Over diagnosis of chronic obstructive pulmonary disease in an underserved patient population.

abstract：Background:The DYNAGITO study was a Phase IIIb, randomized, double-blind, multicenter, active-controlled, parallel-group, 52-week study designed to determine the efficacy and safety of tiotropium and olodaterol combination therapy (TIO+OLO 5/5 μg) versus tiotropium monotherapy (TIO 5 μg) for reducing moderate-to-severe...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ichinose M,Nishimura M,Akimoto M,Kurotori Y,Zhao Y,de la Hoz A,Mishima M

更新日期：2018-07-13 00:00:00

abstract：:Impaired physical performance is common in chronic obstructive pulmonary disease (COPD), but its assessment can be difficult in routine clinical practice. We compared the timed up and go (TUG) test and other easily applied assessments of physical performance with the 6-minute walk distance (6MWD). In a longitudinal st...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Albarrati AM,Gale NS,Enright S,Munnery MM,Cockcroft JR,Shale DJ

更新日期：2016-08-02 00:00:00

abstract：:COPD is a common complex disease characterized by progressive airflow limitation. Several genome-wide association studies (GWASs) have discovered genes that are associated with COPD. Recently, candidate genes for COPD identified by GWASs include CHRNA3/5 (cholinergic nicotine receptor alpha 3/5), IREB2 (iron regulator...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim WJ,Lee SD

更新日期：2015-10-19 00:00:00

abstract：:COPD exerts a substantial burden on health and health care systems globally and will continue to do so for the foreseeable future. Treatment however can be costly and health care providers are interested in both whether treatments can offer improvements in disease burden and whether they represent value for money. Eco...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Starkie HJ,Briggs AH,Chambers MG

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether long-term intermittent azithromycin therapy reduces the frequency of exacerbation in severe chronic obstructive pulmonary disease (COPD). METHODS:We retrospectively investigated the clinical benefits of long-term azithromycin (500 mg orally three times per week...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pomares X,Montón C,Espasa M,Casabon J,Monsó E,Gallego M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The use of chlorofluorocarbons (CFCs) has contributed to the depletion of the stratospheric ozone layer resulting in serious health concerns. Ipratropium bromide/salbutamol sulphate CFC-pressurized metered-dose inhalers (IB/SAL-CFC pMDI) have been in widespread use for many years without any apparent ill con...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bhattacharya A,Bhargava S,Singh V,Talwar D,Whig J,Rebello J,Purandare S,Gogtay J

更新日期：2016-06-30 00:00:00

abstract：:The landmark study of Fletcher and Peto on the natural history of tobacco smoke-related chronic airflow obstruction suggested that decline in the forced expiratory volume in the first second (FEV(1)) in chronic obstructive pulmonary disease (COPD) is slow at the beginning, becoming faster with more advanced disease. T...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tantucci C,Modina D

更新日期：2012-01-01 00:00:00

abstract：Background:Since most internal medicine nurses work with chronic obstructive pulmonary disease (COPD) patients daily, their ability to meet the needs of COPD patients is an important issue. Our study aimed to assess COPD-related knowledge in internal medicine nurses. Methods:A descriptive cross-sectional study includi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ma Y,Peng Y,Chen P,Nie N,Chen Y

更新日期：2019-12-17 00:00:00

abstract：INTRODUCTION:According to guidelines, the diagnosis of COPD should be confirmed by post-bronchodilator (post-BD) airway obstruction on spirometry; however, in clinical practice, this is not always performed. The aim of this population-based study was to compare clinical characteristics and prognosis, assessed as mortal...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sawalha S,Hedman L,Rönmark E,Lundbäck B,Lindberg A

更新日期：2017-04-24 00:00:00

abstract：BACKGROUND:To estimate the potential cost savings by following the current Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline recommendations in patients being treated for chronic obstructive pulmonary disease (COPD) with the combination of long-acting β(2)-agonist (LABA), long-acting muscarinic an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Asche CV,Leader S,Plauschinat C,Raparla S,Yan M,Ye X,Young D

更新日期：2012-01-01 00:00:00

abstract：Background:The use of inhaled corticosteroid (ICS) in patients with chronic obstructive pulmonary disease (COPD) decreases the frequency of COPD exacerbations. Recently, pneumonia was reported as a complication of ICS in patients with COPD. However, there have been few reports concerning the relationship between ICS an...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hirano R,Fujita M,Matsumoto T,On R,Watanabe K

更新日期：2018-10-23 00:00:00

abstract：BACKGROUND:Lung volume reduction (LVR) improves breathing mechanics by reducing hyperinflation. Lobar selection usually focuses on choosing the most destroyed emphysematous lobes as seen on an inspiratory CT scan. However, it has never been shown to what extent these densitometric CT parameters predict the least deflat...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hetzel J,Boeckeler M,Horger M,Ehab A,Kloth C,Wagner R,Freitag L,Slebos DJ,Lewis RA,Haentschel M

更新日期：2017-08-30 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory condition, and progresses with acute exacerbations. (AE). During AE, levels of acute phase reactants such as C-reactive protein (CRP) and inflammatory cells in the circulation increase. Soluble urokinase-type plasminogen activator recepto...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Gumus A,Altintas N,Cinarka H,Kirbas A,Hazıroglu M,Karatas M,Sahin U

更新日期：2015-02-13 00:00:00

abstract：Rationale:Emphysema and osteoporosis are tobacco-related diseases. Many studies have shown that emphysema is a strong and independent predictor of low bone mineral density (BMD) in smokers; however, none of them explored its association with different emphysema subtypes. Objective:To explore the association between th...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Gonzalez J,Rivera-Ortega P,Rodríguez-Fraile M,Restituto P,Colina I,Calleja MLD,Alcaide AB,Campo A,Bertó J,Seijo L,Pérez-Warnisher MT,Zulueta JJ,Varo N,de-Torres JP

更新日期：2020-07-27 00:00:00

abstract：BACKGROUND:With the growing burden of COPD and associated morbidity and mortality, a need for self-management has been identified. The Self-management Programme of Activity, Coping and Education for Chronic Obstructive Pulmonary Disease (SPACE for COPD) manual was developed to support self-management in COPD patients. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Blackmore C,Johnson-Warrington VL,Williams JE,Apps LD,Young HM,Bourne C,Singh SJ

更新日期：2017-06-07 00:00:00

abstract：:[This corrects the article on p. 2749 in vol. 11, PMID: 27853362.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2017-01-10 00:00:00

abstract：Purpose:We compared clinical characteristics of COPD patients according to symptom variability and evaluated the effect of symptom variability during the first year of enrollment on clinical outcomes of COPD. Methods:We analyzed COPD patients' data from the Korean Obstructive Lung Disease (KOLD) cohort. Symptom variab...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim MA,Suh MK,Park J,Kim JH,Kim TH,Kim EK,Oh YM,Lee SD,Lee JH

更新日期：2019-09-20 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality, and health care expenditure worldwide. Relaxation of airway smooth muscle with inhaled bronchodilators is the cornerstone of treatment for stable COPD, with inhaled corticosteroids reserved for those with a history of exacerbation...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cohen JS,Miles MC,Donohue JF,Ohar JA

更新日期：2016-04-15 00:00:00

abstract：Background and objective:The distance of 6-minute walk test (D6MWT) has been widely used in the assessment of functional status in patients with COPD, while very little attention has been paid to the role of steps of 6-minute walk test (S6MWT). The purpose of this study was to investigate the relationship between S6MWT...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zeng GS,Chen LC,Fan HZ,Wu LL,Wu XP,Fang ZK,He X,Yu HP

更新日期：2018-12-28 00:00:00

abstract：Background:Frailty can inform management approaches for individuals with COPD. However, inpatient measures of frailty are seldom employed because they are time-consuming or inapplicable for bed-bound patients. We investigated the feasibility and potential of an innovative sensor-based upper-extremity function (UEF) tes...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ehsani H,Mohler MJ,Golden T,Toosizadeh N

更新日期：2018-12-18 00:00:00

abstract：Background:Health effects of electronic cigarette (EC) use in patients with chronic obstructive pulmonary disease (COPD) are largely unexplored. Aim:We present findings from a long-term prospective assessment of respiratory parameters in a cohort of COPD patients who ceased or substantially reduced conventional cigare...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Polosa R,Morjaria JB,Prosperini U,Russo C,Pennisi A,Puleo R,Caruso M,Caponnetto P

更新日期：2018-08-22 00:00:00

abstract：:Etiological evidence demonstrates that there is a significant association between cigarette smoking and chronic airway inflammatory disease. Abnormal expression of placental growth factor (PlGF) has been reported in COPD, and its downstream signaling molecules have been reported to contribute to the pathogenesis of ai...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wu D,Yuan Y,Lin Z,Lai T,Chen M,Li W,Lv Q,Yuan B,Li D,Wu B

更新日期：2016-12-02 00:00:00

abstract：Background:People living with both chronic obstructive pulmonary disease (COPD) and frailty have high potential to benefit from exercise-based interventions, including pulmonary rehabilitation, but face challenges completing them. Research to understand ways to optimise exercise-based interventions in this group is lac...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Brighton LJ,Evans CJ,Man WDC,Maddocks M

更新日期：2020-04-20 00:00:00

abstract：BACKGROUND:Concerns have been raised that treatment of COPD with inhaled corticosteroids may increase pneumonia risk. Responding to a request from the European Medicines Agency Pharmacovigilance Risk Assessment Committee, a pooled analysis of interventional studies compared pneumonia risk with inhaled budesonide-contai...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hollis S,Jorup C,Lythgoe D,Martensson G,Regnell P,Eckerwall G

更新日期：2017-04-05 00:00:00

abstract：BACKGROUND:Forced expiratory volume in 1 second (FEV1)/forced expiratory volume in 6 seconds (FEV6) has been proposed as an alternative to FEV1/forced vital capacity (FVC) for detecting airway obstruction. A fixed cut-off value for FEV1/FEV6 in a Korean population is lacking. We investigated a fixed cut-off for FEV1/FE...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chung KS,Jung JY,Park MS,Kim YS,Kim SK,Chang J,Song JH

更新日期：2016-08-19 00:00:00

abstract：INTRODUCTION:Randomized interventional trials generally recruit highly selected patients. In contrast, long-term, noninterventional studies can reflect standard of care of real-life populations. DACCORD (Die ambulante Versorgung mit langwirksamen Bronchodilatatoren: COPD-Register in Deutschland [Outpatient Care With Lo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Buhl R,Criée CP,Kardos P,Vogelmeier C,Lossi N,Mailänder C,Worth H

更新日期：2016-07-20 00:00:00

abstract：BACKGROUND:The causal association between depression, anxiety, and health-related quality of life (HRQoL) in chronic obstructive pulmonary disease (COPD) is unclear. We therefore conducted a systematic review of prospective cohort studies that measured depression, anxiety, and HRQoL in COPD. METHODS:Electronic databas...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Blakemore A,Dickens C,Guthrie E,Bower P,Kontopantelis E,Afzal C,Coventry PA

更新日期：2014-05-20 00:00:00

abstract：Aim:The aim of the current study was to assess the serum levels of trace minerals/heavy metals in COPD patients with and without pulmonary hypertension (PH) and to investigate their correlations to demographic, clinical, and biochemical variables. Materials and methods:This cross-sectional study was performed in Van Y...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Asker S,Asker M,Yeltekin AC,Aslan M,Ozbay B,Demir H,Turan H

更新日期：2018-05-31 00:00:00

abstract：Objective:Our aim was to assess the impact of comorbidities on existing COPD prognosis scores. Patients and methods:A total of 543 patients with COPD (FEV1 <80% and FEV1/FVC <70%) were included between January 2003 and January 2004. Patients were stable for at least 6 weeks before inclusion and were followed for 5 yea...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Aramburu A,Arostegui I,Moraza J,Barrio I,Aburto M,García-Loizaga A,Uranga A,Zabala T,Quintana JM,Esteban C

更新日期：2019-03-07 00:00:00

abstract：Aim:Six-minute walking test distance (6MWD) and body mass index, obstruction, dyspnea and exercise (BODE) index are measures of functional status in COPD patients, but require space, time and patient's compliance. Exhaled volatile organic compounds (VOCs) analysis via electronic nose is a quick and easy method that has...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Finamore P,Pedone C,Scarlata S,Di Paolo A,Grasso S,Santonico M,Pennazza G,Antonelli Incalzi R

更新日期：2018-05-01 00:00:00