Prevalence of chronic obstructive pulmonary disease and pattern of comorbidities in a general population.

abstract：Background and objective:The distance of 6-minute walk test (D6MWT) has been widely used in the assessment of functional status in patients with COPD, while very little attention has been paid to the role of steps of 6-minute walk test (S6MWT). The purpose of this study was to investigate the relationship between S6MWT...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zeng GS,Chen LC,Fan HZ,Wu LL,Wu XP,Fang ZK,He X,Yu HP

更新日期：2018-12-28 00:00:00

abstract：Background and purpose:While the efficacy and safety of combined tiotropium and olodaterol in patients with COPD was established in a large clinical trial program, it is important to assess whether clinical data can be applied to geographic patient groups, particularly for East Asian patients who may have a different p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bai C,Ichinose M,Lee SH,Lee KH,Jöns O,Bothner U,Zhao Y,Buhl R

更新日期：2017-11-20 00:00:00

abstract：Background:The risk of dying of lung cancer is up to eightfold higher in patients with COPD than in age- and gender-matched controls. The aim of this study was to investigate the factors associated with lung cancer in a large cohort of COPD patients from primary care centers. Methods:To analyze whether age, gender, so...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sandelin M,Mindus S,Thuresson M,Lisspers K,Ställberg B,Johansson G,Larsson K,Janson C

更新日期：2018-06-06 00:00:00

abstract：:Clinical trials of a combination therapy of an inhaled corticosteroid, fluticasone propionate (FP), with a long-acting beta2-agonist, salmeterol (Sal), have demonstrated a greater improvement in lung function and in quality of life measures after the combination compared with either component of alone. In a subanalysi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chung KF

更新日期：2006-01-01 00:00:00

abstract：Purpose:This study investigated the effect of dual bronchodilation with the long-acting β-receptor agonist/long-acting muscarinic antagonist combination, indacaterol/glycopyrronium (IND/GLY), on nighttime oxygenation, lung function, sleep quality, and symptoms in patients with moderate-to-severe COPD. Patients and met...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lehmann S,Ringbæk T,Løkke A,Grote L,Hedner J,Lindberg E

更新日期：2019-01-09 00:00:00

abstract：Purpose:Improvement in the diagnosis of asthma and chronic obstructive pulmonary disease (COPD) overlap (ACO), and identification of biomarkers for phenotype recognition will encourage good patient care by providing optimal therapy. We investigated club cell secretory protein (CC-16), a protective and anti-inflammatory...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Oh JY,Lee YS,Min KH,Hur GY,Lee SY,Kang KH,Rhee CK,Park SJ,Shim JJ

更新日期：2018-10-18 00:00:00

abstract：Objective:To determine the clinical and economic consequences of inhaled corticosteroid doses and particle size in patients on triple-inhalation therapy for COPD. Methods:Patients aged ≥40 years who initiated treatment with multi-inhaler triple-inhaled therapy between 1 January 2015 and 31 March were included and foll...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sicras-Mainar A,de Abajo FJ,Izquierdo-Alonso JL

更新日期：2020-12-09 00:00:00

abstract：Background:Exacerbations explain much of the cost of COPD. Higher blood eosinophil cell counts at admission for acute exacerbation of COPD increase the risk of subsequent exacerbations and hospitalizations. However, there is no literature on the economic burden of patients with this inflammatory profile. The objective ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Poder TG,Carrier N,Bélanger M,Couillard S,Courteau J,Larivée P,Vanasse A

更新日期：2018-10-08 00:00:00

abstract：Purpose:miR-190a-5p expression alters dynamically in response to hypoxia. However, the role of miR-190a-5p expression in hypoxia-induced pulmonary hypertension (PH) remains unclear. We sought to correlate the miR-190a-5p expression levels with the severity, diagnosis, and prognosis of PH in relation to chronic obstruct...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jiang J,Xia Y,Liang Y,Yang M,Zeng W,Zeng X

更新日期：2018-11-20 00:00:00

abstract：:TRPM8 plays a key role in COPD. The development of pulmonary hypertension (PH) in COPD adversely affects survival and exercise capacity. Thus, the aim of this study was to evaluate the possible association between single nucleotide polymorphisms (SNPs) in TRPM8 and COPD or PH in COPD among the Chinese Han population. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xiong M,Wang J,Guo M,Zhou Q,Lu W

更新日期：2016-10-14 00:00:00

abstract：Objectives:To describe the trends in pharmacologic treatment for patients newly diagnosed with chronic obstructive pulmonary disease (COPD) in Alberta, Canada. Methods:We linked Alberta health databases to identify patients aged ≥35 years with incident COPD between April 2010 and March 2017. Incident cases were define...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Tran DT,Akpinar I,Mayers I,Makhinova T,Jacobs P

更新日期：2019-09-26 00:00:00

abstract：Rationale:Individual socioeconomic status has been shown to influence the outcomes of patients with chronic obstructive pulmonary disease (COPD). However, contextual factors may also play a role. The objective of this study is to evaluate the association between neighborhood socioeconomic disadvantage measured by the a...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Galiatsatos P,Woo H,Paulin LM,Kind A,Putcha N,Gassett AJ,Cooper CB,Dransfield MT,Parekh TM,Oates GR,Barr RG,Comellas AP,Han MK,Peters SP,Krishnan JA,Labaki WW,McCormack MC,Kaufman JD,Hansel NN

更新日期：2020-05-05 00:00:00

abstract：Purpose:This study compared the effects of inpatient-based rehabilitation program of patients with chronic obstructive pulmonary disease (COPD) using non-immersive virtual reality (VR) training with a traditional pulmonary rehabilitation program. The aims of this study were to determine 1) whether rehabilitation featur...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Rutkowski S,Rutkowska A,Kiper P,Jastrzebski D,Racheniuk H,Turolla A,Szczegielniak J,Casaburi R

更新日期：2020-01-13 00:00:00

abstract：BACKGROUND:Long-acting inhaled bronchodilators, including anticholinergic tiotropium, are recommended for the maintenance therapy of chronic obstructive pulmonary disease (COPD). It has been shown in a number of studies that treatment with tiotropium alleviates symptoms, improves exercise tolerance, health status, and ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Jahnz-Różyk K,Szepiel P

更新日期：2015-03-18 00:00:00

abstract：:Background: Qualitative research provides real-life information on patients' condition and facilitates informed design of future clinical studies. Objective: We used Online Communities as a qualitative research tool to evaluate the effect of cough and mucus on COPD patients. Methods: Two 2-week Online Communities were...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cook N,Gey J,Oezel B,Mackay AJ,Kumari C,Kaur VP,Larkin N,Harte J,Vergara-Muro S,Gutzwiller FS

更新日期：2019-06-24 00:00:00

abstract：Purpose:We hypothesized that increased level of serum β2-microglobulin (β2M) is an independent factor associated with higher mortality in hospitalized patients with exacerbated chronic obstructive pulmonary disease (COPD). Patients and Methods:We retrospectively analyzed 488 hospitalized patients with exacerbated COPD...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Mao W,Wang J,Zhang L,Wang Y,Wang W,Zeng N,Zhang J,Li Q,Jiao F,Li J,Cui N,Mi S,Xue Y,Wang Z,Ying S,Huang K

更新日期：2020-04-07 00:00:00

abstract：:Regenerative or stem cell therapy is an emerging field of treatment based on stimulation of endogenous resident stem cells or administration of exogenous stem cells to treat diseases or injury and to replace malfunctioning or damaged tissues. Current evidence suggests that in the lung, these cells may participate in t...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lipsi R,Rogliani P,Calzetta L,Segreti A,Cazzola M

更新日期：2014-12-12 00:00:00

abstract：BACKGROUND:The combination of umeclidinium (UMEC), a long-acting muscarinic receptor antagonist, and vilanterol (VI), a selective long-acting β₂ agonist, is in development for the treatment of chronic obstructive pulmonary disease (COPD). This study evaluated the pharmacokinetics, safety and tolerability, and pharmacod...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Mehta R,Kelleher D,Preece A,Hughes S,Crater G

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Pulmonary emphysema causes several electrocardiogram changes, and one of the most common and well known is on the frontal P-wave axis. P-axis verticalization (P-axis > 60°) serves as a quasidiagnostic indicator of emphysema. The correlation of P-axis verticalization with the radiological severity of emphys...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Chhabra L,Chaubey VK,Kothagundla C,Bajaj R,Kaul S,Spodick DH

更新日期：2013-01-01 00:00:00

abstract：Purpose:There is currently no measure to predict a treatability of long-acting β-2 agonist (LABA) or long-acting muscarinic antagonist (LAMA) in patients with chronic obstructive pulmonary disease (COPD). We aimed to build prediction models for the treatment response to these bronchodilators, in order to determine the ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kang J,Kim KT,Lee JH,Kim EK,Kim TH,Yoo KH,Lee JS,Kim WJ,Kim JH,Oh YM

更新日期：2017-12-12 00:00:00

abstract：Background:Adherence to treatment is key to achieve desired outcomes. In COPD, adherence is generally suboptimal and is impaired by treatment complexity. Objective:To estimate the clinical and economic impact of an improvement in treatment adherence due to an increased use of once-daily single-inhaler triple therapy (...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Miravitlles M,Marín A,Huerta A,Carcedo D,Villacampa A,Puig-Junoy J

更新日期：2020-07-10 00:00:00

abstract：Purpose:To evaluate clinical periodontal status and microbiologic pathogens in patients with chronic obstructive pulmonary disease (COPD) and periodontitis. Patients and Methods:We conducted a case-control study of 60 periodontitis patients with COPD (case group) and 60 periodontitis patients with normal pulmonary fun...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhou X,Wang J,Liu W,Huang X,Song Y,Wang Z,Jia X

更新日期：2020-09-03 00:00:00

abstract：:Cigarette smoking results in the accumulation of iron both systemically and locally, in the lung thereby causing imbalance in iron homeostasis. This disruption in iron homeostasis can be associated with oxidative stress and consequent tissue injury. Therefore, in this study, we tested the association between iron home...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ghio AJ,Hilborn ED

更新日期：2017-07-18 00:00:00

abstract：Purpose:Autophagy plays essential roles in the development of COPD. We aim to identify and validate the potential autophagy-related genes of COPD through bioinformatics analysis and experiment validation. Methods:The mRNA expression profile dataset GSE38974 was obtained from GEO database. The potential differentially ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sun S,Shen Y,Wang J,Li J,Cao J,Zhang J

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:It has been scientifically proven that pulmonary rehabilitation improves exercise tolerance and facilitates the carrying out of daily physical activities. To optimize the physical and physiological benefits, it is necessary to individualize the training intensity for each patient. The aim of this study is to...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Fabre C,Chehere B,Bart F,Mucci P,Wallaert B,Grosbois JM

更新日期：2017-05-16 00:00:00

abstract：BACKGROUND:indacaterol is a novel, inhaled once-daily ultra-long-acting β(2)-agonist for the treatment of chronic obstructive pulmonary disease (COPD). OBJECTIVES:this study compared the onset of action of single doses of indacaterol 150 and 300 μg with salbutamol 200 μg, salmeterol-fluticasone 50/500 μg, and placebo ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Balint B,Watz H,Amos C,Owen R,Higgins M,Kramer B,INSURE Study Investigators.

更新日期：2010-09-07 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality. Current therapies confer partial benefits either by incompletely improving airflow limitation or by reducing acute exacerbations, hence new therapies are desirable. In the absence of robust early predictors of clinical efficacy, ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van der Merwe R,Molfino NA

更新日期：2012-01-01 00:00:00

abstract：:[This corrects the article on p. 1401 in vol. 12, PMID: 28546748.]. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors：

更新日期：2019-01-18 00:00:00

abstract：Purpose:On March 16, 2020, the Spanish government declared a state of alarm due to the rapid spread of coronavirus disease 2019 (COVID-19). Patients with chronic obstructive pulmonary disease (COPD) were restricted to remain confined at home, and medical visits were cancelled for 3 months. The impact of this lockdown o...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Pleguezuelos E,Del Carmen A,Moreno E,Ortega P,Vila X,Ovejero L,Serra-Prat M,Palomera E,Garnacho-Castaño MV,Loeb E,Farago G,Miravitlles M

更新日期：2020-10-23 00:00:00

abstract：OBJECTIVES:Emphysema is one of the prognostic factors for rapid lung function decline in patients with COPD, but the impact of incidentally detected emphysema on population without spirometric abnormalities has not been evaluated. This study aimed to determine whether emphysema detected upon computed tomography (CT) sc...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Koo HK,Jin KN,Kim DK,Chung HS,Lee CH

更新日期：2016-01-29 00:00:00