new multidimensional index named CODEXS, based on comorbidi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Deng D,Zhou A,Chen P,Shuang Q

更新日期：2020-02-03 00:00:00

abstract：:COPD is a common complex disease characterized by progressive airflow limitation. Several genome-wide association studies (GWASs) have discovered genes that are associated with COPD. Recently, candidate genes for COPD identified by GWASs include CHRNA3/5 (cholinergic nicotine receptor alpha 3/5), IREB2 (iron regulator...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim WJ,Lee SD

更新日期：2015-10-19 00:00:00

abstract：Purpose:Peripheral blood eosinophilic counts are susceptible to many factors and have variability over time. There are limited studies on association of blood eosinophilia with long-term mortality of chronic obstructive pulmonary disease (COPD) patients and these results remain controversial. Our aims were to explore t...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhang Y,Liang LR,Zhang S,Lu Y,Chen YY,Shi HZ,Lin YX

更新日期：2020-05-19 00:00:00

abstract：Rationale:Emphysema and osteoporosis are tobacco-related diseases. Many studies have shown that emphysema is a strong and independent predictor of low bone mineral density (BMD) in smokers; however, none of them explored its association with different emphysema subtypes. Objective:To explore the association between th...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Gonzalez J,Rivera-Ortega P,Rodríguez-Fraile M,Restituto P,Colina I,Calleja MLD,Alcaide AB,Campo A,Bertó J,Seijo L,Pérez-Warnisher MT,Zulueta JJ,Varo N,de-Torres JP

更新日期：2020-07-27 00:00:00

abstract：BACKGROUND:It was reported that autonomic nervous system function is altered in subjects with chronic obstructive pulmonary disease (COPD). We evaluated short- and long-term fractal exponents of heart rate variability (HRV) in COPD subjects. PATIENTS AND METHODS:We analyzed data from 30 volunteers, who were divided in...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Carvalho TD,Pastre CM,de Godoy MF,Fereira C,Pitta FO,de Abreu LC,Ramos EM,Valenti VE,Vanderlei LC

更新日期：2011-01-06 00:00:00

abstract：Background:Exacerbations explain much of the cost of COPD. Higher blood eosinophil cell counts at admission for acute exacerbation of COPD increase the risk of subsequent exacerbations and hospitalizations. However, there is no literature on the economic burden of patients with this inflammatory profile. The objective ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Poder TG,Carrier N,Bélanger M,Couillard S,Courteau J,Larivée P,Vanasse A

更新日期：2018-10-08 00:00:00

abstract：BACKGROUND:Concerns have been raised that treatment of COPD with inhaled corticosteroids may increase pneumonia risk. Responding to a request from the European Medicines Agency Pharmacovigilance Risk Assessment Committee, a pooled analysis of interventional studies compared pneumonia risk with inhaled budesonide-contai...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hollis S,Jorup C,Lythgoe D,Martensson G,Regnell P,Eckerwall G

更新日期：2017-04-05 00:00:00

abstract：:The purpose of this study was to compare the relative efficacy and safety of different antibiotic drugs and recommend superior regimens in the treatment of bronchitis. With respect to the antibiotic comparisons against quinolones in terms of intention-to-treat patients, we concluded that quinolones had advantages over...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wang J,Xu H,Liu P,Li M

更新日期：2017-08-09 00:00:00

abstract：Introduction:Long-term oxygen therapy (LTOT) improves survival and may reduce hospital admissions in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia, but the impact of daily duration of LTOT on hospitalization rate is unknown. We aimed to estimate the association between the daily durati...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sundh J,Ahmadi Z,Ekström M

更新日期：2018-08-28 00:00:00

abstract：:Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) released an updated document in 2017 that excluded the spirometric parameter in the classification of patients. The validity of this new classification system in predicting mortality and respiratory hospitalization is still uncertain. Method...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lee SJ,Yun SS,Ju S,You JW,Cho YJ,Jeong YY,Kim JY,Kim HC,Lee JD

更新日期：2019-04-29 00:00:00

abstract：:Chronic bronchitis is a relatively common entity among patients with underlying chronic obstructive lung disease. Typical treatment includes pulmonary hygiene, bronchodilators, and antimicrobial therapy. In recent years, the duration of antimicrobial therapy in acute exacerbations of COPD has become shorter and shorte...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Milstone AP

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:While cross-national studies have documented rates of chronic obstructive pulmonary disease (COPD) misdiagnosis among patients in primary care, US studies are scarce. Studies investigating diagnosis among uninsured patients are lacking. OBJECTIVE:The purpose of this study is to identify patients who are o...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ghattas C,Dai A,Gemmel DJ,Awad MH

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Effects of pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) patients with severely impaired health status are poorly documented since these patients are usually excluded from clinical trials. This retrospective, observational study aims to study the impact of disease on health ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van Ranst D,Otten H,Meijer JW,van 't Hul AJ

更新日期：2011-01-01 00:00:00

abstract：Purpose:Patients with COPD might be particularly susceptible to hypoxia-induced autonomic dysregulation. Decreased baroreflex sensitivity (BRS) and increased blood pressure (BP) variability (BPV) are markers of impaired cardiovascular autonomic regulation and there is evidence for an association between decreased BRS/i...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Schwarz EI,Latshang TD,Furian M,Flück D,Segitz S,Müller-Mottet S,Ulrich S,Bloch KE,Kohler M

更新日期：2019-03-14 00:00:00

abstract：Introduction:Understanding the breadth of patients' support needs is important for the delivery of person-centered care, particularly in progressive long-term conditions such as chronic obstructive pulmonary disease (COPD). Existing reviews identify important aspects of managing life with COPD with which patients may n...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Gardener AC,Ewing G,Kuhn I,Farquhar M

更新日期：2018-03-26 00:00:00

abstract：:[This corrects the article on p. 2749 in vol. 11, PMID: 27853362.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND AND OBJECTIVE:It is known that biomarkers of systemic inflammation are raised in COPD caused by tobacco (T-COPD) compared with healthy controls, but there is less information on the inflammatory status of subjects with COPD caused by biomass smoke (B-COPD). In addition, the possible (if any) differences in i...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Golpe R,Martín-Robles I,Sanjuán-López P,Pérez-de-Llano L,González-Juanatey C,López-Campos JL,Arellano-Orden E

更新日期：2017-09-01 00:00:00

abstract：:Clinical trials of a combination therapy of an inhaled corticosteroid, fluticasone propionate (FP), with a long-acting beta2-agonist, salmeterol (Sal), have demonstrated a greater improvement in lung function and in quality of life measures after the combination compared with either component of alone. In a subanalysi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chung KF

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Noncommunicable diseases have become a public heath problem in India concomitant with economic development, leading to increases in tobacco consumption, obesity, and changes in diet and lifestyle. Although observation suggests that tobacco consumption is a major risk factor for deaths due to circulatory, pul...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Singh RB,Singh S,Chattopadhya P,Singh K,Singhz V,Kulshrestha SK,Tomar RS,Kumar R,Singh G,Mechirova V,Pella D

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND AIM:Patients with advanced chronic obstructive pulmonary disease (COPD) have poor quality of life. The aim of this study was to assess the effects of proactive palliative care on the well-being of these patients. TRIAL REGISTRATION:This trial is registered with the Netherlands Trial Register, NTR4037. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Duenk RG,Verhagen C,Bronkhorst EM,van Mierlo P,Broeders M,Collard SM,Dekhuijzen P,Vissers K,Heijdra Y,Engels Y

更新日期：2017-09-28 00:00:00

abstract：BACKGROUND:Management of chronic incurable diseases such as chronic obstructive pulmonary disease (COPD) and asthma is difficult. Incorporation of patient preferences is widely encouraged. PURPOSE:To summarize original research articles determining patient preference in moderate-to-severe disease. METHODS:Acceptable ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bereza BG,Troelsgaard Nielsen A,Valgardsson S,Hemels ME,Einarson TR

更新日期：2015-04-08 00:00:00

abstract：Background:Patients with chronic obstructive pulmonary disease (COPD) and cardiovascular comorbidities may have an increased risk of medication-related cardiac arrhythmias. We therefore performed an analysis of Holter electrocardiogram (ECG) data from two large, long-term, controlled clinical COPD trials to investigate...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Andreas S,Bothner U,de la Hoz A,Kloer I,Trampisch M,Alter P

更新日期：2020-08-10 00:00:00

abstract：Background:Phase III studies demonstrated efficacy and safety of nebulized glycopyrrolate inhalation solution (GLY) in subjects with COPD. Secondary analyses were performed to examine the effect of background long-acting beta2-agonist (LABA) use on the efficacy and safety of nebulized GLY. Methods:In two 12-week place...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kerwin EM,Tosiello R,Price B,Sanjar S,Goodin T

更新日期：2018-09-19 00:00:00

abstract：Purpose:Whole-body vibrating training (WBVT) is a modality aiming to improve neuromuscular performance of patients with COPD. However, a consensus on the effects of WBVT has not been reached. We aimed to clarify the effects of WBVT on functional exercise capacity, pulmonary function, and quality of life in COPD patient...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhou J,Pang L,Chen N,Wang Z,Wang C,Hai Y,Lyu M,Lai H,Lin F

更新日期：2018-10-10 00:00:00

abstract：BACKGROUND:COPD is one of the most common chronic diseases, and more and more farmers who were frequently exposed to greenhouse environments were diagnosed with COPD. However, little information is available on the prevalence of COPD among the greenhouse farmers. This study was conducted to assess the prevalence of COP...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liu S,Ren Y,Wen D,Chen Y,Chen D,Li L,Zhang X,Zhang Y,Fu S,Li Z,Xia S,Wang D,Chen H,Zhao J,Wang X

更新日期：2015-10-01 00:00:00