Profile of fluticasone furoate/vilanterol dry powder inhaler combination therapy as a potential treatment for COPD.

abstract：:Abstract: Static lung hyperinflation has important clinical consequences in patients with chronic obstructive pulmonary disease (COPD). Given that most of these patients have respiratory and peripheral muscle weakness, dyspnea and functional exercise capacity may improve as a result of inspiratory muscle training (IMT...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Shahin B,Germain M,Kazem A,Annat G

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:Chronic obstructive pulmonary disease (COPD) related to wood smoke exposure is characterized by important inflammation of the central and peripheral airways without significant emphysema. The objective of this study is to describe the bronchial hyperresponsiveness (BHR) level in women with COPD related to wood ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： González-García M,Torres-Duque CA,Bustos A,Jaramillo C,Maldonado D

更新日期：2012-01-01 00:00:00

abstract：Purpose:Acute exacerbation of COPD (AECOPD) is among the most frequent causes for hospital admission, causing morbidity and mortality. Infection is the most frequent cause, and studies on pollution have shown higher hospital admission and mortality with inconsistent results. The objective was to identify if there is a ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Morantes-Caballero JA,Fajardo Rodriguez HA

更新日期：2019-07-11 00:00:00

abstract：BACKGROUND:Despite the availability of national and international guidelines, evidence suggests that chronic obstructive pulmonary disease (COPD) treatment is not always prescribed according to recommendations. This study evaluated the current management of patients with COPD using a large UK primary-care database. ME...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Price D,West D,Brusselle G,Gruffydd-Jones K,Jones R,Miravitlles M,Rossi A,Hutton C,Ashton VL,Stewart R,Bichel K

更新日期：2014-08-27 00:00:00

abstract：BACKGROUND:COPD is a debilitating disease that affects patients' daily lives. One's daily physical activity (DPA) decreases due to multifactorial causes, and this decrease is correlated with a poor prognosis in COPD patients. Muscle wasting may at least be partly due to increased activity of the ubiquitin proteasome pa...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lee KY,Chen TT,Chiang LL,Chuang HC,Feng PH,Liu WT,Chen KY,Ho SC

更新日期：2017-05-22 00:00:00

abstract：INTRODUCTION:Noninvasive ventilation (NIV) improves survival among patients with hypercapnic respiratory failure in hospital, but evidence for its use in domiciliary settings is limited. A patient's underlying risk of having an exacerbation may affect any potential benefit that can be gained from domiciliary NIV. This ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Dretzke J,Moore D,Dave C,Mukherjee R,Price MJ,Bayliss S,Wu X,Jordan RE,Turner AM

更新日期：2016-09-16 00:00:00

abstract：Purpose:There is currently no measure to predict a treatability of long-acting β-2 agonist (LABA) or long-acting muscarinic antagonist (LAMA) in patients with chronic obstructive pulmonary disease (COPD). We aimed to build prediction models for the treatment response to these bronchodilators, in order to determine the ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kang J,Kim KT,Lee JH,Kim EK,Kim TH,Yoo KH,Lee JS,Kim WJ,Kim JH,Oh YM

更新日期：2017-12-12 00:00:00

abstract：Background:Telerehabilitation (TR) aimed at patients with COPD has shown promising effects on symptoms, physical function, and quality of life, but little research has been conducted to understand the impact of implementation on frontline health professionals. Therefore, the aim of this study was to examine the barrier...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Damhus CS,Emme C,Hansen H

更新日期：2018-08-17 00:00:00

abstract：PURPOSE:Endobronchial valve (EBV) therapy is increasingly being seen as a therapeutic option for advanced emphysema, but its clinical utility in Asian populations, who may have different phenotypes to other ethnic populations, has not been assessed. PATIENTS AND METHODS:This prospective open-label single-arm clinical ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Park TS,Hong Y,Lee JS,Oh SY,Lee SM,Kim N,Seo JB,Oh YM,Lee SD,Lee SW

更新日期：2015-07-29 00:00:00

abstract：:[This corrects the article on p. 3485 in vol. 13, PMID: 30498338.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2018-12-05 00:00:00

abstract：BACKGROUND:Polypharmacy of respiratory medications is commonly observed in patients with chronic obstructive pulmonary disease (COPD). The aims of this study were to investigate determinants of polypharmacy and to study the consistency of actual respiratory drug use with current Global Initiative for Chronic Obstructiv...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Franssen FM,Spruit MA,Wouters EF

更新日期：2011-01-01 00:00:00

abstract：:We hypothesized that bronchodilator treatment not only improves hyperinflation and endurance capacity but also muscular efficiency in stable chronic obstructive pulmonary disease (COPD). We aimed to demonstrate that tiotropium and salmeterol improve muscular efficiency compared with placebo. Twenty-five COPD patients ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van der Vaart H,Postma DS,Grevink R,Roemer W,ten Hacken N

更新日期：2011-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD), a respiratory disease characterized by a progressive decline in lung function, is considered to be a leading cause of morbidity and mortality. Long-acting inhaled bronchodilators, such as long-acting β2 agonists (LABAs) or long-acting muscarinic antagonists (LAMAs), are th...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ramadan WH,Kabbara WK,El Khoury GM,Al Assir SA

更新日期：2015-10-30 00:00:00

abstract：BACKGROUND:The syndrome of combined pulmonary fibrosis and emphysema (CPFE) is a recently described entity associating upper-lobe emphysema and lower-lobe fibrosis. We sought to evaluate differences in pulmonary function between CPFE patients with and without airflow obstruction. SUBJECTS AND METHODS:Thirty-one CPFE p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kitaguchi Y,Fujimoto K,Hanaoka M,Honda T,Hotta J,Hirayama J

更新日期：2014-07-29 00:00:00

abstract：BACKGROUND:Nowadays, there is increasing awareness about the frequent chronic comorbidities in patients with chronic obstructive pulmonary disease (COPD) but little information is available to quantify the burden of illness that these conditions cause in this population. We aimed to identify and describe a population s...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Anecchino C,Rossi E,Fanizza C,De Rosa M,Tognoni G,Romero M,working group ARNO project.

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:There are still evidence gaps on the prevalence of airflow limitation in Japan. The purpose of this survey was to estimate the prevalence of airflow limitation among healthy subjects in Japan and to show what proportion of subjects with airflow limitation had been diagnosed with chronic obstructive pulmonary di...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Omori H,Kaise T,Suzuki T,Hagan G

更新日期：2016-04-22 00:00:00

abstract：:Influenza viruses cause respiratory tract infections that in patients with underlying lung diseases such as chronic obstructive pulmonary disease (COPD) are associated with exacerbations and excess morbidity and mortality. Typically, influenza B is associated with relatively mild, local outbreaks, whereas influenza A ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wesseling G

更新日期：2007-01-01 00:00:00

abstract：:Impaired physical performance is common in chronic obstructive pulmonary disease (COPD), but its assessment can be difficult in routine clinical practice. We compared the timed up and go (TUG) test and other easily applied assessments of physical performance with the 6-minute walk distance (6MWD). In a longitudinal st...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Albarrati AM,Gale NS,Enright S,Munnery MM,Cockcroft JR,Shale DJ

更新日期：2016-08-02 00:00:00

abstract：Background:Since most internal medicine nurses work with chronic obstructive pulmonary disease (COPD) patients daily, their ability to meet the needs of COPD patients is an important issue. Our study aimed to assess COPD-related knowledge in internal medicine nurses. Methods:A descriptive cross-sectional study includi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ma Y,Peng Y,Chen P,Nie N,Chen Y

更新日期：2019-12-17 00:00:00

abstract：BACKGROUND:COPD is a major cause of death and morbidity worldwide, and is characterized by persistent airflow obstruction. The evaluation of obstruction is critically dependent on sensitive methods for lung-function testing. A wide body of knowledge has been accumulated in recent years showing that these methods have b...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lopes AJ,de Melo PL

更新日期：2016-07-11 00:00:00

abstract：Background:Airway inflammation may drive the progression of chronic obstructive pulmonary disease (COPD) associated with alpha-1 antitrypsin deficiency (AATD), but the relationship between airway microbiota and inflammation has not been investigated. Methods:We studied 21 non-treated AATD (AATD-noT) patients, 20 AATD-...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Balbi B,Sangiorgi C,Gnemmi I,Ferrarotti I,Vallese D,Paracchini E,Delle Donne L,Corda L,Baderna P,Corsico A,Carone M,Brun P,Cappello F,Ricciardolo FL,Ruggeri P,Mumby S,Adcock IM,Caramori G,Di Stefano A

更新日期：2019-08-21 00:00:00

abstract：Background:Domiciliary noninvasive ventilation (NIV) use in stable hypercarbic COPD is becoming increasingly widespread. However, treatment compliance criteria and factors related to compliance remain to be defined. Methods:This research was designed as a prospective, cross-sectional, multicenter real-life study. Chro...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Yazar EE,Özlü T,Sarıaydın M,Taylan M,Ekici A,Aydın D,Coşgun İG,Durmuş Koçak N

更新日期：2018-08-10 00:00:00

abstract：Background:COPD is considered an independent risk factor for lung cancer. COPD and lung cancer are both very heterogeneous diseases, and the study herein investigates the link between COPD phenotypes and specific histological subtypes of lung cancer. Methods:This case-control study comprised 2,283 patients with newly ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wang W,Xie M,Dou S,Cui L,Zheng C,Xiao W

更新日期：2018-04-13 00:00:00

abstract：Introduction:Self-management (SM) is a core component of well-being and perceived health for patients with chronic obstructive pulmonary disease (COPD). Most theories on SM share that self-efficacy, illness-perception and coping are determinants of SM behavior. Optimal support to improve SM should be tailored to the in...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Voorhaar M,Tiemensma J,Asijee GM,Slok AHM,Muris JWM,Kaptein AA

更新日期：2020-06-19 00:00:00

abstract：Purpose:To date, no consensus exists on the effects of systemic steroid use on pneumonic chronic obstructive pulmonary disease (COPD) exacerbation owing to trial design issues in previous trials involving these conditions. This multicenter study aimed to evaluate more precisely the effectiveness of the use of systemic ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Shiroshita A,Shiba H,Tanaka Y,Nishi A,Sato K,Shirakawa C,Kataoka Y

更新日期：2020-10-19 00:00:00

abstract：Purpose:We hypothesized that increased level of serum β2-microglobulin (β2M) is an independent factor associated with higher mortality in hospitalized patients with exacerbated chronic obstructive pulmonary disease (COPD). Patients and Methods:We retrospectively analyzed 488 hospitalized patients with exacerbated COPD...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Mao W,Wang J,Zhang L,Wang Y,Wang W,Zeng N,Zhang J,Li Q,Jiao F,Li J,Cui N,Mi S,Xue Y,Wang Z,Ying S,Huang K

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:Limited mobility is a risk factor for developing chronic obstructive pulmonary disease (COPD)-related disabilities. Little is known about the validity of the Short Physical Performance Battery (SPPB) for identifying mobility limitations in patients with COPD. OBJECTIVE:To determine the clinical validity of ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bernabeu-Mora R,Medina-Mirapeix F,Llamazares-Herrán E,García-Guillamón G,Giménez-Giménez LM,Sánchez-Nieto JM

更新日期：2015-12-03 00:00:00

abstract：:Clinical trials of a combination therapy of an inhaled corticosteroid, fluticasone propionate (FP), with a long-acting beta2-agonist, salmeterol (Sal), have demonstrated a greater improvement in lung function and in quality of life measures after the combination compared with either component of alone. In a subanalysi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chung KF

更新日期：2006-01-01 00:00:00

abstract：Rationale:Individual socioeconomic status has been shown to influence the outcomes of patients with chronic obstructive pulmonary disease (COPD). However, contextual factors may also play a role. The objective of this study is to evaluate the association between neighborhood socioeconomic disadvantage measured by the a...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Galiatsatos P,Woo H,Paulin LM,Kind A,Putcha N,Gassett AJ,Cooper CB,Dransfield MT,Parekh TM,Oates GR,Barr RG,Comellas AP,Han MK,Peters SP,Krishnan JA,Labaki WW,McCormack MC,Kaufman JD,Hansel NN

更新日期：2020-05-05 00:00:00

abstract：Purpose:Patients with COPD might be particularly susceptible to hypoxia-induced autonomic dysregulation. Decreased baroreflex sensitivity (BRS) and increased blood pressure (BP) variability (BPV) are markers of impaired cardiovascular autonomic regulation and there is evidence for an association between decreased BRS/i...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Schwarz EI,Latshang TD,Furian M,Flück D,Segitz S,Müller-Mottet S,Ulrich S,Bloch KE,Kohler M

更新日期：2019-03-14 00:00:00